A citation-based method for searching scientific literature

Kenneth P Olive, Michael A Jacobetz, Christian J Davidson, Aarthi Gopinathan, Dominick McIntyre, Davina Honess, Basetti Madhu, Mae A Goldgraben, Meredith E Caldwell, David Allard, Kristopher K Frese, Gina Denicola, Christine Feig, Chelsea Combs, Stephen P Winter, Heather Ireland-Zecchini, Stefanie Reichelt, William J Howat, Alex Chang, Mousumi Dhara, Lifu Wang, Felix Rückert, Robert Grützmann, Christian Pilarsky, Kamel Izeradjene, Sunil R Hingorani, Pearl Huang, Susan E Davies, William Plunkett, Merrill Egorin, Ralph H Hruban, Nigel Whitebread, Karen McGovern, Julian Adams, Christine Iacobuzio-Donahue, John Griffiths, David A Tuveson. Science 2009
Times Cited: 2169







List of co-cited articles
1109 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma.
Paolo P Provenzano, Carlos Cuevas, Amy E Chang, Vikas K Goel, Daniel D Von Hoff, Sunil R Hingorani. Cancer Cell 2012
34

Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.
Berna C Özdemir, Tsvetelina Pentcheva-Hoang, Julienne L Carstens, Xiaofeng Zheng, Chia-Chin Wu, Tyler R Simpson, Hanane Laklai, Hikaru Sugimoto, Christoph Kahlert, Sergey V Novitskiy,[...]. Cancer Cell 2014
33

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.
Andrew D Rhim, Paul E Oberstein, Dafydd H Thomas, Emily T Mirek, Carmine F Palermo, Stephen A Sastra, Erin N Dekleva, Tyler Saunders, Claudia P Becerra, Ian W Tattersall,[...]. Cancer Cell 2014
29

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.
Daniel Öhlund, Abram Handly-Santana, Giulia Biffi, Ela Elyada, Ana S Almeida, Mariano Ponz-Sarvise, Vincenzo Corbo, Tobiloba E Oni, Stephen A Hearn, Eun Jung Lee,[...]. J Exp Med 2017
821
27

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts.
Ela Elyada, Mohan Bolisetty, Pasquale Laise, William F Flynn, Elise T Courtois, Richard A Burkhart, Jonathan A Teinor, Pascal Belleau, Giulia Biffi, Matthew S Lucito,[...]. Cancer Discov 2019
404
21

IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma.
Giulia Biffi, Tobiloba E Oni, Benjamin Spielman, Yuan Hao, Ela Elyada, Youngkyu Park, Jonathan Preall, David A Tuveson. Cancer Discov 2019
359
20

Cancer statistics, 2020.
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2020
19

A framework for advancing our understanding of cancer-associated fibroblasts.
Erik Sahai, Igor Astsaturov, Edna Cukierman, David G DeNardo, Mikala Egeblad, Ronald M Evans, Douglas Fearon, Florian R Greten, Sunil R Hingorani, Tony Hunter,[...]. Nat Rev Cancer 2020
699
19

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.
Mara H Sherman, Ruth T Yu, Dannielle D Engle, Ning Ding, Annette R Atkins, Herve Tiriac, Eric A Collisson, Frances Connor, Terry Van Dyke, Serguei Kozlov,[...]. Cell 2014
588
19

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.
Christine Feig, James O Jones, Matthew Kraman, Richard J B Wells, Andrew Deonarine, Derek S Chan, Claire M Connell, Edward W Roberts, Qi Zhao, Otavia L Caballero,[...]. Proc Natl Acad Sci U S A 2013
958
18


Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice.
Sunil R Hingorani, Lifu Wang, Asha S Multani, Chelsea Combs, Therese B Deramaudt, Ralph H Hruban, Anil K Rustgi, Sandy Chang, David A Tuveson. Cancer Cell 2005
16

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.
Michael A Jacobetz, Derek S Chan, Albrecht Neesse, Tashinga E Bapiro, Natalie Cook, Kristopher K Frese, Christine Feig, Tomoaki Nakagawa, Meredith E Caldwell, Heather I Zecchini,[...]. Gut 2013
626
15

Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer.
Daniel V T Catenacci, Melissa R Junttila, Theodore Karrison, Nathan Bahary, Margit N Horiba, Sreenivasa R Nattam, Robert Marsh, James Wallace, Mark Kozloff, Lakshmi Rajdev,[...]. J Clin Oncol 2015
288
14

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.
Richard A Moffitt, Raoud Marayati, Elizabeth L Flate, Keith E Volmar, S Gabriela Herrera Loeza, Katherine A Hoadley, Naim U Rashid, Lindsay A Williams, Samuel C Eaton, Alexander H Chung,[...]. Nat Genet 2015
816
12

A Phase I Study of FOLFIRINOX Plus IPI-926, a Hedgehog Pathway Inhibitor, for Advanced Pancreatic Adenocarcinoma.
Andrew H Ko, Noelle LoConte, Margaret A Tempero, Evan J Walker, R Kate Kelley, Stephanie Lewis, Wei-Chou Chang, Emily Kantoff, Michael W Vannier, Daniel V Catenacci,[...]. Pancreas 2016
122
12

Stromal response to Hedgehog signaling restrains pancreatic cancer progression.
John J Lee, Rushika M Perera, Huaijun Wang, Dai-Chen Wu, X Shawn Liu, Shiwei Han, Julien Fitamant, Phillip D Jones, Krishna S Ghanta, Sally Kawano,[...]. Proc Natl Acad Sci U S A 2014
305
12

Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma.
Ana De Jesus-Acosta, Elizabeth A Sugar, Peter J O'Dwyer, Ramesh K Ramanathan, Daniel D Von Hoff, Zeshaan Rasheed, Lei Zheng, Asma Begum, Robert Anders, Anirban Maitra,[...]. Br J Cancer 2020
52
21

FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer.
Thierry Conroy, Pascal Hammel, Mohamed Hebbar, Meher Ben Abdelghani, Alice C Wei, Jean-Luc Raoul, Laurence Choné, Eric Francois, Pascal Artru, James J Biagi,[...]. N Engl J Med 2018
955
11

Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy.
Claudia X Dominguez, Sören Müller, Shilpa Keerthivasan, Hartmut Koeppen, Jeffrey Hung, Sarah Gierke, Beatrice Breart, Oded Foreman, Travis W Bainbridge, Alessandra Castiglioni,[...]. Cancer Discov 2020
158
11

The pancreas cancer microenvironment.
Christine Feig, Aarthi Gopinathan, Albrecht Neesse, Derek S Chan, Natalie Cook, David A Tuveson. Clin Cancer Res 2012
789
11

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine.
Daniel D Von Hoff, Thomas Ervin, Francis P Arena, E Gabriela Chiorean, Jeffrey Infante, Malcolm Moore, Thomas Seay, Sergei A Tjulandin, Wen Wee Ma, Mansoor N Saleh,[...]. N Engl J Med 2013
10

Genomic analyses identify molecular subtypes of pancreatic cancer.
Peter Bailey, David K Chang, Katia Nones, Amber L Johns, Ann-Marie Patch, Marie-Claude Gingras, David K Miller, Angelika N Christ, Tim J C Bruxner, Michael C Quinn,[...]. Nature 2016
10

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer.
Thierry Conroy, Françoise Desseigne, Marc Ychou, Olivier Bouché, Rosine Guimbaud, Yves Bécouarn, Antoine Adenis, Jean-Luc Raoul, Sophie Gourgou-Bourgade, Christelle de la Fouchardière,[...]. N Engl J Med 2011
10

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.
Yu Shi, Weina Gao, Nikki K Lytle, Peiwu Huang, Xiao Yuan, Amanda M Dann, Maya Ridinger-Saison, Kathleen E DelGiorno, Corina E Antal, Gaoyang Liang,[...]. Nature 2019
138
10

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.
H A Burris, M J Moore, J Andersen, M R Green, M L Rothenberg, M R Modiano, M C Cripps, R K Portenoy, A M Storniolo, P Tarassoff,[...]. J Clin Oncol 1997
10

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels.
Vikash P Chauhan, John D Martin, Hao Liu, Delphine A Lacorre, Saloni R Jain, Sergey V Kozin, Triantafyllos Stylianopoulos, Ahmed S Mousa, Xiaoxing Han, Pichet Adstamongkonkul,[...]. Nat Commun 2013
500
10

HALO 202: Randomized Phase II Study of PEGPH20 Plus Nab-Paclitaxel/Gemcitabine Versus Nab-Paclitaxel/Gemcitabine in Patients With Untreated, Metastatic Pancreatic Ductal Adenocarcinoma.
Sunil R Hingorani, Lei Zheng, Andrea J Bullock, Tara E Seery, William P Harris, Darren S Sigal, Fadi Braiteh, Paul S Ritch, Mark M Zalupski, Nathan Bahary,[...]. J Clin Oncol 2018
226
10

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.
Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying,[...]. Nature 2016
529
9

Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer.
Clifford J Whatcott, Caroline H Diep, Ping Jiang, Aprill Watanabe, Janine LoBello, Chao Sima, Galen Hostetter, H Michael Shepard, Daniel D Von Hoff, Haiyong Han. Clin Cancer Res 2015
302
9

Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy.
Hong Jiang, Samarth Hegde, Brett L Knolhoff, Yu Zhu, John M Herndon, Melissa A Meyer, Timothy M Nywening, William G Hawkins, Irina M Shapiro, David T Weaver,[...]. Nat Med 2016
479
9

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
9

Pilot clinical trial of hedgehog pathway inhibitor GDC-0449 (vismodegib) in combination with gemcitabine in patients with metastatic pancreatic adenocarcinoma.
Edward J Kim, Vaibhav Sahai, Ethan V Abel, Kent A Griffith, Joel K Greenson, Naoko Takebe, Gazala N Khan, John L Blau, Ronald Craig, Ulysses G Balis,[...]. Clin Cancer Res 2014
168
9

CAF Subpopulations: A New Reservoir of Stromal Targets in Pancreatic Cancer.
Brooke A Pereira, Claire Vennin, Michael Papanicolaou, Cecilia R Chambers, David Herrmann, Jennifer P Morton, Thomas R Cox, Paul Timpson. Trends Cancer 2019
93
9

Randomized Phase III Trial of Pegvorhyaluronidase Alfa With Nab-Paclitaxel Plus Gemcitabine for Patients With Hyaluronan-High Metastatic Pancreatic Adenocarcinoma.
Eric Van Cutsem, Margaret A Tempero, Darren Sigal, Do-Youn Oh, Nicola Fazio, Teresa Macarulla, Erika Hitre, Pascal Hammel, Andrew E Hendifar, Susan E Bates,[...]. J Clin Oncol 2020
81
11

Pancreatic cancer.
Jonathan D Mizrahi, Rishi Surana, Juan W Valle, Rachna T Shroff. Lancet 2020
384
9

Fibroblast Heterogeneity in the Pancreatic Tumor Microenvironment.
Erin Helms, M Kathrina Onate, Mara H Sherman. Cancer Discov 2020
85
10

Inter- and intra-tumoural heterogeneity in cancer-associated fibroblasts of human pancreatic ductal adenocarcinoma.
Cindy Neuzillet, Annemilaï Tijeras-Raballand, Chanthirika Ragulan, Jérôme Cros, Yatish Patil, Matthieu Martinet, Mert Erkan, Jörg Kleeff, Jeremy Wilson, Minoti Apte,[...]. J Pathol 2019
107
9

Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States.
Lola Rahib, Benjamin D Smith, Rhonda Aizenberg, Allison B Rosenzweig, Julie M Fleshman, Lynn M Matrisian. Cancer Res 2014
8

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy.
Eric A Collisson, Anguraj Sadanandam, Peter Olson, William J Gibb, Morgan Truitt, Shenda Gu, Janine Cooc, Jennifer Weinkle, Grace E Kim, Lakshmi Jakkula,[...]. Nat Med 2011
899
8

Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells.
M V Apte, S Park, P A Phillips, N Santucci, D Goldstein, R K Kumar, G A Ramm, M Buchler, H Friess, J A McCarroll,[...]. Pancreas 2004
410
8

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
8

Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells.
Max G Bachem, Marion Schünemann, Marco Ramadani, Marco Siech, Hans Beger, Andreas Buck, Shaoxia Zhou, Alexandra Schmid-Kotsas, Guido Adler. Gastroenterology 2005
452
8

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Hanane Laklai, Yekaterina A Miroshnikova, Michael W Pickup, Eric A Collisson, Grace E Kim, Alex S Barrett, Ryan C Hill, Johnathon N Lakins, David D Schlaepfer, Janna K Mouw,[...]. Nat Med 2016
305
8

Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake.
Markus Loeffler, Jörg A Krüger, Andreas G Niethammer, Ralph A Reisfeld. J Clin Invest 2006
398
8

Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha.
Matthew Kraman, Paul J Bambrough, James N Arnold, Edward W Roberts, Lukasz Magiera, James O Jones, Aarthi Gopinathan, David A Tuveson, Douglas T Fearon. Science 2010
690
8

Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial.
Janet E Murphy, Jennifer Y Wo, David P Ryan, Jeffrey W Clark, Wenqing Jiang, Beow Y Yeap, Lorraine C Drapek, Leilana Ly, Christian V Baglini, Lawrence S Blaszkowsky,[...]. JAMA Oncol 2019
190
8

Diversity and Biology of Cancer-Associated Fibroblasts.
Giulia Biffi, David A Tuveson. Physiol Rev 2021
80
10

CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness.
Shicheng Su, Jianing Chen, Herui Yao, Jiang Liu, Shubin Yu, Liyan Lao, Minghui Wang, Manli Luo, Yue Xing, Fei Chen,[...]. Cell 2018
462
8

Whole genomes redefine the mutational landscape of pancreatic cancer.
Nicola Waddell, Marina Pajic, Ann-Marie Patch, David K Chang, Karin S Kassahn, Peter Bailey, Amber L Johns, David Miller, Katia Nones, Kelly Quek,[...]. Nature 2015
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.