A citation-based method for searching scientific literature

Viviana I Pérez, Alex Bokov, Holly Van Remmen, James Mele, Qitao Ran, Yuji Ikeno, Arlan Richardson. Biochim Biophys Acta 2009
Times Cited: 393

List of co-cited articles
1284 articles co-cited >1

Times Cited
  Times     Co-cited

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013

Extension of murine life span by overexpression of catalase targeted to mitochondria.
Samuel E Schriner, Nancy J Linford, George M Martin, Piper Treuting, Charles E Ogburn, Mary Emond, Pinar E Coskun, Warren Ladiges, Norman Wolf, Holly Van Remmen,[...]. Science 2005

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011

Oxidative stress, caloric restriction, and aging.
R S Sohal, R Weindruch. Science 1996

The free radical theory of aging matures.
K B Beckman, B N Ames. Physiol Rev 1998

Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans.
Ryan Doonan, Joshua J McElwee, Filip Matthijssens, Glenda A Walker, Koen Houthoofd, Patricia Back, Andrea Matscheski, Jacques R Vanfleteren, David Gems. Genes Dev 2008

The biologic clock: the mitochondria?
D Harman. J Am Geriatr Soc 1972

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging.
G C Kujoth, A Hiona, T D Pugh, S Someya, K Panzer, S E Wohlgemuth, T Hofer, A Y Seo, R Sullivan, W A Jobling,[...]. Science 2005

Extending life span by increasing oxidative stress.
Michael Ristow, Sebastian Schmeisser. Free Radic Biol Med 2011

Rates of behavior and aging specified by mitochondrial function during development.
Andrew Dillin, Ao-Lin Hsu, Nuno Arantes-Oliveira, Joshua Lehrer-Graiwer, Honor Hsin, Andrew G Fraser, Ravi S Kamath, Julie Ahringer, Cynthia Kenyon. Science 2002

Geroscience: linking aging to chronic disease.
Brian K Kennedy, Shelley L Berger, Anne Brunet, Judith Campisi, Ana Maria Cuervo, Elissa S Epel, Claudio Franceschi, Gordon J Lithgow, Richard I Morimoto, Jeffrey E Pessin,[...]. Cell 2014

Extending healthy life span--from yeast to humans.
Luigi Fontana, Linda Partridge, Valter D Longo. Science 2010

The overexpression of major antioxidant enzymes does not extend the lifespan of mice.
Viviana I Pérez, Holly Van Remmen, Alex Bokov, Charles J Epstein, Jan Vijg, Arlan Richardson. Aging Cell 2009

High oxidative damage levels in the longest-living rodent, the naked mole-rat.
Blazej Andziak, Timothy P O'Connor, Wenbo Qi, Eric M DeWaal, Anson Pierce, Asish R Chaudhuri, Holly Van Remmen, Rochelle Buffenstein. Aging Cell 2006

Caloric restriction delays disease onset and mortality in rhesus monkeys.
Ricki J Colman, Rozalyn M Anderson, Sterling C Johnson, Erik K Kastman, Kristopher J Kosmatka, T Mark Beasley, David B Allison, Christina Cruzen, Heather A Simmons, Joseph W Kemnitz,[...]. Science 2009

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging.
Holly Van Remmen, Yuji Ikeno, Michelle Hamilton, Mohammad Pahlavani, Norman Wolf, Suzanne R Thorpe, Nathan L Alderson, John W Baynes, Charles J Epstein, Ting-Ting Huang,[...]. Physiol Genomics 2003

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.
Konrad T Howitz, Kevin J Bitterman, Haim Y Cohen, Dudley W Lamming, Siva Lavu, Jason G Wood, Robert E Zipkin, Phuong Chung, Anne Kisielewski, Li-Li Zhang,[...]. Nature 2003

The role of oxidative damage and stress in aging.
Alex Bokov, Asish Chaudhuri, Arlan Richardson. Mech Ageing Dev 2004

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Darren J Baker, Bennett G Childs, Matej Durik, Melinde E Wijers, Cynthia J Sieben, Jian Zhong, Rachel A Saltness, Karthik B Jeganathan, Grace Casaclang Verzosa, Abdulmohammad Pezeshki,[...]. Nature 2016

mTOR is a key modulator of ageing and age-related disease.
Simon C Johnson, Peter S Rabinovitch, Matt Kaeberlein. Nature 2013

Oxidative stress response and Nrf2 signaling in aging.
Hongqiao Zhang, Kelvin J A Davies, Henry Jay Forman. Free Radic Biol Med 2015

The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010

Trends in oxidative aging theories.
Florian L Muller, Michael S Lustgarten, Youngmok Jang, Arlan Richardson, Holly Van Remmen. Free Radic Biol Med 2007

When a theory of aging ages badly.
Jérôme Lapointe, Siegfried Hekimi. Cell Mol Life Sci 2010

Evolution of ageing.
T B Kirkwood. Nature 1977

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease.
Andreas Bender, Kim J Krishnan, Christopher M Morris, Geoffrey A Taylor, Amy K Reeve, Robert H Perry, Evelyn Jaros, Joshua S Hersheson, Joanne Betts, Thomas Klopstock,[...]. Nat Genet 2006

Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004

The genetics of ageing.
Cynthia J Kenyon. Nature 2010

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
David E Harrison, Randy Strong, Zelton Dave Sharp, James F Nelson, Clinton M Astle, Kevin Flurkey, Nancy L Nadon, J Erby Wilkinson, Krystyna Frenkel, Christy S Carter,[...]. Nature 2009

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.
T L Parkes, A J Elia, D Dickinson, A J Hilliker, J P Phillips, G L Boulianne. Nat Genet 1998

Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat.
Viviana I Pérez, Rochelle Buffenstein, Venkata Masamsetti, Shanique Leonard, Adam B Salmon, James Mele, Blazej Andziak, Ting Yang, Yael Edrey, Bertrand Friguet,[...]. Proc Natl Acad Sci U S A 2009

A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1-/- mice is correlated to increased cellular senescence.
Yiqiang Zhang, Archana Unnikrishnan, Sathyaseelan S Deepa, Yuhong Liu, Yan Li, Yuji Ikeno, Danuta Sosnowska, Holly Van Remmen, Arlan Richardson. Redox Biol 2017

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding, Nino Giorgadze, Allyson K Palmer, Yuji Ikeno, Gene B Hubbard, Marc Lenburg,[...]. Aging Cell 2015

A C. elegans mutant that lives twice as long as wild type.
C Kenyon, J Chang, E Gensch, A Rudner, R Tabtiang. Nature 1993

Life and death: metabolic rate, membrane composition, and life span of animals.
A J Hulbert, Reinald Pamplona, Rochelle Buffenstein, W A Buttemer. Physiol Rev 2007

Mitochondrial oxidative stress in aging and healthspan.
Dao-Fu Dai, Ying Ann Chiao, David J Marcinek, Hazel H Szeto, Peter S Rabinovitch. Longev Healthspan 2014

Endogenous hydrogen sulfide production is essential for dietary restriction benefits.
Christopher Hine, Eylul Harputlugil, Yue Zhang, Christoph Ruckenstuhl, Byung Cheon Lee, Lear Brace, Alban Longchamp, Jose H Treviño-Villarreal, Pedro Mejia, C Keith Ozaki,[...]. Cell 2015

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.
Laurent Mouchiroud, Riekelt H Houtkooper, Norman Moullan, Elena Katsyuba, Dongryeol Ryu, Carles Cantó, Adrienne Mottis, Young-Suk Jo, Mohan Viswanathan, Kristina Schoonjans,[...]. Cell 2013

Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.
Yiqiang Zhang, Yuji Ikeno, Wenbo Qi, Asish Chaudhuri, Yan Li, Alex Bokov, Suzanne R Thorpe, John W Baynes, Charles Epstein, Arlan Richardson,[...]. J Gerontol A Biol Sci Med Sci 2009

Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy.
Florian L Muller, Wook Song, Yuhong Liu, Asish Chaudhuri, Sandra Pieke-Dahl, Randy Strong, Ting-Ting Huang, Charles J Epstein, L Jackson Roberts, Marie Csete,[...]. Free Radic Biol Med 2006

Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases.
Claudio Franceschi, Judith Campisi. J Gerontol A Biol Sci Med Sci 2014

Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments.
Hongqiao Zhang, Honglei Liu, Kelvin J A Davies, Constantinos Sioutas, Caleb E Finch, Todd E Morgan, Henry Jay Forman. Free Radic Biol Med 2012

Mitochondria, oxidants, and aging.
Robert S Balaban, Shino Nemoto, Toren Finkel. Cell 2005

Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation.
Xiaolei Qiu, Katharine Brown, Matthew D Hirschey, Eric Verdin, Danica Chen. Cell Metab 2010

Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction.
Shinichi Someya, Wei Yu, William C Hallows, Jinze Xu, James M Vann, Christiaan Leeuwenburgh, Masaru Tanokura, John M Denu, Tomas A Prolla. Cell 2010

Understanding the odd science of aging.
Thomas B L Kirkwood. Cell 2005

Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.