Nan Su, Qidi Sun, Can Li, Xiumin Lu, Huabing Qi, Siyu Chen, Jing Yang, Xiaolan Du, Ling Zhao, Qifen He, Min Jin, Yue Shen, Di Chen, Lin Chen. Hum Mol Genet 2010
Times Cited: 66
Times Cited: 66
Times Cited
Times Co-cited
Similarity
Fibroblast growth factor receptor 3 is a negative regulator of bone growth.
C Deng, A Wynshaw-Boris, F Zhou, A Kuo, P Leder. Cell 1996
C Deng, A Wynshaw-Boris, F Zhou, A Kuo, P Leder. Cell 1996
39
Defective bone mineralization and osteopenia in young adult FGFR3-/- mice.
Gladys Valverde-Franco, Hanlong Liu, David Davidson, Sen Chai, Hector Valderrama-Carvajal, David Goltzman, David M Ornitz, Janet E Henderson. Hum Mol Genet 2004
Gladys Valverde-Franco, Hanlong Liu, David Davidson, Sen Chai, Hector Valderrama-Carvajal, David Goltzman, David M Ornitz, Janet E Henderson. Hum Mol Genet 2004
33
Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis.
L Chen, R Adar, X Yang, E O Monsonego, C Li, P V Hauschka, A Yayon, C X Deng. J Clin Invest 1999
L Chen, R Adar, X Yang, E O Monsonego, C Li, P V Hauschka, A Yayon, C X Deng. J Clin Invest 1999
31
Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3.
M C Naski, J S Colvin, J D Coffin, D M Ornitz. Development 1998
M C Naski, J S Colvin, J D Coffin, D M Ornitz. Development 1998
28
A Ser(365)-->Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia.
L Chen, C Li, W Qiao, X Xu, C Deng. Hum Mol Genet 2001
L Chen, C Li, W Qiao, X Xu, C Deng. Hum Mol Genet 2001
28
FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease.
David M Ornitz, Pierre J Marie. Genes Dev 2002
David M Ornitz, Pierre J Marie. Genes Dev 2002
27
Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia.
F Rousseau, J Bonaventure, L Legeai-Mallet, A Pelet, J M Rozet, P Maroteaux, M Le Merrer, A Munnich. Nature 1994
F Rousseau, J Bonaventure, L Legeai-Mallet, A Pelet, J M Rozet, P Maroteaux, M Le Merrer, A Munnich. Nature 1994
27
FGFR3 promotes synchondrosis closure and fusion of ossification centers through the MAPK pathway.
Takehiko Matsushita, William R Wilcox, Yuk Yu Chan, Aya Kawanami, Hülya Bükülmez, Gener Balmes, Pavel Krejci, Pertchoui B Mekikian, Kazuyuki Otani, Isakichi Yamaura,[...]. Hum Mol Genet 2009
Takehiko Matsushita, William R Wilcox, Yuk Yu Chan, Aya Kawanami, Hülya Bükülmez, Gener Balmes, Pavel Krejci, Pertchoui B Mekikian, Kazuyuki Otani, Isakichi Yamaura,[...]. Hum Mol Genet 2009
25
A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos.
T Iwata, L Chen, C Li, D A Ovchinnikov, R R Behringer, C A Francomano, C X Deng. Hum Mol Genet 2000
T Iwata, L Chen, C Li, D A Ovchinnikov, R R Behringer, C A Francomano, C X Deng. Hum Mol Genet 2000
25
A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis.
Liangjun Yin, Xiaolan Du, Cuiling Li, Xiaoling Xu, Zhi Chen, Nan Su, Ling Zhao, Huabing Qi, Fubing Li, Jing Xue,[...]. Bone 2008
Liangjun Yin, Xiaolan Du, Cuiling Li, Xiaoling Xu, Zhi Chen, Nan Su, Ling Zhao, Huabing Qi, Fubing Li, Jing Xue,[...]. Bone 2008
22
Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation.
Anne L Jacob, Craig Smith, Juha Partanen, David M Ornitz. Dev Biol 2006
Anne L Jacob, Craig Smith, Juha Partanen, David M Ornitz. Dev Biol 2006
22
Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia.
R Shiang, L M Thompson, Y Z Zhu, D M Church, T J Fielder, M Bocian, S T Winokur, J J Wasmuth. Cell 1994
R Shiang, L M Thompson, Y Z Zhu, D M Church, T J Fielder, M Bocian, S T Winokur, J J Wasmuth. Cell 1994
22
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.
J S Colvin, B A Bohne, G W Harding, D G McEwen, D M Ornitz. Nat Genet 1996
J S Colvin, B A Bohne, G W Harding, D G McEwen, D M Ornitz. Nat Genet 1996
22
A novel mutation in FGFR3 causes camptodactyly, tall stature, and hearing loss (CATSHL) syndrome.
Reha M Toydemir, Anna E Brassington, Pinar Bayrak-Toydemir, Patrycja A Krakowiak, Lynn B Jorde, Frank G Whitby, Nicola Longo, David H Viskochil, John C Carey, Michael J Bamshad. Am J Hum Genet 2006
Reha M Toydemir, Anna E Brassington, Pinar Bayrak-Toydemir, Patrycja A Krakowiak, Lynn B Jorde, Frank G Whitby, Nicola Longo, David H Viskochil, John C Carey, Michael J Bamshad. Am J Hum Genet 2006
22
Skeletal analysis of the Fgfr3(P244R) mouse, a genetic model for the Muenke craniosynostosis syndrome.
Stephen R F Twigg, Chris Healy, Christian Babbs, Jacqueline A Sharpe, William G Wood, Paul T Sharpe, Gillian M Morriss-Kay, Andrew O M Wilkie. Dev Dyn 2009
Stephen R F Twigg, Chris Healy, Christian Babbs, Jacqueline A Sharpe, William G Wood, Paul T Sharpe, Gillian M Morriss-Kay, Andrew O M Wilkie. Dev Dyn 2009
21
Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse.
Yingli Wang, Ran Xiao, Fan Yang, Baktiar O Karim, Anthony J Iacovelli, Juanliang Cai, Charles P Lerner, Joan T Richtsmeier, Jen M Leszl, Cheryl A Hill,[...]. Development 2005
Yingli Wang, Ran Xiao, Fan Yang, Baktiar O Karim, Anthony J Iacovelli, Juanliang Cai, Charles P Lerner, Joan T Richtsmeier, Jen M Leszl, Cheryl A Hill,[...]. Development 2005
19
RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis.
Vivek Shukla, Xavier Coumoul, Rui-Hong Wang, Hyun-Seok Kim, Chu-Xia Deng. Nat Genet 2007
Vivek Shukla, Xavier Coumoul, Rui-Hong Wang, Hyun-Seok Kim, Chu-Xia Deng. Nat Genet 2007
19
Spatio-temporal expression of FGFR 1, 2 and 3 genes during human embryo-fetal ossification.
A L Delezoide, C Benoist-Lasselin, L Legeai-Mallet, M Le Merrer, A Munnich, M Vekemans, J Bonaventure. Mech Dev 1998
A L Delezoide, C Benoist-Lasselin, L Legeai-Mallet, M Le Merrer, A Munnich, M Vekemans, J Bonaventure. Mech Dev 1998
19
A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors.
C Li, L Chen, T Iwata, M Kitagawa, X Y Fu, C X Deng. Hum Mol Genet 1999
C Li, L Chen, T Iwata, M Kitagawa, X Y Fu, C X Deng. Hum Mol Genet 1999
19
Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype.
Shunichi Murakami, Gener Balmes, Sandra McKinney, Zhaoping Zhang, David Givol, Benoit de Crombrugghe. Genes Dev 2004
Shunichi Murakami, Gener Balmes, Sandra McKinney, Zhaoping Zhang, David Givol, Benoit de Crombrugghe. Genes Dev 2004
19
An activating Fgfr3 mutation affects trabecular bone formation via a paracrine mechanism during growth.
Emilie Mugniery, Romain Dacquin, Caroline Marty, Catherine Benoist-Lasselin, Marie-Christine de Vernejoul, Pierre Jurdic, Arnold Munnich, Valérie Geoffroy, Laurence Legeai-Mallet. Hum Mol Genet 2012
Emilie Mugniery, Romain Dacquin, Caroline Marty, Catherine Benoist-Lasselin, Marie-Christine de Vernejoul, Pierre Jurdic, Arnold Munnich, Valérie Geoffroy, Laurence Legeai-Mallet. Hum Mol Genet 2012
38
Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation.
A Montero, Y Okada, M Tomita, M Ito, H Tsurukami, T Nakamura, T Doetschman, J D Coffin, M M Hurley. J Clin Invest 2000
A Montero, Y Okada, M Tomita, M Ito, H Tsurukami, T Nakamura, T Doetschman, J D Coffin, M M Hurley. J Clin Invest 2000
18
FGF signaling in the developing endochondral skeleton.
David M Ornitz. Cytokine Growth Factor Rev 2005
David M Ornitz. Cytokine Growth Factor Rev 2005
18
Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway.
Akihiro Yasoda, Yasato Komatsu, Hideki Chusho, Takashi Miyazawa, Ami Ozasa, Masako Miura, Tatsuya Kurihara, Tomohiro Rogi, Shoji Tanaka, Michio Suda,[...]. Nat Med 2004
Akihiro Yasoda, Yasato Komatsu, Hideki Chusho, Takashi Miyazawa, Ami Ozasa, Masako Miura, Tatsuya Kurihara, Tomohiro Rogi, Shoji Tanaka, Michio Suda,[...]. Nat Med 2004
18
Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3.
P L Tavormina, R Shiang, L M Thompson, Y Z Zhu, D J Wilkin, R S Lachman, W R Wilcox, D L Rimoin, D H Cohn, J J Wasmuth. Nat Genet 1995
P L Tavormina, R Shiang, L M Thompson, Y Z Zhu, D J Wilkin, R S Lachman, W R Wilcox, D L Rimoin, D H Cohn, J J Wasmuth. Nat Genet 1995
18
Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse model recapitulating achondroplasia.
Florence Lorget, Nabil Kaci, Jeff Peng, Catherine Benoist-Lasselin, Emilie Mugniery, Todd Oppeneer, Dan J Wendt, Sean M Bell, Sherry Bullens, Stuart Bunting,[...]. Am J Hum Genet 2012
Florence Lorget, Nabil Kaci, Jeff Peng, Catherine Benoist-Lasselin, Emilie Mugniery, Todd Oppeneer, Dan J Wendt, Sean M Bell, Sherry Bullens, Stuart Bunting,[...]. Am J Hum Genet 2012
18
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth.
Kai Yu, Jingsong Xu, Zhonghao Liu, Drazen Sosic, Jiansu Shao, Eric N Olson, Dwight A Towler, David M Ornitz. Development 2003
Kai Yu, Jingsong Xu, Zhonghao Liu, Drazen Sosic, Jiansu Shao, Eric N Olson, Dwight A Towler, David M Ornitz. Development 2003
16
FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis.
Norihiko Ohbayashi, Masaki Shibayama, Yoko Kurotaki, Mayumi Imanishi, Toshihiko Fujimori, Nobuyuki Itoh, Shinji Takada. Genes Dev 2002
Norihiko Ohbayashi, Masaki Shibayama, Yoko Kurotaki, Mayumi Imanishi, Toshihiko Fujimori, Nobuyuki Itoh, Shinji Takada. Genes Dev 2002
16
Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18.
Zhonghao Liu, Jingsong Xu, Jennifer S Colvin, David M Ornitz. Genes Dev 2002
Zhonghao Liu, Jingsong Xu, Jennifer S Colvin, David M Ornitz. Genes Dev 2002
16
Stat1 controls postnatal bone formation by regulating fibroblast growth factor signaling in osteoblasts.
Liping Xiao, Takahiro Naganawa, Eneze Obugunde, Gloria Gronowicz, David M Ornitz, J Douglas Coffin, Marja M Hurley. J Biol Chem 2004
Liping Xiao, Takahiro Naganawa, Eneze Obugunde, Gloria Gronowicz, David M Ornitz, J Douglas Coffin, Marja M Hurley. J Biol Chem 2004
16
A Pro250Arg substitution in mouse Fgfr1 causes increased expression of Cbfa1 and premature fusion of calvarial sutures.
Y X Zhou, X Xu, L Chen, C Li, S G Brodie, C X Deng. Hum Mol Genet 2000
Y X Zhou, X Xu, L Chen, C Li, S G Brodie, C X Deng. Hum Mol Genet 2000
15
Integration of FGF and TWIST in calvarial bone and suture development.
D P Rice, T Aberg, Y Chan, Z Tang, P J Kettunen, L Pakarinen, R E Maxson, I Thesleff. Development 2000
D P Rice, T Aberg, Y Chan, Z Tang, P J Kettunen, L Pakarinen, R E Maxson, I Thesleff. Development 2000
15
Fibroblast growth factor receptor 3 (FGFR3) transmembrane mutation in Crouzon syndrome with acanthosis nigricans.
G A Meyers, S J Orlow, I R Munro, K A Przylepa, E W Jabs. Nat Genet 1995
G A Meyers, S J Orlow, I R Munro, K A Przylepa, E W Jabs. Nat Genet 1995
15
Activating Fgfr3 Y367C mutation causes hearing loss and inner ear defect in a mouse model of chondrodysplasia.
Stéphanie Pannier, Vincent Couloigner, Nadia Messaddeq, Monique Elmaleh-Bergès, Arnold Munnich, Raymond Romand, Laurence Legeai-Mallet. Biochim Biophys Acta 2009
Stéphanie Pannier, Vincent Couloigner, Nadia Messaddeq, Monique Elmaleh-Bergès, Arnold Munnich, Raymond Romand, Laurence Legeai-Mallet. Biochim Biophys Acta 2009
25
Skeletal overgrowth is mediated by deficiency in a specific isoform of fibroblast growth factor receptor 3.
Veraragavan P Eswarakumar, Joseph Schlessinger. Proc Natl Acad Sci U S A 2007
Veraragavan P Eswarakumar, Joseph Schlessinger. Proc Natl Acad Sci U S A 2007
22
A unique point mutation in the fibroblast growth factor receptor 3 gene (FGFR3) defines a new craniosynostosis syndrome.
M Muenke, K W Gripp, D M McDonald-McGinn, K Gaudenz, L A Whitaker, S P Bartlett, R I Markowitz, N H Robin, N Nwokoro, J J Mulvihill,[...]. Am J Hum Genet 1997
M Muenke, K W Gripp, D M McDonald-McGinn, K Gaudenz, L A Whitaker, S P Bartlett, R I Markowitz, N H Robin, N Nwokoro, J J Mulvihill,[...]. Am J Hum Genet 1997
15
A Ser252Trp [corrected] substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis.
Lin Chen, Dan Li, Cuiling Li, April Engel, Chu-Xia Deng. Bone 2003
Lin Chen, Dan Li, Cuiling Li, April Engel, Chu-Xia Deng. Bone 2003
15
Highly activated Fgfr3 with the K644M mutation causes prolonged survival in severe dwarf mice.
T Iwata, C L Li, C X Deng, C A Francomano. Hum Mol Genet 2001
T Iwata, C L Li, C X Deng, C A Francomano. Hum Mol Genet 2001
15
A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3.
Y Wang, M K Spatz, K Kannan, H Hayk, A Avivi, M Gorivodsky, M Pines, A Yayon, P Lonai, D Givol. Proc Natl Acad Sci U S A 1999
Y Wang, M K Spatz, K Kannan, H Hayk, A Avivi, M Gorivodsky, M Pines, A Yayon, P Lonai, D Givol. Proc Natl Acad Sci U S A 1999
15
Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism.
W C Su, M Kitagawa, N Xue, B Xie, S Garofalo, J Cho, C Deng, W A Horton, X Y Fu. Nature 1997
W C Su, M Kitagawa, N Xue, B Xie, S Garofalo, J Cho, C Deng, W A Horton, X Y Fu. Nature 1997
15
Role of FGFs/FGFRs in skeletal development and bone regeneration.
Xiaolan Du, Yangli Xie, Cory J Xian, Lin Chen. J Cell Physiol 2012
Xiaolan Du, Yangli Xie, Cory J Xian, Lin Chen. J Cell Physiol 2012
15
Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation.
Alka Mansukhani, Davide Ambrosetti, Greg Holmes, Lizbeth Cornivelli, Claudio Basilico. J Cell Biol 2005
Alka Mansukhani, Davide Ambrosetti, Greg Holmes, Lizbeth Cornivelli, Claudio Basilico. J Cell Biol 2005
13
Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts.
A Mansukhani, P Bellosta, M Sahni, C Basilico. J Cell Biol 2000
A Mansukhani, P Bellosta, M Sahni, C Basilico. J Cell Biol 2000
13
Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation.
Eleonora Minina, Conny Kreschel, Michael C Naski, David M Ornitz, Andrea Vortkamp. Dev Cell 2002
Eleonora Minina, Conny Kreschel, Michael C Naski, David M Ornitz, Andrea Vortkamp. Dev Cell 2002
13
Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis.
K Peters, D Ornitz, S Werner, L Williams. Dev Biol 1993
K Peters, D Ornitz, S Werner, L Williams. Dev Biol 1993
13
Sixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias.
Silvie Foldynova-Trantirkova, William R Wilcox, Pavel Krejci. Hum Mutat 2012
Silvie Foldynova-Trantirkova, William R Wilcox, Pavel Krejci. Hum Mutat 2012
13
Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice.
Stéphanie Garcia, Béatrice Dirat, Thomas Tognacci, Nathalie Rochet, Xavier Mouska, Stéphanie Bonnafous, Stéphanie Patouraux, Albert Tran, Philippe Gual, Yannick Le Marchand-Brustel,[...]. Sci Transl Med 2013
Stéphanie Garcia, Béatrice Dirat, Thomas Tognacci, Nathalie Rochet, Xavier Mouska, Stéphanie Bonnafous, Stéphanie Patouraux, Albert Tran, Philippe Gual, Yannick Le Marchand-Brustel,[...]. Sci Transl Med 2013
15
FGFR3 mutation causes abnormal membranous ossification in achondroplasia.
Federico Di Rocco, Martin Biosse Duplan, Yann Heuzé, Nabil Kaci, Davide Komla-Ebri, Arnold Munnich, Emilie Mugniery, Catherine Benoist-Lasselin, Laurence Legeai-Mallet. Hum Mol Genet 2014
Federico Di Rocco, Martin Biosse Duplan, Yann Heuzé, Nabil Kaci, Davide Komla-Ebri, Arnold Munnich, Emilie Mugniery, Catherine Benoist-Lasselin, Laurence Legeai-Mallet. Hum Mol Genet 2014
24
Deletion of FGFR3 in Osteoclast Lineage Cells Results in Increased Bone Mass in Mice by Inhibiting Osteoclastic Bone Resorption.
Nan Su, Xiaogang Li, Yubin Tang, Jing Yang, Xuan Wen, Jingyuan Guo, Junzhou Tang, Xiaolan Du, Lin Chen. J Bone Miner Res 2016
Nan Su, Xiaogang Li, Yubin Tang, Jing Yang, Xuan Wen, Jingyuan Guo, Junzhou Tang, Xiaolan Du, Lin Chen. J Bone Miner Res 2016
52
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.