A citation-based method for searching scientific literature

Martin Biel, Christian Wahl-Schott, Stylianos Michalakis, Xiangang Zong. Physiol Rev 2009
Times Cited: 660







List of co-cited articles
734 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Hyperpolarization-activated cation currents: from molecules to physiological function.
Richard B Robinson, Steven A Siegelbaum. Annu Rev Physiol 2003
829
20

A family of hyperpolarization-activated mammalian cation channels.
A Ludwig, X Zong, M Jeglitsch, F Hofmann, M Biel. Nature 1998
736
16


Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2.
Andreas Ludwig, Thomas Budde, Juliane Stieber, Sven Moosmang, Christian Wahl, Knut Holthoff, Anke Langebartels, Carsten Wotjak, Thomas Munsch, Xiangang Zong,[...]. EMBO J 2003
384
14

Molecular mechanism of cAMP modulation of HCN pacemaker channels.
B J Wainger, M DeGennaro, B Santoro, S A Siegelbaum, G R Tibbs. Nature 2001
364
14

Cardiac and neuronal HCN channelopathies.
Ilaria Rivolta, Anna Binda, Alessio Masi, Jacopo C DiFrancesco. Pflugers Arch 2020
24
54

HCN1 mutation spectrum: from neonatal epileptic encephalopathy to benign generalized epilepsy and beyond.
Carla Marini, Alessandro Porro, Agnès Rastetter, Carine Dalle, Ilaria Rivolta, Daniel Bauer, Renske Oegema, Caroline Nava, Elena Parrini, Davide Mei,[...]. Brain 2018
47
25


Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites.
Nicholas P Poolos, Michele Migliore, Daniel Johnston. Nat Neurosci 2002
309
12


Neurophysiology of HCN channels: from cellular functions to multiple regulations.
Chao He, Fang Chen, Bo Li, Zhian Hu. Prog Neurobiol 2014
197
11


De novo mutations in HCN1 cause early infantile epileptic encephalopathy.
Caroline Nava, Carine Dalle, Agnès Rastetter, Pasquale Striano, Carolien G F de Kovel, Rima Nabbout, Claude Cancès, Dorothée Ville, Eva H Brilstra, Giuseppe Gobbi,[...]. Nat Genet 2014
131
10

Structures of the Human HCN1 Hyperpolarization-Activated Channel.
Chia-Hsueh Lee, Roderick MacKinnon. Cell 2017
186
10

The Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels: from Biophysics to Pharmacology of a Unique Family of Ion Channels.
Laura Sartiani, Guido Mannaioni, Alessio Masi, Maria Novella Romanelli, Elisabetta Cerbai. Pharmacol Rev 2017
61
16

How does adrenaline accelerate the heart?
H F Brown, D DiFrancesco, S J Noble. Nature 1979
394
10


Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain.
B Santoro, D T Liu, H Yao, D Bartsch, E R Kandel, S A Siegelbaum, G R Tibbs. Cell 1998
557
9

HCN channels: function and clinical implications.
Eduardo E Benarroch. Neurology 2013
126
9

A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neurons.
Matthew F Nolan, Gaël Malleret, Josh T Dudman, Derek L Buhl, Bina Santoro, Emma Gibbs, Svetlana Vronskaya, György Buzsáki, Steven A Siegelbaum, Eric R Kandel,[...]. Cell 2004
354
9

The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart.
Juliane Stieber, Stefan Herrmann, Susanne Feil, Jana Löster, Robert Feil, Martin Biel, Franz Hofmann, Andreas Ludwig. Proc Natl Acad Sci U S A 2003
335
9

Exploring HCN channels as novel drug targets.
Otilia Postea, Martin Biel. Nat Rev Drug Discov 2011
146
9

ZD 7288 inhibits T-type calcium current in rat hippocampal pyramidal cells.
J L Sánchez-Alonso, J V Halliwell, A Colino. Neurosci Lett 2008
68
13

The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells.
Matthew F Nolan, Gaël Malleret, Ka Hung Lee, Emma Gibbs, Joshua T Dudman, Bina Santoro, Deqi Yin, Richard F Thompson, Steven A Siegelbaum, Eric R Kandel,[...]. Cell 2003
236
8


HCN3 contributes to the ventricular action potential waveform in the murine heart.
Stefanie Fenske, Robert Mader, Andreas Scharr, Christos Paparizos, Xiaochun Cao-Ehlker, Stylianos Michalakis, Lior Shaltiel, Martha Weidinger, Juliane Stieber, Susanne Feil,[...]. Circ Res 2011
56
12


Heteromeric HCN1-HCN4 channels: a comparison with native pacemaker channels from the rabbit sinoatrial node.
Claudia Altomare, Benedetta Terragni, Chiara Brioschi, Raffaella Milanesi, Cinzia Pagliuca, Carlo Viscomi, Anna Moroni, Mirko Baruscotti, Dario DiFrancesco. J Physiol 2003
162
7

HCN2 ion channels play a central role in inflammatory and neuropathic pain.
Edward C Emery, Gareth T Young, Esther M Berrocoso, Lubin Chen, Peter A McNaughton. Science 2011
222
7

Presynaptic HCN1 channels regulate Cav3.2 activity and neurotransmission at select cortical synapses.
Zhuo Huang, Rafael Lujan, Ivan Kadurin, Victor N Uebele, John J Renger, Annette C Dolphin, Mala M Shah. Nat Neurosci 2011
112
7

Alternatively spliced isoforms of TRIP8b differentially control h channel trafficking and function.
Alan S Lewis, Emily Schwartz, C Savio Chan, Yoav Noam, Minyoung Shin, Wytse J Wadman, D James Surmeier, Tallie Z Baram, Robert L Macdonald, Dane M Chetkovich. J Neurosci 2009
107
7

Cloning and localization of the hyperpolarization-activated cyclic nucleotide-gated channel family in rat brain.
L M Monteggia, A J Eisch, M D Tang, L K Kaczmarek, E J Nestler. Brain Res Mol Brain Res 2000
177
7

A novel de novo HCN1 loss-of-function mutation in genetic generalized epilepsy causing increased neuronal excitability.
Mattia Bonzanni, Jacopo C DiFrancesco, Raffaella Milanesi, Giulia Campostrini, Barbara Castellotti, Annalisa Bucchi, Mirko Baruscotti, Carlo Ferrarese, Silvana Franceschetti, Laura Canafoglia,[...]. Neurobiol Dis 2018
24
29

Gabapentin Modulates HCN4 Channel Voltage-Dependence.
Han-Shen Tae, Kelly M Smith, A Marie Phillips, Kieran A Boyle, Melody Li, Ian C Forster, Robert J Hatch, Robert Richardson, David I Hughes, Brett A Graham,[...]. Front Pharmacol 2017
19
36

HCN Channels Modulators: The Need for Selectivity.
Maria Novella Romanelli, Laura Sartiani, Alessio Masi, Guido Mannaioni, Dina Manetti, Alessandro Mugelli, Elisabetta Cerbai. Curr Top Med Chem 2016
39
17

Structural basis for modulation and agonist specificity of HCN pacemaker channels.
William N Zagotta, Nelson B Olivier, Kevin D Black, Edgar C Young, Rich Olson, Eric Gouaux. Nature 2003
446
7


Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study.
Karl Swedberg, Michel Komajda, Michael Böhm, Jeffrey S Borer, Ian Ford, Ariane Dubost-Brama, Guy Lerebours, Luigi Tavazzi. Lancet 2010
6

Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis.
Zhuo Huang, Matthew C Walker, Mala M Shah. J Neurosci 2009
118
6

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4.
Mirko Baruscotti, Annalisa Bucchi, Carlo Viscomi, Giacomo Mandelli, Giacomo Consalez, Tomaso Gnecchi-Rusconi, Nicola Montano, Karina Rabello Casali, Stefano Micheloni, Andrea Barbuti,[...]. Proc Natl Acad Sci U S A 2011
196
6

Subthreshold membrane resonance in neocortical neurons.
B Hutcheon, R M Miura, E Puil. J Neurophysiol 1996
190
6




Testing broad-spectrum and isoform-preferring HCN channel blockers for anticonvulsant properties in mice.
Qays Kharouf, Paulo Pinares-Garcia, M Novella Romanelli, Christopher A Reid. Epilepsy Res 2020
7
85

HCN Channels: New Therapeutic Targets for Pain Treatment.
David Ramírez, Rafael Zúñiga, Guierdy Concha, Leandro Zúñiga. Molecules 2018
13
46


Polarized and compartment-dependent distribution of HCN1 in pyramidal cell dendrites.
Andrea Lörincz, Takuya Notomi, Gábor Tamás, Ryuichi Shigemoto, Zoltan Nusser. Nat Neurosci 2002
330
6

Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function.
Kendall M Foote, Kyle A Lyman, Ye Han, Ioannis E Michailidis, Robert J Heuermann, Danielle Mandikian, James S Trimmer, Geoffrey T Swanson, Dane M Chetkovich. J Biol Chem 2019
11
54


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.