A citation-based method for searching scientific literature

Rongbin Zhou, Aubry Tardivel, Bernard Thorens, Inpyo Choi, Jürg Tschopp. Nat Immunol 2010
Times Cited: 1508







List of co-cited articles
942 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
24

The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
766
22

The inflammasomes.
Kate Schroder, Jurg Tschopp. Cell 2010
20


A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
16

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Peter Duewell, Hajime Kono, Katey J Rayner, Cherilyn M Sirois, Gregory Vladimer, Franz G Bauernfeind, George S Abela, Luigi Franchi, Gabriel Nuñez, Max Schnurr,[...]. Nature 2010
15

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling.
Haitao Wen, Denis Gris, Yu Lei, Sushmita Jha, Lu Zhang, Max Tze-Han Huang, Willie June Brickey, Jenny P-Y Ting. Nat Immunol 2011
14

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance.
Bolormaa Vandanmagsar, Yun-Hee Youm, Anthony Ravussin, Jose E Galgani, Krisztian Stadler, Randall L Mynatt, Eric Ravussin, Jacqueline M Stephens, Vishwa Deep Dixit. Nat Med 2011
14

Gout-associated uric acid crystals activate the NALP3 inflammasome.
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
14

Mechanism and Regulation of NLRP3 Inflammasome Activation.
Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
955
14

Targeting the NLRP3 inflammasome in inflammatory diseases.
Matthew S J Mangan, Edward J Olhava, William R Roush, H Martin Seidel, Gary D Glick, Eicke Latz. Nat Rev Drug Discov 2018
385
14

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration.
V Pétrilli, S Papin, C Dostert, A Mayor, F Martinon, J Tschopp. Cell Death Differ 2007
931
14

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
961
14

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Veit Hornung, Franz Bauernfeind, Annett Halle, Eivind O Samstad, Hajime Kono, Kenneth L Rock, Katherine A Fitzgerald, Eicke Latz. Nat Immunol 2008
14

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
13


Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
13

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
Kiichi Nakahira, Jeffrey Adam Haspel, Vijay A K Rathinam, Seon-Jin Lee, Tamas Dolinay, Hilaire C Lam, Joshua A Englert, Marlene Rabinovitch, Manuela Cernadas, Hong Pyo Kim,[...]. Nat Immunol 2011
13

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Kenichi Shimada, Timothy R Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V Krishnan Ramanujan, Andrea J Wolf, Laurent Vergnes, David M Ojcius,[...]. Immunity 2012
13

Mechanisms and functions of inflammasomes.
Mohamed Lamkanfi, Vishva M Dixit. Cell 2014
12

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death.
Jianjin Shi, Wenqing Gao, Feng Shao. Trends Biochem Sci 2017
632
12

Inflammasomes: mechanism of action, role in disease, and therapeutics.
Haitao Guo, Justin B Callaway, Jenny P-Y Ting. Nat Med 2015
11

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.
Yuan He, Melody Y Zeng, Dahai Yang, Benny Motro, Gabriel Núñez. Nature 2016
443
11

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
11

Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome.
Christine M Oslowski, Takashi Hara, Bryan O'Sullivan-Murphy, Kohsuke Kanekura, Simin Lu, Mariko Hara, Shinsuke Ishigaki, Lihua J Zhu, Emiko Hayashi, Simon T Hui,[...]. Cell Metab 2012
407
11

IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.
Alana G Lerner, John-Paul Upton, P V K Praveen, Rajarshi Ghosh, Yoshimi Nakagawa, Aeid Igbaria, Sarah Shen, Vinh Nguyen, Bradley J Backes, Myriam Heiman,[...]. Cell Metab 2012
494
10

Thioredoxin/Txnip: redoxisome, as a redox switch for the pathogenesis of diseases.
Eiji Yoshihara, So Masaki, Yoshiyuki Matsuo, Zhe Chen, Hai Tian, Junji Yodoi. Front Immunol 2014
171
10

Inflammasome is a central player in the induction of obesity and insulin resistance.
Rinke Stienstra, Janna A van Diepen, Cees J Tack, Md Hasan Zaki, Frank L van de Veerdonk, Deshani Perera, Geoffrey A Neale, Guido J Hooiveld, Anneke Hijmans, Irene Vroegrijk,[...]. Proc Natl Acad Sci U S A 2011
445
9

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica.
Catherine Dostert, Virginie Pétrilli, Robin Van Bruggen, Chad Steele, Brooke T Mossman, Jürg Tschopp. Science 2008
9

The inflammasomes: guardians of the body.
Fabio Martinon, Annick Mayor, Jürg Tschopp. Annu Rev Immunol 2009
8

Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes.
Hye-Mi Lee, Jwa-Jin Kim, Hyun Jin Kim, Minho Shong, Bon Jeong Ku, Eun-Kyeong Jo. Diabetes 2013
401
8

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
Seth L Masters, Aisling Dunne, Shoba L Subramanian, Rebecca L Hull, Gillian M Tannahill, Fiona A Sharp, Christine Becker, Luigi Franchi, Eiji Yoshihara, Zhe Chen,[...]. Nat Immunol 2010
842
8

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Annett Halle, Veit Hornung, Gabor C Petzold, Cameron R Stewart, Brian G Monks, Thomas Reinheckel, Katherine A Fitzgerald, Eicke Latz, Kathryn J Moore, Douglas T Golenbock. Nat Immunol 2008
8

Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome.
Humayun Sharif, Li Wang, Wei Li Wang, Venkat Giri Magupalli, Liudmila Andreeva, Qi Qiao, Arthur V Hauenstein, Zhaolong Wu, Gabriel Núñez, Youdong Mao,[...]. Nature 2019
151
8

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.
Nathan Kelley, Devon Jeltema, Yanhui Duan, Yuan He. Int J Mol Sci 2019
439
8

Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.
Hongbin He, Hua Jiang, Yun Chen, Jin Ye, Aoli Wang, Chao Wang, Qingsong Liu, Gaolin Liang, Xianming Deng, Wei Jiang,[...]. Nat Commun 2018
176
8


The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.
Charles L Evavold, Jianbin Ruan, Yunhao Tan, Shiyu Xia, Hao Wu, Jonathan C Kagan. Immunity 2018
363
8

Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation.
Shankar S Iyer, Qiong He, John R Janczy, Eric I Elliott, Zhenyu Zhong, Alicia K Olivier, Jeffrey J Sadler, Vickie Knepper-Adrian, Renzhi Han, Liang Qiao,[...]. Immunity 2013
440
8

K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria.
Christina J Groß, Ritu Mishra, Katharina S Schneider, Guillaume Médard, Jennifer Wettmarshausen, Daniela C Dittlein, Hexin Shi, Oliver Gorka, Paul-Albert Koenig, Stephan Fromm,[...]. Immunity 2016
173
8

Pyroptosis: host cell death and inflammation.
Tessa Bergsbaken, Susan L Fink, Brad T Cookson. Nat Rev Microbiol 2009
8

NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E-Deficient Mice-Brief Report.
Thomas van der Heijden, Eva Kritikou, Wouter Venema, Janine van Duijn, Peter J van Santbrink, Bram Slütter, Amanda C Foks, Ilze Bot, Johan Kuiper. Arterioscler Thromb Vasc Biol 2017
141
8

Cryopyrin activates the inflammasome in response to toxins and ATP.
Sanjeev Mariathasan, David S Weiss, Kim Newton, Jacqueline McBride, Karen O'Rourke, Meron Roose-Girma, Wyne P Lee, Yvette Weinrauch, Denise M Monack, Vishva M Dixit. Nature 2006
8

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity.
Rinke Stienstra, Leo A B Joosten, Tim Koenen, Berry van Tits, Janna A van Diepen, Sjoerd A A van den Berg, Patrick C N Rensen, Peter J Voshol, Giamilla Fantuzzi, Anneke Hijmans,[...]. Cell Metab 2010
425
7

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.
Auvro R Mridha, Alexander Wree, Avril A B Robertson, Matthew M Yeh, Casey D Johnson, Derrick M Van Rooyen, Fahrettin Haczeyni, Narci C-H Teoh, Christopher Savard, George N Ioannou,[...]. J Hepatol 2017
341
7

NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation.
Nan Song, Zhao-Shan Liu, Wen Xue, Zhao-Fang Bai, Qian-Yi Wang, Jiang Dai, Xin Liu, Yi-Jiao Huang, Hong Cai, Xiao-Yan Zhan,[...]. Mol Cell 2017
170
7

Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression.
A Nishiyama, M Matsui, S Iwata, K Hirota, H Masutani, H Nakamura, Y Takagi, H Sono, Y Gon, J Yodoi. J Biol Chem 1999
519
7

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Rebecca C Coll, James R Hill, Christopher J Day, Alina Zamoshnikova, Dave Boucher, Nicholas L Massey, Jessica L Chitty, James A Fraser, Michael P Jennings, Avril A B Robertson,[...]. Nat Chem Biol 2019
197
7

The gasdermins, a protein family executing cell death and inflammation.
Petr Broz, Pablo Pelegrín, Feng Shao. Nat Rev Immunol 2020
159
7

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome.
Takuma Misawa, Michihiro Takahama, Tatsuya Kozaki, Hanna Lee, Jian Zou, Tatsuya Saitoh, Shizuo Akira. Nat Immunol 2013
460
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.