Dawei Jiang, Linlin Zhao, David E Clapham. Science 2009
Times Cited: 366
Times Cited: 366
Times Cited
Times Co-cited
Similarity
NCLX is an essential component of mitochondrial Na+/Ca2+ exchange.
Raz Palty, William F Silverman, Michal Hershfinkel, Teresa Caporale, Stefano L Sensi, Julia Parnis, Christiane Nolte, Daniel Fishman, Varda Shoshan-Barmatz, Sharon Herrmann,[...]. Proc Natl Acad Sci U S A 2010
Raz Palty, William F Silverman, Michal Hershfinkel, Teresa Caporale, Stefano L Sensi, Julia Parnis, Christiane Nolte, Daniel Fishman, Varda Shoshan-Barmatz, Sharon Herrmann,[...]. Proc Natl Acad Sci U S A 2010
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Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.
Joshua M Baughman, Fabiana Perocchi, Hany S Girgis, Molly Plovanich, Casey A Belcher-Timme, Yasemin Sancak, X Robert Bao, Laura Strittmatter, Olga Goldberger, Roman L Bogorad,[...]. Nature 2011
Joshua M Baughman, Fabiana Perocchi, Hany S Girgis, Molly Plovanich, Casey A Belcher-Timme, Yasemin Sancak, X Robert Bao, Laura Strittmatter, Olga Goldberger, Roman L Bogorad,[...]. Nature 2011
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A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.
Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò, Rosario Rizzuto. Nature 2011
Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò, Rosario Rizzuto. Nature 2011
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EMRE is an essential component of the mitochondrial calcium uniporter complex.
Yasemin Sancak, Andrew L Markhard, Toshimori Kitami, Erika Kovács-Bogdán, Kimberli J Kamer, Namrata D Udeshi, Steven A Carr, Dipayan Chaudhuri, David E Clapham, Andrew A Li,[...]. Science 2013
Yasemin Sancak, Andrew L Markhard, Toshimori Kitami, Erika Kovács-Bogdán, Kimberli J Kamer, Namrata D Udeshi, Steven A Carr, Dipayan Chaudhuri, David E Clapham, Andrew A Li,[...]. Science 2013
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The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit.
Anna Raffaello, Diego De Stefani, Davide Sabbadin, Enrico Teardo, Giulia Merli, Anne Picard, Vanessa Checchetto, Stefano Moro, Ildikò Szabò, Rosario Rizzuto. EMBO J 2013
Anna Raffaello, Diego De Stefani, Davide Sabbadin, Enrico Teardo, Giulia Merli, Anne Picard, Vanessa Checchetto, Stefano Moro, Ildikò Szabò, Rosario Rizzuto. EMBO J 2013
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MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake.
Fabiana Perocchi, Vishal M Gohil, Hany S Girgis, X Robert Bao, Janet E McCombs, Amy E Palmer, Vamsi K Mootha. Nature 2010
Fabiana Perocchi, Vishal M Gohil, Hany S Girgis, X Robert Bao, Janet E McCombs, Amy E Palmer, Vamsi K Mootha. Nature 2010
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Functional reconstitution of the mitochondrial Ca2+/H+ antiporter Letm1.
Ming-Feng Tsai, Dawei Jiang, Linlin Zhao, David Clapham, Christopher Miller. J Gen Physiol 2014
Ming-Feng Tsai, Dawei Jiang, Linlin Zhao, David Clapham, Christopher Miller. J Gen Physiol 2014
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MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.
Karthik Mallilankaraman, César Cárdenas, Patrick J Doonan, Harish C Chandramoorthy, Krishna M Irrinki, Tünde Golenár, György Csordás, Priyanka Madireddi, Jun Yang, Marioly Müller,[...]. Nat Cell Biol 2012
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Letm1, the mitochondrial Ca2+/H+ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome.
Dawei Jiang, Linlin Zhao, Clary B Clish, David E Clapham. Proc Natl Acad Sci U S A 2013
Dawei Jiang, Linlin Zhao, Clary B Clish, David E Clapham. Proc Natl Acad Sci U S A 2013
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Mitochondria as sensors and regulators of calcium signalling.
Rosario Rizzuto, Diego De Stefani, Anna Raffaello, Cristina Mammucari. Nat Rev Mol Cell Biol 2012
Rosario Rizzuto, Diego De Stefani, Anna Raffaello, Cristina Mammucari. Nat Rev Mol Cell Biol 2012
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MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity.
Maria Patron, Vanessa Checchetto, Anna Raffaello, Enrico Teardo, Denis Vecellio Reane, Maura Mantoan, Veronica Granatiero, Ildikò Szabò, Diego De Stefani, Rosario Rizzuto. Mol Cell 2014
Maria Patron, Vanessa Checchetto, Anna Raffaello, Enrico Teardo, Denis Vecellio Reane, Maura Mantoan, Veronica Granatiero, Ildikò Szabò, Diego De Stefani, Rosario Rizzuto. Mol Cell 2014
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MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca²⁺ uniporter.
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The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability.
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Leucine zipper-EF-hand containing transmembrane protein 1 (LETM1) forms a Ca2+/H+ antiporter.
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Juan Shao, Zhenglin Fu, Yanli Ji, Xiangchen Guan, Shang Guo, Zhanyu Ding, Xue Yang, Yao Cong, Yuequan Shen. Sci Rep 2016
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The mitochondrial calcium uniporter is a highly selective ion channel.
Yuriy Kirichok, Grigory Krapivinsky, David E Clapham. Nature 2004
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MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling.
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MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.
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The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome.
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LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation.
Patrick J Doonan, Harish C Chandramoorthy, Nicholas E Hoffman, Xueqian Zhang, César Cárdenas, Santhanam Shanmughapriya, Sudarsan Rajan, Sandhya Vallem, Xiongwen Chen, J Kevin Foskett,[...]. FASEB J 2014
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NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD(P)H production and modulating matrix redox state.
Umberto De Marchi, Jaime Santo-Domingo, Cyril Castelbou, Israel Sekler, Andreas Wiederkehr, Nicolas Demaurex. J Biol Chem 2014
Umberto De Marchi, Jaime Santo-Domingo, Cyril Castelbou, Israel Sekler, Andreas Wiederkehr, Nicolas Demaurex. J Biol Chem 2014
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The machineries, regulation and cellular functions of mitochondrial calcium.
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MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.
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Characterization of the mitochondrial protein LETM1, which maintains the mitochondrial tubular shapes and interacts with the AAA-ATPase BCS1L.
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LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux.
Shane Austin, Mojtaba Tavakoli, Christina Pfeiffer, Julia Seifert, Andrea Mattarei, Diego De Stefani, Mario Zoratti, Karin Nowikovsky. Front Physiol 2017
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PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress.
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LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability.
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MICU3 is a tissue-specific enhancer of mitochondrial calcium uptake.
Maria Patron, Veronica Granatiero, Javier Espino, Rosario Rizzuto, Diego De Stefani. Cell Death Differ 2019
Maria Patron, Veronica Granatiero, Javier Espino, Rosario Rizzuto, Diego De Stefani. Cell Death Differ 2019
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The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.
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NCLX: the mitochondrial sodium calcium exchanger.
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Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses.
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LETM1: Essential for Mitochondrial Biology and Cation Homeostasis?
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Trypanosome Letm1 protein is essential for mitochondrial potassium homeostasis.
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Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity.
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Lithium-calcium exchange is mediated by a distinct potassium-independent sodium-calcium exchanger.
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High-affinity cooperative Ca2+ binding by MICU1-MICU2 serves as an on-off switch for the uniporter.
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The versatility and universality of calcium signalling.
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A Drosophila mutant of LETM1, a candidate gene for seizures in Wolf-Hirschhorn syndrome.
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Mitochondrial calcium uptake in organ physiology: from molecular mechanism to animal models.
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Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery.
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Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death.
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X-ray and cryo-EM structures of the mitochondrial calcium uniporter.
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Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels.
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Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.