David I Brown, Kathy K Griendling. Free Radic Biol Med 2009
Times Cited: 589
Times Cited: 589
Times Cited
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The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology.
Karen Bedard, Karl-Heinz Krause. Physiol Rev 2007
Karen Bedard, Karl-Heinz Krause. Physiol Rev 2007
32
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NADPH oxidases: an overview from structure to innate immunity-associated pathologies.
Arvind Panday, Malaya K Sahoo, Diana Osorio, Sanjay Batra. Cell Mol Immunol 2015
Arvind Panday, Malaya K Sahoo, Diana Osorio, Sanjay Batra. Cell Mol Immunol 2015
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Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5.
G Cheng, Z Cao, X Xu, E G van Meir, J D Lambeth. Gene 2001
G Cheng, Z Cao, X Xu, E G van Meir, J D Lambeth. Gene 2001
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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement.
Sebastian Altenhöfer, Kim A Radermacher, Pamela W M Kleikers, Kirstin Wingler, Harald H H W Schmidt. Antioxid Redox Signal 2015
Sebastian Altenhöfer, Kim A Radermacher, Pamela W M Kleikers, Kirstin Wingler, Harald H H W Schmidt. Antioxid Redox Signal 2015
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NOX Activation by Subunit Interaction and Underlying Mechanisms in Disease.
Radhika Rastogi, Xiaokun Geng, Fengwu Li, Yuchuan Ding. Front Cell Neurosci 2017
Radhika Rastogi, Xiaokun Geng, Fengwu Li, Yuchuan Ding. Front Cell Neurosci 2017
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Crosstalk of reactive oxygen species and NF-κB signaling.
Michael J Morgan, Zheng-gang Liu. Cell Res 2011
Michael J Morgan, Zheng-gang Liu. Cell Res 2011
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ROS function in redox signaling and oxidative stress.
Michael Schieber, Navdeep S Chandel. Curr Biol 2014
Michael Schieber, Navdeep S Chandel. Curr Biol 2014
7
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes.
B Bánfi, G Molnár, A Maturana, K Steger, B Hegedûs, N Demaurex, K H Krause. J Biol Chem 2001
B Bánfi, G Molnár, A Maturana, K Steger, B Hegedûs, N Demaurex, K H Krause. J Biol Chem 2001
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Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases.
Kendra D Martyn, Linda M Frederick, Katharina von Loehneysen, Mary C Dinauer, Ulla G Knaus. Cell Signal 2006
Kendra D Martyn, Linda M Frederick, Katharina von Loehneysen, Mary C Dinauer, Ulla G Knaus. Cell Signal 2006
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Nox family NADPH oxidases: Molecular mechanisms of activation.
Ralf P Brandes, Norbert Weissmann, Katrin Schröder. Free Radic Biol Med 2014
Ralf P Brandes, Norbert Weissmann, Katrin Schröder. Free Radic Biol Med 2014
6
The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4.
Ina Takac, Katrin Schröder, Leilei Zhang, Bernard Lardy, Narayana Anilkumar, J David Lambeth, Ajay M Shah, Francoise Morel, Ralf P Brandes. J Biol Chem 2011
Ina Takac, Katrin Schröder, Leilei Zhang, Bernard Lardy, Narayana Anilkumar, J David Lambeth, Ajay M Shah, Francoise Morel, Ralf P Brandes. J Biol Chem 2011
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Physiological roles of mitochondrial reactive oxygen species.
Laura A Sena, Navdeep S Chandel. Mol Cell 2012
Laura A Sena, Navdeep S Chandel. Mol Cell 2012
6
Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release.
Dmitry B Zorov, Magdalena Juhaszova, Steven J Sollott. Physiol Rev 2014
Dmitry B Zorov, Magdalena Juhaszova, Steven J Sollott. Physiol Rev 2014
6
5
Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases.
Takehiko Ueyama, Miklós Geiszt, Thomas L Leto. Mol Cell Biol 2006
Takehiko Ueyama, Miklós Geiszt, Thomas L Leto. Mol Cell Biol 2006
5
Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase.
Rainer Paffenholz, Rebecca A Bergstrom, Francesca Pasutto, Philipp Wabnitz, Robert J Munroe, Wolfgang Jagla, Ulrich Heinzmann, Andreas Marquardt, Armin Bareiss, Jürgen Laufs,[...]. Genes Dev 2004
Rainer Paffenholz, Rebecca A Bergstrom, Francesca Pasutto, Philipp Wabnitz, Robert J Munroe, Wolfgang Jagla, Ulrich Heinzmann, Andreas Marquardt, Armin Bareiss, Jürgen Laufs,[...]. Genes Dev 2004
5
Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5).
Botond Bánfi, Fabiana Tirone, Isabelle Durussel, Judit Knisz, Patryk Moskwa, Gergely Zoltán Molnár, Karl-Heinz Krause, Jos A Cox. J Biol Chem 2004
Botond Bánfi, Fabiana Tirone, Isabelle Durussel, Judit Knisz, Patryk Moskwa, Gergely Zoltán Molnár, Karl-Heinz Krause, Jos A Cox. J Biol Chem 2004
5
Identification of renox, an NAD(P)H oxidase in kidney.
M Geiszt, J B Kopp, P Várnai, T L Leto. Proc Natl Acad Sci U S A 2000
M Geiszt, J B Kopp, P Várnai, T L Leto. Proc Natl Acad Sci U S A 2000
5
NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts.
Ioan Cucoranu, Roza Clempus, Anna Dikalova, Patrick J Phelan, Srividya Ariyan, Sergey Dikalov, Dan Sorescu. Circ Res 2005
Ioan Cucoranu, Roza Clempus, Anna Dikalova, Patrick J Phelan, Srividya Ariyan, Sergey Dikalov, Dan Sorescu. Circ Res 2005
5
p47phox, the phagocyte NADPH oxidase/NOX2 organizer: structure, phosphorylation and implication in diseases.
Jame El-Benna, Pham My-Chan Dang, Marie Anne Gougerot-Pocidalo, Jean Claude Marie, Francoise Braut-Boucher. Exp Mol Med 2009
Jame El-Benna, Pham My-Chan Dang, Marie Anne Gougerot-Pocidalo, Jean Claude Marie, Francoise Braut-Boucher. Exp Mol Med 2009
5
NADPH oxidases in vascular pathology.
Anna Konior, Agata Schramm, Marta Czesnikiewicz-Guzik, Tomasz J Guzik. Antioxid Redox Signal 2014
Anna Konior, Agata Schramm, Marta Czesnikiewicz-Guzik, Tomasz J Guzik. Antioxid Redox Signal 2014
5
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling.
Paul D Ray, Bo-Wen Huang, Yoshiaki Tsuji. Cell Signal 2012
Paul D Ray, Bo-Wen Huang, Yoshiaki Tsuji. Cell Signal 2012
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Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor.
Kazufumi Hirano, Woei Shin Chen, Adeline L W Chueng, Angela A Dunne, Tamara Seredenina, Aleksandra Filippova, Sumitra Ramachandran, Angela Bridges, Laiq Chaudry, Gary Pettman,[...]. Antioxid Redox Signal 2015
Kazufumi Hirano, Woei Shin Chen, Adeline L W Chueng, Angela A Dunne, Tamara Seredenina, Aleksandra Filippova, Sumitra Ramachandran, Angela Bridges, Laiq Chaudry, Gary Pettman,[...]. Antioxid Redox Signal 2015
6
NADPH oxidases: functions and pathologies in the vasculature.
Bernard Lassègue, Kathy K Griendling. Arterioscler Thromb Vasc Biol 2010
Bernard Lassègue, Kathy K Griendling. Arterioscler Thromb Vasc Biol 2010
5
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.
K J Livak, T D Schmittgen. Methods 2001
K J Livak, T D Schmittgen. Methods 2001
5
NADPH oxidase in brain injury and neurodegenerative disorders.
Merry W Ma, Jing Wang, Quanguang Zhang, Ruimin Wang, Krishnan M Dhandapani, Ratna K Vadlamudi, Darrell W Brann. Mol Neurodegener 2017
Merry W Ma, Jing Wang, Quanguang Zhang, Ruimin Wang, Krishnan M Dhandapani, Ratna K Vadlamudi, Darrell W Brann. Mol Neurodegener 2017
5
Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.
F E Rey, M E Cifuentes, A Kiarash, M T Quinn, P J Pagano. Circ Res 2001
F E Rey, M E Cifuentes, A Kiarash, M T Quinn, P J Pagano. Circ Res 2001
5
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents.
Helmut Sies, Dean P Jones. Nat Rev Mol Cell Biol 2020
Helmut Sies, Dean P Jones. Nat Rev Mol Cell Biol 2020
5
Reactive Oxygen Species in Metabolic and Inflammatory Signaling.
Steven J Forrester, Daniel S Kikuchi, Marina S Hernandes, Qian Xu, Kathy K Griendling. Circ Res 2018
Steven J Forrester, Daniel S Kikuchi, Marina S Hernandes, Qian Xu, Kathy K Griendling. Circ Res 2018
5
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.
Lena Serrander, Laetitia Cartier, Karen Bedard, Botond Banfi, Bernard Lardy, Olivier Plastre, Andrzej Sienkiewicz, Lászlo Fórró, Werner Schlegel, Karl-Heinz Krause. Biochem J 2007
Lena Serrander, Laetitia Cartier, Karen Bedard, Botond Banfi, Bernard Lardy, Olivier Plastre, Andrzej Sienkiewicz, Lászlo Fórró, Werner Schlegel, Karl-Heinz Krause. Biochem J 2007
5
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes.
Tetsuro Ago, Junya Kuroda, Jayashree Pain, Cexiong Fu, Hong Li, Junichi Sadoshima. Circ Res 2010
Tetsuro Ago, Junya Kuroda, Jayashree Pain, Cexiong Fu, Hong Li, Junichi Sadoshima. Circ Res 2010
4
Regulation of Nox enzymes expression in vascular pathophysiology: Focusing on transcription factors and epigenetic mechanisms.
Simona-Adriana Manea, Alina Constantin, Gina Manda, Shlomo Sasson, Adrian Manea. Redox Biol 2015
Simona-Adriana Manea, Alina Constantin, Gina Manda, Shlomo Sasson, Adrian Manea. Redox Biol 2015
5
NOX5: from basic biology to signaling and disease.
Karen Bedard, Vincent Jaquet, Karl-Heinz Krause. Free Radic Biol Med 2012
Karen Bedard, Vincent Jaquet, Karl-Heinz Krause. Free Radic Biol Med 2012
4
Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production.
Sergey I Dikalov, Anna E Dikalova, Alfiya T Bikineyeva, Harald H H W Schmidt, David G Harrison, Kathy K Griendling. Free Radic Biol Med 2008
Sergey I Dikalov, Anna E Dikalova, Alfiya T Bikineyeva, Harald H H W Schmidt, David G Harrison, Kathy K Griendling. Free Radic Biol Med 2008
4
Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system.
Bernard Lassègue, Alejandra San Martín, Kathy K Griendling. Circ Res 2012
Bernard Lassègue, Alejandra San Martín, Kathy K Griendling. Circ Res 2012
4
Crystal structures and atomic model of NADPH oxidase.
Francesca Magnani, Simone Nenci, Elisa Millana Fananas, Marta Ceccon, Elvira Romero, Marco W Fraaije, Andrea Mattevi. Proc Natl Acad Sci U S A 2017
Francesca Magnani, Simone Nenci, Elisa Millana Fananas, Marta Ceccon, Elvira Romero, Marco W Fraaije, Andrea Mattevi. Proc Natl Acad Sci U S A 2017
7
Cell transformation by the superoxide-generating oxidase Mox1.
Y A Suh, R S Arnold, B Lassegue, J Shi, X Xu, D Sorescu, A B Chung, K K Griendling, J D Lambeth. Nature 1999
Y A Suh, R S Arnold, B Lassegue, J Shi, X Xu, D Sorescu, A B Chung, K K Griendling, J D Lambeth. Nature 1999
4
Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase.
Rashmi K Ambasta, Pravir Kumar, Kathy K Griendling, Harald H H W Schmidt, Rudi Busse, Ralf P Brandes. J Biol Chem 2004
Rashmi K Ambasta, Pravir Kumar, Kathy K Griendling, Harald H H W Schmidt, Rudi Busse, Ralf P Brandes. J Biol Chem 2004
4
Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
4
Molecular basis of phosphorylation-induced activation of the NADPH oxidase.
Yvonne Groemping, Karine Lapouge, Stephen J Smerdon, Katrin Rittinger. Cell 2003
Yvonne Groemping, Karine Lapouge, Stephen J Smerdon, Katrin Rittinger. Cell 2003
4
Molecular composition and regulation of the Nox family NAD(P)H oxidases.
Hideki Sumimoto, Kei Miyano, Ryu Takeya. Biochem Biophys Res Commun 2005
Hideki Sumimoto, Kei Miyano, Ryu Takeya. Biochem Biophys Res Commun 2005
4
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.
Louise Hecker, Ragini Vittal, Tamara Jones, Rajesh Jagirdar, Tracy R Luckhardt, Jeffrey C Horowitz, Subramaniam Pennathur, Fernando J Martinez, Victor J Thannickal. Nat Med 2009
Louise Hecker, Ragini Vittal, Tamara Jones, Rajesh Jagirdar, Tracy R Luckhardt, Jeffrey C Horowitz, Subramaniam Pennathur, Fernando J Martinez, Victor J Thannickal. Nat Med 2009
4
ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis.
Benoît D'Autréaux, Michel B Toledano. Nat Rev Mol Cell Biol 2007
Benoît D'Autréaux, Michel B Toledano. Nat Rev Mol Cell Biol 2007
4
Therapeutic potential of NADPH oxidase 1/4 inhibitors.
G Teixeira, C Szyndralewiez, S Molango, S Carnesecchi, F Heitz, P Wiesel, J M Wood. Br J Pharmacol 2017
G Teixeira, C Szyndralewiez, S Molango, S Carnesecchi, F Heitz, P Wiesel, J M Wood. Br J Pharmacol 2017
4
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis.
Goran Bjelakovic, Dimitrinka Nikolova, Lise Lotte Gluud, Rosa G Simonetti, Christian Gluud. JAMA 2007
Goran Bjelakovic, Dimitrinka Nikolova, Lise Lotte Gluud, Rosa G Simonetti, Christian Gluud. JAMA 2007
4
Aiding and abetting roles of NOX oxidases in cellular transformation.
Karen Block, Yves Gorin. Nat Rev Cancer 2012
Karen Block, Yves Gorin. Nat Rev Cancer 2012
4
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