A citation-based method for searching scientific literature

Denis Drygin, Adam Siddiqui-Jain, Sean O'Brien, Michael Schwaebe, Amy Lin, Josh Bliesath, Caroline B Ho, Chris Proffitt, Katy Trent, Jeffrey P Whitten, John K C Lim, Daniel Von Hoff, Kenna Anderes, William G Rice. Cancer Res 2009
Times Cited: 366







List of co-cited articles
1393 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.
Hong Xu, Marco Di Antonio, Steven McKinney, Veena Mathew, Brandon Ho, Nigel J O'Neil, Nancy Dos Santos, Jennifer Silvester, Vivien Wei, Jessica Garcia,[...]. Nat Commun 2017
265
49

High-throughput sequencing of DNA G-quadruplex structures in the human genome.
Vicki S Chambers, Giovanni Marsico, Jonathan M Boutell, Marco Di Antonio, Geoffrey P Smith, Shankar Balasubramanian. Nat Biotechnol 2015
625
29

Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.
Denis Drygin, Amy Lin, Josh Bliesath, Caroline B Ho, Sean E O'Brien, Chris Proffitt, Mayuko Omori, Mustapha Haddach, Michael K Schwaebe, Adam Siddiqui-Jain,[...]. Cancer Res 2011
363
28

Quantitative visualization of DNA G-quadruplex structures in human cells.
Giulia Biffi, David Tannahill, John McCafferty, Shankar Balasubramanian. Nat Chem 2013
27

G-quadruplex structures mark human regulatory chromatin.
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
419
27

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Shankar Balasubramanian, Laurence H Hurley, Stephen Neidle. Nat Rev Drug Discov 2011
25

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.
Adam Siddiqui-Jain, Cory L Grand, David J Bearss, Laurence H Hurley. Proc Natl Acad Sci U S A 2002
24

Quadruplex DNA: sequence, topology and structure.
Sarah Burge, Gary N Parkinson, Pascale Hazel, Alan K Todd, Stephen Neidle. Nucleic Acids Res 2006
22

Prevalence of quadruplexes in the human genome.
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2005
22

Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Megan J Bywater, Gretchen Poortinga, Elaine Sanij, Nadine Hein, Abigail Peck, Carleen Cullinane, Meaghan Wall, Leonie Cluse, Denis Drygin, Kenna Anderes,[...]. Cancer Cell 2012
384
22

The Structure and Function of DNA G-Quadruplexes.
Jochen Spiegel, Santosh Adhikari, Shankar Balasubramanian. Trends Chem 2020
246
20

DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential.
Robert Hänsel-Hertsch, Marco Di Antonio, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2017
442
19

G-quadruplexes and their regulatory roles in biology.
Daniela Rhodes, Hans J Lipps. Nucleic Acids Res 2015
811
18

The regulation and functions of DNA and RNA G-quadruplexes.
Dhaval Varshney, Jochen Spiegel, Katherine Zyner, David Tannahill, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2020
308
17

Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy.
Sefan Asamitsu, Shunsuke Obata, Zutao Yu, Toshikazu Bando, Hiroshi Sugiyama. Molecules 2019
147
16

Inhibition of human telomerase by a G-quadruplex-interactive compound.
D Sun, B Thompson, B E Cathers, M Salazar, S M Kerwin, J O Trent, T C Jenkins, S Neidle, L H Hurley. J Med Chem 1997
607
15

Helix formation by guanylic acid.
M GELLERT, M N LIPSETT, D R DAVIES. Proc Natl Acad Sci U S A 1962
15

G-quadruplexes in promoters throughout the human genome.
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2007
873
15

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study.
Amit Khot, Natalie Brajanovski, Donald P Cameron, Nadine Hein, Kylee H Maclachlan, Elaine Sanij, John Lim, John Soong, Emma Link, Piers Blombery,[...]. Cancer Discov 2019
80
18

Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian, Stephen P Jackson. Nat Chem Biol 2012
432
14

G-quadruplexes and helicases.
Oscar Mendoza, Anne Bourdoncle, Jean-Baptiste Boulé, Robert M Brosh, Jean-Louis Mergny. Nucleic Acids Res 2016
253
14

DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells.
Alessio De Magis, Stefano G Manzo, Marco Russo, Jessica Marinello, Rita Morigi, Olivier Sordet, Giovanni Capranico. Proc Natl Acad Sci U S A 2019
131
13


Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.
Jutta Zimmer, Eliana M C Tacconi, Cecilia Folio, Sophie Badie, Manuela Porru, Kerstin Klare, Manuela Tumiati, Enni Markkanen, Swagata Halder, Anderson Ryan,[...]. Mol Cell 2016
133
13


DNA secondary structures: stability and function of G-quadruplex structures.
Matthew L Bochman, Katrin Paeschke, Virginia A Zakian. Nat Rev Genet 2012
825
13

The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning.
Peter M Bruno, Mengrou Lu, Kady A Dennis, Haider Inam, Connor J Moore, John Sheehe, Stephen J Elledge, Michael T Hemann, Justin R Pritchard. Proc Natl Acad Sci U S A 2020
56
23

G-quadruplex, Friend or Foe: The Role of the G-quartet in Anticancer Strategies.
Josué Carvalho, Jean-Louis Mergny, Gilmar F Salgado, João A Queiroz, Carla Cruz. Trends Mol Med 2020
99
13

The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.
Angelika M Burger, Fangping Dai, Christoph M Schultes, Anthony P Reszka, Michael J Moore, John A Double, Stephen Neidle. Cancer Res 2005
393
12


Pif1 family helicases suppress genome instability at G-quadruplex motifs.
Katrin Paeschke, Matthew L Bochman, P Daniela Garcia, Petr Cejka, Katherine L Friedman, Stephen C Kowalczykowski, Virginia A Zakian. Nature 2013
315
12

Ribosome biogenesis in cancer: new players and therapeutic avenues.
Joffrey Pelletier, George Thomas, Siniša Volarević. Nat Rev Cancer 2018
309
12

Whole genome experimental maps of DNA G-quadruplexes in multiple species.
Giovanni Marsico, Vicki S Chambers, Aleksandr B Sahakyan, Patrick McCauley, Jonathan M Boutell, Marco Di Antonio, Shankar Balasubramanian. Nucleic Acids Res 2019
150
12

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy.
Emanuela Ruggiero, Sara N Richter. Nucleic Acids Res 2018
203
11

Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells.
Giulia Biffi, Marco Di Antonio, David Tannahill, Shankar Balasubramanian. Nat Chem 2014
372
11

Highly prevalent putative quadruplex sequence motifs in human DNA.
Alan K Todd, Matthew Johnston, Stephen Neidle. Nucleic Acids Res 2005
703
11

Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex.
Mu-Yong Kim, Hariprasad Vankayalapati, Kazuo Shin-Ya, Konstanty Wierzba, Laurence H Hurley. J Am Chem Soc 2002
380
11

Chemotherapeutic drugs inhibit ribosome biogenesis at various levels.
Kaspar Burger, Bastian Mühl, Thomas Harasim, Michaela Rohrmoser, Anastassia Malamoussi, Mathias Orban, Markus Kellner, Anita Gruber-Eber, Elisabeth Kremmer, Michael Hölzel,[...]. J Biol Chem 2010
282
11


Elevated levels of G-quadruplex formation in human stomach and liver cancer tissues.
Giulia Biffi, David Tannahill, Jodi Miller, William J Howat, Shankar Balasubramanian. PLoS One 2014
109
11

Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing.
Robert Hänsel-Hertsch, Jochen Spiegel, Giovanni Marsico, David Tannahill, Shankar Balasubramanian. Nat Protoc 2018
106
11

Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule.
Chiara Marchetti, Katherine G Zyner, Stephan A Ohnmacht, Mathew Robson, Shozeb M Haider, Jennifer P Morton, Giovanni Marsico, Tam Vo, Sarah Laughlin-Toth, Ahmed A Ahmed,[...]. J Med Chem 2018
71
14

Re-evaluation of G-quadruplex propensity with G4Hunter.
Amina Bedrat, Laurent Lacroix, Jean-Louis Mergny. Nucleic Acids Res 2016
313
10

G-quadruplex structures are stable and detectable in human genomic DNA.
Enid Yi Ni Lam, Dario Beraldi, David Tannahill, Shankar Balasubramanian. Nat Commun 2013
299
10

Ligand Design to Acquire Specificity to Intended G-Quadruplex Structures.
Sefan Asamitsu, Toshikazu Bando, Hiroshi Sugiyama. Chemistry 2019
85
11

A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer.
Stephan A Ohnmacht, Chiara Marchetti, Mekala Gunaratnam, Rachael J Besser, Shozeb M Haider, Gloria Di Vita, Helen L Lowe, Maria Mellinas-Gomez, Seckou Diocou, Mathew Robson,[...]. Sci Rep 2015
69
14

Single-molecule visualization of DNA G-quadruplex formation in live cells.
Marco Di Antonio, Aleks Ponjavic, Antanas Radzevičius, Rohan T Ranasinghe, Marco Catalano, Xiaoyun Zhang, Jiazhen Shen, Lisa-Maria Needham, Steven F Lee, David Klenerman,[...]. Nat Chem 2020
108
10

A Small Molecule That Represses Translation of G-Quadruplex-Containing mRNA.
Yousuke Katsuda, Shin-Ichi Sato, Lisa Asano, Yoshitaka Morimura, Tomoyuki Furuta, Hiroshi Sugiyama, Masaki Hagihara, Motonari Uesugi. J Am Chem Soc 2016
46
19

Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus.
K Shin-ya, K Wierzba, K Matsuo, T Ohtani, Y Yamada, K Furihata, Y Hayakawa, H Seto. J Am Chem Soc 2001
364
9

Inhibition of telomerase by G-quartet DNA structures.
A M Zahler, J R Williamson, T R Cech, D M Prescott. Nature 1991
895
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.