A citation-based method for searching scientific literature

Nora Göckler, Guillermo Jofre, Chrisovalantis Papadopoulos, Ulf Soppa, Francisco J Tejedor, Walter Becker. FEBS J 2009
Times Cited: 166







List of co-cited articles
805 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A.
Yasushi Ogawa, Yosuke Nonaka, Toshiyasu Goto, Eriko Ohnishi, Toshiyuki Hiramatsu, Isao Kii, Miyo Yoshida, Teikichi Ikura, Hiroshi Onogi, Hiroshi Shibuya,[...]. Nat Commun 2010
178
41

The selectivity of protein kinase inhibitors: a further update.
Jenny Bain, Lorna Plater, Matt Elliott, Natalia Shpiro, C James Hastie, Hilary McLauchlan, Iva Klevernic, J Simon C Arthur, Dario R Alessi, Philip Cohen. Biochem J 2007
30

The role of DYRK1A in neurodegenerative diseases.
Jerzy Wegiel, Cheng-Xin Gong, Yu-Wen Hwang. FEBS J 2011
166
25

Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.
Tania Tahtouh, Jonathan M Elkins, Panagis Filippakopoulos, Meera Soundararajan, Guillaume Burgy, Emilie Durieu, Claude Cochet, Ralf S Schmid, Donald C Lo, Florent Delhommel,[...]. J Med Chem 2012
138
24

β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites.
Danielle Frost, Bessie Meechoovet, Tong Wang, Stephen Gately, Marco Giorgetti, Irina Shcherbakova, Travis Dunckley. PLoS One 2011
105
24


Activation, regulation, and inhibition of DYRK1A.
Walter Becker, Wolfgang Sippl. FEBS J 2011
140
20


DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications.
Ramzi Abbassi, Terrance G Johns, Michael Kassiou, Lenka Munoz. Pharmacol Ther 2015
96
19

Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors.
Katharina Rüben, Anne Wurzlbauer, Agnes Walte, Wolfgang Sippl, Franz Bracher, Walter Becker. PLoS One 2015
36
52


Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.
Pamela A Lochhead, Gary Sibbet, Nick Morrice, Vaughn Cleghon. Cell 2005
214
17

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.
Meera Soundararajan, Annette K Roos, Pavel Savitsky, Panagis Filippakopoulos, Arminja N Kettenbach, Jesper V Olsen, Scott A Gerber, Jeyanthy Eswaran, Stefan Knapp, Jonathan M Elkins. Structure 2013
97
17

DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.
Larisa Litovchick, Laurence A Florens, Selene K Swanson, Michael P Washburn, James A DeCaprio. Genes Dev 2011
176
17

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome.
Fei Liu, Zhihou Liang, Jerzy Wegiel, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal, Narayan Ramakrishna, Cheng-Xin Gong. FASEB J 2008
160
16

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.
Peng Wang, Juan-Carlos Alvarez-Perez, Dan P Felsenfeld, Hongtao Liu, Sharmila Sivendran, Aaron Bender, Anil Kumar, Roberto Sanchez, Donald K Scott, Adolfo Garcia-Ocaña,[...]. Nat Med 2015
228
16

The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation.
Ulf Soppa, Julian Schumacher, Victoria Florencio Ortiz, Tobias Pasqualon, Francisco J Tejedor, Walter Becker. Cell Cycle 2014
101
15

Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells.
Joongkyu Park, Yohan Oh, Lang Yoo, Min-Su Jung, Woo-Joo Song, Sang-Hun Lee, Hyemyung Seo, Kwang Chul Chung. J Biol Chem 2010
83
18

A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.
Séverine Coutadeur, Hélène Benyamine, Laurence Delalonde, Catherine de Oliveira, Bertrand Leblond, Alicia Foucourt, Thierry Besson, Anne-Sophie Casagrande, Thierry Taverne, Angélique Girard,[...]. J Neurochem 2015
77
19

MNB/DYRK1A as a multiple regulator of neuronal development.
Francisco J Tejedor, Barbara Hämmerle. FEBS J 2011
146
15

Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
Soo-Ryoon Ryoo, Hyun-Jeong Cho, Hye-Won Lee, Hey Kyeong Jeong, Chinzorig Radnaabazar, Yeun-Soo Kim, Min-Jeong Kim, Mi-Young Son, Hyemyung Seo, Sul-Hee Chung,[...]. J Neurochem 2008
137
15

Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth.
Natividad Pozo, Cristina Zahonero, Paloma Fernández, Jose M Liñares, Angel Ayuso, Masatoshi Hagiwara, Angel Pérez, Jose R Ricoy, Aurelio Hernández-Laín, Juan M Sepúlveda,[...]. J Clin Invest 2013
86
16

Inhibition of monoamine oxidase A by beta-carboline derivatives.
H Kim, S O Sablin, R R Ramsay. Arch Biochem Biophys 1997
174
14

10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A.
Hannes Falke, Apirat Chaikuad, Anja Becker, Nadège Loaëc, Olivier Lozach, Samira Abu Jhaisha, Walter Becker, Peter G Jones, Lutz Preu, Knut Baumann,[...]. J Med Chem 2015
57
24

DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.
Soo-Ryoon Ryoo, Hey Kyeong Jeong, Chinzorig Radnaabazar, Jin-Ju Yoo, Hyun-Jeong Cho, Hye-Won Lee, In-Sook Kim, Young-Hee Cheon, Young Soo Ahn, Sul-Hee Chung,[...]. J Biol Chem 2007
171
14

Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice.
Vassiliki Fotaki, Mara Dierssen, Soledad Alcántara, Salvador Martínez, Eulàlia Martí, Caty Casas, Joana Visa, Eduardo Soriano, Xavier Estivill, Maria L Arbonés. Mol Cell Biol 2002
238
13

Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.
S Himpel, P Panzer, K Eirmbter, H Czajkowska, M Sayed, L C Packman, T Blundell, H Kentrup, J Grötzinger, H G Joost,[...]. Biochem J 2001
123
13


Dyrk1A-mediated phosphorylation of Presenilin 1: a functional link between Down syndrome and Alzheimer's disease.
Young Shin Ryu, So Young Park, Min-Su Jung, Song-Hee Yoon, Mi-Yang Kwen, Sun-Young Lee, Sun-Hee Choi, Chinzorig Radnaabazar, Mi-Kyoung Kim, Hangun Kim,[...]. J Neurochem 2010
62
20

The specificities of protein kinase inhibitors: an update.
Jenny Bain, Hilary McLauchlan, Matthew Elliott, Philip Cohen. Biochem J 2003
13


DYRK1A: a potential drug target for multiple Down syndrome neuropathologies.
Walter Becker, Ulf Soppa, Francisco J Tejedor. CNS Neurol Disord Drug Targets 2014
66
19

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.
Joseph R Arron, Monte M Winslow, Alberto Polleri, Ching-Pin Chang, Hai Wu, Xin Gao, Joel R Neilson, Lei Chen, Jeremy J Heit, Seung K Kim,[...]. Nature 2006
498
13

The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.
Ryo Kimura, Kouzin Kamino, Mitsuko Yamamoto, Aidaralieva Nuripa, Tomoyuki Kida, Hiroaki Kazui, Ryota Hashimoto, Toshihisa Tanaka, Takashi Kudo, Hidehisa Yamagata,[...]. Hum Mol Genet 2007
181
13


minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila.
F Tejedor, X R Zhu, E Kaltenbach, A Ackermann, A Baumann, I Canal, M Heisenberg, K F Fischbach, O Pongs. Neuron 1995
299
12



Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling.
Barbara Hämmerle, Edgar Ulin, Jordi Guimera, Walter Becker, François Guillemot, Francisco J Tejedor. Development 2011
84
14

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
Mansour Debdab, François Carreaux, Steven Renault, Meera Soundararajan, Oleg Fedorov, Panagis Filippakopoulos, Olivier Lozach, Lucie Babault, Tania Tahtouh, Blandine Baratte,[...]. J Med Chem 2011
97
12

Function and regulation of Dyrk1A: towards understanding Down syndrome.
Joongkyu Park, Woo-Joo Song, Kwang Chul Chung. Cell Mol Life Sci 2009
136
12


Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation.
Eun Joo Kim, Jee Young Sung, Hyun Jung Lee, Hyewhon Rhim, Masato Hasegawa, Takeshi Iwatsubo, Do Sik Min, Jongsun Kim, Seung R Paik, Kwang Chul Chung. J Biol Chem 2006
83
14

Specificity determinants of substrate recognition by the protein kinase DYRK1A.
S Himpel, W Tegge, R Frank, S Leder, H G Joost, W Becker. J Biol Chem 2000
181
11

Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1.
Junhao Mao, Peter Maye, Priit Kogerman, Francisco J Tejedor, Rune Toftgard, Wei Xie, Guanqing Wu, Dianqing Wu. J Biol Chem 2002
146
11

Development of DANDYs, new 3,5-diaryl-7-azaindoles demonstrating potent DYRK1A kinase inhibitory activity.
Stéphanie Gourdain, Julien Dairou, Clément Denhez, Linh Chi Bui, Fernando Rodrigues-Lima, Nathalie Janel, Jean M Delabar, Kevin Cariou, Robert H Dodd. J Med Chem 2013
38
28

DYRK1A kinase inhibitors with emphasis on cancer.
A Ionescu, F Dufrasne, M Gelbcke, I Jabin, R Kiss, D Lamoral-Theys. Mini Rev Med Chem 2012
51
21

Disruptive de novo mutations of DYRK1A lead to a syndromic form of autism and ID.
B W M van Bon, B P Coe, R Bernier, C Green, J Gerdts, K Witherspoon, T Kleefstra, M H Willemsen, R Kumar, P Bosco,[...]. Mol Psychiatry 2016
96
11

Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.
Ercument Dirice, Deepika Walpita, Amedeo Vetere, Bennett C Meier, Sevim Kahraman, Jiang Hu, Vlado Dančík, Sean M Burns, Tamara J Gilbert, David E Olson,[...]. Diabetes 2016
114
11

Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII.
H Kentrup, W Becker, J Heukelbach, A Wilmes, A Schürmann, C Huppertz, H Kainulainen, H G Joost. J Biol Chem 1996
206
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.