A citation-based method for searching scientific literature

Dorothee Mueller, María-Paz García-Cuéllar, Christian Bach, Sebastian Buhl, Emanuel Maethner, Robert K Slany. PLoS Biol 2009
Times Cited: 148







List of co-cited articles
1099 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification.
Dorothee Mueller, Christian Bach, Deniz Zeisig, Maria-Paz Garcia-Cuellar, Sara Monroe, Arun Sreekumar, Rong Zhou, Alexey Nesvizhskii, Arul Chinnaiyan, Jay L Hess,[...]. Blood 2007
281
49

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.
Chengqi Lin, Edwin R Smith, Hidehisa Takahashi, Ka Chun Lai, Skylar Martin-Brown, Laurence Florens, Michael P Washburn, Joan W Conaway, Ronald C Conaway, Ali Shilatifard. Mol Cell 2010
397
48

A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.
Akihiko Yokoyama, Min Lin, Alpana Naresh, Issay Kitabayashi, Michael L Cleary. Cancer Cell 2010
252
45

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
Kathrin M Bernt, Nan Zhu, Amit U Sinha, Sridhar Vempati, Joerg Faber, Andrei V Krivtsov, Zhaohui Feng, Natalie Punt, Amanda Daigle, Lars Bullinger,[...]. Cancer Cell 2011
590
41

hDOT1L links histone methylation to leukemogenesis.
Yuki Okada, Qin Feng, Yihui Lin, Qi Jiang, Yaqiang Li, Vernon M Coffield, Lishan Su, Guoliang Xu, Yi Zhang. Cell 2005
589
40

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Christina R Majer, Christopher J Sneeringer, Jeffrey Song, L Danielle Johnston, Margaret Porter Scott, Jesse J Smith, Yonghong Xiao,[...]. Cancer Cell 2011
644
39


Potent inhibition of DOT1L as treatment of MLL-fusion leukemia.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Aravind Basavapathruni, Lei Jin, P Ann Boriack-Sjodin, Christina J Allain, Christine R Klaus, Alejandra Raimondi, Margaret Porter Scott,[...]. Blood 2013
457
36

H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
Andrei V Krivtsov, Zhaohui Feng, Madeleine E Lemieux, Joerg Faber, Sridhar Vempati, Amit U Sinha, Xiaobo Xia, Jonathan Jesneck, Adrian P Bracken, Lewis B Silverman,[...]. Cancer Cell 2008
390
35

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom).
Man Mohan, Hans-Martin Herz, Yoh-Hei Takahashi, Chengqi Lin, Ka Chun Lai, Ying Zhang, Michael P Washburn, Laurence Florens, Ali Shilatifard. Genes Dev 2010
210
31

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
David J Steger, Martina I Lefterova, Lei Ying, Aaron J Stonestrom, Michael Schupp, David Zhuo, Adam L Vakoc, Ja-Eun Kim, Junjie Chen, Mitchell A Lazar,[...]. Mol Cell Biol 2008
320
26

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Wenyu Yu, Emma J Chory, Amy K Wernimont, Wolfram Tempel, Alex Scopton, Alexander Federation, Jason J Marineau, Jun Qi, Dalia Barsyte-Lovejoy, Joanna Yi,[...]. Nat Commun 2012
187
26

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain.
Qin Feng, Hengbin Wang, Huck Hui Ng, Hediye Erdjument-Bromage, Paul Tempst, Kevin Struhl, Yi Zhang. Curr Biol 2002
569
26

MLL translocations, histone modifications and leukaemia stem-cell development.
Andrei V Krivtsov, Scott A Armstrong. Nat Rev Cancer 2007
796
26

DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
Anh Tram Nguyen, Olena Taranova, Jin He, Yi Zhang. Blood 2011
179
25

MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.
Sara C Monroe, Stephanie Y Jo, Daniel S Sanders, Venkatesha Basrur, Kojo S Elenitoba-Johnson, Robert K Slany, Jay L Hess. Exp Hematol 2011
60
41

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
Debabrata Biswas, Thomas A Milne, Venkatesha Basrur, Jaehoon Kim, Kojo S J Elenitoba-Johnson, C David Allis, Robert G Roeder. Proc Natl Acad Sci U S A 2011
125
23

The diverse functions of Dot1 and H3K79 methylation.
Anh Tram Nguyen, Yi Zhang. Genes Dev 2011
366
21

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
Mark A Dawson, Rab K Prinjha, Antje Dittmann, George Giotopoulos, Marcus Bantscheff, Wai-In Chan, Samuel C Robson, Chun-wa Chung, Carsten Hopf, Mikhail M Savitski,[...]. Nature 2011
20

Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
Stephanie Y Jo, Eric M Granowicz, Ivan Maillard, Dafydd Thomas, Jay L Hess. Blood 2011
148
20

Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes.
Ming-Jin Chang, Hongyu Wu, Nicholas J Achille, Mary Rose Reisenauer, Chau-Wen Chou, Nancy J Zeleznik-Le, Charles S Hemenway, Wenzheng Zhang. Cancer Res 2010
123
20

The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.
Brendan Jones, Hui Su, Audesh Bhat, Hong Lei, Jeffrey Bajko, Sarah Hevi, Gretchen A Baltus, Shilpa Kadam, Huili Zhai, Reginald Valdez,[...]. PLoS Genet 2008
237
19

The pathogenesis of mixed-lineage leukemia.
Andrew G Muntean, Jay L Hess. Annu Rev Pathol 2012
223
18

MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.
Austin T Thiel, Peter Blessington, Tao Zou, Danielle Feather, Xinjiang Wu, Jizhou Yan, Hui Zhang, Zuguo Liu, Patricia Ernst, Gary A Koretzky,[...]. Cancer Cell 2010
176
17

The molecular biology of mixed lineage leukemia.
Robert K Slany. Haematologica 2009
212
17

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.
Matthew G Guenther, Lee N Lawton, Tatiana Rozovskaia, Garrett M Frampton, Stuart S Levine, Thomas L Volkert, Carlo M Croce, Tatsuya Nakamura, Eli Canaani, Richard A Young. Genes Dev 2008
200
17

The MLL recombinome of acute leukemias in 2013.
C Meyer, J Hofmann, T Burmeister, D Gröger, T S Park, M Emerenciano, M Pombo de Oliveira, A Renneville, P Villarese, E Macintyre,[...]. Leukemia 2013
305
17

MLL targets SET domain methyltransferase activity to Hox gene promoters.
Thomas A Milne, Scott D Briggs, Hugh W Brock, Mary Ellen Martin, Denise Gibbs, C David Allis, Jay L Hess. Mol Cell 2002
786
16

HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP.
Bijan Sobhian, Nadine Laguette, Ahmad Yatim, Mirai Nakamura, Yves Levy, Rosemary Kiernan, Monsef Benkirane. Mol Cell 2010
287
15

Dot1p modulates silencing in yeast by methylation of the nucleosome core.
Fred van Leeuwen, Philip R Gafken, Daniel E Gottschling. Cell 2002
611
15

Conformational adaptation drives potent, selective and durable inhibition of the human protein methyltransferase DOT1L.
Aravind Basavapathruni, Lei Jin, Scott R Daigle, Christina R A Majer, Carly A Therkelsen, Tim J Wigle, Kevin W Kuntz, Richard Chesworth, Roy M Pollock, Margaret P Scott,[...]. Chem Biol Drug Des 2012
96
15

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
Chun-Wei Chen, Richard P Koche, Amit U Sinha, Aniruddha J Deshpande, Nan Zhu, Rowena Eng, John G Doench, Haiming Xu, Scott H Chu, Jun Qi,[...]. Nat Med 2015
142
15

The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.
Akihiko Yokoyama, Tim C P Somervaille, Kevin S Smith, Orit Rozenblatt-Rosen, Matthew Meyerson, Michael L Cleary. Cell 2005
375
14

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Johannes Zuber, Junwei Shi, Eric Wang, Amy R Rappaport, Harald Herrmann, Edward A Sison, Daniel Magoon, Jun Qi, Katharina Blatt, Mark Wunderlich,[...]. Nature 2011
14

Synthesis and structure-activity relationship investigation of adenosine-containing inhibitors of histone methyltransferase DOT1L.
Justin L Anglin, Lisheng Deng, Yuan Yao, Guobin Cai, Zhen Liu, Hong Jiang, Gang Cheng, Pinhong Chen, Shuo Dong, Yongcheng Song. J Med Chem 2012
67
20

Dot1a-AF9 complex mediates histone H3 Lys-79 hypermethylation and repression of ENaCalpha in an aldosterone-sensitive manner.
Wenzheng Zhang, Xuefeng Xia, Mary Rose Reisenauer, Charles S Hemenway, Bruce C Kone. J Biol Chem 2006
129
14

AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
Aniruddha J Deshpande, Anagha Deshpande, Amit U Sinha, Liying Chen, Jenny Chang, Ali Cihan, Maurizio Fazio, Chun-Wei Chen, Nan Zhu, Richard Koche,[...]. Cancer Cell 2014
108
14

Controlling the elongation phase of transcription with P-TEFb.
B Matija Peterlin, David H Price. Mol Cell 2006
812
13

Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis.
Thomas A Milne, Jaehoon Kim, Gang G Wang, Sonja C Stadler, Venkatesha Basrur, Sarah J Whitcomb, Zhanxin Wang, Alexander J Ruthenburg, Kojo S J Elenitoba-Johnson, Robert G Roeder,[...]. Mol Cell 2010
150
13

Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l.
L Chen, A J Deshpande, D Banka, K M Bernt, S Dias, C Buske, E J Olhava, S R Daigle, V M Richon, R M Pollock,[...]. Leukemia 2013
100
13

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.
Aniruddha J Deshpande, Liying Chen, Maurizio Fazio, Amit U Sinha, Kathrin M Bernt, Deepti Banka, Stuart Dias, Jenny Chang, Edward J Olhava, Scott R Daigle,[...]. Blood 2013
118
13


The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.
Andrew G Muntean, Jiaying Tan, Kajal Sitwala, Yongsheng Huang, Joel Bronstein, James A Connelly, Venkatesha Basrur, Kojo S J Elenitoba-Johnson, Jay L Hess. Cancer Cell 2010
159
13

Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin.
Nanhai He, Caleb K Chan, Bijan Sobhian, Seemay Chou, Yuhua Xue, Min Liu, Tom Alber, Monsef Benkirane, Qiang Zhou. Proc Natl Acad Sci U S A 2011
126
13

Selective inhibitors of histone methyltransferase DOT1L: design, synthesis, and crystallographic studies.
Yuan Yao, Pinhong Chen, Jiasheng Diao, Gang Cheng, Lisheng Deng, Justin L Anglin, B V Venkataram Prasad, Yongcheng Song. J Am Chem Soc 2011
118
13


The super elongation complex (SEC) and MLL in development and disease.
Edwin Smith, Chengqi Lin, Ali Shilatifard. Genes Dev 2011
236
12

CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis.
Jiaying Tan, Morgan Jones, Haruhiko Koseki, Manabu Nakayama, Andrew G Muntean, Ivan Maillard, Jay L Hess. Cancer Cell 2011
120
12

Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization.
Bernd B Zeisig, Tom Milne, María-Paz García-Cuéllar, Silke Schreiner, Mary-Ellen Martin, Uta Fuchs, Arndt Borkhardt, Sumit K Chanda, John Walker, Richard Soden,[...]. Mol Cell Biol 2004
246
12



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.