A citation-based method for searching scientific literature

Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
Times Cited: 7832







List of co-cited articles
368 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
23

On the origin of cancer cells.
O WARBURG. Science 1956
19

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.
Ralph J DeBerardinis, Julian J Lum, Georgia Hatzivassiliou, Craig B Thompson. Cell Metab 2008
12

THE METABOLISM OF TUMORS IN THE BODY.
O Warburg, F Wind, E Negelein. J Gen Physiol 1927
11

The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
11

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
10

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
9

Regulation of cancer cell metabolism.
Rob A Cairns, Isaac S Harris, Tak W Mak. Nat Rev Cancer 2011
8

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.
Heather R Christofk, Matthew G Vander Heiden, Marian H Harris, Arvind Ramanathan, Robert E Gerszten, Ru Wei, Mark D Fleming, Stuart L Schreiber, Lewis C Cantley. Nature 2008
8

Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
7

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
7


Why do cancers have high aerobic glycolysis?
Robert A Gatenby, Robert J Gillies. Nat Rev Cancer 2004
6


Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
948
5

Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Matt I Gross, Susan D Demo, Jennifer B Dennison, Lijing Chen, Tania Chernov-Rogan, Bindu Goyal, Julie R Janes, Guy J Laidig, Evan R Lewis, Jim Li,[...]. Mol Cancer Ther 2014
471
4

From Krebs to clinic: glutamine metabolism to cancer therapy.
Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
614
4


The multifaceted roles of fatty acid synthesis in cancer.
Florian Röhrig, Almut Schulze. Nat Rev Cancer 2016
416
4

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1.
Weibo Luo, Hongxia Hu, Ryan Chang, Jun Zhong, Matthew Knabel, Robert O'Meally, Robert N Cole, Akhilesh Pandey, Gregg L Semenza. Cell 2011
791
4

Akt stimulates aerobic glycolysis in cancer cells.
Rebecca L Elstrom, Daniel E Bauer, Monica Buzzai, Robyn Karnauskas, Marian H Harris, David R Plas, Hongming Zhuang, Ryan M Cinalli, Abass Alavi, Charles M Rudin,[...]. Cancer Res 2004
978
4

Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches.
Karen G de la Cruz-López, Leonardo Josué Castro-Muñoz, Diego O Reyes-Hernández, Alejandro García-Carrancá, Joaquín Manzo-Merino. Front Oncol 2019
107
4

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.
Pierre Sonveaux, Frédérique Végran, Thies Schroeder, Melanie C Wergin, Julien Verrax, Zahid N Rabbani, Christophe J De Saedeleer, Kelly M Kennedy, Caroline Diepart, Bénédicte F Jordan,[...]. J Clin Invest 2008
998
4

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion.
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen,[...]. Science 2019
166
3

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
3

Glucose metabolism in pig outer retina in light and darkness.
L Wang, P Törnquist, A Bill. Acta Physiol Scand 1997
88
3

Glucose metabolism of the inner retina in pigs in darkness and light.
L Wang, P Törnquist, A Bill. Acta Physiol Scand 1997
81
3

Glycolytic reliance promotes anabolism in photoreceptors.
Yashodhan Chinchore, Tedi Begaj, David Wu, Eugene Drokhlyansky, Constance L Cepko. Elife 2017
66
4

Pyruvate kinase and aspartate-glutamate carrier distributions reveal key metabolic links between neurons and glia in retina.
Ken J Lindsay, Jianhai Du, Stephanie R Sloat, Laura Contreras, Jonathan D Linton, Sally J Turner, Martin Sadilek, Jorgina Satrústegui, James B Hurley. Proc Natl Acad Sci U S A 2014
70
4

ATP consumption by mammalian rod photoreceptors in darkness and in light.
Haruhisa Okawa, Alapakkam P Sampath, Simon B Laughlin, Gordon L Fain. Curr Biol 2008
182
3

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.
Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying,[...]. Nature 2016
450
3

Targeting Autophagy in Cancer: Recent Advances and Future Directions.
Ravi K Amaravadi, Alec C Kimmelman, Jayanta Debnath. Cancer Discov 2019
158
3

Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.
Lei Lv, Dong Li, Di Zhao, Ruiting Lin, Yajing Chu, Heng Zhang, Zhengyu Zha, Ying Liu, Zi Li, Yanping Xu,[...]. Mol Cell 2011
357
3


Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation.
Weiwei Yang, Yan Xia, Haitao Ji, Yanhua Zheng, Ji Liang, Wenhua Huang, Xiang Gao, Kenneth Aldape, Zhimin Lu. Nature 2011
601
3

Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase.
Xueliang Gao, Haizhen Wang, Jenny J Yang, Xiaowei Liu, Zhi-Ren Liu. Mol Cell 2012
439
3

Pyruvate kinase: Function, regulation and role in cancer.
William J Israelsen, Matthew G Vander Heiden. Semin Cell Dev Biol 2015
192
3

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses.
Dimitrios Anastasiou, George Poulogiannis, John M Asara, Matthew B Boxer, Jian-kang Jiang, Min Shen, Gary Bellinger, Atsuo T Sasaki, Jason W Locasale, Douglas S Auld,[...]. Science 2011
686
3

Oxygen availability and metabolic adaptations.
Michael S Nakazawa, Brian Keith, M Celeste Simon. Nat Rev Cancer 2016
158
3

Targeting hypoxia in cancer therapy.
William R Wilson, Michael P Hay. Nat Rev Cancer 2011
3

Tumour acidosis: from the passenger to the driver's seat.
Cyril Corbet, Olivier Feron. Nat Rev Cancer 2017
280
3


The pentose phosphate pathway and cancer.
Krushna C Patra, Nissim Hay. Trends Biochem Sci 2014
516
3

Targeting Metabolism for Cancer Therapy.
Alba Luengo, Dan Y Gui, Matthew G Vander Heiden. Cell Chem Biol 2017
287
3

Tumor glycolysis as a target for cancer therapy: progress and prospects.
Shanmugasundaram Ganapathy-Kanniappan, Jean-Francois H Geschwind. Mol Cancer 2013
379
3

Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR.
Jan H Ardenkjaer-Larsen, Björn Fridlund, Andreas Gram, Georg Hansson, Lennart Hansson, Mathilde H Lerche, Rolf Servin, Mikkel Thaning, Klaes Golman. Proc Natl Acad Sci U S A 2003
3

Inhibitory effect of tumor cell-derived lactic acid on human T cells.
Karin Fischer, Petra Hoffmann, Simon Voelkl, Norbert Meidenbauer, Julia Ammer, Matthias Edinger, Eva Gottfried, Sabine Schwarz, Gregor Rothe, Sabine Hoves,[...]. Blood 2007
793
3

Regulation of the pentose phosphate pathway in cancer.
Peng Jiang, Wenjing Du, Mian Wu. Protein Cell 2014
185
3

Glutamine addiction: a new therapeutic target in cancer.
David R Wise, Craig B Thompson. Trends Biochem Sci 2010
969
3

Cancer cell metabolism: Warburg and beyond.
Peggy P Hsu, David M Sabatini. Cell 2008
3


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.