A citation-based method for searching scientific literature

Gillian I Rice, Jacquelyn Bond, Aruna Asipu, Rebecca L Brunette, Iain W Manfield, Ian M Carr, Jonathan C Fuller, Richard M Jackson, Teresa Lamb, Tracy A Briggs, Manir Ali, Hannah Gornall, Lydia R Couthard, Alec Aeby, Simon P Attard-Montalto, Enrico Bertini, Christine Bodemer, Knut Brockmann, Louise A Brueton, Peter C Corry, Isabelle Desguerre, Elisa Fazzi, Angels Garcia Cazorla, Blanca Gener, Ben C J Hamel, Arvid Heiberg, Matthew Hunter, Marjo S van der Knaap, Ram Kumar, Lieven Lagae, Pierre G Landrieu, Charles M Lourenco, Daphna Marom, Michael F McDermott, William van der Merwe, Simona Orcesi, Julie S Prendiville, Magnhild Rasmussen, Stavit A Shalev, Doriette M Soler, Marwan Shinawi, Ronen Spiegel, Tiong Y Tan, Adeline Vanderver, Emma L Wakeling, Evangeline Wassmer, Elizabeth Whittaker, Pierre Lebon, Daniel B Stetson, David T Bonthron, Yanick J Crow. Nat Genet 2009
Times Cited: 489







List of co-cited articles
1459 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus.
Yanick J Crow, Bruce E Hayward, Rekha Parmar, Peter Robins, Andrea Leitch, Manir Ali, Deborah N Black, Hans van Bokhoven, Han G Brunner, Ben C Hamel,[...]. Nat Genet 2006
581
41

Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection.
Yanick J Crow, Andrea Leitch, Bruce E Hayward, Anna Garner, Rekha Parmar, Elen Griffith, Manir Ali, Colin Semple, Jean Aicardi, Riyana Babul-Hirji,[...]. Nat Genet 2006
490
40

SAMHD1 acts at stalled replication forks to prevent interferon induction.
Flavie Coquel, Maria-Joao Silva, Hervé Técher, Karina Zadorozhny, Sushma Sharma, Jadwiga Nieminuszczy, Clément Mettling, Elodie Dardillac, Antoine Barthe, Anne-Lyne Schmitz,[...]. Nature 2018
164
39

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature.
Gillian I Rice, Paul R Kasher, Gabriella M A Forte, Niamh M Mannion, Sam M Greenwood, Marcin Szynkiewicz, Jonathan E Dickerson, Sanjeev S Bhaskar, Massimiliano Zampini, Tracy A Briggs,[...]. Nat Genet 2012
484
38

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.
David C Goldstone, Valerie Ennis-Adeniran, Joseph J Hedden, Harriet C T Groom, Gillian I Rice, Evangelos Christodoulou, Philip A Walker, Geoff Kelly, Lesley F Haire, Melvyn W Yap,[...]. Nature 2011
565
36

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx.
Nadine Laguette, Bijan Sobhian, Nicoletta Casartelli, Mathieu Ringeard, Christine Chable-Bessia, Emmanuel Ségéral, Ahmad Yatim, Stéphane Emiliani, Olivier Schwartz, Monsef Benkirane. Nature 2011
33

Aicardi-Goutières syndrome and the type I interferonopathies.
Yanick J Crow, Nicolas Manel. Nat Rev Immunol 2015
470
32

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates.
Hichem Lahouassa, Waaqo Daddacha, Henning Hofmann, Diana Ayinde, Eric C Logue, Loïc Dragin, Nicolin Bloch, Claire Maudet, Matthieu Bertrand, Thomas Gramberg,[...]. Nat Immunol 2012
582
30

Trex1 prevents cell-intrinsic initiation of autoimmunity.
Daniel B Stetson, Joan S Ko, Thierry Heidmann, Ruslan Medzhitov. Cell 2008
832
30

Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling.
Gillian I Rice, Yoandris Del Toro Duany, Emma M Jenkinson, Gabriella Ma Forte, Beverley H Anderson, Giada Ariaudo, Brigitte Bader-Meunier, Eileen M Baildam, Roberta Battini, Michael W Beresford,[...]. Nat Genet 2014
358
29

Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1.
Yanick J Crow, Diana S Chase, Johanna Lowenstein Schmidt, Marcin Szynkiewicz, Gabriella M A Forte, Hannah L Gornall, Anthony Oojageer, Beverley Anderson, Amy Pizzino, Guy Helman,[...]. Am J Med Genet A 2015
306
29

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein.
Kasia Hrecka, Caili Hao, Magda Gierszewska, Selene K Swanson, Malgorzata Kesik-Brodacka, Smita Srivastava, Laurence Florens, Michael P Washburn, Jacek Skowronski. Nature 2011
852
28

SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.
Waaqo Daddacha, Allyson E Koyen, Amanda J Bastien, PamelaSara E Head, Vishal R Dhere, Geraldine N Nabeta, Erin C Connolly, Erica Werner, Matthew Z Madden, Michele B Daly,[...]. Cell Rep 2017
85
31

SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.
Ruth Clifford, Tania Louis, Pauline Robbe, Sam Ackroyd, Adam Burns, Adele T Timbs, Glen Wright Colopy, Helene Dreau, Francois Sigaux, Jean Gabriel Judde,[...]. Blood 2014
146
25

The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells.
Elisa Franzolin, Giovanna Pontarin, Chiara Rampazzo, Cristina Miazzi, Paola Ferraro, Elisa Palumbo, Peter Reichard, Vera Bianchi. Proc Natl Acad Sci U S A 2013
156
24

Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response.
Rayk Behrendt, Tina Schumann, Alexander Gerbaulet, Laura A Nguyen, Nadja Schubert, Dimitra Alexopoulou, Ursula Berka, Stefan Lienenklaus, Katrin Peschke, Kathrin Gibbert,[...]. Cell Rep 2013
117
24

Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance.
Matilda Rentoft, Kristoffer Lindell, Phong Tran, Anna Lena Chabes, Robert J Buckland, Danielle L Watt, Lisette Marjavaara, Anna Karin Nilsson, Beatrice Melin, Johan Trygg,[...]. Proc Natl Acad Sci U S A 2016
68
32



Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.
Alexandra Cribier, Benjamin Descours, Ana Luiza Chaves Valadão, Nadine Laguette, Monsef Benkirane. Cell Rep 2013
274
21

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
21

Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study.
Gillian I Rice, Gabriella M A Forte, Marcin Szynkiewicz, Diana S Chase, Alec Aeby, Mohamed S Abdel-Hamid, Sam Ackroyd, Rebecca Allcock, Kathryn M Bailey, Umberto Balottin,[...]. Lancet Neurol 2013
239
20

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.
Hanna-Mari Baldauf, Xiaoyu Pan, Elina Erikson, Sarah Schmidt, Waaqo Daddacha, Manja Burggraf, Kristina Schenkova, Ina Ambiel, Guido Wabnitz, Thomas Gramberg,[...]. Nat Med 2012
430
20

The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation.
Tommy E White, Alberto Brandariz-Nuñez, Jose Carlos Valle-Casuso, Sarah Amie, Laura Anh Nguyen, Baek Kim, Marina Tuzova, Felipe Diaz-Griffero. Cell Host Microbe 2013
223
19

SAMHD1-dependent retroviral control and escape in mice.
Jan Rehwinkel, Jonathan Maelfait, Anne Bridgeman, Rachel Rigby, Bruce Hayward, Rachel A Liberatore, Paul D Bieniasz, Greg J Towers, Luis F Moita, Yanick J Crow,[...]. EMBO J 2013
118
19

Activated STING in a vascular and pulmonary syndrome.
Y Liu, A A Jesus, B Marrero, D Yang, S E Ramsey, G A Montealegre Sanchez, K Tenbrock, H Wittkowski, O Y Jones, H S Kuehn,[...]. N Engl J Med 2014
666
19

Reverse-Transcriptase Inhibitors in the Aicardi–Goutières Syndrome
Gillian I Rice, Candice Meyzer, Naïm Bouazza, Marie Hully, Nathalie Boddaert, Michaela Semeraro, Leo A H Zeef, Flore Rozenberg, Vincent Bondet, Darragh Duffy,[...]. N Engl J Med 2018
59
30

RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.
Vladislav Pokatayev, Naushaba Hasin, Hyongi Chon, Susana M Cerritelli, Kiran Sakhuja, Jerrold M Ward, H Douglas Morris, Nan Yan, Robert J Crouch. J Exp Med 2016
127
18

cGAS surveillance of micronuclei links genome instability to innate immunity.
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
628
17


Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutières syndrome-related SAMHD1.
Ke Zhao, Juan Du, Xue Han, John L Goodier, Peng Li, Xiaohong Zhou, Wei Wei, Sean L Evans, Linzhang Li, Wenyan Zhang,[...]. Cell Rep 2013
140
17

Mechanism of allosteric activation of SAMHD1 by dGTP.
Xiaoyun Ji, Ying Wu, Junpeng Yan, Jennifer Mehrens, Haitao Yang, Maria DeLucia, Caili Hao, Angela M Gronenborn, Jacek Skowronski, Jinwoo Ahn,[...]. Nat Struct Mol Biol 2013
97
16

Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells.
Joseph A Hollenbaugh, Peter Gee, Jonathon Baker, Michele B Daly, Sarah M Amie, Jessica Tate, Natsumi Kasai, Yuka Kanemura, Dong-Hyun Kim, Brian M Ward,[...]. PLoS Pathog 2013
118
16

Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.
Karen J Mackenzie, Paula Carroll, Laura Lettice, Žygimantė Tarnauskaitė, Kaalak Reddy, Flora Dix, Ailsa Revuelta, Erika Abbondati, Rachel E Rigby, Björn Rabe,[...]. EMBO J 2016
135
16

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.
Martin A M Reijns, Björn Rabe, Rachel E Rigby, Pleasantine Mill, Katy R Astell, Laura A Lettice, Shelagh Boyle, Andrea Leitch, Margaret Keighren, Fiona Kilanowski,[...]. Cell 2012
301
16

SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells.
Serena Bonifati, Michele B Daly, Corine St Gelais, Sun Hee Kim, Joseph A Hollenbaugh, Caitlin Shepard, Edward M Kennedy, Dong-Hyun Kim, Raymond F Schinazi, Baek Kim,[...]. Virology 2016
54
27

Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1.
Jonathan Maelfait, Anne Bridgeman, Adel Benlahrech, Chiara Cursi, Jan Rehwinkel. Cell Rep 2016
66
22

SAMHD1 prevents autoimmunity by maintaining genome stability.
Stefanie Kretschmer, Christine Wolf, Nadja König, Wolfgang Staroske, Jochen Guck, Martin Häusler, Hella Luksch, Laura A Nguyen, Baek Kim, Dimitra Alexopoulou,[...]. Ann Rheum Dis 2015
100
15

JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies.
Gina A Montealegre Sanchez, Adam Reinhardt, Suzanne Ramsey, Helmut Wittkowski, Philip J Hashkes, Yackov Berkun, Susanne Schalm, Sara Murias, Jason A Dare, Diane Brown,[...]. J Clin Invest 2018
225
15

Structural basis of cellular dNTP regulation by SAMHD1.
Xiaoyun Ji, Chenxiang Tang, Qi Zhao, Wei Wang, Yong Xiong. Proc Natl Acad Sci U S A 2014
80
17

Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome.
Yoong Wearn Lim, Lionel A Sanz, Xiaoqin Xu, Stella R Hartono, Frédéric Chédin. Elife 2015
95
14


Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation.
Charles A Thomas, Leon Tejwani, Cleber A Trujillo, Priscilla D Negraes, Roberto H Herai, Pinar Mesci, Angela Macia, Yanick J Crow, Alysson R Muotri. Cell Stem Cell 2017
134
14

Restriction of diverse retroviruses by SAMHD1.
Thomas Gramberg, Tanja Kahle, Nicolin Bloch, Sabine Wittmann, Erik Müllers, Waaqo Daddacha, Henning Hofmann, Baek Kim, Dirk Lindemann, Nathaniel R Landau. Retrovirology 2013
110
13

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction.
Jeongmin Ryoo, Jongsu Choi, Changhoon Oh, Sungchul Kim, Minji Seo, Seok-Young Kim, Daekwan Seo, Jongkyu Kim, Tommy E White, Alberto Brandariz-Nuñez,[...]. Nat Med 2014
202
13

SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways.
Shuliang Chen, Serena Bonifati, Zhihua Qin, Corine St Gelais, Karthik M Kodigepalli, Bradley S Barrett, Sun Hee Kim, Jenna M Antonucci, Katherine J Ladner, Olga Buzovetsky,[...]. Proc Natl Acad Sci U S A 2018
50
26

Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.
Natalia Beloglazova, Robert Flick, Anatoli Tchigvintsev, Greg Brown, Ana Popovic, Boguslaw Nocek, Alexander F Yakunin. J Biol Chem 2013
160
13

SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.
Constanze Schneider, Thomas Oellerich, Hanna-Mari Baldauf, Sarah-Marie Schwarz, Dominique Thomas, Robert Flick, Hanibal Bohnenberger, Lars Kaderali, Lena Stegmann, Anjali Cremer,[...]. Nat Med 2017
68
19

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.
Daxing Gao, Tuo Li, Xiao-Dong Li, Xiang Chen, Quan-Zhen Li, Mary Wight-Carter, Zhijian J Chen. Proc Natl Acad Sci U S A 2015
321
13

Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome.
Elizabeth E Gray, Piper M Treuting, Joshua J Woodward, Daniel B Stetson. J Immunol 2015
191
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.