Titia de Lange. Science 2009
Times Cited: 522
Times Cited: 522
Times Cited
Times Co-cited
Similarity
Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
30
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Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
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Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
C B Harley, A B Futcher, C W Greider. Nature 1990
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Alternative lengthening of telomeres: models, mechanisms and implications.
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
15
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
12
A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.
R K Moyzis, J M Buckingham, L S Cram, M Dani, L L Deaven, M D Jones, J Meyne, R L Ratliff, J R Wu. Proc Natl Acad Sci U S A 1988
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Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection.
Elizabeth H Blackburn, Elissa S Epel, Jue Lin. Science 2015
Elizabeth H Blackburn, Elissa S Epel, Jue Lin. Science 2015
12
Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
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Break-induced telomere synthesis underlies alternative telomere maintenance.
Robert L Dilley, Priyanka Verma, Nam Woo Cho, Harrison D Winters, Anne R Wondisford, Roger A Greenberg. Nature 2016
Robert L Dilley, Priyanka Verma, Nam Woo Cho, Harrison D Winters, Anne R Wondisford, Roger A Greenberg. Nature 2016
10
Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies.
Mohammad A Jafri, Shakeel A Ansari, Mohammed H Alqahtani, Jerry W Shay. Genome Med 2016
Mohammad A Jafri, Shakeel A Ansari, Mohammed H Alqahtani, Jerry W Shay. Genome Med 2016
10
A DNA damage checkpoint response in telomere-initiated senescence.
Fabrizio d'Adda di Fagagna, Philip M Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas Von Zglinicki, Gabriele Saretzki, Nigel P Carter, Stephen P Jackson. Nature 2003
Fabrizio d'Adda di Fagagna, Philip M Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas Von Zglinicki, Gabriele Saretzki, Nigel P Carter, Stephen P Jackson. Nature 2003
9
Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes.
Christopher M Heaphy, Andrea P Subhawong, Seung-Mo Hong, Michael G Goggins, Elizabeth A Montgomery, Edward Gabrielson, George J Netto, Jonathan I Epstein, Tamara L Lotan, William H Westra,[...]. Am J Pathol 2011
Christopher M Heaphy, Andrea P Subhawong, Seung-Mo Hong, Michael G Goggins, Elizabeth A Montgomery, Edward Gabrielson, George J Netto, Jonathan I Epstein, Tamara L Lotan, William H Westra,[...]. Am J Pathol 2011
9
Telomeres: protecting chromosomes against genome instability.
Roderick J O'Sullivan, Jan Karlseder. Nat Rev Mol Cell Biol 2010
Roderick J O'Sullivan, Jan Karlseder. Nat Rev Mol Cell Biol 2010
9
Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.
Raymund J Wellinger, Virginia A Zakian. Genetics 2012
Raymund J Wellinger, Virginia A Zakian. Genetics 2012
9
Ageing and the telomere connection: An intimate relationship with inflammation.
Jingwen Zhang, Grishma Rane, Xiaoyun Dai, Muthu K Shanmugam, Frank Arfuso, Ramar Perumal Samy, Mitchell Kim Peng Lai, Dennis Kappei, Alan Prem Kumar, Gautam Sethi. Ageing Res Rev 2016
Jingwen Zhang, Grishma Rane, Xiaoyun Dai, Muthu K Shanmugam, Frank Arfuso, Ramar Perumal Samy, Mitchell Kim Peng Lai, Dennis Kappei, Alan Prem Kumar, Gautam Sethi. Ageing Res Rev 2016
8
Accelerated telomere shortening in response to life stress.
Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Firdaus S Dhabhar, Nancy E Adler, Jason D Morrow, Richard M Cawthon. Proc Natl Acad Sci U S A 2004
Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Firdaus S Dhabhar, Nancy E Adler, Jason D Morrow, Richard M Cawthon. Proc Natl Acad Sci U S A 2004
8
Conservation of the human telomere sequence (TTAGGG)n among vertebrates.
J Meyne, R L Ratliff, R K Moyzis. Proc Natl Acad Sci U S A 1989
J Meyne, R L Ratliff, R K Moyzis. Proc Natl Acad Sci U S A 1989
8
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.
Courtney A Lovejoy, Wendi Li, Steven Reisenweber, Supawat Thongthip, Joanne Bruno, Titia de Lange, Saurav De, John H J Petrini, Patricia A Sung, Maria Jasin,[...]. PLoS Genet 2012
Courtney A Lovejoy, Wendi Li, Steven Reisenweber, Supawat Thongthip, Joanne Bruno, Titia de Lange, Saurav De, John H J Petrini, Patricia A Sung, Maria Jasin,[...]. PLoS Genet 2012
8
Telomere end-replication problem and cell aging.
M Z Levy, R C Allsopp, A B Futcher, C W Greider, C B Harley. J Mol Biol 1992
M Z Levy, R C Allsopp, A B Futcher, C W Greider, C B Harley. J Mol Biol 1992
8
A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon.
A M Olovnikov. J Theor Biol 1973
A M Olovnikov. J Theor Biol 1973
8
Identification of human Rap1: implications for telomere evolution.
B Li, S Oestreich, T de Lange. Cell 2000
B Li, S Oestreich, T de Lange. Cell 2000
8
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
Eros Lazzerini Denchi, Titia de Lange. Nature 2007
Eros Lazzerini Denchi, Titia de Lange. Nature 2007
8
Pot1, the putative telomere end-binding protein in fission yeast and humans.
P Baumann, T R Cech. Science 2001
P Baumann, T R Cech. Science 2001
8
Regulation of telomere length and function by a Myb-domain protein in fission yeast.
J P Cooper, E R Nimmo, R C Allshire, T R Cech. Nature 1997
J P Cooper, E R Nimmo, R C Allshire, T R Cech. Nature 1997
8
The human CST complex is a terminator of telomerase activity.
Liuh-Yow Chen, Sophie Redon, Joachim Lingner. Nature 2012
Liuh-Yow Chen, Sophie Redon, Joachim Lingner. Nature 2012
8
TRF2 protects human telomeres from end-to-end fusions.
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
8
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines.
T M Bryan, A Englezou, L Dalla-Pozza, M A Dunham, R R Reddel. Nat Med 1997
T M Bryan, A Englezou, L Dalla-Pozza, M A Dunham, R R Reddel. Nat Med 1997
8
Obesity, cigarette smoking, and telomere length in women.
A M Valdes, T Andrew, J P Gardner, M Kimura, E Oelsner, L F Cherkas, A Aviv, T D Spector. Lancet 2005
A M Valdes, T Andrew, J P Gardner, M Kimura, E Oelsner, L F Cherkas, A Aviv, T D Spector. Lancet 2005
7
Characterization of oxidative guanine damage and repair in mammalian telomeres.
Zhilong Wang, David B Rhee, Jian Lu, Christina T Bohr, Fang Zhou, Haritha Vallabhaneni, Nadja C de Souza-Pinto, Yie Liu. PLoS Genet 2010
Zhilong Wang, David B Rhee, Jian Lu, Christina T Bohr, Fang Zhou, Haritha Vallabhaneni, Nadja C de Souza-Pinto, Yie Liu. PLoS Genet 2010
7
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.
Claus M Azzalin, Patrick Reichenbach, Lela Khoriauli, Elena Giulotto, Joachim Lingner. Science 2007
Claus M Azzalin, Patrick Reichenbach, Lela Khoriauli, Elena Giulotto, Joachim Lingner. Science 2007
7
The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
7
Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis.
Philip C Haycock, Emma E Heydon, Stephen Kaptoge, Adam S Butterworth, Alex Thompson, Peter Willeit. BMJ 2014
Philip C Haycock, Emma E Heydon, Stephen Kaptoge, Adam S Butterworth, Alex Thompson, Peter Willeit. BMJ 2014
7
The POT1-TPP1 telomere complex is a telomerase processivity factor.
Feng Wang, Elaine R Podell, Arthur J Zaug, Yuting Yang, Paul Baciu, Thomas R Cech, Ming Lei. Nature 2007
Feng Wang, Elaine R Podell, Arthur J Zaug, Yuting Yang, Paul Baciu, Thomas R Cech, Ming Lei. Nature 2007
7
Telomerase Mechanism of Telomere Synthesis.
R Alex Wu, Heather E Upton, Jacob M Vogan, Kathleen Collins. Annu Rev Biochem 2017
R Alex Wu, Heather E Upton, Jacob M Vogan, Kathleen Collins. Annu Rev Biochem 2017
7
Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation.
Ylli Doksani, John Y Wu, Titia de Lange, Xiaowei Zhuang. Cell 2013
Ylli Doksani, John Y Wu, Titia de Lange, Xiaowei Zhuang. Cell 2013
7
Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length.
Tomoichiro Miyoshi, Junko Kanoh, Motoki Saito, Fuyuki Ishikawa. Science 2008
Tomoichiro Miyoshi, Junko Kanoh, Motoki Saito, Fuyuki Ishikawa. Science 2008
7
DNA damage foci at dysfunctional telomeres.
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
7
7
Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2.
Patricia L Opresko, Jinshui Fan, Shamika Danzy, David M Wilson, Vilhelm A Bohr. Nucleic Acids Res 2005
Patricia L Opresko, Jinshui Fan, Shamika Danzy, David M Wilson, Vilhelm A Bohr. Nucleic Acids Res 2005
6
Altered telomeres in tumors with ATRX and DAXX mutations.
Christopher M Heaphy, Roeland F de Wilde, Yuchen Jiao, Alison P Klein, Barish H Edil, Chanjuan Shi, Chetan Bettegowda, Fausto J Rodriguez, Charles G Eberhart, Sachidanand Hebbar,[...]. Science 2011
Christopher M Heaphy, Roeland F de Wilde, Yuchen Jiao, Alison P Klein, Barish H Edil, Chanjuan Shi, Chetan Bettegowda, Fausto J Rodriguez, Charles G Eberhart, Sachidanand Hebbar,[...]. Science 2011
6
Stop pulling my strings - what telomeres taught us about the DNA damage response.
Eros Lazzerini-Denchi, Agnel Sfeir. Nat Rev Mol Cell Biol 2016
Eros Lazzerini-Denchi, Agnel Sfeir. Nat Rev Mol Cell Biol 2016
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.