Seija Lehnardt. Glia 2010
Times Cited: 412
Times Cited: 412
Times Cited
Times Co-cited
Similarity
Neurotoxic reactive astrocytes are induced by activated microglia.
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
17
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo.
Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen. Science 2005
Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen. Science 2005
16
Physiology of microglia.
Helmut Kettenmann, Uwe-Karsten Hanisch, Mami Noda, Alexei Verkhratsky. Physiol Rev 2011
Helmut Kettenmann, Uwe-Karsten Hanisch, Mami Noda, Alexei Verkhratsky. Physiol Rev 2011
15
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms.
Michelle L Block, Luigi Zecca, Jau-Shyong Hong. Nat Rev Neurosci 2007
Michelle L Block, Luigi Zecca, Jau-Shyong Hong. Nat Rev Neurosci 2007
14
ATP mediates rapid microglial response to local brain injury in vivo.
Dimitrios Davalos, Jaime Grutzendler, Guang Yang, Jiyun V Kim, Yi Zuo, Steffen Jung, Dan R Littman, Michael L Dustin, Wen-Biao Gan. Nat Neurosci 2005
Dimitrios Davalos, Jaime Grutzendler, Guang Yang, Jiyun V Kim, Yi Zuo, Steffen Jung, Dan R Littman, Michael L Dustin, Wen-Biao Gan. Nat Neurosci 2005
12
Fate mapping analysis reveals that adult microglia derive from primitive macrophages.
Florent Ginhoux, Melanie Greter, Marylene Leboeuf, Sayan Nandi, Peter See, Solen Gokhan, Mark F Mehler, Simon J Conway, Lai Guan Ng, E Richard Stanley,[...]. Science 2010
Florent Ginhoux, Melanie Greter, Marylene Leboeuf, Sayan Nandi, Peter See, Solen Gokhan, Mark F Mehler, Simon J Conway, Lai Guan Ng, E Richard Stanley,[...]. Science 2010
12
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs.
Julie K Olson, Stephen D Miller. J Immunol 2004
Julie K Olson, Stephen D Miller. J Immunol 2004
11
Alternatively activated microglia and macrophages in the central nervous system.
Rafael Franco, Diana Fernández-Suárez. Prog Neurobiol 2015
Rafael Franco, Diana Fernández-Suárez. Prog Neurobiol 2015
10
Microglia in Physiology and Disease.
Susanne A Wolf, H W G M Boddeke, Helmut Kettenmann. Annu Rev Physiol 2017
Susanne A Wolf, H W G M Boddeke, Helmut Kettenmann. Annu Rev Physiol 2017
10
Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential.
Mark L Hanke, Tammy Kielian. Clin Sci (Lond) 2011
Mark L Hanke, Tammy Kielian. Clin Sci (Lond) 2011
9
Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway.
Seija Lehnardt, Leon Massillon, Pamela Follett, Frances E Jensen, Rajiv Ratan, Paul A Rosenberg, Joseph J Volpe, Timothy Vartanian. Proc Natl Acad Sci U S A 2003
Seija Lehnardt, Leon Massillon, Pamela Follett, Frances E Jensen, Rajiv Ratan, Paul A Rosenberg, Joseph J Volpe, Timothy Vartanian. Proc Natl Acad Sci U S A 2003
9
Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases.
Yu Tang, Weidong Le. Mol Neurobiol 2016
Yu Tang, Weidong Le. Mol Neurobiol 2016
9
New tools for studying microglia in the mouse and human CNS.
Mariko L Bennett, F Chris Bennett, Shane A Liddelow, Bahareh Ajami, Jennifer L Zamanian, Nathaniel B Fernhoff, Sara B Mulinyawe, Christopher J Bohlen, Aykezar Adil, Andrew Tucker,[...]. Proc Natl Acad Sci U S A 2016
Mariko L Bennett, F Chris Bennett, Shane A Liddelow, Bahareh Ajami, Jennifer L Zamanian, Nathaniel B Fernhoff, Sara B Mulinyawe, Christopher J Bohlen, Aykezar Adil, Andrew Tucker,[...]. Proc Natl Acad Sci U S A 2016
9
Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor.
Christopher N Parkhurst, Guang Yang, Ipe Ninan, Jeffrey N Savas, John R Yates, Juan J Lafaille, Barbara L Hempstead, Dan R Littman, Wen-Biao Gan. Cell 2013
Christopher N Parkhurst, Guang Yang, Ipe Ninan, Jeffrey N Savas, John R Yates, Juan J Lafaille, Barbara L Hempstead, Dan R Littman, Wen-Biao Gan. Cell 2013
9
TLR signaling tailors innate immune responses in human microglia and astrocytes.
Carolyn S Jack, Nathalie Arbour, Joshua Manusow, Vivianne Montgrain, Manon Blain, Ellie McCrea, Aaron Shapiro, Jack P Antel. J Immunol 2005
Carolyn S Jack, Nathalie Arbour, Joshua Manusow, Vivianne Montgrain, Manon Blain, Ellie McCrea, Aaron Shapiro, Jack P Antel. J Immunol 2005
8
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.
K J Livak, T D Schmittgen. Methods 2001
K J Livak, T D Schmittgen. Methods 2001
8
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
8
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.
Bahareh Ajami, Jami L Bennett, Charles Krieger, Wolfram Tetzlaff, Fabio M V Rossi. Nat Neurosci 2007
Bahareh Ajami, Jami L Bennett, Charles Krieger, Wolfram Tetzlaff, Fabio M V Rossi. Nat Neurosci 2007
8
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors.
Taro Kawai, Shizuo Akira. Nat Immunol 2010
Taro Kawai, Shizuo Akira. Nat Immunol 2010
7
Microglia in neurodegenerative disease.
V Hugh Perry, James A R Nicoll, Clive Holmes. Nat Rev Neurol 2010
V Hugh Perry, James A R Nicoll, Clive Holmes. Nat Rev Neurol 2010
7
Neuroinflammation in Alzheimer's disease.
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
7
Microglial cell origin and phenotypes in health and disease.
Kaoru Saijo, Christopher K Glass. Nat Rev Immunol 2011
Kaoru Saijo, Christopher K Glass. Nat Rev Immunol 2011
7
Mechanisms underlying inflammation in neurodegeneration.
Christopher K Glass, Kaoru Saijo, Beate Winner, Maria Carolina Marchetto, Fred H Gage. Cell 2010
Christopher K Glass, Kaoru Saijo, Beate Winner, Maria Carolina Marchetto, Fred H Gage. Cell 2010
7
Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains.
P L McGeer, S Itagaki, B E Boyes, E G McGeer. Neurology 1988
P L McGeer, S Itagaki, B E Boyes, E G McGeer. Neurology 1988
7
7
The P2Y12 receptor regulates microglial activation by extracellular nucleotides.
Sharon E Haynes, Gunther Hollopeter, Guang Yang, Dana Kurpius, Michael E Dailey, Wen-Biao Gan, David Julius. Nat Neurosci 2006
Sharon E Haynes, Gunther Hollopeter, Guang Yang, Dana Kurpius, Michael E Dailey, Wen-Biao Gan, David Julius. Nat Neurosci 2006
7
Exploring the full spectrum of macrophage activation.
David M Mosser, Justin P Edwards. Nat Rev Immunol 2008
David M Mosser, Justin P Edwards. Nat Rev Immunol 2008
7
Synaptic pruning by microglia is necessary for normal brain development.
Rosa C Paolicelli, Giulia Bolasco, Francesca Pagani, Laura Maggi, Maria Scianni, Patrizia Panzanelli, Maurizio Giustetto, Tiago Alves Ferreira, Eva Guiducci, Laura Dumas,[...]. Science 2011
Rosa C Paolicelli, Giulia Bolasco, Francesca Pagani, Laura Maggi, Maria Scianni, Patrizia Panzanelli, Maurizio Giustetto, Tiago Alves Ferreira, Eva Guiducci, Laura Dumas,[...]. Science 2011
7
Microglial brain region-dependent diversity and selective regional sensitivities to aging.
Kathleen Grabert, Tom Michoel, Michail H Karavolos, Sara Clohisey, J Kenneth Baillie, Mark P Stevens, Tom C Freeman, Kim M Summers, Barry W McColl. Nat Neurosci 2016
Kathleen Grabert, Tom Michoel, Michail H Karavolos, Sara Clohisey, J Kenneth Baillie, Mark P Stevens, Tom C Freeman, Kim M Summers, Barry W McColl. Nat Neurosci 2016
7
Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain.
Monica R P Elmore, Allison R Najafi, Maya A Koike, Nabil N Dagher, Elizabeth E Spangenberg, Rachel A Rice, Masashi Kitazawa, Bernice Matusow, Hoa Nguyen, Brian L West,[...]. Neuron 2014
Monica R P Elmore, Allison R Najafi, Maya A Koike, Nabil N Dagher, Elizabeth E Spangenberg, Rachel A Rice, Masashi Kitazawa, Bernice Matusow, Hoa Nguyen, Brian L West,[...]. Neuron 2014
7
Microglia: active sensor and versatile effector cells in the normal and pathologic brain.
Uwe-Karsten Hanisch, Helmut Kettenmann. Nat Neurosci 2007
Uwe-Karsten Hanisch, Helmut Kettenmann. Nat Neurosci 2007
7
Review: activation patterns of microglia and their identification in the human brain.
D Boche, V H Perry, J A R Nicoll. Neuropathol Appl Neurobiol 2013
D Boche, V H Perry, J A R Nicoll. Neuropathol Appl Neurobiol 2013
7
Neuroinflammation and M2 microglia: the good, the bad, and the inflamed.
Jonathan D Cherry, John A Olschowka, M Kerry O'Banion. J Neuroinflammation 2014
Jonathan D Cherry, John A Olschowka, M Kerry O'Banion. J Neuroinflammation 2014
7
The impact of single and pairwise Toll-like receptor activation on neuroinflammation and neurodegeneration.
Karen Rosenberger, Katja Derkow, Paul Dembny, Christina Krüger, Eckart Schott, Seija Lehnardt. J Neuroinflammation 2014
Karen Rosenberger, Katja Derkow, Paul Dembny, Christina Krüger, Eckart Schott, Seija Lehnardt. J Neuroinflammation 2014
11
7
TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.
Yaming Wang, Marina Cella, Kaitlin Mallinson, Jason D Ulrich, Katherine L Young, Michelle L Robinette, Susan Gilfillan, Gokul M Krishnan, Shwetha Sudhakar, Bernd H Zinselmeyer,[...]. Cell 2015
Yaming Wang, Marina Cella, Kaitlin Mallinson, Jason D Ulrich, Katherine L Young, Michelle L Robinette, Susan Gilfillan, Gokul M Krishnan, Shwetha Sudhakar, Bernd H Zinselmeyer,[...]. Cell 2015
6
Innate immune activation in neurodegenerative disease.
Michael T Heneka, Markus P Kummer, Eicke Latz. Nat Rev Immunol 2014
Michael T Heneka, Markus P Kummer, Eicke Latz. Nat Rev Immunol 2014
6
Neuroinflammation in Parkinson's disease: a target for neuroprotection?
Etienne C Hirsch, Stéphane Hunot. Lancet Neurol 2009
Etienne C Hirsch, Stéphane Hunot. Lancet Neurol 2009
6
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.
L Alexopoulou, A C Holt, R Medzhitov, R A Flavell. Nature 2001
L Alexopoulou, A C Holt, R Medzhitov, R A Flavell. Nature 2001
6
Broad expression of Toll-like receptors in the human central nervous system.
Malika Bsibsi, Rivka Ravid, Djordje Gveric, Johannes M van Noort. J Neuropathol Exp Neurol 2002
Malika Bsibsi, Rivka Ravid, Djordje Gveric, Johannes M van Noort. J Neuropathol Exp Neurol 2002
6
Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution.
Takahiro Masuda, Roman Sankowski, Ori Staszewski, Chotima Böttcher, Lukas Amann, Sagar, Christian Scheiwe, Stefan Nessler, Patrik Kunz, Geert van Loo,[...]. Nature 2019
Takahiro Masuda, Roman Sankowski, Ori Staszewski, Chotima Böttcher, Lukas Amann, Sagar, Christian Scheiwe, Stefan Nessler, Patrik Kunz, Geert van Loo,[...]. Nature 2019
6
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain.
L J Lawson, V H Perry, P Dri, S Gordon. Neuroscience 1990
L J Lawson, V H Perry, P Dri, S Gordon. Neuroscience 1990
6
Microglial M1/M2 polarization and metabolic states.
Ruben Orihuela, Christopher A McPherson, Gaylia Jean Harry. Br J Pharmacol 2016
Ruben Orihuela, Christopher A McPherson, Gaylia Jean Harry. Br J Pharmacol 2016
6
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Sabrina M Lehmann, Christina Krüger, Boyoun Park, Katja Derkow, Karen Rosenberger, Jan Baumgart, Thorsten Trimbuch, Gina Eom, Michael Hinz, David Kaul,[...]. Nat Neurosci 2012
Sabrina M Lehmann, Christina Krüger, Boyoun Park, Katja Derkow, Karen Rosenberger, Jan Baumgart, Thorsten Trimbuch, Gina Eom, Michael Hinz, David Kaul,[...]. Nat Neurosci 2012
6
Reactive Astrocytes: Production, Function, and Therapeutic Potential.
Shane A Liddelow, Ben A Barres. Immunity 2017
Shane A Liddelow, Ben A Barres. Immunity 2017
6
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.
Timothy R Hammond, Connor Dufort, Lasse Dissing-Olesen, Stefanie Giera, Adam Young, Alec Wysoker, Alec J Walker, Frederick Gergits, Michael Segel, James Nemesh,[...]. Immunity 2019
Timothy R Hammond, Connor Dufort, Lasse Dissing-Olesen, Stefanie Giera, Adam Young, Alec Wysoker, Alec J Walker, Frederick Gergits, Michael Segel, James Nemesh,[...]. Immunity 2019
6
Role of Microglia TLRs in Neurodegeneration.
Bernd L Fiebich, Carla Ribeiro Alvares Batista, Soraya Wilke Saliba, Nizar M Yousif, Antonio Carlos Pinheiro de Oliveira. Front Cell Neurosci 2018
Bernd L Fiebich, Carla Ribeiro Alvares Batista, Soraya Wilke Saliba, Nizar M Yousif, Antonio Carlos Pinheiro de Oliveira. Front Cell Neurosci 2018
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.