Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
Times Cited: 636
Times Cited: 636
Times Cited
Times Co-cited
Similarity
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity.
Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I R Petalcorin, Hao Ding, Simon J Boulton. Cell 2012
Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I R Petalcorin, Hao Ding, Simon J Boulton. Cell 2012
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Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
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Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
25
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.
Claus M Azzalin, Patrick Reichenbach, Lela Khoriauli, Elena Giulotto, Joachim Lingner. Science 2007
Claus M Azzalin, Patrick Reichenbach, Lela Khoriauli, Elena Giulotto, Joachim Lingner. Science 2007
23
Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation.
Ylli Doksani, John Y Wu, Titia de Lange, Xiaowei Zhuang. Cell 2013
Ylli Doksani, John Y Wu, Titia de Lange, Xiaowei Zhuang. Cell 2013
21
RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells.
Rajika Arora, Yongwoo Lee, Harry Wischnewski, Catherine M Brun, Tobias Schwarz, Claus M Azzalin. Nat Commun 2014
Rajika Arora, Yongwoo Lee, Harry Wischnewski, Catherine M Brun, Tobias Schwarz, Claus M Azzalin. Nat Commun 2014
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TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.
Michal Zimmermann, Tatsuya Kibe, Shaheen Kabir, Titia de Lange. Genes Dev 2014
Michal Zimmermann, Tatsuya Kibe, Shaheen Kabir, Titia de Lange. Genes Dev 2014
20
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.
Paula Martínez, Maria Thanasoula, Purificación Muñoz, Chunyan Liao, Agueda Tejera, Carolyn McNees, Juana M Flores, Oscar Fernández-Capetillo, Madalena Tarsounas, Maria A Blasco. Genes Dev 2009
Paula Martínez, Maria Thanasoula, Purificación Muñoz, Chunyan Liao, Agueda Tejera, Carolyn McNees, Juana M Flores, Oscar Fernández-Capetillo, Madalena Tarsounas, Maria A Blasco. Genes Dev 2009
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Alternative lengthening of telomeres: models, mechanisms and implications.
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
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Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
Eros Lazzerini Denchi, Titia de Lange. Nature 2007
Eros Lazzerini Denchi, Titia de Lange. Nature 2007
19
Break-induced telomere synthesis underlies alternative telomere maintenance.
Robert L Dilley, Priyanka Verma, Nam Woo Cho, Harrison D Winters, Anne R Wondisford, Roger A Greenberg. Nature 2016
Robert L Dilley, Priyanka Verma, Nam Woo Cho, Harrison D Winters, Anne R Wondisford, Roger A Greenberg. Nature 2016
19
DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.
Giulia B Celli, Titia de Lange. Nat Cell Biol 2005
Giulia B Celli, Titia de Lange. Nat Cell Biol 2005
16
Removal of shelterin reveals the telomere end-protection problem.
Agnel Sfeir, Titia de Lange. Science 2012
Agnel Sfeir, Titia de Lange. Science 2012
16
16
TRF2 protects human telomeres from end-to-end fusions.
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
15
Alternative Lengthening of Telomeres Mediated by Mitotic DNA Synthesis Engages Break-Induced Replication Processes.
Jaewon Min, Woodring E Wright, Jerry W Shay. Mol Cell Biol 2017
Jaewon Min, Woodring E Wright, Jerry W Shay. Mol Cell Biol 2017
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Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST.
Peng Wu, Hiroyuki Takai, Titia de Lange. Cell 2012
Peng Wu, Hiroyuki Takai, Titia de Lange. Cell 2012
14
RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication.
Jean-Baptiste Vannier, Sumit Sandhu, Mark I R Petalcorin, Xiaoli Wu, Zinnatun Nabi, Hao Ding, Simon J Boulton. Science 2013
Jean-Baptiste Vannier, Sumit Sandhu, Mark I R Petalcorin, Xiaoli Wu, Zinnatun Nabi, Hao Ding, Simon J Boulton. Science 2013
14
Telomere Loop Dynamics in Chromosome End Protection.
David Van Ly, Ronnie Ren Jie Low, Sonja Frölich, Tara K Bartolec, Georgia R Kafer, Hilda A Pickett, Katharina Gaus, Anthony J Cesare. Mol Cell 2018
David Van Ly, Ronnie Ren Jie Low, Sonja Frölich, Tara K Bartolec, Georgia R Kafer, Hilda A Pickett, Katharina Gaus, Anthony J Cesare. Mol Cell 2018
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Telomere protection by TPP1/POT1 requires tethering to TIN2.
Kaori K Takai, Tatsuya Kibe, Jill R Donigian, David Frescas, Titia de Lange. Mol Cell 2011
Kaori K Takai, Tatsuya Kibe, Jill R Donigian, David Frescas, Titia de Lange. Mol Cell 2011
13
Pot1, the putative telomere end-binding protein in fission yeast and humans.
P Baumann, T R Cech. Science 2001
P Baumann, T R Cech. Science 2001
13
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II.
Stefan Schoeftner, Maria A Blasco. Nat Cell Biol 2008
Stefan Schoeftner, Maria A Blasco. Nat Cell Biol 2008
13
DNA damage foci at dysfunctional telomeres.
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
13
TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding.
Grzegorz Sarek, Jean-Baptiste Vannier, Stephanie Panier, John H J Petrini, Simon J Boulton. Mol Cell 2015
Grzegorz Sarek, Jean-Baptiste Vannier, Stephanie Panier, John H J Petrini, Simon J Boulton. Mol Cell 2015
14
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2.
J Karlseder, D Broccoli, Y Dai, S Hardy, T de Lange. Science 1999
J Karlseder, D Broccoli, Y Dai, S Hardy, T de Lange. Science 1999
12
Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.
Anthony J Cesare, Zeenia Kaul, Scott B Cohen, Christine E Napier, Hilda A Pickett, Axel A Neumann, Roger R Reddel. Nat Struct Mol Biol 2009
Anthony J Cesare, Zeenia Kaul, Scott B Cohen, Christine E Napier, Hilda A Pickett, Axel A Neumann, Roger R Reddel. Nat Struct Mol Biol 2009
12
Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways.
Jia-Min Zhang, Tribhuwan Yadav, Jian Ouyang, Li Lan, Lee Zou. Cell Rep 2019
Jia-Min Zhang, Tribhuwan Yadav, Jian Ouyang, Li Lan, Lee Zou. Cell Rep 2019
14
Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
C B Harley, A B Futcher, C W Greider. Nature 1990
12
Interchromosomal homology searches drive directional ALT telomere movement and synapsis.
Nam Woo Cho, Robert L Dilley, Michael A Lampson, Roger A Greenberg. Cell 2014
Nam Woo Cho, Robert L Dilley, Michael A Lampson, Roger A Greenberg. Cell 2014
12
Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal.
Agnel Sfeir, Shaheen Kabir, Megan van Overbeek, Giulia B Celli, Titia de Lange. Science 2010
Agnel Sfeir, Shaheen Kabir, Megan van Overbeek, Giulia B Celli, Titia de Lange. Science 2010
11
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex.
Jeffrey Zheng-Sheng Ye, Dirk Hockemeyer, Andrew N Krutchinsky, Diego Loayza, Sarah M Hooper, Brian T Chait, Titia de Lange. Genes Dev 2004
Jeffrey Zheng-Sheng Ye, Dirk Hockemeyer, Andrew N Krutchinsky, Diego Loayza, Sarah M Hooper, Brian T Chait, Titia de Lange. Genes Dev 2004
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Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe.
Pol Margalef, Panagiotis Kotsantis, Valerie Borel, Roberto Bellelli, Stephanie Panier, Simon J Boulton. Cell 2018
Pol Margalef, Panagiotis Kotsantis, Valerie Borel, Roberto Bellelli, Stephanie Panier, Simon J Boulton. Cell 2018
22
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines.
T M Bryan, A Englezou, L Dalla-Pozza, M A Dunham, R R Reddel. Nat Med 1997
T M Bryan, A Englezou, L Dalla-Pozza, M A Dunham, R R Reddel. Nat Med 1997
11
DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity.
Jeremy D Henson, Ying Cao, Lily I Huschtscha, Andy C Chang, Amy Y M Au, Hilda A Pickett, Roger R Reddel. Nat Biotechnol 2009
Jeremy D Henson, Ying Cao, Lily I Huschtscha, Andy C Chang, Amy Y M Au, Hilda A Pickett, Roger R Reddel. Nat Biotechnol 2009
11
Telomere Length Determines TERRA and R-Loop Regulation through the Cell Cycle.
Marco Graf, Diego Bonetti, Arianna Lockhart, Kamar Serhal, Vanessa Kellner, André Maicher, Pascale Jolivet, Maria Teresa Teixeira, Brian Luke. Cell 2017
Marco Graf, Diego Bonetti, Arianna Lockhart, Kamar Serhal, Vanessa Kellner, André Maicher, Pascale Jolivet, Maria Teresa Teixeira, Brian Luke. Cell 2017
11
PTOP interacts with POT1 and regulates its localization to telomeres.
Dan Liu, Amin Safari, Matthew S O'Connor, Doug W Chan, Andrew Laegeler, Jun Qin, Zhou Songyang. Nat Cell Biol 2004
Dan Liu, Amin Safari, Matthew S O'Connor, Doug W Chan, Andrew Laegeler, Jun Qin, Zhou Songyang. Nat Cell Biol 2004
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Control of telomere length by the human telomeric protein TRF1.
B van Steensel, T de Lange. Nature 1997
B van Steensel, T de Lange. Nature 1997
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Homologous recombination generates T-loop-sized deletions at human telomeres.
Richard C Wang, Agata Smogorzewska, Titia de Lange. Cell 2004
Richard C Wang, Agata Smogorzewska, Titia de Lange. Cell 2004
10
TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection.
Delphine Benarroch-Popivker, Sabrina Pisano, Aaron Mendez-Bermudez, Liudmyla Lototska, Parminder Kaur, Serge Bauwens, Nadir Djerbi, Chrysa M Latrick, Vincent Fraisier, Bei Pei,[...]. Mol Cell 2016
Delphine Benarroch-Popivker, Sabrina Pisano, Aaron Mendez-Bermudez, Liudmyla Lototska, Parminder Kaur, Serge Bauwens, Nadir Djerbi, Chrysa M Latrick, Vincent Fraisier, Bei Pei,[...]. Mol Cell 2016
12
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2.
D Broccoli, A Smogorzewska, L Chong, T de Lange. Nat Genet 1997
D Broccoli, A Smogorzewska, L Chong, T de Lange. Nat Genet 1997
10
Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis.
Alexandra M Pinzaru, Robert A Hom, Angela Beal, Aaron F Phillips, Eric Ni, Timothy Cardozo, Nidhi Nair, Jaehyuk Choi, Deborah S Wuttke, Agnel Sfeir,[...]. Cell Rep 2016
Alexandra M Pinzaru, Robert A Hom, Angela Beal, Aaron F Phillips, Eric Ni, Timothy Cardozo, Nidhi Nair, Jaehyuk Choi, Deborah S Wuttke, Agnel Sfeir,[...]. Cell Rep 2016
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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
C W Greider, E H Blackburn. Cell 1985
C W Greider, E H Blackburn. Cell 1985
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TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres.
Zhong Deng, Julie Norseen, Andreas Wiedmer, Harold Riethman, Paul M Lieberman. Mol Cell 2009
Zhong Deng, Julie Norseen, Andreas Wiedmer, Harold Riethman, Paul M Lieberman. Mol Cell 2009
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Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.
Arthur J Zaug, Elaine R Podell, Thomas R Cech. Proc Natl Acad Sci U S A 2005
Arthur J Zaug, Elaine R Podell, Thomas R Cech. Proc Natl Acad Sci U S A 2005
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POT1 as a terminal transducer of TRF1 telomere length control.
Diego Loayza, Titia De Lange. Nature 2003
Diego Loayza, Titia De Lange. Nature 2003
10
CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle.
Grzegorz Sarek, Panagiotis Kotsantis, Phil Ruis, David Van Ly, Pol Margalef, Valerie Borel, Xiao-Feng Zheng, Helen R Flynn, Ambrosius P Snijders, Dipanjan Chowdhury,[...]. Nature 2019
Grzegorz Sarek, Panagiotis Kotsantis, Phil Ruis, David Van Ly, Pol Margalef, Valerie Borel, Xiao-Feng Zheng, Helen R Flynn, Ambrosius P Snijders, Dipanjan Chowdhury,[...]. Nature 2019
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Causes and consequences of replication stress.
Michelle K Zeman, Karlene A Cimprich. Nat Cell Biol 2014
Michelle K Zeman, Karlene A Cimprich. Nat Cell Biol 2014
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FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops.
Bruno Silva, Richard Pentz, Ana Margarida Figueira, Rajika Arora, Yong Woo Lee, Charlotte Hodson, Harry Wischnewski, Andrew J Deans, Claus M Azzalin. Nat Commun 2019
Bruno Silva, Richard Pentz, Ana Margarida Figueira, Rajika Arora, Yong Woo Lee, Charlotte Hodson, Harry Wischnewski, Andrew J Deans, Claus M Azzalin. Nat Commun 2019
23
The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT).
Robert Lu, Julienne J O'Rourke, Alexander P Sobinoff, Joshua A M Allen, Christopher B Nelson, Christopher G Tomlinson, Michael Lee, Roger R Reddel, Andrew J Deans, Hilda A Pickett. Nat Commun 2019
Robert Lu, Julienne J O'Rourke, Alexander P Sobinoff, Joshua A M Allen, Christopher B Nelson, Christopher G Tomlinson, Michael Lee, Roger R Reddel, Andrew J Deans, Hilda A Pickett. Nat Commun 2019
22
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.