Gabriele Saretzki. Exp Gerontol 2009
Times Cited: 95
Times Cited: 95
Times Cited
Times Co-cited
Similarity
Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress.
Shaheda Ahmed, João F Passos, Matthew J Birket, Tina Beckmann, Sebastian Brings, Heiko Peters, Mark A Birch-Machin, Thomas von Zglinicki, Gabriele Saretzki. J Cell Sci 2008
Shaheda Ahmed, João F Passos, Matthew J Birket, Tina Beckmann, Sebastian Brings, Heiko Peters, Mark A Birch-Machin, Thomas von Zglinicki, Gabriele Saretzki. J Cell Sci 2008
40
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage.
Judith Haendeler, Stefan Dröse, Nicole Büchner, Sascha Jakob, Joachim Altschmied, Christine Goy, Ioakim Spyridopoulos, Andreas M Zeiher, Ulrich Brandt, Stefanie Dimmeler. Arterioscler Thromb Vasc Biol 2009
Judith Haendeler, Stefan Dröse, Nicole Büchner, Sascha Jakob, Joachim Altschmied, Christine Goy, Ioakim Spyridopoulos, Andreas M Zeiher, Ulrich Brandt, Stefanie Dimmeler. Arterioscler Thromb Vasc Biol 2009
28
Telomere dysfunction induces metabolic and mitochondrial compromise.
Ergün Sahin, Simona Colla, Marc Liesa, Javid Moslehi, Florian L Müller, Mira Guo, Marcus Cooper, Darrell Kotton, Attila J Fabian, Carl Walkey,[...]. Nature 2011
Ergün Sahin, Simona Colla, Marc Liesa, Javid Moslehi, Florian L Müller, Mira Guo, Marcus Cooper, Darrell Kotton, Attila J Fabian, Carl Walkey,[...]. Nature 2011
21
Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis.
Janine Hertzog Santos, Joel N Meyer, Bennett Van Houten. Hum Mol Genet 2006
Janine Hertzog Santos, Joel N Meyer, Bennett Van Houten. Hum Mol Genet 2006
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Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage.
Janine Hertzog Santos, Joel N Meyer, Milan Skorvaga, Lois A Annab, Bennett Van Houten. Aging Cell 2004
Janine Hertzog Santos, Joel N Meyer, Milan Skorvaga, Lois A Annab, Bennett Van Houten. Aging Cell 2004
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Accelerated telomere shortening in response to life stress.
Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Firdaus S Dhabhar, Nancy E Adler, Jason D Morrow, Richard M Cawthon. Proc Natl Acad Sci U S A 2004
Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Firdaus S Dhabhar, Nancy E Adler, Jason D Morrow, Richard M Cawthon. Proc Natl Acad Sci U S A 2004
14
Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
13
Association between telomere length in blood and mortality in people aged 60 years or older.
Richard M Cawthon, Ken R Smith, Elizabeth O'Brien, Anna Sivatchenko, Richard A Kerber. Lancet 2003
Richard M Cawthon, Ken R Smith, Elizabeth O'Brien, Anna Sivatchenko, Richard A Kerber. Lancet 2003
12
Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria.
Nilesh K Sharma, Aurelio Reyes, Paula Green, Matthieu J Caron, Marcelo G Bonini, Donna M Gordon, Ian J Holt, Janine Hertzog Santos. Nucleic Acids Res 2012
Nilesh K Sharma, Aurelio Reyes, Paula Green, Matthieu J Caron, Marcelo G Bonini, Donna M Gordon, Ian J Holt, Janine Hertzog Santos. Nucleic Acids Res 2012
12
Telomerase modulates Wnt signalling by association with target gene chromatin.
Jae-Il Park, Andrew S Venteicher, Ji Yeon Hong, Jinkuk Choi, Sohee Jun, Marina Shkreli, Woody Chang, Zhaojing Meng, Peggie Cheung, Hong Ji,[...]. Nature 2009
Jae-Il Park, Andrew S Venteicher, Ji Yeon Hong, Jinkuk Choi, Sohee Jun, Marina Shkreli, Woody Chang, Zhaojing Meng, Peggie Cheung, Hong Ji,[...]. Nature 2009
11
An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA.
Yoshiko Maida, Mami Yasukawa, Miho Furuuchi, Timo Lassmann, Richard Possemato, Naoko Okamoto, Vivi Kasim, Yoshihide Hayashizaki, William C Hahn, Kenkichi Masutomi. Nature 2009
Yoshiko Maida, Mami Yasukawa, Miho Furuuchi, Timo Lassmann, Richard Possemato, Naoko Okamoto, Vivi Kasim, Yoshihide Hayashizaki, William C Hahn, Kenkichi Masutomi. Nature 2009
11
Obesity, cigarette smoking, and telomere length in women.
A M Valdes, T Andrew, J P Gardner, M Kimura, E Oelsner, L F Cherkas, A Aviv, T D Spector. Lancet 2005
A M Valdes, T Andrew, J P Gardner, M Kimura, E Oelsner, L F Cherkas, A Aviv, T D Spector. Lancet 2005
10
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.
Kenkichi Masutomi, Richard Possemato, Judy M Y Wong, Jennifer L Currier, Zuzana Tothova, Judith B Manola, Shridar Ganesan, Peter M Lansdorp, Kathleen Collins, William C Hahn. Proc Natl Acad Sci U S A 2005
Kenkichi Masutomi, Richard Possemato, Judy M Y Wong, Jennifer L Currier, Zuzana Tothova, Judith B Manola, Shridar Ganesan, Peter M Lansdorp, Kathleen Collins, William C Hahn. Proc Natl Acad Sci U S A 2005
10
Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.
Judith Haendeler, Jörg Hoffmann, Ralf P Brandes, Andreas M Zeiher, Stefanie Dimmeler. Mol Cell Biol 2003
Judith Haendeler, Jörg Hoffmann, Ralf P Brandes, Andreas M Zeiher, Stefanie Dimmeler. Mol Cell Biol 2003
10
Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
10
hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells.
Inthrani R Indran, Manoor P Hande, Shazib Pervaiz. Cancer Res 2011
Inthrani R Indran, Manoor P Hande, Shazib Pervaiz. Cancer Res 2011
10
Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells.
Judith Haendeler, Jörg Hoffmann, J Florian Diehl, Mariuca Vasa, Ioakim Spyridopoulos, Andreas M Zeiher, Stefanie Dimmeler. Circ Res 2004
Judith Haendeler, Jörg Hoffmann, J Florian Diehl, Mariuca Vasa, Ioakim Spyridopoulos, Andreas M Zeiher, Stefanie Dimmeler. Circ Res 2004
9
Dynamics of telomerase activity in response to acute psychological stress.
Elissa S Epel, Jue Lin, Firdaus S Dhabhar, Owen M Wolkowitz, E Puterman, Lori Karan, Elizabeth H Blackburn. Brain Behav Immun 2010
Elissa S Epel, Jue Lin, Firdaus S Dhabhar, Owen M Wolkowitz, E Puterman, Lori Karan, Elizabeth H Blackburn. Brain Behav Immun 2010
9
Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity.
Hyo Jung Kang, Yoon Sik Choi, Seung-Beom Hong, Kee-Won Kim, Ran-Sook Woo, Seok Joon Won, Eun Ju Kim, Hee Kyung Jeon, So-Young Jo, Tae Kook Kim,[...]. J Neurosci 2004
Hyo Jung Kang, Yoon Sik Choi, Seung-Beom Hong, Kee-Won Kim, Ran-Sook Woo, Seok Joon Won, Eun Ju Kim, Hee Kyung Jeon, So-Young Jo, Tae Kook Kim,[...]. J Neurosci 2004
9
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.
Mariela Jaskelioff, Florian L Muller, Ji-Hye Paik, Emily Thomas, Shan Jiang, Andrew C Adams, Ergun Sahin, Maria Kost-Alimova, Alexei Protopopov, Juan Cadiñanos,[...]. Nature 2011
Mariela Jaskelioff, Florian L Muller, Ji-Hye Paik, Emily Thomas, Shan Jiang, Andrew C Adams, Ergun Sahin, Maria Kost-Alimova, Alexei Protopopov, Juan Cadiñanos,[...]. Nature 2011
9
Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins.
Paula Martínez, María A Blasco. Nat Rev Cancer 2011
Paula Martínez, María A Blasco. Nat Rev Cancer 2011
9
Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients.
Amanda K Damjanovic, Yinhua Yang, Ronald Glaser, Janice K Kiecolt-Glaser, Huy Nguyen, Bryon Laskowski, Yixiao Zou, David Q Beversdorf, Nan-ping Weng. J Immunol 2007
Amanda K Damjanovic, Yinhua Yang, Ronald Glaser, Janice K Kiecolt-Glaser, Huy Nguyen, Bryon Laskowski, Yixiao Zou, David Q Beversdorf, Nan-ping Weng. J Immunol 2007
8
Increased telomerase activity and comprehensive lifestyle changes: a pilot study.
Dean Ornish, Jue Lin, Jennifer Daubenmier, Gerdi Weidner, Elissa Epel, Colleen Kemp, Mark Jesus M Magbanua, Ruth Marlin, Loren Yglecias, Peter R Carroll,[...]. Lancet Oncol 2008
Dean Ornish, Jue Lin, Jennifer Daubenmier, Gerdi Weidner, Elissa Epel, Colleen Kemp, Mark Jesus M Magbanua, Ruth Marlin, Loren Yglecias, Peter R Carroll,[...]. Lancet Oncol 2008
8
Involvement of hTERT in apoptosis induced by interference with Bcl-2 expression and function.
D Del Bufalo, A Rizzo, D Trisciuoglio, G Cardinali, M R Torrisi, U Zangemeister-Wittke, G Zupi, A Biroccio. Cell Death Differ 2005
D Del Bufalo, A Rizzo, D Trisciuoglio, G Cardinali, M R Torrisi, U Zangemeister-Wittke, G Zupi, A Biroccio. Cell Death Differ 2005
8
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation.
Laura L Smith, Hilary A Coller, James M Roberts. Nat Cell Biol 2003
Laura L Smith, Hilary A Coller, James M Roberts. Nat Cell Biol 2003
8
TERT promotes cellular and organismal survival independently of telomerase activity.
J Lee, Y H Sung, C Cheong, Y S Choi, H K Jeon, W Sun, W C Hahn, F Ishikawa, H-W Lee. Oncogene 2008
J Lee, Y H Sung, C Cheong, Y S Choi, H K Jeon, W Sun, W C Hahn, F Ishikawa, H-W Lee. Oncogene 2008
8
hTERT associates with human telomeres and enhances genomic stability and DNA repair.
Girdhar G Sharma, Arun Gupta, Huichen Wang, Harry Scherthan, Sonu Dhar, Varsha Gandhi, George Iliakis, Jerry W Shay, Charles S H Young, Tej K Pandita. Oncogene 2003
Girdhar G Sharma, Arun Gupta, Huichen Wang, Harry Scherthan, Sonu Dhar, Varsha Gandhi, George Iliakis, Jerry W Shay, Charles S H Young, Tej K Pandita. Oncogene 2003
8
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis.
Chatchawan Singhapol, Deepali Pal, Rafal Czapiewski, Mahendar Porika, Glyn Nelson, Gabriele C Saretzki. PLoS One 2013
Chatchawan Singhapol, Deepali Pal, Rafal Czapiewski, Mahendar Porika, Glyn Nelson, Gabriele C Saretzki. PLoS One 2013
8
Extra-telomeric functions of human telomerase: cancer, mitochondria and oxidative stress.
G Saretzki. Curr Pharm Des 2014
G Saretzki. Curr Pharm Des 2014
9
12
Reduced telomerase activity in human T lymphocytes exposed to cortisol.
Jenny Choi, Steven R Fauce, Rita B Effros. Brain Behav Immun 2008
Jenny Choi, Steven R Fauce, Rita B Effros. Brain Behav Immun 2008
7
Telomere shortening in atherosclerosis.
N J Samani, R Boultby, R Butler, J R Thompson, A H Goodall. Lancet 2001
N J Samani, R Boultby, R Butler, J R Thompson, A H Goodall. Lancet 2001
7
Rise in insulin resistance is associated with escalated telomere attrition.
Jeffrey P Gardner, Shengxu Li, Sathanur R Srinivasan, Wei Chen, Masayuki Kimura, Xiaobin Lu, Gerald S Berenson, Abraham Aviv. Circulation 2005
Jeffrey P Gardner, Shengxu Li, Sathanur R Srinivasan, Wei Chen, Masayuki Kimura, Xiaobin Lu, Gerald S Berenson, Abraham Aviv. Circulation 2005
7
Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance.
Jue Lin, Elissa Epel, Joshua Cheon, Candyce Kroenke, Elizabeth Sinclair, Marty Bigos, Owen Wolkowitz, Synthia Mellon, Elizabeth Blackburn. J Immunol Methods 2010
Jue Lin, Elissa Epel, Joshua Cheon, Candyce Kroenke, Elizabeth Sinclair, Marty Bigos, Owen Wolkowitz, Synthia Mellon, Elizabeth Blackburn. J Immunol Methods 2010
7
A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction.
Olga A Kovalenko, Matthieu J Caron, Perihan Ulema, Carolina Medrano, Andrew P Thomas, Masayuki Kimura, Marcelo G Bonini, Utz Herbig, Janine H Santos. Aging Cell 2010
Olga A Kovalenko, Matthieu J Caron, Perihan Ulema, Carolina Medrano, Andrew P Thomas, Masayuki Kimura, Marcelo G Bonini, Utz Herbig, Janine H Santos. Aging Cell 2010
11
Telomerase maintains telomere structure in normal human cells.
Kenkichi Masutomi, Evan Y Yu, Shilagardy Khurts, Ittai Ben-Porath, Jennifer L Currier, Geoffrey B Metz, Mary W Brooks, Shuichi Kaneko, Seishi Murakami, James A DeCaprio,[...]. Cell 2003
Kenkichi Masutomi, Evan Y Yu, Shilagardy Khurts, Ittai Ben-Porath, Jennifer L Currier, Geoffrey B Metz, Mary W Brooks, Shuichi Kaneko, Seishi Murakami, James A DeCaprio,[...]. Cell 2003
7
Cell aging in relation to stress arousal and cardiovascular disease risk factors.
Elissa S Epel, Jue Lin, Frank H Wilhelm, Owen M Wolkowitz, Richard Cawthon, Nancy E Adler, Christyn Dolbier, Wendy B Mendes, Elizabeth H Blackburn. Psychoneuroendocrinology 2006
Elissa S Epel, Jue Lin, Frank H Wilhelm, Owen M Wolkowitz, Richard Cawthon, Nancy E Adler, Christyn Dolbier, Wendy B Mendes, Elizabeth H Blackburn. Psychoneuroendocrinology 2006
7
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability.
M T Hemann, M A Strong, L Y Hao, C W Greider. Cell 2001
M T Hemann, M A Strong, L Y Hao, C W Greider. Cell 2001
7
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer.
Bruno Bernardes de Jesus, Elsa Vera, Kerstin Schneeberger, Agueda M Tejera, Eduard Ayuso, Fatima Bosch, Maria A Blasco. EMBO Mol Med 2012
Bruno Bernardes de Jesus, Elsa Vera, Kerstin Schneeberger, Agueda M Tejera, Eduard Ayuso, Fatima Bosch, Maria A Blasco. EMBO Mol Med 2012
7
7
Cutting edge: telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTERT phosphorylation and nuclear translocation.
K Liu, R J Hodes, Weng Np. J Immunol 2001
K Liu, R J Hodes, Weng Np. J Immunol 2001
6
Monocyte telomere shortening and oxidative DNA damage in type 2 diabetes.
Mike J Sampson, Mark S Winterbone, Jackie C Hughes, Nicoletta Dozio, David A Hughes. Diabetes Care 2006
Mike J Sampson, Mark S Winterbone, Jackie C Hughes, Nicoletta Dozio, David A Hughes. Diabetes Care 2006
6
Telomere length and mortality: a study of leukocytes in elderly Danish twins.
Masayuki Kimura, Jacob V B Hjelmborg, Jeffrey P Gardner, Lise Bathum, Michael Brimacombe, Xiaobin Lu, Lene Christiansen, James W Vaupel, Abraham Aviv, Kaare Christensen. Am J Epidemiol 2008
Masayuki Kimura, Jacob V B Hjelmborg, Jeffrey P Gardner, Lise Bathum, Michael Brimacombe, Xiaobin Lu, Lene Christiansen, James W Vaupel, Abraham Aviv, Kaare Christensen. Am J Epidemiol 2008
6
Linking functional decline of telomeres, mitochondria and stem cells during ageing.
Ergün Sahin, Ronald A Depinho. Nature 2010
Ergün Sahin, Ronald A Depinho. Nature 2010
6
6
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