Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
Times Cited: 1797
Times Cited: 1797
Times Cited
Times Co-cited
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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
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TET-mediated active DNA demethylation: mechanism, function and beyond.
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5-Hydroxymethylcytosine is a predominantly stable DNA modification.
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Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Michael Williams, Adele Murrell, Shankar Balasubramanian. Nat Chem 2014
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Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
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5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
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Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.
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Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites.
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MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.
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Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates.
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Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
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Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
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Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.
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The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes.
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Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.
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UHRF1 plays a role in maintaining DNA methylation in mammalian cells.
Magnolia Bostick, Jong Kyong Kim, Pierre-Olivier Estève, Amander Clark, Sriharsa Pradhan, Steven E Jacobsen. Science 2007
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Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis.
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The discovery of 5-formylcytosine in embryonic stem cell DNA.
Toni Pfaffeneder, Benjamin Hackner, Matthias Truss, Martin Münzel, Markus Müller, Christian A Deiml, Christian Hagemeier, Thomas Carell. Angew Chem Int Ed Engl 2011
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Quantification of the sixth DNA base hydroxymethylcytosine in the brain.
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Role of TET enzymes in DNA methylation, development, and cancer.
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
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Structural insight into substrate preference for TET-mediated oxidation.
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Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals.
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Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase.
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Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation.
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Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain.
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Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution.
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Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.
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TET2 promotes histone O-GlcNAcylation during gene transcription.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.