Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
Times Cited: 7832
Times Cited: 7832
Times Cited
Times Co-cited
Similarity
The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.
Ralph J DeBerardinis, Julian J Lum, Georgia Hatzivassiliou, Craig B Thompson. Cell Metab 2008
Ralph J DeBerardinis, Julian J Lum, Georgia Hatzivassiliou, Craig B Thompson. Cell Metab 2008
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The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.
Heather R Christofk, Matthew G Vander Heiden, Marian H Harris, Arvind Ramanathan, Robert E Gerszten, Ru Wei, Mark D Fleming, Stuart L Schreiber, Lewis C Cantley. Nature 2008
Heather R Christofk, Matthew G Vander Heiden, Marian H Harris, Arvind Ramanathan, Robert E Gerszten, Ru Wei, Mark D Fleming, Stuart L Schreiber, Lewis C Cantley. Nature 2008
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Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
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Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
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Why do cancers have high aerobic glycolysis?
Robert A Gatenby, Robert J Gillies. Nat Rev Cancer 2004
Robert A Gatenby, Robert J Gillies. Nat Rev Cancer 2004
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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia.
Jung-whan Kim, Irina Tchernyshyov, Gregg L Semenza, Chi V Dang. Cell Metab 2006
Jung-whan Kim, Irina Tchernyshyov, Gregg L Semenza, Chi V Dang. Cell Metab 2006
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Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Matt I Gross, Susan D Demo, Jennifer B Dennison, Lijing Chen, Tania Chernov-Rogan, Bindu Goyal, Julie R Janes, Guy J Laidig, Evan R Lewis, Jim Li,[...]. Mol Cancer Ther 2014
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From Krebs to clinic: glutamine metabolism to cancer therapy.
Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
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Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis.
Javier A Menendez, Ruth Lupu. Nat Rev Cancer 2007
Javier A Menendez, Ruth Lupu. Nat Rev Cancer 2007
4
The multifaceted roles of fatty acid synthesis in cancer.
Florian Röhrig, Almut Schulze. Nat Rev Cancer 2016
Florian Röhrig, Almut Schulze. Nat Rev Cancer 2016
4
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1.
Weibo Luo, Hongxia Hu, Ryan Chang, Jun Zhong, Matthew Knabel, Robert O'Meally, Robert N Cole, Akhilesh Pandey, Gregg L Semenza. Cell 2011
Weibo Luo, Hongxia Hu, Ryan Chang, Jun Zhong, Matthew Knabel, Robert O'Meally, Robert N Cole, Akhilesh Pandey, Gregg L Semenza. Cell 2011
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Akt stimulates aerobic glycolysis in cancer cells.
Rebecca L Elstrom, Daniel E Bauer, Monica Buzzai, Robyn Karnauskas, Marian H Harris, David R Plas, Hongming Zhuang, Ryan M Cinalli, Abass Alavi, Charles M Rudin,[...]. Cancer Res 2004
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Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches.
Karen G de la Cruz-López, Leonardo Josué Castro-Muñoz, Diego O Reyes-Hernández, Alejandro García-Carrancá, Joaquín Manzo-Merino. Front Oncol 2019
Karen G de la Cruz-López, Leonardo Josué Castro-Muñoz, Diego O Reyes-Hernández, Alejandro García-Carrancá, Joaquín Manzo-Merino. Front Oncol 2019
4
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.
Pierre Sonveaux, Frédérique Végran, Thies Schroeder, Melanie C Wergin, Julien Verrax, Zahid N Rabbani, Christophe J De Saedeleer, Kelly M Kennedy, Caroline Diepart, Bénédicte F Jordan,[...]. J Clin Invest 2008
Pierre Sonveaux, Frédérique Végran, Thies Schroeder, Melanie C Wergin, Julien Verrax, Zahid N Rabbani, Christophe J De Saedeleer, Kelly M Kennedy, Caroline Diepart, Bénédicte F Jordan,[...]. J Clin Invest 2008
4
Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion.
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen,[...]. Science 2019
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen,[...]. Science 2019
3
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
3
Glucose metabolism in pig outer retina in light and darkness.
L Wang, P Törnquist, A Bill. Acta Physiol Scand 1997
L Wang, P Törnquist, A Bill. Acta Physiol Scand 1997
3
Glucose metabolism of the inner retina in pigs in darkness and light.
L Wang, P Törnquist, A Bill. Acta Physiol Scand 1997
L Wang, P Törnquist, A Bill. Acta Physiol Scand 1997
3
Glycolytic reliance promotes anabolism in photoreceptors.
Yashodhan Chinchore, Tedi Begaj, David Wu, Eugene Drokhlyansky, Constance L Cepko. Elife 2017
Yashodhan Chinchore, Tedi Begaj, David Wu, Eugene Drokhlyansky, Constance L Cepko. Elife 2017
4
Pyruvate kinase and aspartate-glutamate carrier distributions reveal key metabolic links between neurons and glia in retina.
Ken J Lindsay, Jianhai Du, Stephanie R Sloat, Laura Contreras, Jonathan D Linton, Sally J Turner, Martin Sadilek, Jorgina Satrústegui, James B Hurley. Proc Natl Acad Sci U S A 2014
Ken J Lindsay, Jianhai Du, Stephanie R Sloat, Laura Contreras, Jonathan D Linton, Sally J Turner, Martin Sadilek, Jorgina Satrústegui, James B Hurley. Proc Natl Acad Sci U S A 2014
4
ATP consumption by mammalian rod photoreceptors in darkness and in light.
Haruhisa Okawa, Alapakkam P Sampath, Simon B Laughlin, Gordon L Fain. Curr Biol 2008
Haruhisa Okawa, Alapakkam P Sampath, Simon B Laughlin, Gordon L Fain. Curr Biol 2008
3
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.
Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying,[...]. Nature 2016
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3
Targeting Autophagy in Cancer: Recent Advances and Future Directions.
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Ravi K Amaravadi, Alec C Kimmelman, Jayanta Debnath. Cancer Discov 2019
3
Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.
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Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells.
Sybille Mazurek. Int J Biochem Cell Biol 2011
Sybille Mazurek. Int J Biochem Cell Biol 2011
3
Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation.
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Weiwei Yang, Yan Xia, Haitao Ji, Yanhua Zheng, Ji Liang, Wenhua Huang, Xiang Gao, Kenneth Aldape, Zhimin Lu. Nature 2011
3
Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase.
Xueliang Gao, Haizhen Wang, Jenny J Yang, Xiaowei Liu, Zhi-Ren Liu. Mol Cell 2012
Xueliang Gao, Haizhen Wang, Jenny J Yang, Xiaowei Liu, Zhi-Ren Liu. Mol Cell 2012
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Pyruvate kinase: Function, regulation and role in cancer.
William J Israelsen, Matthew G Vander Heiden. Semin Cell Dev Biol 2015
William J Israelsen, Matthew G Vander Heiden. Semin Cell Dev Biol 2015
3
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses.
Dimitrios Anastasiou, George Poulogiannis, John M Asara, Matthew B Boxer, Jian-kang Jiang, Min Shen, Gary Bellinger, Atsuo T Sasaki, Jason W Locasale, Douglas S Auld,[...]. Science 2011
Dimitrios Anastasiou, George Poulogiannis, John M Asara, Matthew B Boxer, Jian-kang Jiang, Min Shen, Gary Bellinger, Atsuo T Sasaki, Jason W Locasale, Douglas S Auld,[...]. Science 2011
3
Oxygen availability and metabolic adaptations.
Michael S Nakazawa, Brian Keith, M Celeste Simon. Nat Rev Cancer 2016
Michael S Nakazawa, Brian Keith, M Celeste Simon. Nat Rev Cancer 2016
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Tumour acidosis: from the passenger to the driver's seat.
Cyril Corbet, Olivier Feron. Nat Rev Cancer 2017
Cyril Corbet, Olivier Feron. Nat Rev Cancer 2017
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Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology.
F P Kuhajda. Nutrition 2000
F P Kuhajda. Nutrition 2000
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Targeting Metabolism for Cancer Therapy.
Alba Luengo, Dan Y Gui, Matthew G Vander Heiden. Cell Chem Biol 2017
Alba Luengo, Dan Y Gui, Matthew G Vander Heiden. Cell Chem Biol 2017
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Tumor glycolysis as a target for cancer therapy: progress and prospects.
Shanmugasundaram Ganapathy-Kanniappan, Jean-Francois H Geschwind. Mol Cancer 2013
Shanmugasundaram Ganapathy-Kanniappan, Jean-Francois H Geschwind. Mol Cancer 2013
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Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR.
Jan H Ardenkjaer-Larsen, Björn Fridlund, Andreas Gram, Georg Hansson, Lennart Hansson, Mathilde H Lerche, Rolf Servin, Mikkel Thaning, Klaes Golman. Proc Natl Acad Sci U S A 2003
Jan H Ardenkjaer-Larsen, Björn Fridlund, Andreas Gram, Georg Hansson, Lennart Hansson, Mathilde H Lerche, Rolf Servin, Mikkel Thaning, Klaes Golman. Proc Natl Acad Sci U S A 2003
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Inhibitory effect of tumor cell-derived lactic acid on human T cells.
Karin Fischer, Petra Hoffmann, Simon Voelkl, Norbert Meidenbauer, Julia Ammer, Matthias Edinger, Eva Gottfried, Sabine Schwarz, Gregor Rothe, Sabine Hoves,[...]. Blood 2007
Karin Fischer, Petra Hoffmann, Simon Voelkl, Norbert Meidenbauer, Julia Ammer, Matthias Edinger, Eva Gottfried, Sabine Schwarz, Gregor Rothe, Sabine Hoves,[...]. Blood 2007
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Regulation of the pentose phosphate pathway in cancer.
Peng Jiang, Wenjing Du, Mian Wu. Protein Cell 2014
Peng Jiang, Wenjing Du, Mian Wu. Protein Cell 2014
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Glutamine addiction: a new therapeutic target in cancer.
David R Wise, Craig B Thompson. Trends Biochem Sci 2010
David R Wise, Craig B Thompson. Trends Biochem Sci 2010
3
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.