Mengqi Chen, Ralph N Martins, Michael Lardelli. J Alzheimers Dis 2009
Times Cited: 32
Times Cited: 32
Times Cited
Times Co-cited
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A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation.
Dominik Paquet, Ratan Bhat, Astrid Sydow, Eva-Maria Mandelkow, Stefan Berg, Sven Hellberg, Johanna Fälting, Martin Distel, Reinhard W Köster, Bettina Schmid,[...]. J Clin Invest 2009
Dominik Paquet, Ratan Bhat, Astrid Sydow, Eva-Maria Mandelkow, Stefan Berg, Sven Hellberg, Johanna Fälting, Martin Distel, Reinhard W Köster, Bettina Schmid,[...]. J Clin Invest 2009
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Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene.
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Transgenic zebrafish model of neurodegeneration.
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Identification of a second presenilin gene in zebrafish with similarity to the human Alzheimer's disease gene presenilin2.
Casper Groth, Svanhild Nornes, Rosa McCarty, Richard Tamme, Michael Lardelli. Dev Genes Evol 2002
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Distinct expression patterns of two zebrafish homologues of the human APP gene during embryonic development.
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Zebrafish (Danio rerio) presenilin promotes aberrant amyloid beta-peptide production and requires a critical aspartate residue for its function in amyloidogenesis.
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Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss.
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Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17.
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Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain.
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The adult central nervous cholinergic system of a neurogenetic model animal, the zebrafish Danio rerio.
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A protein factor essential for microtubule assembly.
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Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.
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Mutation in the tau gene in familial multiple system tauopathy with presenile dementia.
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Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.
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Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization.
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Connections of the ventral telencephalon (subpallium) in the zebrafish (Danio rerio).
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Identification of a functional transposase of the Tol2 element, an Ac-like element from the Japanese medaka fish, and its transposition in the zebrafish germ lineage.
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In vivo drug discovery in the zebrafish.
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18
Identification and characterization of the Drosophila tau homolog.
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18
Tau suppression in a neurodegenerative mouse model improves memory function.
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Amyloid precursor protein is required for convergent-extension movements during Zebrafish development.
Powrnima Joshi, Jennifer O Liang, Kristine DiMonte, John Sullivan, Sanjay W Pimplikar. Dev Biol 2009
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18
Developmental control of Presenilin1 expression, endoproteolysis, and interaction in zebrafish embryos.
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Independent and cooperative action of Psen2 with Psen1 in zebrafish embryos.
Svanhild Nornes, Morgan Newman, Simon Wells, Giuseppe Verdile, Ralph N Martins, Michael Lardelli. Exp Cell Res 2009
Svanhild Nornes, Morgan Newman, Simon Wells, Giuseppe Verdile, Ralph N Martins, Michael Lardelli. Exp Cell Res 2009
22
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.
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Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles.
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18
Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy.
Brian C Kraemer, Bin Zhang, James B Leverenz, James H Thomas, John Q Trojanowski, Gerard D Schellenberg. Proc Natl Acad Sci U S A 2003
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Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform.
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18
Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila.
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18
Animal models of human disease: zebrafish swim into view.
Graham J Lieschke, Peter D Currie. Nat Rev Genet 2007
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Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein.
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18
Multiple signaling factors and drugs alleviate neuronal death induced by expression of human and zebrafish tau proteins in vivo.
Bo-Kai Wu, Rey-Yue Yuan, Huang-Wei Lien, Chin-Chun Hung, Pung-Pung Hwang, Rita Pei-Yeh Chen, Chun-Che Chang, Yung-Feng Liao, Chang-Jen Huang. J Biomed Sci 2016
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46
A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction.
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Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo.
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Zebrafish DJ-1 is evolutionarily conserved and expressed in dopaminergic neurons.
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Neurochemical and behavioural changes in zebrafish Danio rerio after systemic administration of 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
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CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo.
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p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease.
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Identification of anti-prion compounds as efficient inhibitors of polyglutamine protein aggregation in a zebrafish model.
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Functional and developmental analysis of the blood-brain barrier in zebrafish.
Jae-Yeon Jeong, Hyouk-Bum Kwon, Jong-Chan Ahn, Dongmin Kang, Seung-Hae Kwon, Jeong Ae Park, Kyu-Won Kim. Brain Res Bull 2008
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Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio).
Laura Flinn, Heather Mortiboys, Katrin Volkmann, Reinhard W Köster, Phillip W Ingham, Oliver Bandmann. Brain 2009
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Huntingtin-deficient zebrafish exhibit defects in iron utilization and development.
Amanda L Lumsden, Tanya L Henshall, Sonia Dayan, Michael T Lardelli, Robert I Richards. Hum Mol Genet 2007
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Developmentally regulated expression of specific tau sequences.
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PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans.
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ptl-1, a Caenorhabditis elegans gene whose products are homologous to the tau microtubule-associated proteins.
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Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons.
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An evolutionary interpretation of teleostean forebrain anatomy.
Thomas Mueller, Mario F Wullimann. Brain Behav Evol 2009
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Association of an extended haplotype in the tau gene with progressive supranuclear palsy.
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Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils.
J Götz, F Chen, J van Dorpe, R M Nitsch. Science 2001
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15
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