A citation-based method for searching scientific literature

Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
Times Cited: 8561







List of co-cited articles
400 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
22

On the origin of cancer cells.
O WARBURG. Science 1956
14

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
13

The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
13

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
10

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
10

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
7

Why do cancers have high aerobic glycolysis?
Robert A Gatenby, Robert J Gillies. Nat Rev Cancer 2004
5


Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
5

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
5

mTOR signaling in growth control and disease.
Mathieu Laplante, David M Sabatini. Cell 2012
4

Akt stimulates aerobic glycolysis in cancer cells.
Rebecca L Elstrom, Daniel E Bauer, Monica Buzzai, Robyn Karnauskas, Marian H Harris, David R Plas, Hongming Zhuang, Ryan M Cinalli, Abass Alavi, Charles M Rudin,[...]. Cancer Res 2004
4

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.
Frank Weinberg, Robert Hamanaka, William W Wheaton, Samuel Weinberg, Joy Joseph, Marcos Lopez, Balaraman Kalyanaraman, Gökhan M Mutlu, G R Scott Budinger, Navdeep S Chandel. Proc Natl Acad Sci U S A 2010
4

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.
Lenny Dang, David W White, Stefan Gross, Bryson D Bennett, Mark A Bittinger, Edward M Driggers, Valeria R Fantin, Hyun Gyung Jang, Shengfang Jin, Marie C Keenan,[...]. Nature 2009
4

Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
4


THE METABOLISM OF TUMORS IN THE BODY.
O Warburg, F Wind, E Negelein. J Gen Physiol 1927
4

Targeting mitochondrial glutaminase activity inhibits oncogenic transformation.
Jian-Bin Wang, Jon W Erickson, Reina Fuji, Sekar Ramachandran, Ping Gao, Ramani Dinavahi, Kristin F Wilson, Andre L B Ambrosio, Sandra M G Dias, Chi V Dang,[...]. Cancer Cell 2010
551
4

Cancer's molecular sweet tooth and the Warburg effect.
Jung-whan Kim, Chi V Dang. Cancer Res 2006
854
4

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
4

Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.
Candace M Cham, Gregory Driessens, James P O'Keefe, Thomas F Gajewski. Eur J Immunol 2008
220
4

Cancer Statistics, 2021.
Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal. CA Cancer J Clin 2021
4

Posttranscriptional control of T cell effector function by aerobic glycolysis.
Chih-Hao Chang, Jonathan D Curtis, Leonard B Maggi, Brandon Faubert, Alejandro V Villarino, David O'Sullivan, Stanley Ching-Cheng Huang, Gerritje J W van der Windt, Julianna Blagih, Jing Qiu,[...]. Cell 2013
4


Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells.
Aaron M Hosios, Vivian C Hecht, Laura V Danai, Marc O Johnson, Jeffrey C Rathmell, Matthew L Steinhauser, Scott R Manalis, Matthew G Vander Heiden. Dev Cell 2016
295
4

Fasting and cancer: molecular mechanisms and clinical application.
Alessio Nencioni, Irene Caffa, Salvatore Cortellino, Valter D Longo. Nat Rev Cancer 2018
147
4

Curcumin inhibits aerobic glycolysis and induces mitochondrial-mediated apoptosis through hexokinase II in human colorectal cancer cells in vitro.
Ke Wang, Hua Fan, Qingsen Chen, Guojian Ma, Ming Zhu, Xiaomei Zhang, Yuanying Zhang, Jun Yu. Anticancer Drugs 2015
45
6

MYC, Metabolism, and Cancer.
Zachary E Stine, Zandra E Walton, Brian J Altman, Annie L Hsieh, Chi V Dang. Cancer Discov 2015
603
3

Cancer metabolism: fatty acid oxidation in the limelight.
Arkaitz Carracedo, Lewis C Cantley, Pier Paolo Pandolfi. Nat Rev Cancer 2013
661
3


Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K.
Rupert Courtnay, Darleen C Ngo, Neha Malik, Katherine Ververis, Stephanie M Tortorella, Tom C Karagiannis. Mol Biol Rep 2015
259
3

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
3


c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.
Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang, Yun-Sil Lee, Kayoko Kita, Takafumi Ochi, Karen I Zeller, Angelo M De Marzo, Jennifer E Van Eyk, Joshua T Mendell,[...]. Nature 2009
3

Bidirectional transport of amino acids regulates mTOR and autophagy.
Paul Nicklin, Philip Bergman, Bailin Zhang, Ellen Triantafellow, Henry Wang, Beat Nyfeler, Haidi Yang, Marc Hild, Charles Kung, Christopher Wilson,[...]. Cell 2009
3

Serine and glycine metabolism in cancer.
Ivano Amelio, Francesca Cutruzzolá, Alexey Antonov, Massimiliano Agostini, Gerry Melino. Trends Biochem Sci 2014
492
3

Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism.
Wei Yang, Yibing Bai, Ying Xiong, Jin Zhang, Shuokai Chen, Xiaojun Zheng, Xiangbo Meng, Lunyi Li, Jing Wang, Chenguang Xu,[...]. Nature 2016
370
3


Understanding the Intersections between Metabolism and Cancer Biology.
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
908
3

The multifaceted roles of fatty acid synthesis in cancer.
Florian Röhrig, Almut Schulze. Nat Rev Cancer 2016
537
3


The hallmarks of cancer.
D Hanahan, R A Weinberg. Cell 2000
3

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal.
Jianjiong Gao, Bülent Arman Aksoy, Ugur Dogrusoz, Gideon Dresdner, Benjamin Gross, S Onur Sumer, Yichao Sun, Anders Jacobsen, Rileen Sinha, Erik Larsson,[...]. Sci Signal 2013
3

Targeting HIF-1 for cancer therapy.
Gregg L Semenza. Nat Rev Cancer 2003
3

Targeting lactate metabolism for cancer therapeutics.
Joanne R Doherty, John L Cleveland. J Clin Invest 2013
582
3

Metabolic Heterogeneity in Human Lung Tumors.
Christopher T Hensley, Brandon Faubert, Qing Yuan, Naama Lev-Cohain, Eunsook Jin, Jiyeon Kim, Lei Jiang, Bookyung Ko, Rachael Skelton, Laurin Loudat,[...]. Cell 2016
555
3

The PRIDE database and related tools and resources in 2019: improving support for quantification data.
Yasset Perez-Riverol, Attila Csordas, Jingwen Bai, Manuel Bernal-Llinares, Suresh Hewapathirana, Deepti J Kundu, Avinash Inuganti, Johannes Griss, Gerhard Mayer, Martin Eisenacher,[...]. Nucleic Acids Res 2019
3

Serine and one-carbon metabolism in cancer.
Ming Yang, Karen H Vousden. Nat Rev Cancer 2016
391
3

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.
Heather R Christofk, Matthew G Vander Heiden, Marian H Harris, Arvind Ramanathan, Robert E Gerszten, Ru Wei, Mark D Fleming, Stuart L Schreiber, Lewis C Cantley. Nature 2008
3


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.