Anna Maria Porcelli, Anna Ghelli, Claudio Ceccarelli, Martin Lang, Giovanna Cenacchi, Mariantonietta Capristo, Lucia Fiammetta Pennisi, Isabella Morra, Enrica Ciccarelli, Antonio Melcarne, Anna Bartoletti-Stella, Nunzio Salfi, Giovanni Tallini, Andrea Martinuzzi, Valerio Carelli, Marcella Attimonelli, Michela Rugolo, Giovanni Romeo, Giuseppe Gasparre. Hum Mol Genet 2010
Times Cited: 91
Times Cited: 91
Times Cited
Times Co-cited
Similarity
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors.
Giuseppe Gasparre, Anna Maria Porcelli, Elena Bonora, Lucia Fiammetta Pennisi, Matteo Toller, Luisa Iommarini, Anna Ghelli, Massimo Moretti, Christine M Betts, Giuseppe Nicola Martinelli,[...]. Proc Natl Acad Sci U S A 2007
Giuseppe Gasparre, Anna Maria Porcelli, Elena Bonora, Lucia Fiammetta Pennisi, Matteo Toller, Luisa Iommarini, Anna Ghelli, Massimo Moretti, Christine M Betts, Giuseppe Nicola Martinelli,[...]. Proc Natl Acad Sci U S A 2007
43
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma.
Giuseppe Gasparre, Eric Hervouet, Elodie de Laplanche, Jocelyne Demont, Lucia Fiammetta Pennisi, Marc Colombel, Florence Mège-Lechevallier, Jean-Yves Scoazec, Elena Bonora, Roel Smeets,[...]. Hum Mol Genet 2008
Giuseppe Gasparre, Eric Hervouet, Elodie de Laplanche, Jocelyne Demont, Lucia Fiammetta Pennisi, Marc Colombel, Florence Mège-Lechevallier, Jean-Yves Scoazec, Elena Bonora, Roel Smeets,[...]. Hum Mol Genet 2008
34
Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III.
Elena Bonora, Anna Maria Porcelli, Giuseppe Gasparre, Annalisa Biondi, Anna Ghelli, Valerio Carelli, Alessandra Baracca, Giovanni Tallini, Andrea Martinuzzi, Giorgio Lenaz,[...]. Cancer Res 2006
Elena Bonora, Anna Maria Porcelli, Giuseppe Gasparre, Annalisa Biondi, Anna Ghelli, Valerio Carelli, Alessandra Baracca, Giovanni Tallini, Andrea Martinuzzi, Giorgio Lenaz,[...]. Cancer Res 2006
30
Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma.
Johannes A Mayr, David Meierhofer, Franz Zimmermann, Rene Feichtinger, Christian Kögler, Manfred Ratschek, Nikolaus Schmeller, Wolfgang Sperl, Barbara Kofler. Clin Cancer Res 2008
Johannes A Mayr, David Meierhofer, Franz Zimmermann, Rene Feichtinger, Christian Kögler, Manfred Ratschek, Nikolaus Schmeller, Wolfgang Sperl, Barbara Kofler. Clin Cancer Res 2008
28
A mutation threshold distinguishes the antitumorigenic effects of the mitochondrial gene MTND1, an oncojanus function.
Giuseppe Gasparre, Ivana Kurelac, Mariantonietta Capristo, Luisa Iommarini, Anna Ghelli, Claudio Ceccarelli, Giordano Nicoletti, Patrizia Nanni, Carla De Giovanni, Katia Scotlandi,[...]. Cancer Res 2011
Giuseppe Gasparre, Ivana Kurelac, Mariantonietta Capristo, Luisa Iommarini, Anna Ghelli, Claudio Ceccarelli, Giordano Nicoletti, Patrizia Nanni, Carla De Giovanni, Katia Scotlandi,[...]. Cancer Res 2011
36
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.
Kaori Ishikawa, Keizo Takenaga, Miho Akimoto, Nobuko Koshikawa, Aya Yamaguchi, Hirotake Imanishi, Kazuto Nakada, Yoshio Honma, Jun-Ichi Hayashi. Science 2008
Kaori Ishikawa, Keizo Takenaga, Miho Akimoto, Nobuko Koshikawa, Aya Yamaguchi, Hirotake Imanishi, Kazuto Nakada, Yoshio Honma, Jun-Ichi Hayashi. Science 2008
24
Learning from oncocytic tumors: Why choose inefficient mitochondria?
Giuseppe Gasparre, Giovanni Romeo, Michela Rugolo, Anna Maria Porcelli. Biochim Biophys Acta 2011
Giuseppe Gasparre, Giovanni Romeo, Michela Rugolo, Anna Maria Porcelli. Biochim Biophys Acta 2011
25
A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis.
Jeong Soon Park, Lokendra Kumar Sharma, Hongzhi Li, Ruihua Xiang, Deborah Holstein, Jun Wu, James Lechleiter, Susan L Naylor, Janice J Deng, Jianxin Lu,[...]. Hum Mol Genet 2009
Jeong Soon Park, Lokendra Kumar Sharma, Hongzhi Li, Ruihua Xiang, Deborah Holstein, Jun Wu, James Lechleiter, Susan L Naylor, Janice J Deng, Jianxin Lu,[...]. Hum Mol Genet 2009
23
mtDNA mutations increase tumorigenicity in prostate cancer.
John A Petros, Amanda K Baumann, Eduardo Ruiz-Pesini, Mahul B Amin, Carrie Qi Sun, John Hall, SoDug Lim, Muta M Issa, W Dana Flanders, Seyed H Hosseini,[...]. Proc Natl Acad Sci U S A 2005
John A Petros, Amanda K Baumann, Eduardo Ruiz-Pesini, Mahul B Amin, Carrie Qi Sun, John Hall, SoDug Lim, Muta M Issa, W Dana Flanders, Seyed H Hosseini,[...]. Proc Natl Acad Sci U S A 2005
21
Somatic complex I disruptive mitochondrial DNA mutations are modifiers of tumorigenesis that correlate with low genomic instability in pituitary adenomas.
Ivana Kurelac, Alan MacKay, Maryou B K Lambros, Erica Di Cesare, Giovanna Cenacchi, Claudio Ceccarelli, Isabella Morra, Antonio Melcarne, Luca Morandi, Francesco Maria Calabrese,[...]. Hum Mol Genet 2013
Ivana Kurelac, Alan MacKay, Maryou B K Lambros, Erica Di Cesare, Giovanna Cenacchi, Claudio Ceccarelli, Isabella Morra, Antonio Melcarne, Luca Morandi, Francesco Maria Calabrese,[...]. Hum Mol Genet 2013
45
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells.
Giuseppe Gasparre, Luisa Iommarini, Anna Maria Porcelli, Martin Lang, Gian Gaetano Ferri, Ivana Kurelac, Roberta Zuntini, Elisa Mariani, Lucia Fiammetta Pennisi, Ernesto Pasquini,[...]. Hum Mutat 2009
Giuseppe Gasparre, Luisa Iommarini, Anna Maria Porcelli, Martin Lang, Gian Gaetano Ferri, Ivana Kurelac, Roberta Zuntini, Elisa Mariani, Lucia Fiammetta Pennisi, Ernesto Pasquini,[...]. Hum Mutat 2009
44
Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis.
Yujiro Shidara, Kumi Yamagata, Takashi Kanamori, Kazutoshi Nakano, Jennifer Q Kwong, Giovanni Manfredi, Hideaki Oda, Shigeo Ohta. Cancer Res 2005
Yujiro Shidara, Kumi Yamagata, Takashi Kanamori, Kazutoshi Nakano, Jennifer Q Kwong, Giovanni Manfredi, Hideaki Oda, Shigeo Ohta. Cancer Res 2005
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Somatic mutations of the mitochondrial genome in human colorectal tumours.
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17
Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells.
Claudia Calabrese, Luisa Iommarini, Ivana Kurelac, Maria Antonietta Calvaruso, Mariantonietta Capristo, Pier-Luigi Lollini, Patrizia Nanni, Christian Bergamini, Giordano Nicoletti, Carla De Giovanni,[...]. Cancer Metab 2013
Claudia Calabrese, Luisa Iommarini, Ivana Kurelac, Maria Antonietta Calvaruso, Mariantonietta Capristo, Pier-Luigi Lollini, Patrizia Nanni, Christian Bergamini, Giordano Nicoletti, Carla De Giovanni,[...]. Cancer Metab 2013
27
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment.
Luisa Iommarini, Ivana Kurelac, Mariantonietta Capristo, Maria Antonietta Calvaruso, Valentina Giorgio, Christian Bergamini, Anna Ghelli, Patrizia Nanni, Carla De Giovanni, Valerio Carelli,[...]. Hum Mol Genet 2014
Luisa Iommarini, Ivana Kurelac, Mariantonietta Capristo, Maria Antonietta Calvaruso, Valentina Giorgio, Christian Bergamini, Anna Ghelli, Patrizia Nanni, Carla De Giovanni, Valerio Carelli,[...]. Hum Mol Genet 2014
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Mitochondrial DNA mutations in oxyphilic and chief cell parathyroid adenomas.
Jessica Costa-Guda, Takehiko Tokura, Sanford I Roth, Andrew Arnold. BMC Endocr Disord 2007
Jessica Costa-Guda, Takehiko Tokura, Sanford I Roth, Andrew Arnold. BMC Endocr Disord 2007
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Complex I impairment in mitochondrial diseases and cancer: parallel roads leading to different outcomes.
Luisa Iommarini, Maria Antonietta Calvaruso, Ivana Kurelac, Giuseppe Gasparre, Anna Maria Porcelli. Int J Biochem Cell Biol 2013
Luisa Iommarini, Maria Antonietta Calvaruso, Ivana Kurelac, Giuseppe Gasparre, Anna Maria Porcelli. Int J Biochem Cell Biol 2013
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Relevance of mitochondrial genetics and metabolism in cancer development.
Giuseppe Gasparre, Anna Maria Porcelli, Giorgio Lenaz, Giovanni Romeo. Cold Spring Harb Perspect Biol 2013
Giuseppe Gasparre, Anna Maria Porcelli, Giorgio Lenaz, Giovanni Romeo. Cold Spring Harb Perspect Biol 2013
20
Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors.
Valdemar Máximo, Paula Soares, Jorge Lima, José Cameselle-Teijeiro, Manuel Sobrinho-Simões. Am J Pathol 2002
Valdemar Máximo, Paula Soares, Jorge Lima, José Cameselle-Teijeiro, Manuel Sobrinho-Simões. Am J Pathol 2002
15
Lack of complex I is associated with oncocytic thyroid tumours.
F A Zimmermann, J A Mayr, D Neureiter, R Feichtinger, B Alinger, N D Jones, W Eder, W Sperl, B Kofler. Br J Cancer 2009
F A Zimmermann, J A Mayr, D Neureiter, R Feichtinger, B Alinger, N D Jones, W Eder, W Sperl, B Kofler. Br J Cancer 2009
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Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase.
Mary A Selak, Sean M Armour, Elaine D MacKenzie, Houda Boulahbel, David G Watson, Kyle D Mansfield, Yi Pan, M Celeste Simon, Craig B Thompson, Eyal Gottlieb. Cancer Cell 2005
Mary A Selak, Sean M Armour, Elaine D MacKenzie, Houda Boulahbel, David G Watson, Kyle D Mansfield, Yi Pan, M Celeste Simon, Craig B Thompson, Eyal Gottlieb. Cancer Cell 2005
13
Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma.
Wenyue Sun, Shaoyu Zhou, Steven S Chang, Thomas McFate, Ajay Verma, Joseph A Califano. Clin Cancer Res 2009
Wenyue Sun, Shaoyu Zhou, Steven S Chang, Thomas McFate, Ajay Verma, Joseph A Califano. Clin Cancer Res 2009
15
Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors.
Luísa Pereira, Pedro Soares, Valdemar Máximo, David C Samuels. BMC Cancer 2012
Luísa Pereira, Pedro Soares, Valdemar Máximo, David C Samuels. BMC Cancer 2012
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Molecular features of thyroid oncocytic tumors.
Giuseppe Gasparre, Elena Bonora, Giovanni Tallini, Giovanni Romeo. Mol Cell Endocrinol 2010
Giuseppe Gasparre, Elena Bonora, Giovanni Tallini, Giovanni Romeo. Mol Cell Endocrinol 2010
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Sequence and organization of the human mitochondrial genome.
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Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells.
Katarína Smolková, Lydie Plecitá-Hlavatá, Nadége Bellance, Giovanni Benard, Rodrigue Rossignol, Petr Ježek. Int J Biochem Cell Biol 2011
Katarína Smolková, Lydie Plecitá-Hlavatá, Nadége Bellance, Giovanni Benard, Rodrigue Rossignol, Petr Ježek. Int J Biochem Cell Biol 2011
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Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA.
R M Andrews, I Kubacka, P F Chinnery, R N Lightowlers, D M Turnbull, N Howell. Nat Genet 1999
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Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck.
Shaoyu Zhou, Sushant Kachhap, Wenyue Sun, Guojun Wu, Alice Chuang, Luana Poeta, Lawson Grumbine, Suhail K Mithani, Aditi Chatterjee, Wayne Koch,[...]. Proc Natl Acad Sci U S A 2007
Shaoyu Zhou, Sushant Kachhap, Wenyue Sun, Guojun Wu, Alice Chuang, Luana Poeta, Lawson Grumbine, Suhail K Mithani, Aditi Chatterjee, Wayne Koch,[...]. Proc Natl Acad Sci U S A 2007
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Heteroplasmic mitochondrial DNA mutations in normal and tumour cells.
Yiping He, Jian Wu, Devin C Dressman, Christine Iacobuzio-Donahue, Sanford D Markowitz, Victor E Velculescu, Luis A Diaz, Kenneth W Kinzler, Bert Vogelstein, Nickolas Papadopoulos. Nature 2010
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10
Facile detection of mitochondrial DNA mutations in tumors and bodily fluids.
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10
Respiratory chain complex I is a mitochondrial tumor suppressor of oncocytic tumors.
Franz A Zimmermann, Johannes A Mayr, Rene Feichtinger, Daniel Neureiter, Roman Lechner, Christian Koegler, Manfred Ratschek, Husic Rusmir, Karine Sargsyan, Wolfgang Sperl,[...]. Front Biosci (Elite Ed) 2011
Franz A Zimmermann, Johannes A Mayr, Rene Feichtinger, Daniel Neureiter, Roman Lechner, Christian Koegler, Manfred Ratschek, Husic Rusmir, Karine Sargsyan, Wolfgang Sperl,[...]. Front Biosci (Elite Ed) 2011
26
HmtDB, a genomic resource for mitochondrion-based human variability studies.
Francesco Rubino, Roberta Piredda, Francesco Maria Calabrese, Domenico Simone, Martin Lang, Claudia Calabrese, Vittoria Petruzzella, Mila Tommaseo-Ponzetta, Giuseppe Gasparre, Marcella Attimonelli. Nucleic Acids Res 2012
Francesco Rubino, Roberta Piredda, Francesco Maria Calabrese, Domenico Simone, Martin Lang, Claudia Calabrese, Vittoria Petruzzella, Mila Tommaseo-Ponzetta, Giuseppe Gasparre, Marcella Attimonelli. Nucleic Acids Res 2012
14
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer.
Young Seok Ju, Ludmil B Alexandrov, Moritz Gerstung, Inigo Martincorena, Serena Nik-Zainal, Manasa Ramakrishna, Helen R Davies, Elli Papaemmanuil, Gunes Gundem, Adam Shlien,[...]. Elife 2014
Young Seok Ju, Ludmil B Alexandrov, Moritz Gerstung, Inigo Martincorena, Serena Nik-Zainal, Manasa Ramakrishna, Helen R Davies, Elli Papaemmanuil, Gunes Gundem, Adam Shlien,[...]. Elife 2014
10
Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations.
P J Pollard, J J Brière, N A Alam, J Barwell, E Barclay, N C Wortham, T Hunt, M Mitchell, S Olpin, S J Moat,[...]. Hum Mol Genet 2005
P J Pollard, J J Brière, N A Alam, J Barwell, E Barclay, N C Wortham, T Hunt, M Mitchell, S Olpin, S J Moat,[...]. Hum Mol Genet 2005
9
9
Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation.
Mannis van Oven, Manfred Kayser. Hum Mutat 2009
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Human mitochondrial DNA: roles of inherited and somatic mutations.
Eric A Schon, Salvatore DiMauro, Michio Hirano. Nat Rev Genet 2012
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Detection of mitochondrial DNA mutations in pancreatic cancer offers a "mass"-ive advantage over detection of nuclear DNA mutations.
J B Jones, J J Song, P M Hempen, G Parmigiani, R H Hruban, S E Kern. Cancer Res 2001
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8
8
Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels.
Anna Maria Porcelli, Alessia Angelin, Anna Ghelli, Elisa Mariani, Andrea Martinuzzi, Valerio Carelli, Valeria Petronilli, Paolo Bernardi, Michela Rugolo. J Biol Chem 2009
Anna Maria Porcelli, Alessia Angelin, Anna Ghelli, Elisa Mariani, Andrea Martinuzzi, Valerio Carelli, Valeria Petronilli, Paolo Bernardi, Michela Rugolo. J Biol Chem 2009
10
Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.
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8
Mitochondrial complex I is deficient in renal oncocytomas.
Helene Simonnet, Jocelyne Demont, Kathy Pfeiffer, Leila Guenaneche, Raymonde Bouvier, Ulrich Brandt, Hermann Schagger, Catherine Godinot. Carcinogenesis 2003
Helene Simonnet, Jocelyne Demont, Kathy Pfeiffer, Leila Guenaneche, Raymonde Bouvier, Ulrich Brandt, Hermann Schagger, Catherine Godinot. Carcinogenesis 2003
8
Somatic mutations of mitochondrial genome in hepatocellular carcinoma.
Pen-Hui Yin, Cheng-Chung Wu, Jin-Ching Lin, Chin-Wen Chi, Yau-Huei Wei, Hsin-Chen Lee. Mitochondrion 2010
Pen-Hui Yin, Cheng-Chung Wu, Jin-Ching Lin, Chin-Wen Chi, Yau-Huei Wei, Hsin-Chen Lee. Mitochondrion 2010
12
Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis.
Jianxin Lu, Lokendra Kumar Sharma, Yidong Bai. Cell Res 2009
Jianxin Lu, Lokendra Kumar Sharma, Yidong Bai. Cell Res 2009
8
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia.
Jung-whan Kim, Irina Tchernyshyov, Gregg L Semenza, Chi V Dang. Cell Metab 2006
Jung-whan Kim, Irina Tchernyshyov, Gregg L Semenza, Chi V Dang. Cell Metab 2006
8
Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Andrew R Mullen, William W Wheaton, Eunsook S Jin, Pei-Hsuan Chen, Lucas B Sullivan, Tzuling Cheng, Youfeng Yang, W Marston Linehan, Navdeep S Chandel, Ralph J DeBerardinis. Nature 2011
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8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.