You Zhi Qu, Min Li, Yan Ling Zhao, Zhen Wei Zhao, Xiao Yan Wei, Jin Ping Liu, Li Gao, Guo Dong Gao. Eur J Pharmacol 2009
Times Cited: 77
Times Cited: 77
Times Cited
Times Co-cited
Similarity
Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia.
Yumin Luo, Zhen Qin, Zhen Hong, Xinmin Zhang, Ding Ding, Jian-Hui Fu, Wei-Dong Zhang, Jun Chen. Neurosci Lett 2004
Yumin Luo, Zhen Qin, Zhen Hong, Xinmin Zhang, Ding Ding, Jian-Hui Fu, Wei-Dong Zhang, Jun Chen. Neurosci Lett 2004
37
Astragaloside IV protects against focal cerebral ischemia/reperfusion injury correlating to suppression of neutrophils adhesion-related molecules.
Min Li, You Z Qu, Zhen W Zhao, Sheng X Wu, Ying Y Liu, Xiao Y Wei, Li Gao, Guo D Gao. Neurochem Int 2012
Min Li, You Z Qu, Zhen W Zhao, Sheng X Wu, Ying Y Liu, Xiao Y Wei, Li Gao, Guo D Gao. Neurochem Int 2012
23
Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro.
Wei-Dong Zhang, Hong Chen, Chuan Zhang, Run-Hui Liu, Hui-Liang Li, Hong-Zhuan Chen. Planta Med 2006
Wei-Dong Zhang, Hong Chen, Chuan Zhang, Run-Hui Liu, Hui-Liang Li, Hong-Zhuan Chen. Planta Med 2006
20
Astragaloside IV reduces cerebral edema post-ischemia/reperfusion correlating the suppression of MMP-9 and AQP4.
Min Li, Rui Na Ma, Li Hong Li, You Zhi Qu, Guo Dong Gao. Eur J Pharmacol 2013
Min Li, Rui Na Ma, Li Hong Li, You Zhi Qu, Guo Dong Gao. Eur J Pharmacol 2013
26
Reversible middle cerebral artery occlusion without craniectomy in rats.
E Z Longa, P R Weinstein, S Carlson, R Cummins. Stroke 1989
E Z Longa, P R Weinstein, S Carlson, R Cummins. Stroke 1989
15
Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression.
Wei-Jian Zhang, Peter Hufnagl, Bernd R Binder, Johann Wojta. Thromb Haemost 2003
Wei-Jian Zhang, Peter Hufnagl, Bernd R Binder, Johann Wojta. Thromb Haemost 2003
14
Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia.
Jiehong Yang, Jinhui Li, Jing Lu, Yuyan Zhang, Zhenhong Zhu, Haitong Wan. J Ethnopharmacol 2012
Jiehong Yang, Jinhui Li, Jing Lu, Yuyan Zhang, Zhenhong Zhu, Haitong Wan. J Ethnopharmacol 2012
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Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.
J B Bederson, L H Pitts, M Tsuji, M C Nishimura, R L Davis, H Bartkowski. Stroke 1986
J B Bederson, L H Pitts, M Tsuji, M C Nishimura, R L Davis, H Bartkowski. Stroke 1986
12
Effects of astragaloside IV on myocardial calcium transport and cardiac function in ischemic rats.
Zi-Pu Li, Qian Cao. Acta Pharmacol Sin 2002
Zi-Pu Li, Qian Cao. Acta Pharmacol Sin 2002
12
Mechanisms underlying vasorelaxant action of astragaloside IV in isolated rat aortic rings.
Chuan Zhang, Xu-Hui Wang, Mei-Fang Zhong, Run-Hui Liu, Hui-Liang Li, Wei-Dong Zhang, Hong Chen. Clin Exp Pharmacol Physiol 2007
Chuan Zhang, Xu-Hui Wang, Mei-Fang Zhong, Run-Hui Liu, Hui-Liang Li, Wei-Dong Zhang, Hong Chen. Clin Exp Pharmacol Physiol 2007
25
Astragaloside IV improves high glucose-induced podocyte adhesion dysfunction via alpha3beta1 integrin upregulation and integrin-linked kinase inhibition.
Jianguo Chen, Dingkun Gui, Yifang Chen, Lijun Mou, Yi Liu, Jianhua Huang. Biochem Pharmacol 2008
Jianguo Chen, Dingkun Gui, Yifang Chen, Lijun Mou, Yi Liu, Jianhua Huang. Biochem Pharmacol 2008
18
Protective effect of astragaloside on focal cerebral ischemia/reperfusion injury in rats.
Yan-Yan Yin, Wei-Ping Li, Hui-Ling Gong, Fen-Fang Zhu, Wei-Zu Li, Guo-Cui Wu. Am J Chin Med 2010
Yan-Yan Yin, Wei-Ping Li, Hui-Ling Gong, Fen-Fang Zhu, Wei-Zu Li, Guo-Cui Wu. Am J Chin Med 2010
20
Astragaloside IV prevents MPP⁺-induced SH-SY5Y cell death via the inhibition of Bax-mediated pathways and ROS production.
Zhi-Guo Zhang, Lin Wu, Ju-Lei Wang, Jian-Dong Yang, Jing Zhang, Jian Zhang, Li-Hong Li, Yi Xia, Li-Bo Yao, Huai-Zhou Qin,[...]. Mol Cell Biochem 2012
Zhi-Guo Zhang, Lin Wu, Ju-Lei Wang, Jian-Dong Yang, Jing Zhang, Jian Zhang, Li-Hong Li, Yi Xia, Li-Bo Yao, Huai-Zhou Qin,[...]. Mol Cell Biochem 2012
13
Neuroprotective effects of Astragaloside IV in 6-hydroxydopamine-treated primary nigral cell culture.
Wing-Sai Chan, Siva Sundara Kumar Durairajan, Jia-Hong Lu, Yan Wang, Li-Xia Xie, Wan-Fung Kum, Irene Koo, Ken Kin Lam Yung, Min Li. Neurochem Int 2009
Wing-Sai Chan, Siva Sundara Kumar Durairajan, Jia-Hong Lu, Yan Wang, Li-Xia Xie, Wan-Fung Kum, Irene Koo, Ken Kin Lam Yung, Min Li. Neurochem Int 2009
10
Astragaloside IV dilates aortic vessels from normal and spontaneously hypertensive rats through endothelium-dependent and endothelium-independent ways.
Wei-Dong Zhang, Chuan Zhang, Xu-Hui Wang, Ping-Jin Gao, Ding-Liang Zhu, Hong Chen, Run-Hui Liu, Hui-Liang Li. Planta Med 2006
Wei-Dong Zhang, Chuan Zhang, Xu-Hui Wang, Ping-Jin Gao, Ding-Liang Zhu, Hong Chen, Run-Hui Liu, Hui-Liang Li. Planta Med 2006
15
Astragaloside IV ameliorates renal injury in streptozotocin-induced diabetic rats through inhibiting NF-κB-mediated inflammatory genes expression.
Dingkun Gui, Jianhua Huang, Yongping Guo, Jianguo Chen, Yifang Chen, Wenzhen Xiao, Xusheng Liu, Niansong Wang. Cytokine 2013
Dingkun Gui, Jianhua Huang, Yongping Guo, Jianguo Chen, Yifang Chen, Wenzhen Xiao, Xusheng Liu, Niansong Wang. Cytokine 2013
9
Astragaloside IV attenuates experimental autoimmune encephalomyelitis of mice by counteracting oxidative stress at multiple levels.
Yixin He, Min Du, Yan Gao, Hongshuai Liu, Hongwei Wang, Xiaojun Wu, Zhengtao Wang. PLoS One 2013
Yixin He, Min Du, Yan Gao, Hongshuai Liu, Hongwei Wang, Xiaojun Wu, Zhengtao Wang. PLoS One 2013
9
Preclinical pharmacokinetics and tissue distribution of a natural cardioprotective agent astragaloside IV in rats and dogs.
Wei-Dong Zhang, Chuan Zhang, Run-Hui Liu, Hui-Liang Li, Jin-Tao Zhang, Chen Mao, Sara Moran, Chun-Lin Chen. Life Sci 2006
Wei-Dong Zhang, Chuan Zhang, Run-Hui Liu, Hui-Liang Li, Jin-Tao Zhang, Chen Mao, Sara Moran, Chun-Lin Chen. Life Sci 2006
9
Astragaloside IV attenuates cognitive impairments induced by transient cerebral ischemia and reperfusion in mice via anti-inflammatory mechanisms.
Min Li, Hongyan Li, Fang Fang, Xueyang Deng, Shiping Ma. Neurosci Lett 2017
Min Li, Hongyan Li, Fang Fang, Xueyang Deng, Shiping Ma. Neurosci Lett 2017
12
Astragaloside IV for Experimental Focal Cerebral Ischemia: Preclinical Evidence and Possible Mechanisms.
Hui-Lin Wang, Qi-Hui Zhou, Meng-Bei Xu, Xiao-Li Zhou, Guo-Qing Zheng. Oxid Med Cell Longev 2017
Hui-Lin Wang, Qi-Hui Zhou, Meng-Bei Xu, Xiao-Li Zhou, Guo-Qing Zheng. Oxid Med Cell Longev 2017
13
The blood-brain barrier/neurovascular unit in health and disease.
Brian T Hawkins, Thomas P Davis. Pharmacol Rev 2005
Brian T Hawkins, Thomas P Davis. Pharmacol Rev 2005
7
Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat.
Yi Yang, Eduardo Y Estrada, Jeffrey F Thompson, Wenlan Liu, Gary A Rosenberg. J Cereb Blood Flow Metab 2007
Yi Yang, Eduardo Y Estrada, Jeffrey F Thompson, Wenlan Liu, Gary A Rosenberg. J Cereb Blood Flow Metab 2007
7
Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia.
Wenlan Liu, Jill Hendren, Xu-Jun Qin, Jiangang Shen, Ke Jian Liu. J Neurochem 2009
Wenlan Liu, Jill Hendren, Xu-Jun Qin, Jiangang Shen, Ke Jian Liu. J Neurochem 2009
7
Protective effects of astragaloside IV on porcine-serum-induced hepatic fibrosis in rats and in vitro effects on hepatic stellate cells.
Hao Liu, Wei Wei, Wu-yi Sun, Xiang Li. J Ethnopharmacol 2009
Hao Liu, Wei Wei, Wu-yi Sun, Xiang Li. J Ethnopharmacol 2009
11
Astragaloside IV attenuates hypoxia-induced cardiomyocyte damage in rats by upregulating superoxide dismutase-1 levels.
Jiong-Yu Hu, Jian Han, Zhi-Gang Chu, Hua-Pei Song, Dong-Xia Zhang, Qiong Zhang, Yue-Sheng Huang. Clin Exp Pharmacol Physiol 2009
Jiong-Yu Hu, Jian Han, Zhi-Gang Chu, Hua-Pei Song, Dong-Xia Zhang, Qiong Zhang, Yue-Sheng Huang. Clin Exp Pharmacol Physiol 2009
12
Astragaloside IV improves homocysteine-induced acute phase endothelial dysfunction via antioxidation.
Li-Hong Qiu, Xian-Ji Xie, Bi-Qi Zhang. Biol Pharm Bull 2010
Li-Hong Qiu, Xian-Ji Xie, Bi-Qi Zhang. Biol Pharm Bull 2010
13
Astragaloside IV improved intracellular calcium handling in hypoxia-reoxygenated cardiomyocytes via the sarcoplasmic reticulum Ca-ATPase.
Xiao-Le Xu, Xiang-Jian Chen, Hui Ji, Ping Li, Yun-Yun Bian, Di Yang, Jin-Dan Xu, Zhi-Ping Bian, Ji-Nan Zhang. Pharmacology 2008
Xiao-Le Xu, Xiang-Jian Chen, Hui Ji, Ping Li, Yun-Yun Bian, Di Yang, Jin-Dan Xu, Zhi-Ping Bian, Ji-Nan Zhang. Pharmacology 2008
10
Chinese herbs: a clinical review of Astragalus, Ligusticum, and Schizandrae.
S Sinclair. Altern Med Rev 1998
S Sinclair. Altern Med Rev 1998
7
Astragaloside IV alleviates early brain injury following experimental subarachnoid hemorrhage in rats.
Anwen Shao, Songxue Guo, Sheng Tu, Al-baadani Ammar, Junjia Tang, Yuan Hong, Haijian Wu, Jianmin Zhang. Int J Med Sci 2014
Anwen Shao, Songxue Guo, Sheng Tu, Al-baadani Ammar, Junjia Tang, Yuan Hong, Haijian Wu, Jianmin Zhang. Int J Med Sci 2014
23
Pharmacological effects of Astragaloside IV: a literature review.
Shuang Ren, Hua Zhang, Yongping Mu, Mingyu Sun, Ping Liu. J Tradit Chin Med 2013
Shuang Ren, Hua Zhang, Yongping Mu, Mingyu Sun, Ping Liu. J Tradit Chin Med 2013
7
The blood-brain barrier: an overview: structure, regulation, and clinical implications.
Praveen Ballabh, Alex Braun, Maiken Nedergaard. Neurobiol Dis 2004
Praveen Ballabh, Alex Braun, Maiken Nedergaard. Neurobiol Dis 2004
6
The complexity of neurobiological processes in acute ischemic stroke.
R Brouns, P P De Deyn. Clin Neurol Neurosurg 2009
R Brouns, P P De Deyn. Clin Neurol Neurosurg 2009
6
Astragaloside IV inhibits spontaneous synaptic transmission and synchronized Ca2+ oscillations on hippocampal neurons.
Shao-qing Zhu, Lei Qi, Yan-fang Rui, Ru-xin Li, Xiang-ping He, Zuo-ping Xie. Acta Pharmacol Sin 2008
Shao-qing Zhu, Lei Qi, Yan-fang Rui, Ru-xin Li, Xiang-ping He, Zuo-ping Xie. Acta Pharmacol Sin 2008
23
Astragaloside IV exerts antiviral effects against coxsackievirus B3 by upregulating interferon-gamma.
Yuanyuan Zhang, Haiyan Zhu, Chenggang Huang, Xiaolan Cui, Yingjie Gao, Yang Huang, Wenfeng Gong, Ye Zhao, Shanshan Guo. J Cardiovasc Pharmacol 2006
Yuanyuan Zhang, Haiyan Zhu, Chenggang Huang, Xiaolan Cui, Yingjie Gao, Yang Huang, Wenfeng Gong, Ye Zhao, Shanshan Guo. J Cardiovasc Pharmacol 2006
11
Effect of astragaloside IV on hepatic glucose-regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin.
Lin Lv, Shao-Yu Wu, Guang-Fa Wang, Jia-Jie Zhang, Jian-Xin Pang, Zhong-Qiu Liu, Wei Xu, Shu-Guang Wu, Jin-Jun Rao. Phytother Res 2010
Lin Lv, Shao-Yu Wu, Guang-Fa Wang, Jia-Jie Zhang, Jian-Xin Pang, Zhong-Qiu Liu, Wei Xu, Shu-Guang Wu, Jin-Jun Rao. Phytother Res 2010
9
Inhibitory effects of astragaloside IV on diabetic peripheral neuropathy in rats.
Junxian Yu, Yindi Zhang, Shi Sun, Jianping Shen, Jun Qiu, Xiaoxing Yin, Honglin Yin, Shaojun Jiang. Can J Physiol Pharmacol 2006
Junxian Yu, Yindi Zhang, Shi Sun, Jianping Shen, Jun Qiu, Xiaoxing Yin, Honglin Yin, Shaojun Jiang. Can J Physiol Pharmacol 2006
7
Inhibitory effects of astragaloside IV on ovalbumin-induced chronic experimental asthma.
Qiang Du, Zhen Chen, Lin-Fu Zhou, Qian Zhang, Mao Huang, Kai-Sheng Yin. Can J Physiol Pharmacol 2008
Qiang Du, Zhen Chen, Lin-Fu Zhou, Qian Zhang, Mao Huang, Kai-Sheng Yin. Can J Physiol Pharmacol 2008
9
Modification of alterations in cardiac function and sarcoplasmic reticulum by astragaloside IV in myocardial injury in vivo.
Xiao-Le Xu, Hui Ji, Shu-Yi Gu, Qin Shao, Qiu-Ju Huang, Yan-Ping Cheng. Eur J Pharmacol 2007
Xiao-Le Xu, Hui Ji, Shu-Yi Gu, Qin Shao, Qiu-Ju Huang, Yan-Ping Cheng. Eur J Pharmacol 2007
11
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.
K J Livak, T D Schmittgen. Methods 2001
K J Livak, T D Schmittgen. Methods 2001
6
Isoflavonoids from Astragalus mongholicus protect PC12 cells from toxicity induced by L-glutamate.
Dehong Yu, Yanlong Duan, Yongming Bao, Chaoliang Wei, Lijia An. J Ethnopharmacol 2005
Dehong Yu, Yanlong Duan, Yongming Bao, Chaoliang Wei, Lijia An. J Ethnopharmacol 2005
6
Astragaloside IV prevents acute kidney injury in two rodent models by inhibiting oxidative stress and apoptosis pathways.
Dingkun Gui, Jianhua Huang, Wei Liu, Yongping Guo, Wenzhen Xiao, Niansong Wang. Apoptosis 2013
Dingkun Gui, Jianhua Huang, Wei Liu, Yongping Guo, Wenzhen Xiao, Niansong Wang. Apoptosis 2013
10
Astragaloside IV, a novel antioxidant, prevents glucose-induced podocyte apoptosis in vitro and in vivo.
Dingkun Gui, Yongping Guo, Feng Wang, Wei Liu, Jianguo Chen, Yifang Chen, Jianhua Huang, Niansong Wang. PLoS One 2012
Dingkun Gui, Yongping Guo, Feng Wang, Wei Liu, Jianguo Chen, Yifang Chen, Jianhua Huang, Niansong Wang. PLoS One 2012
6
Preventive Effects of a Natural Anti-Inflammatory Agent, Astragaloside IV, on Ischemic Acute Kidney Injury in Rats.
Shufeng Tan, Guofu Wang, Yongping Guo, Dingkun Gui, Niansong Wang. Evid Based Complement Alternat Med 2013
Shufeng Tan, Guofu Wang, Yongping Guo, Dingkun Gui, Niansong Wang. Evid Based Complement Alternat Med 2013
20
Astragaloside IV attenuates glycated albumin-induced epithelial-to-mesenchymal transition by inhibiting oxidative stress in renal proximal tubular cells.
Weiwei Qi, Jianying Niu, Qiaojing Qin, Zhongdong Qiao, Yong Gu. Cell Stress Chaperones 2014
Weiwei Qi, Jianying Niu, Qiaojing Qin, Zhongdong Qiao, Yong Gu. Cell Stress Chaperones 2014
14
Astragaloside IV suppresses collagen production of activated hepatic stellate cells via oxidative stress-mediated p38 MAPK pathway.
Xiaoming Li, Xiaoli Wang, Cuiyan Han, Xiaoli Wang, Guihua Xing, Li Zhou, Gang Li, Yingcai Niu. Free Radic Biol Med 2013
Xiaoming Li, Xiaoli Wang, Cuiyan Han, Xiaoli Wang, Guihua Xing, Li Zhou, Gang Li, Yingcai Niu. Free Radic Biol Med 2013
6
EGFR mediates astragaloside IV-induced Nrf2 activation to protect cortical neurons against in vitro ischemia/reperfusion damages.
Da-Min Gu, Pei-Hua Lu, Ke Zhang, Xiang Wang, Min Sun, Guo-Qian Chen, Qiong Wang. Biochem Biophys Res Commun 2015
Da-Min Gu, Pei-Hua Lu, Ke Zhang, Xiang Wang, Min Sun, Guo-Qian Chen, Qiong Wang. Biochem Biophys Res Commun 2015
7
Blood-brain barrier tight junction permeability and ischemic stroke.
Karin E Sandoval, Ken A Witt. Neurobiol Dis 2008
Karin E Sandoval, Ken A Witt. Neurobiol Dis 2008
5
Pathobiology of ischaemic stroke: an integrated view.
U Dirnagl, C Iadecola, M A Moskowitz. Trends Neurosci 1999
U Dirnagl, C Iadecola, M A Moskowitz. Trends Neurosci 1999
5
Effect of astragaloside IV on T, B lymphocyte proliferation and peritoneal macrophage function in mice.
Yan-Ping Wang, Xiao-Yu Li, Chun-Qing Song, Zhi-Bi Hu. Acta Pharmacol Sin 2002
Yan-Ping Wang, Xiao-Yu Li, Chun-Qing Song, Zhi-Bi Hu. Acta Pharmacol Sin 2002
5
Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus.
C Tohda, T Tamura, S Matsuyama, K Komatsu. Br J Pharmacol 2006
C Tohda, T Tamura, S Matsuyama, K Komatsu. Br J Pharmacol 2006
5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.