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Times Cited
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Similarity
The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
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A complex secretory program orchestrated by the inflammasome controls paracrine senescence.
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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.
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A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
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Cellular Senescence: Defining a Path Forward.
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An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
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Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
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Cellular senescence: from physiology to pathology.
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Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.
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A proteomic atlas of senescence-associated secretomes for aging biomarker development.
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Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.
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Senolytics improve physical function and increase lifespan in old age.
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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a.
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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.
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Chemokine signaling via the CXCR2 receptor reinforces senescence.
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Programmed cell senescence during mammalian embryonic development.
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The essence of senescence.
Thomas Kuilman, Chrysiis Michaloglou, Wolter J Mooi, Daniel S Peeper. Genes Dev 2010
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Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease.
LaTonya J Hickson, Larissa G P Langhi Prata, Shane A Bobart, Tamara K Evans, Nino Giorgadze, Shahrukh K Hashmi, Sandra M Herrmann, Michael D Jensen, Qingyi Jia, Kyra L Jordan,[...]. EBioMedicine 2019
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Senescence and aging: Causes, consequences, and therapeutic avenues.
Domhnall McHugh, Jesús Gil. J Cell Biol 2018
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Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases.
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Cellular senescence: when bad things happen to good cells.
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A DNA damage checkpoint response in telomere-initiated senescence.
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Hallmarks of Cellular Senescence.
Alejandra Hernandez-Segura, Jamil Nehme, Marco Demaria. Trends Cell Biol 2018
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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.
Wen Xue, Lars Zender, Cornelius Miething, Ross A Dickins, Eva Hernando, Valery Krizhanovsky, Carlos Cordon-Cardo, Scott W Lowe. Nature 2007
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Senescence is a developmental mechanism that contributes to embryonic growth and patterning.
Mekayla Storer, Alba Mas, Alexandre Robert-Moreno, Matteo Pecoraro, M Carmen Ortells, Valeria Di Giacomo, Reut Yosef, Noam Pilpel, Valery Krizhanovsky, James Sharpe,[...]. Cell 2013
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Lamin B1 loss is a senescence-associated biomarker.
Adam Freund, Remi-Martin Laberge, Marco Demaria, Judith Campisi. Mol Biol Cell 2012
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Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline.
Tyler J Bussian, Asef Aziz, Charlton F Meyer, Barbara L Swenson, Jan M van Deursen, Darren J Baker. Nature 2018
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Ink4a/Arf expression is a biomarker of aging.
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Senescence-associated reprogramming promotes cancer stemness.
Maja Milanovic, Dorothy N Y Fan, Dimitri Belenki, J Henry M Däbritz, Zhen Zhao, Yong Yu, Jan R Dörr, Lora Dimitrova, Dido Lenze, Ines A Monteiro Barbosa,[...]. Nature 2018
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12
NOTCH1 mediates a switch between two distinct secretomes during senescence.
Matthew Hoare, Yoko Ito, Tae-Won Kang, Michael P Weekes, Nicholas J Matheson, Daniel A Patten, Shishir Shetty, Aled J Parry, Suraj Menon, Rafik Salama,[...]. Nat Cell Biol 2016
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Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Zhixun Dou, Kanad Ghosh, Maria Grazia Vizioli, Jiajun Zhu, Payel Sen, Kirk J Wangensteen, Johayra Simithy, Yemin Lan, Yanping Lin, Zhuo Zhou,[...]. Nature 2017
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Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse.
Marco Demaria, Monique N O'Leary, Jianhui Chang, Lijian Shao, Su Liu, Fatouma Alimirah, Kristin Koenig, Catherine Le, Natalia Mitin, Allison M Deal,[...]. Cancer Discov 2017
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Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
Francis Rodier, Jean-Philippe Coppé, Christopher K Patil, Wieteke A M Hoeijmakers, Denise P Muñoz, Saba R Raza, Adam Freund, Eric Campeau, Albert R Davalos, Judith Campisi. Nat Cell Biol 2009
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Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.
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Unmasking Transcriptional Heterogeneity in Senescent Cells.
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Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
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Targeting cellular senescence prevents age-related bone loss in mice.
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MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
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Senescent cells: an emerging target for diseases of ageing.
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Inflamm-aging. An evolutionary perspective on immunosenescence.
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Senescence of activated stellate cells limits liver fibrosis.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.