A citation-based method for searching scientific literature

Andrea Gaedigk, Uwe Fuhr, Charlene Johnson, L Anick Bérard, Dianne Bradford, J Steven Leeder. Pharmacogenomics 2010
Times Cited: 51







List of co-cited articles
576 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.
Andrea Gaedigk, Lazara Karelia Montane Jaime, Joseph S Bertino, Anick Bérard, Victoria M Pratt, L Dianne Bradfordand, J Steven Leeder. Front Pharmacol 2010
50
68

The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.
A Gaedigk, S D Simon, R E Pearce, L D Bradford, M J Kennedy, J S Leeder. Clin Pharmacol Ther 2008
510
60

Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.
A Gaedigk, L Ndjountché, K Divakaran, L Dianne Bradford, I Zineh, T F Oberlander, D C Brousseau, D G McCarver, J A Johnson, S W Alander,[...]. Clin Pharmacol Ther 2007
105
50

CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.
Andrea Gaedigk, Greyson P Twist, J Steven Leeder. Pharmacogenomics 2012
56
49

CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status.
Andrea Gaedigk, L Dianne Bradford, Sarah W Alander, J Steven Leeder. Drug Metab Dispos 2006
72
43

Complexities of CYP2D6 gene analysis and interpretation.
Andrea Gaedigk. Int Rev Psychiatry 2013
138
43



CYP2D6: novel genomic structures and alleles.
Whitney E Kramer, Denise L Walker, Dennis J O'Kane, David A Mrazek, Pamela K Fisher, Brian A Dukek, Jamie K Bruflat, John L Black. Pharmacogenet Genomics 2009
40
42

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors.
J K Hicks, J R Bishop, K Sangkuhl, D J Müller, Y Ji, S G Leckband, J S Leeder, R L Graham, D L Chiulli, A LLerena,[...]. Clin Pharmacol Ther 2015
469
31

The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database.
Andrea Gaedigk, Magnus Ingelman-Sundberg, Neil A Miller, J Steven Leeder, Michelle Whirl-Carrillo, Teri E Klein. Clin Pharmacol Ther 2018
183
31

Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update.
K R Crews, A Gaedigk, H M Dunnenberger, J S Leeder, T E Klein, K E Caudle, C E Haidar, D D Shen, J T Callaghan, S Sadhasivam,[...]. Clin Pharmacol Ther 2014
397
29

Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants.
J K Hicks, J J Swen, C F Thorn, K Sangkuhl, E D Kharasch, V L Ellingrod, T C Skaar, D J Müller, A Gaedigk, J C Stingl. Clin Pharmacol Ther 2013
281
27

Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry.
Ulrich M Zanger, Sebastian Raimundo, Michel Eichelbaum. Naunyn Schmiedebergs Arch Pharmacol 2004
586
25

Discovery of the nonfunctional CYP2D6 31 allele in Spanish, Puerto Rican, and US Hispanic populations.
Andrea Gaedigk, Maria Isidoro-García, Robin E Pearce, Santiago Sánchez, Virginia García-Solaesa, Carolina Lorenzo-Romo, Gloria Gonzalez-Tejera, Susan Corey. Eur J Clin Pharmacol 2010
25
52


Prediction of CYP2D6 phenotype from genotype across world populations.
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri Klein, J Steven Leeder. Genet Med 2017
244
23

Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update.
J K Hicks, K Sangkuhl, J J Swen, V L Ellingrod, D J Müller, K Shimoda, J R Bishop, E D Kharasch, T C Skaar, A Gaedigk,[...]. Clin Pharmacol Ther 2017
246
23

CYP2D6 genotyping for functional-gene dosage analysis by allele copy number detection.
Naoya Hosono, Mamoru Kato, Kazuma Kiyotani, Taisei Mushiroda, Sadaaki Takata, Hiroko Sato, Hanae Amitani, Yumiko Tsuchiya, Keiko Yamazaki, Tatsuhiko Tsunoda,[...]. Clin Chem 2009
62
21

CYP2D6 update: revised nomenclature for CYP2D7/2D6 hybrid genes.
Sarah C Sim, Ann K Daly, Andrea Gaedigk. Pharmacogenet Genomics 2012
17
64

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy.
Matthew P Goetz, Katrin Sangkuhl, Henk-Jan Guchelaar, Matthias Schwab, Michael Province, Michelle Whirl-Carrillo, W Fraser Symmans, Howard L McLeod, Mark J Ratain, Hitoshi Zembutsu,[...]. Clin Pharmacol Ther 2018
144
21

Frequency of undetected CYP2D6 hybrid genes in clinical samples: impact on phenotype prediction.
John Logan Black, Denise L Walker, Dennis J O'Kane, Maria Harmandayan. Drug Metab Dispos 2012
38
26

Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype.
K R Crews, A Gaedigk, H M Dunnenberger, T E Klein, D D Shen, J T Callaghan, E D Kharasch, T C Skaar. Clin Pharmacol Ther 2012
258
19


Functional characterization of CYP2D6 enhancer polymorphisms.
Danxin Wang, Audrey C Papp, Xiaochun Sun. Hum Mol Genet 2015
42
23

Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences.
Greyson P Twist, Andrea Gaedigk, Neil A Miller, Emily G Farrow, Laurel K Willig, Darrell L Dinwiddie, Josh E Petrikin, Sarah E Soden, Suzanne Herd, Margaret Gibson,[...]. NPJ Genom Med 2016
58
19


Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group.
Kelly E Caudle, Katrin Sangkuhl, Michelle Whirl-Carrillo, Jesse J Swen, Cyrine E Haidar, Teri E Klein, Roseann S Gammal, Mary V Relling, Stuart A Scott, Daniel L Hertz,[...]. Clin Transl Sci 2020
169
19

PharmVar GeneFocus: CYP2D6.
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
72
19

Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays.
Anuradha Ramamoorthy, David A Flockhart, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura, Todd C Skaar. Pharmacogenet Genomics 2010
26
34

Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity.
Danxin Wang, Ming J Poi, Xiaochun Sun, Andrea Gaedigk, J Steven Leeder, Wolfgang Sadee. Hum Mol Genet 2014
72
17


Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans.
A Gaedigk, A Bhathena, L Ndjountché, R E Pearce, S M Abdel-Rahman, S W Alander, L DiAnne Bradford, P K Rogan, J Steven Leeder. Pharmacogenomics J 2005
64
15


Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan.
K Abduljalil, D Frank, A Gaedigk, T Klaassen, D Tomalik-Scharte, A Jetter, U Jaehde, J Kirchheiner, U Fuhr. Clin Pharmacol Ther 2010
44
18

Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response.
J Kirchheiner, K Nickchen, M Bauer, M-L Wong, J Licinio, I Roots, J Brockmöller. Mol Psychiatry 2004
495
15

Characterization of the CYP2D6 gene locus and metabolic activity in Indo- and Afro-Trinidadians: discovery of novel allelic variants.
Lazara Karelia Montané Jaime, Anthony Lalla, Werner Steimer, Andrea Gaedigk. Pharmacogenomics 2013
34
23

Pharmacogenetics: from bench to byte--an update of guidelines.
J J Swen, M Nijenhuis, A de Boer, L Grandia, A H Maitland-van der Zee, H Mulder, G A P J M Rongen, R H N van Schaik, T Schalekamp, D J Touw,[...]. Clin Pharmacol Ther 2011
612
15


Long-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6.
Wanqiong Qiao, Yao Yang, Robert Sebra, Geetu Mendiratta, Andrea Gaedigk, Robert J Desnick, Stuart A Scott. Hum Mutat 2016
53
15

Characterization of Reference Materials for Genetic Testing of CYP2D6 Alleles: A GeT-RM Collaborative Project.
Andrea Gaedigk, Amy Turner, Robin E Everts, Stuart A Scott, Praful Aggarwal, Ulrich Broeckel, Gwendolyn A McMillin, Roberta Melis, Erin C Boone, Victoria M Pratt,[...]. J Mol Diagn 2019
26
30

Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine.
I Johansson, E Lundqvist, L Bertilsson, M L Dahl, F Sjöqvist, M Ingelman-Sundberg. Proc Natl Acad Sci U S A 1993
542
13


CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure.
Johanna Sistonen, Antti Sajantila, Oscar Lao, Jukka Corander, Guido Barbujani, Silvia Fuselli. Pharmacogenet Genomics 2007
265
13

A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects.
Sebastian Raimundo, Claudia Toscano, Kathrin Klein, Joachim Fischer, Ernst-Ulrich Griese, Michel Eichelbaum, Matthias Schwab, Ulrich M Zanger. Clin Pharmacol Ther 2004
139
13

Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data.
A Gaedigk, R R Gotschall, N S Forbes, S D Simon, G L Kearns, J S Leeder. Pharmacogenetics 1999
152
13

Ontogeny of dextromethorphan O- and N-demethylation in the first year of life.
M J Blake, A Gaedigk, R E Pearce, L R Bomgaars, M L Christensen, C Stowe, L P James, J T Wilson, G L Kearns, J S Leeder. Clin Pharmacol Ther 2007
115
13

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation.
Ulrich M Zanger, Miia Turpeinen, Kathrin Klein, Matthias Schwab. Anal Bioanal Chem 2008
377
13

Characterization of 107 genomic DNA reference materials for CYP2D6, CYP2C19, CYP2C9, VKORC1, and UGT1A1: a GeT-RM and Association for Molecular Pathology collaborative project.
Victoria M Pratt, Barbara Zehnbauer, Jean Amos Wilson, Ruth Baak, Nikolina Babic, Maria Bettinotti, Arlene Buller, Ken Butz, Matthew Campbell, Chris Civalier,[...]. J Mol Diagn 2010
75
13



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.