A citation-based method for searching scientific literature

Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
Times Cited: 563







List of co-cited articles
1349 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
519
29

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.
Loren D Walensky, Andrew L Kung, Iris Escher, Thomas J Malia, Scott Barbuto, Renee D Wright, Gerhard Wagner, Gregory L Verdine, Stanley J Korsmeyer. Science 2004
953
28

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
21

Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide.
Federico Bernal, Andrew F Tyler, Stanley J Korsmeyer, Loren D Walensky, Gregory L Verdine. J Am Chem Soc 2007
362
20

Hydrocarbon-stapled peptides: principles, practice, and progress.
Loren D Walensky, Gregory H Bird. J Med Chem 2014
407
20

Stapled α-helical peptide drug development: a potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy.
Yong S Chang, Bradford Graves, Vincent Guerlavais, Christian Tovar, Kathryn Packman, Kwong-Him To, Karen A Olson, Kamala Kesavan, Pranoti Gangurde, Aditi Mukherjee,[...]. Proc Natl Acad Sci U S A 2013
406
18


Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis.
John Ridgway, Gu Zhang, Yan Wu, Scott Stawicki, Wei-Ching Liang, Yvan Chanthery, Joe Kowalski, Ryan J Watts, Christopher Callahan, Ian Kasman,[...]. Nature 2006
737
14

Notch Signaling in Development, Tissue Homeostasis, and Disease.
Chris Siebel, Urban Lendahl. Physiol Rev 2017
379
14

The Varied Roles of Notch in Cancer.
Jon C Aster, Warren S Pear, Stephen C Blacklow. Annu Rev Pathol 2017
297
13

The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis.
Luisana Astudillo, Thiago G Da Silva, Zhiqiang Wang, Xiaoqing Han, Ke Jin, Jeffrey VanWye, Xiaoxia Zhu, Kelly Weaver, Taiji Oashi, Pedro E M Lopes,[...]. Cancer Res 2016
37
35

A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.
C Papayannidis, D J DeAngelo, W Stock, B Huang, M N Shaik, R Cesari, X Zheng, J M Reynolds, P A English, M Ozeck,[...]. Blood Cancer J 2015
71
18

Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices.
Gregory H Bird, Emanuele Mazzola, Kwadwo Opoku-Nsiah, Margaret A Lammert, Marina Godes, Donna S Neuberg, Loren D Walensky. Nat Chem Biol 2016
114
12

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
665
12

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
Andrew P Weng, John M Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G Rodriguez, Hong Sai, John Tobias,[...]. Genes Dev 2006
629
12

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga,[...]. Nat Med 2009
325
12

Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.
V Agnusdei, S Minuzzo, C Frasson, A Grassi, F Axelrod, S Satyal, A Gurney, T Hoey, E Seganfreddo, G Basso,[...]. Leukemia 2014
83
14

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
B De Strooper, W Annaert, P Cupers, P Saftig, K Craessaerts, J S Mumm, E H Schroeter, V Schrijvers, M S Wolfe, W J Ray,[...]. Nature 1999
11

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
11

Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic.
Gregory H Bird, Navid Madani, Alisa F Perry, Amy M Princiotto, Jeffrey G Supko, Xiaoying He, Evripidis Gavathiotis, Joseph G Sodroski, Loren D Walensky. Proc Natl Acad Sci U S A 2010
197
11

Therapeutic modulation of Notch signalling--are we there yet?
Emma R Andersson, Urban Lendahl. Nat Rev Drug Discov 2014
318
11

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
499
10

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.
Nicholas J Wang, Zachary Sanborn, Kelly L Arnett, Laura J Bayston, Wilson Liao, Charlotte M Proby, Irene M Leigh, Eric A Collisson, Patricia B Gordon, Lakshmi Jakkula,[...]. Proc Natl Acad Sci U S A 2011
315
10

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.
Johan H van Es, Marielle E van Gijn, Orbicia Riccio, Maaike van den Born, Marc Vooijs, Harry Begthel, Miranda Cozijnsen, Sylvie Robine, Doug J Winton, Freddy Radtke,[...]. Nature 2005
10

Notch signalling in context.
Sarah J Bray. Nat Rev Mol Cell Biol 2016
498
10

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.
Roger A Habets, Charles E de Bock, Lutgarde Serneels, Inge Lodewijckx, Delphine Verbeke, David Nittner, Rajeshwar Narlawar, Sofie Demeyer, James Dooley, Adrian Liston,[...]. Sci Transl Med 2019
49
20


Chronic DLL4 blockade induces vascular neoplasms.
Minhong Yan, Christopher A Callahan, Joseph C Beyer, Krishna P Allamneni, Gu Zhang, John Brady Ridgway, Kyle Niessen, Greg D Plowman. Nature 2010
216
9

Deficient T cell fate specification in mice with an induced inactivation of Notch1.
F Radtke, A Wilson, G Stark, M Bauer, J van Meerwijk, H R MacDonald, M Aguet. Immunity 1999
9

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
Miguel Aste-Amézaga, Ningyan Zhang, Janet E Lineberger, Beth A Arnold, Timothy J Toner, Mingcheng Gu, Lingyi Huang, Salvatore Vitelli, Kim T Vo, Peter Haytko,[...]. PLoS One 2010
130
9


Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
Yunsun Nam, Piotr Sliz, Luyan Song, Jon C Aster, Stephen C Blacklow. Cell 2006
319
9

Design and structure of stapled peptides binding to estrogen receptors.
Chris Phillips, Lee R Roberts, Markus Schade, Richard Bazin, Andrew Bent, Nichola L Davies, Rob Moore, Andrew D Pannifer, Andrew R Pickford, Stephen H Prior,[...]. J Am Chem Soc 2011
155
9

Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin.
Tom N Grossmann, Johannes T-H Yeh, Brian R Bowman, Qian Chu, Raymond E Moellering, Gregory L Verdine. Proc Natl Acad Sci U S A 2012
153
9

Design of triazole-stapled BCL9 α-helical peptides to target the β-catenin/B-cell CLL/lymphoma 9 (BCL9) protein-protein interaction.
Steven A Kawamoto, Adriana Coleska, Xu Ran, Han Yi, Chao-Yie Yang, Shaomeng Wang. J Med Chem 2012
152
9

Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia.
Jeremy B Samon, Mireia Castillo-Martin, Michael Hadler, Alberto Ambesi-Impiobato, Elisabeth Paietta, Janis Racevskis, Peter H Wiernik, Jacob M Rowe, John Jakubczak, Sophia Randolph,[...]. Mol Cancer Ther 2012
83
10

Notch signalling in solid tumours: a little bit of everything but not all the time.
Prathibha Ranganathan, Kelly L Weaver, Anthony J Capobianco. Nat Rev Cancer 2011
570
9

Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.
Wan-Ching Yen, Marcus M Fischer, Fumiko Axelrod, Christopher Bond, Jennifer Cain, Belinda Cancilla, William R Henner, Rene Meisner, Aaron Sato, Jalpa Shah,[...]. Clin Cancer Res 2015
164
9


Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer.
Giovanni Roti, Anne Carlton, Kenneth N Ross, Michele Markstein, Kostandin Pajcini, Angela H Su, Norbert Perrimon, Warren S Pear, Andrew L Kung, Stephen C Blacklow,[...]. Cancer Cell 2013
96
9

A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors.
Elena Gabriela Chiorean, Patricia LoRusso, Robert Matthew Strother, Jennifer R Diamond, Anne Younger, Wells A Messersmith, Lieve Adriaens, Liming Liu, Richard J Kao, Albert Thomas DiCioccio,[...]. Clin Cancer Res 2015
82
10


The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.
Rhett A Kovall, Brian Gebelein, David Sprinzak, Raphael Kopan. Dev Cell 2017
174
8

Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
8


A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling.
Alexander M Spokoyny, Yekui Zou, Jingjing J Ling, Hongtao Yu, Yu-Shan Lin, Bradley L Pentelute. J Am Chem Soc 2013
250
8

Structure of the stapled p53 peptide bound to Mdm2.
Sohee Baek, Peter S Kutchukian, Gregory L Verdine, Robert Huber, Tad A Holak, Ki Won Lee, Grzegorz M Popowicz. J Am Chem Soc 2012
146
8

Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.
Marta Pelay-Gimeno, Adrian Glas, Oliver Koch, Tom N Grossmann. Angew Chem Int Ed Engl 2015
343
8

Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis.
Young-Woo Kim, Tom N Grossmann, Gregory L Verdine. Nat Protoc 2011
212
8

Notch signaling is essential for vascular morphogenesis in mice.
L T Krebs, Y Xue, C R Norton, J R Shutter, M Maguire, J P Sundberg, D Gallahan, V Closson, J Kitajewski, R Callahan,[...]. Genes Dev 2000
763
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.