A Haouala, B Zanolari, B Rochat, M Montemurro, K Zaman, M A Duchosal, H B Ris, S Leyvraz, N Widmer, L A Decosterd. J Chromatogr B Analyt Technol Biomed Life Sci 2009
Times Cited: 139
Times Cited: 139
Times Cited
Times Co-cited
Similarity
Simultaneous determination of nine tyrosine kinase inhibitors by 96-well solid-phase extraction and ultra performance LC/MS-MS.
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38
Development and clinical application of a LC-MS/MS method for simultaneous determination of various tyrosine kinase inhibitors in human plasma.
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43
An automated method for the measurement of a range of tyrosine kinase inhibitors in human plasma or serum using turbulent flow liquid chromatography-tandem mass spectrometry.
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Review of therapeutic drug monitoring of anticancer drugs part two--targeted therapies.
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Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia.
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23
Method development and validation for the quantification of dasatinib, erlotinib, gefitinib, imatinib, lapatinib, nilotinib, sorafenib and sunitinib in human plasma by liquid chromatography coupled with tandem mass spectrometry.
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34
New HPLC-MS method for the simultaneous quantification of the antileukemia drugs imatinib, dasatinib, and nilotinib in human plasma.
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Silvia De Francia, Antonio D'Avolio, Francesca De Martino, Elisa Pirro, Lorena Baietto, Marco Siccardi, Marco Simiele, Silvia Racca, Giuseppe Saglio, Francesco Di Carlo,[...]. J Chromatogr B Analyt Technol Biomed Life Sci 2009
30
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study.
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Simultaneous analysis of anticancer agents bortezomib, imatinib, nilotinib, dasatinib, erlotinib, lapatinib, sorafenib, sunitinib and vandetanib in human plasma using LC/MS/MS.
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30
Simple and selective method for the determination of various tyrosine kinase inhibitors used in the clinical setting by liquid chromatography tandem mass spectrometry.
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25
Practical guidelines for therapeutic drug monitoring of anticancer tyrosine kinase inhibitors: focus on the pharmacokinetic targets.
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Huixin Yu, Neeltje Steeghs, Cynthia M Nijenhuis, Jan H M Schellens, Jos H Beijnen, Alwin D R Huitema. Clin Pharmacokinet 2014
16
Relationship of imatinib-free plasma levels and target genotype with efficacy and tolerability.
N Widmer, L A Decosterd, S Leyvraz, M A Duchosal, A Rosselet, M Debiec-Rychter, C Csajka, J Biollaz, T Buclin. Br J Cancer 2008
N Widmer, L A Decosterd, S Leyvraz, M A Duchosal, A Rosselet, M Debiec-Rychter, C Csajka, J Biollaz, T Buclin. Br J Cancer 2008
16
Imatinib plasma levels are correlated with clinical benefit in patients with unresectable/metastatic gastrointestinal stromal tumors.
George D Demetri, Yanfeng Wang, Elisabeth Wehrle, Amy Racine, Zariana Nikolova, Charles D Blanke, Heikki Joensuu, Margaret von Mehren. J Clin Oncol 2009
George D Demetri, Yanfeng Wang, Elisabeth Wehrle, Amy Racine, Zariana Nikolova, Charles D Blanke, Heikki Joensuu, Margaret von Mehren. J Clin Oncol 2009
14
A validated assay for the simultaneous quantification of six tyrosine kinase inhibitors and two active metabolites in human serum using liquid chromatography coupled with tandem mass spectrometry.
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Nielka P van Erp, Djoeke de Wit, Henk-Jan Guchelaar, Hans Gelderblom, Trees J Hessing, Jan den Hartigh. J Chromatogr B Analyt Technol Biomed Life Sci 2013
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Clinical pharmacokinetics of tyrosine kinase inhibitors.
Nielka P van Erp, Hans Gelderblom, Henk-Jan Guchelaar. Cancer Treat Rev 2009
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Quantification of sunitinib in human plasma by high-performance liquid chromatography-tandem mass spectrometry.
Patton Minkin, Ming Zhao, Zhaoyuan Chen, Jan Ouwerkerk, Hans Gelderblom, Sharyn D Baker. J Chromatogr B Analyt Technol Biomed Life Sci 2008
Patton Minkin, Ming Zhao, Zhaoyuan Chen, Jan Ouwerkerk, Hans Gelderblom, Sharyn D Baker. J Chromatogr B Analyt Technol Biomed Life Sci 2008
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Moving towards dose individualization of tyrosine kinase inhibitors.
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Heinz-Josef Klümpen, Caroline F Samer, Ron H J Mathijssen, Jan H M Schellens, Howard Gurney. Cancer Treat Rev 2011
14
Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis.
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12
Bioanalytical method for the quantification of sunitinib and its n-desethyl metabolite SU12662 in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry.
Peter de Bruijn, Stefan Sleijfer, Mei-Ho Lam, Ron H J Mathijssen, Erik A C Wiemer, Walter J Loos. J Pharm Biomed Anal 2010
Peter de Bruijn, Stefan Sleijfer, Mei-Ho Lam, Ron H J Mathijssen, Erik A C Wiemer, Walter J Loos. J Pharm Biomed Anal 2010
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Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer.
Sandrine Faivre, Catherine Delbaldo, Karina Vera, Caroline Robert, Stéphanie Lozahic, Nathalie Lassau, Carlo Bello, Samuel Deprimo, Nicoletta Brega, Giorgio Massimini,[...]. J Clin Oncol 2006
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11
Population pharmacokinetics of imatinib and the role of alpha-acid glycoprotein.
N Widmer, L A Decosterd, C Csajka, S Leyvraz, M A Duchosal, A Rosselet, B Rochat, C B Eap, H Henry, J Biollaz,[...]. Br J Clin Pharmacol 2006
N Widmer, L A Decosterd, C Csajka, S Leyvraz, M A Duchosal, A Rosselet, B Rochat, C B Eap, H Henry, J Biollaz,[...]. Br J Clin Pharmacol 2006
11
Quantification of sunitinib in mouse plasma, brain tumor and normal brain using liquid chromatography-electrospray ionization-tandem mass spectrometry and pharmacokinetic application.
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Qingyu Zhou, James M Gallo. J Pharm Biomed Anal 2010
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Development of a high-performance liquid chromatographic-mass spectrometric method for the determination of cellular levels of the tyrosine kinase inhibitors lapatinib and dasatinib.
Sandra Roche, Gillian McMahon, Martin Clynes, Robert O'Connor. J Chromatogr B Analyt Technol Biomed Life Sci 2009
Sandra Roche, Gillian McMahon, Martin Clynes, Robert O'Connor. J Chromatogr B Analyt Technol Biomed Life Sci 2009
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Evidence for therapeutic drug monitoring of targeted anticancer therapies.
Bo Gao, Shang Yeap, Arthur Clements, Bavanthi Balakrishnar, Mark Wong, Howard Gurney. J Clin Oncol 2012
Bo Gao, Shang Yeap, Arthur Clements, Bavanthi Balakrishnar, Mark Wong, Howard Gurney. J Clin Oncol 2012
11
Determination of lapatinib (GW572016) in human plasma by liquid chromatography electrospray tandem mass spectrometry (LC-ESI-MS/MS).
Feng Bai, Burgess B Freeman, Charles H Fraga, Maryam Fouladi, Clinton F Stewart. J Chromatogr B Analyt Technol Biomed Life Sci 2006
Feng Bai, Burgess B Freeman, Charles H Fraga, Maryam Fouladi, Clinton F Stewart. J Chromatogr B Analyt Technol Biomed Life Sci 2006
25
Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS.
B K Matuszewski, M L Constanzer, C M Chavez-Eng. Anal Chem 2003
B K Matuszewski, M L Constanzer, C M Chavez-Eng. Anal Chem 2003
10
Simultaneous measurement of imatinib, nilotinib and dasatinib in dried blood spot by ultra high performance liquid chromatography tandem mass spectrometry.
Eva Kralj, Jurij Trontelj, Tadej Pajič, Albin Kristl. J Chromatogr B Analyt Technol Biomed Life Sci 2012
Eva Kralj, Jurij Trontelj, Tadej Pajič, Albin Kristl. J Chromatogr B Analyt Technol Biomed Life Sci 2012
22
Pharmacokinetic/pharmacodynamic correlation and blood-level testing in imatinib therapy for chronic myeloid leukemia.
J E Cortes, M J Egorin, F Guilhot, M Molimard, F-X Mahon. Leukemia 2009
J E Cortes, M J Egorin, F Guilhot, M Molimard, F-X Mahon. Leukemia 2009
12
Pharmacokinetics and pharmacodynamics of imatinib in a phase I trial with chronic myeloid leukemia patients.
Bin Peng, Michael Hayes, Debra Resta, Amy Racine-Poon, Brian J Druker, Moshe Talpaz, Charles L Sawyers, Marianne Rosamilia, John Ford, Peter Lloyd,[...]. J Clin Oncol 2004
Bin Peng, Michael Hayes, Debra Resta, Amy Racine-Poon, Brian J Druker, Moshe Talpaz, Charles L Sawyers, Marianne Rosamilia, John Ford, Peter Lloyd,[...]. J Clin Oncol 2004
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Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib.
David Marin, Alexandra Bazeos, Francois-Xavier Mahon, Lina Eliasson, Dragana Milojkovic, Marco Bua, Jane F Apperley, Richard Szydlo, Ritti Desai, Kasia Kozlowski,[...]. J Clin Oncol 2010
David Marin, Alexandra Bazeos, Francois-Xavier Mahon, Lina Eliasson, Dragana Milojkovic, Marco Bua, Jane F Apperley, Richard Szydlo, Ritti Desai, Kasia Kozlowski,[...]. J Clin Oncol 2010
9
9
A new HPLC-UV validated method for therapeutic drug monitoring of tyrosine kinase inhibitors in leukemic patients.
Elisa Pirro, Silvia De Francia, Francesca De Martino, Carmen Fava, Stefano Ulisciani, Giovanna Rege Cambrin, Silvia Racca, Giuseppe Saglio, Francesco Di Carlo. J Chromatogr Sci 2011
Elisa Pirro, Silvia De Francia, Francesca De Martino, Carmen Fava, Stefano Ulisciani, Giovanna Rege Cambrin, Silvia Racca, Giuseppe Saglio, Francesco Di Carlo. J Chromatogr Sci 2011
33
Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase.
Richard A Larson, Ophelia Q P Yin, Andreas Hochhaus, Giuseppe Saglio, Richard E Clark, Hirohisa Nakamae, Neil J Gallagher, Eren Demirhan, Timothy P Hughes, Hagop M Kantarjian,[...]. Eur J Clin Pharmacol 2012
Richard A Larson, Ophelia Q P Yin, Andreas Hochhaus, Giuseppe Saglio, Richard E Clark, Hirohisa Nakamae, Neil J Gallagher, Eren Demirhan, Timothy P Hughes, Hagop M Kantarjian,[...]. Eur J Clin Pharmacol 2012
12
Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas.
Howard A Burris, Herbert I Hurwitz, E Claire Dees, Afshin Dowlati, Kimberly L Blackwell, Bert O'Neil, Paul K Marcom, Matthew J Ellis, Beth Overmoyer, Suzanne F Jones,[...]. J Clin Oncol 2005
Howard A Burris, Herbert I Hurwitz, E Claire Dees, Afshin Dowlati, Kimberly L Blackwell, Bert O'Neil, Paul K Marcom, Matthew J Ellis, Beth Overmoyer, Suzanne F Jones,[...]. J Clin Oncol 2005
9
A high-performance liquid chromatography-mass spectrometry assay for quantitation of the tyrosine kinase inhibitor nilotinib in human plasma and serum.
Robert A Parise, Merrill J Egorin, Susan M Christner, Dhvani D Shah, Wei Zhou, Jan H Beumer. J Chromatogr B Analyt Technol Biomed Life Sci 2009
Robert A Parise, Merrill J Egorin, Susan M Christner, Dhvani D Shah, Wei Zhou, Jan H Beumer. J Chromatogr B Analyt Technol Biomed Life Sci 2009
42
Imatinib assay by HPLC with photodiode-array UV detection in plasma from patients with chronic myeloid leukemia: Comparison with LC-MS/MS.
Olivia Roth, Odile Spreux-Varoquaux, Stephane Bouchet, Philippe Rousselot, Sylvie Castaigne, Sophie Rigaudeau, Victoria Raggueneau, Patrice Therond, Philippe Devillier, Mathieu Molimard,[...]. Clin Chim Acta 2010
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A routine feasible HPLC analysis for the anti-angiogenic tyrosine kinase inhibitor, sunitinib, and its main metabolite, SU12662, in plasma.
Marie-Christine Etienne-Grimaldi, Nicole Renée, Hassan Izzedine, Gérard Milano. J Chromatogr B Analyt Technol Biomed Life Sci 2009
Marie-Christine Etienne-Grimaldi, Nicole Renée, Hassan Izzedine, Gérard Milano. J Chromatogr B Analyt Technol Biomed Life Sci 2009
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Development and validation of a liquid chromatography/tandem mass spectrometry procedure for the quantification of sunitinib (SU11248) and its active metabolite, N-desethyl sunitinib (SU12662), in human plasma: application to an explorative study.
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Michael Rodamer, Paul W Elsinghorst, Martina Kinzig, Michael Gütschow, Fritz Sörgel. J Chromatogr B Analyt Technol Biomed Life Sci 2011
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Validation of an HPLC-UV method for sorafenib determination in human plasma and application to cancer patients in routine clinical practice.
B Blanchet, B Billemont, J Cramard, A S Benichou, S Chhun, L Harcouet, S Ropert, A Dauphin, F Goldwasser, M Tod. J Pharm Biomed Anal 2009
B Blanchet, B Billemont, J Cramard, A S Benichou, S Chhun, L Harcouet, S Ropert, A Dauphin, F Goldwasser, M Tod. J Pharm Biomed Anal 2009
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Determination of imatinib (Gleevec) in human plasma by solid-phase extraction-liquid chromatography-ultraviolet absorbance detection.
N Widmer, A Béguin, B Rochat, T Buclin, T Kovacsovics, M A Duchosal, S Leyvraz, A Rosselet, J Biollaz, L A Decosterd. J Chromatogr B Analyt Technol Biomed Life Sci 2004
N Widmer, A Béguin, B Rochat, T Buclin, T Kovacsovics, M A Duchosal, S Leyvraz, A Rosselet, J Biollaz, L A Decosterd. J Chromatogr B Analyt Technol Biomed Life Sci 2004
17
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.
Dirk B Mendel, A Douglas Laird, Xiaohua Xin, Sharianne G Louie, James G Christensen, Guangmin Li, Randall E Schreck, Tinya J Abrams, Theresa J Ngai, Leslie B Lee,[...]. Clin Cancer Res 2003
Dirk B Mendel, A Douglas Laird, Xiaohua Xin, Sharianne G Louie, James G Christensen, Guangmin Li, Randall E Schreck, Tinya J Abrams, Theresa J Ngai, Leslie B Lee,[...]. Clin Cancer Res 2003
8
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis.
Scott M Wilhelm, Christopher Carter, Liya Tang, Dean Wilkie, Angela McNabola, Hong Rong, Charles Chen, Xiaomei Zhang, Patrick Vincent, Mark McHugh,[...]. Cancer Res 2004
Scott M Wilhelm, Christopher Carter, Liya Tang, Dean Wilkie, Angela McNabola, Hong Rong, Charles Chen, Xiaomei Zhang, Patrick Vincent, Mark McHugh,[...]. Cancer Res 2004
8
Simultaneous determination of nilotinib, imatinib and its main metabolite (CGP-74588) in human plasma by ultra-violet high performance liquid chromatography.
Andrea Davies, Alison K Hayes, Katy Knight, Sarah J Watmough, Munir Pirmohamed, Richard E Clark. Leuk Res 2010
Andrea Davies, Alison K Hayes, Katy Knight, Sarah J Watmough, Munir Pirmohamed, Richard E Clark. Leuk Res 2010
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Quantification of imatinib in human plasma by high-performance liquid chromatography-tandem mass spectrometry.
Karine Titier, Stéphane Picard, Dominique Ducint, Emmanuelle Teilhet, Nicholas Moore, Patrice Berthaud, François-Xavier Mahon, Mathieu Molimard. Ther Drug Monit 2005
Karine Titier, Stéphane Picard, Dominique Ducint, Emmanuelle Teilhet, Nicholas Moore, Patrice Berthaud, François-Xavier Mahon, Mathieu Molimard. Ther Drug Monit 2005
11
Plasma exposure of imatinib and its correlation with clinical response in the Tyrosine Kinase Inhibitor Optimization and Selectivity Trial.
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François Guilhot, Timothy P Hughes, Jorge Cortes, Brian J Druker, Michele Baccarani, Insa Gathmann, Michael Hayes, Camille Granvil, Yanfeng Wang. Haematologica 2012
10
A validated LC-MS/MS assay for the simultaneous determination of the anti-leukemic agent dasatinib and two pharmacologically active metabolites in human plasma: application to a clinical pharmacokinetic study.
Michael T Furlong, Shruti Agrawal, Dara Hawthorne, Michael Lago, Steve Unger, Linda Krueger, Bruce Stouffer. J Pharm Biomed Anal 2012
Michael T Furlong, Shruti Agrawal, Dara Hawthorne, Michael Lago, Steve Unger, Linda Krueger, Bruce Stouffer. J Pharm Biomed Anal 2012
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Development and validation of an HPLC-UV-visible method for sunitinib quantification in human plasma.
Benoit Blanchet, Carole Saboureau, Anne Sophie Benichou, Bertrand Billemont, Fabrice Taieb, Stanislas Ropert, Alain Dauphin, François Goldwasser, Michel Tod. Clin Chim Acta 2009
Benoit Blanchet, Carole Saboureau, Anne Sophie Benichou, Bertrand Billemont, Fabrice Taieb, Stanislas Ropert, Alain Dauphin, François Goldwasser, Michel Tod. Clin Chim Acta 2009
20
Development of a rapid and sensitive LC-MS/MS assay for the determination of sorafenib in human plasma.
Lokesh Jain, Erin R Gardner, Jürgen Venitz, William Dahut, William D Figg. J Pharm Biomed Anal 2008
Lokesh Jain, Erin R Gardner, Jürgen Venitz, William Dahut, William D Figg. J Pharm Biomed Anal 2008
18
Prediction of free imatinib concentrations based on total plasma concentrations in patients with gastrointestinal stromal tumours.
Amina Haouala, Nicolas Widmer, Monia Guidi, Michael Montemurro, Serge Leyvraz, Thierry Buclin, Chin B Eap, Laurent A Decosterd, Chantal Csajka. Br J Clin Pharmacol 2013
Amina Haouala, Nicolas Widmer, Monia Guidi, Michael Montemurro, Serge Leyvraz, Thierry Buclin, Chin B Eap, Laurent A Decosterd, Chantal Csajka. Br J Clin Pharmacol 2013
28
Therapeutic drug monitoring in cancer--are we missing a trick?
Christophe Bardin, Gareth Veal, Angelo Paci, Etienne Chatelut, Alain Astier, Dominique Levêque, Nicolas Widmer, Jos Beijnen. Eur J Cancer 2014
Christophe Bardin, Gareth Veal, Angelo Paci, Etienne Chatelut, Alain Astier, Dominique Levêque, Nicolas Widmer, Jos Beijnen. Eur J Cancer 2014
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.