Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
Times Cited: 8561
Times Cited: 8561
Times Cited
Times Co-cited
Similarity
13
The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
13
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
10
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
10
Why do cancers have high aerobic glycolysis?
Robert A Gatenby, Robert J Gillies. Nat Rev Cancer 2004
Robert A Gatenby, Robert J Gillies. Nat Rev Cancer 2004
5
The Warburg effect: essential part of metabolic reprogramming and central contributor to cancer progression.
Peter Vaupel, Heinz Schmidberger, Arnulf Mayer. Int J Radiat Biol 2019
Peter Vaupel, Heinz Schmidberger, Arnulf Mayer. Int J Radiat Biol 2019
5
Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
5
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
5
4
Akt stimulates aerobic glycolysis in cancer cells.
Rebecca L Elstrom, Daniel E Bauer, Monica Buzzai, Robyn Karnauskas, Marian H Harris, David R Plas, Hongming Zhuang, Ryan M Cinalli, Abass Alavi, Charles M Rudin,[...]. Cancer Res 2004
Rebecca L Elstrom, Daniel E Bauer, Monica Buzzai, Robyn Karnauskas, Marian H Harris, David R Plas, Hongming Zhuang, Ryan M Cinalli, Abass Alavi, Charles M Rudin,[...]. Cancer Res 2004
4
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.
Frank Weinberg, Robert Hamanaka, William W Wheaton, Samuel Weinberg, Joy Joseph, Marcos Lopez, Balaraman Kalyanaraman, Gökhan M Mutlu, G R Scott Budinger, Navdeep S Chandel. Proc Natl Acad Sci U S A 2010
Frank Weinberg, Robert Hamanaka, William W Wheaton, Samuel Weinberg, Joy Joseph, Marcos Lopez, Balaraman Kalyanaraman, Gökhan M Mutlu, G R Scott Budinger, Navdeep S Chandel. Proc Natl Acad Sci U S A 2010
4
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.
Lenny Dang, David W White, Stefan Gross, Bryson D Bennett, Mark A Bittinger, Edward M Driggers, Valeria R Fantin, Hyun Gyung Jang, Shengfang Jin, Marie C Keenan,[...]. Nature 2009
Lenny Dang, David W White, Stefan Gross, Bryson D Bennett, Mark A Bittinger, Edward M Driggers, Valeria R Fantin, Hyun Gyung Jang, Shengfang Jin, Marie C Keenan,[...]. Nature 2009
4
Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
4
Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
Nissim Hay. Nat Rev Cancer 2016
Nissim Hay. Nat Rev Cancer 2016
4
Targeting mitochondrial glutaminase activity inhibits oncogenic transformation.
Jian-Bin Wang, Jon W Erickson, Reina Fuji, Sekar Ramachandran, Ping Gao, Ramani Dinavahi, Kristin F Wilson, Andre L B Ambrosio, Sandra M G Dias, Chi V Dang,[...]. Cancer Cell 2010
Jian-Bin Wang, Jon W Erickson, Reina Fuji, Sekar Ramachandran, Ping Gao, Ramani Dinavahi, Kristin F Wilson, Andre L B Ambrosio, Sandra M G Dias, Chi V Dang,[...]. Cancer Cell 2010
4
4
Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
4
Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.
Candace M Cham, Gregory Driessens, James P O'Keefe, Thomas F Gajewski. Eur J Immunol 2008
Candace M Cham, Gregory Driessens, James P O'Keefe, Thomas F Gajewski. Eur J Immunol 2008
4
Cancer Statistics, 2021.
Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal. CA Cancer J Clin 2021
Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal. CA Cancer J Clin 2021
4
Posttranscriptional control of T cell effector function by aerobic glycolysis.
Chih-Hao Chang, Jonathan D Curtis, Leonard B Maggi, Brandon Faubert, Alejandro V Villarino, David O'Sullivan, Stanley Ching-Cheng Huang, Gerritje J W van der Windt, Julianna Blagih, Jing Qiu,[...]. Cell 2013
Chih-Hao Chang, Jonathan D Curtis, Leonard B Maggi, Brandon Faubert, Alejandro V Villarino, David O'Sullivan, Stanley Ching-Cheng Huang, Gerritje J W van der Windt, Julianna Blagih, Jing Qiu,[...]. Cell 2013
4
Revisiting the Warburg effect: historical dogma versus current understanding.
Peter Vaupel, Gabriele Multhoff. J Physiol 2021
Peter Vaupel, Gabriele Multhoff. J Physiol 2021
6
Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells.
Aaron M Hosios, Vivian C Hecht, Laura V Danai, Marc O Johnson, Jeffrey C Rathmell, Matthew L Steinhauser, Scott R Manalis, Matthew G Vander Heiden. Dev Cell 2016
Aaron M Hosios, Vivian C Hecht, Laura V Danai, Marc O Johnson, Jeffrey C Rathmell, Matthew L Steinhauser, Scott R Manalis, Matthew G Vander Heiden. Dev Cell 2016
4
Fasting and cancer: molecular mechanisms and clinical application.
Alessio Nencioni, Irene Caffa, Salvatore Cortellino, Valter D Longo. Nat Rev Cancer 2018
Alessio Nencioni, Irene Caffa, Salvatore Cortellino, Valter D Longo. Nat Rev Cancer 2018
4
Curcumin inhibits aerobic glycolysis and induces mitochondrial-mediated apoptosis through hexokinase II in human colorectal cancer cells in vitro.
Ke Wang, Hua Fan, Qingsen Chen, Guojian Ma, Ming Zhu, Xiaomei Zhang, Yuanying Zhang, Jun Yu. Anticancer Drugs 2015
Ke Wang, Hua Fan, Qingsen Chen, Guojian Ma, Ming Zhu, Xiaomei Zhang, Yuanying Zhang, Jun Yu. Anticancer Drugs 2015
6
MYC, Metabolism, and Cancer.
Zachary E Stine, Zandra E Walton, Brian J Altman, Annie L Hsieh, Chi V Dang. Cancer Discov 2015
Zachary E Stine, Zandra E Walton, Brian J Altman, Annie L Hsieh, Chi V Dang. Cancer Discov 2015
3
Cancer metabolism: fatty acid oxidation in the limelight.
Arkaitz Carracedo, Lewis C Cantley, Pier Paolo Pandolfi. Nat Rev Cancer 2013
Arkaitz Carracedo, Lewis C Cantley, Pier Paolo Pandolfi. Nat Rev Cancer 2013
3
Serine, glycine and one-carbon units: cancer metabolism in full circle.
Jason W Locasale. Nat Rev Cancer 2013
Jason W Locasale. Nat Rev Cancer 2013
3
Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K.
Rupert Courtnay, Darleen C Ngo, Neha Malik, Katherine Ververis, Stephanie M Tortorella, Tom C Karagiannis. Mol Biol Rep 2015
Rupert Courtnay, Darleen C Ngo, Neha Malik, Katherine Ververis, Stephanie M Tortorella, Tom C Karagiannis. Mol Biol Rep 2015
3
Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
3
Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer.
R J DeBerardinis, T Cheng. Oncogene 2010
R J DeBerardinis, T Cheng. Oncogene 2010
3
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.
Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang, Yun-Sil Lee, Kayoko Kita, Takafumi Ochi, Karen I Zeller, Angelo M De Marzo, Jennifer E Van Eyk, Joshua T Mendell,[...]. Nature 2009
Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang, Yun-Sil Lee, Kayoko Kita, Takafumi Ochi, Karen I Zeller, Angelo M De Marzo, Jennifer E Van Eyk, Joshua T Mendell,[...]. Nature 2009
3
Bidirectional transport of amino acids regulates mTOR and autophagy.
Paul Nicklin, Philip Bergman, Bailin Zhang, Ellen Triantafellow, Henry Wang, Beat Nyfeler, Haidi Yang, Marc Hild, Charles Kung, Christopher Wilson,[...]. Cell 2009
Paul Nicklin, Philip Bergman, Bailin Zhang, Ellen Triantafellow, Henry Wang, Beat Nyfeler, Haidi Yang, Marc Hild, Charles Kung, Christopher Wilson,[...]. Cell 2009
3
Serine and glycine metabolism in cancer.
Ivano Amelio, Francesca Cutruzzolá, Alexey Antonov, Massimiliano Agostini, Gerry Melino. Trends Biochem Sci 2014
Ivano Amelio, Francesca Cutruzzolá, Alexey Antonov, Massimiliano Agostini, Gerry Melino. Trends Biochem Sci 2014
3
Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism.
Wei Yang, Yibing Bai, Ying Xiong, Jin Zhang, Shuokai Chen, Xiaojun Zheng, Xiangbo Meng, Lunyi Li, Jing Wang, Chenguang Xu,[...]. Nature 2016
Wei Yang, Yibing Bai, Ying Xiong, Jin Zhang, Shuokai Chen, Xiaojun Zheng, Xiangbo Meng, Lunyi Li, Jing Wang, Chenguang Xu,[...]. Nature 2016
3
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis.
Javier A Menendez, Ruth Lupu. Nat Rev Cancer 2007
Javier A Menendez, Ruth Lupu. Nat Rev Cancer 2007
3
Understanding the Intersections between Metabolism and Cancer Biology.
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
3
The multifaceted roles of fatty acid synthesis in cancer.
Florian Röhrig, Almut Schulze. Nat Rev Cancer 2016
Florian Röhrig, Almut Schulze. Nat Rev Cancer 2016
3
De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy.
T Mashima, H Seimiya, T Tsuruo. Br J Cancer 2009
T Mashima, H Seimiya, T Tsuruo. Br J Cancer 2009
3
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal.
Jianjiong Gao, Bülent Arman Aksoy, Ugur Dogrusoz, Gideon Dresdner, Benjamin Gross, S Onur Sumer, Yichao Sun, Anders Jacobsen, Rileen Sinha, Erik Larsson,[...]. Sci Signal 2013
Jianjiong Gao, Bülent Arman Aksoy, Ugur Dogrusoz, Gideon Dresdner, Benjamin Gross, S Onur Sumer, Yichao Sun, Anders Jacobsen, Rileen Sinha, Erik Larsson,[...]. Sci Signal 2013
3
Targeting lactate metabolism for cancer therapeutics.
Joanne R Doherty, John L Cleveland. J Clin Invest 2013
Joanne R Doherty, John L Cleveland. J Clin Invest 2013
3
Metabolic Heterogeneity in Human Lung Tumors.
Christopher T Hensley, Brandon Faubert, Qing Yuan, Naama Lev-Cohain, Eunsook Jin, Jiyeon Kim, Lei Jiang, Bookyung Ko, Rachael Skelton, Laurin Loudat,[...]. Cell 2016
Christopher T Hensley, Brandon Faubert, Qing Yuan, Naama Lev-Cohain, Eunsook Jin, Jiyeon Kim, Lei Jiang, Bookyung Ko, Rachael Skelton, Laurin Loudat,[...]. Cell 2016
3
The PRIDE database and related tools and resources in 2019: improving support for quantification data.
Yasset Perez-Riverol, Attila Csordas, Jingwen Bai, Manuel Bernal-Llinares, Suresh Hewapathirana, Deepti J Kundu, Avinash Inuganti, Johannes Griss, Gerhard Mayer, Martin Eisenacher,[...]. Nucleic Acids Res 2019
Yasset Perez-Riverol, Attila Csordas, Jingwen Bai, Manuel Bernal-Llinares, Suresh Hewapathirana, Deepti J Kundu, Avinash Inuganti, Johannes Griss, Gerhard Mayer, Martin Eisenacher,[...]. Nucleic Acids Res 2019
3
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.
Heather R Christofk, Matthew G Vander Heiden, Marian H Harris, Arvind Ramanathan, Robert E Gerszten, Ru Wei, Mark D Fleming, Stuart L Schreiber, Lewis C Cantley. Nature 2008
Heather R Christofk, Matthew G Vander Heiden, Marian H Harris, Arvind Ramanathan, Robert E Gerszten, Ru Wei, Mark D Fleming, Stuart L Schreiber, Lewis C Cantley. Nature 2008
3
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.