Hiroshi Hibino, Atsushi Inanobe, Kazuharu Furutani, Shingo Murakami, Ian Findlay, Yoshihisa Kurachi. Physiol Rev 2010
Times Cited: 884
Times Cited: 884
Times Cited
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Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease.
Christian Lüscher, Paul A Slesinger. Nat Rev Neurosci 2010
Christian Lüscher, Paul A Slesinger. Nat Rev Neurosci 2010
10
Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma.
C L Huang, S Feng, D W Hilgemann. Nature 1998
C L Huang, S Feng, D W Hilgemann. Nature 1998
9
Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium.
Matthew R Whorton, Roderick MacKinnon. Cell 2011
Matthew R Whorton, Roderick MacKinnon. Cell 2011
9
The role of glial-specific Kir4.1 in normal and pathological states of the CNS.
Sinifunanya E Nwaobi, Vishnu A Cuddapah, Kelsey C Patterson, Anita C Randolph, Michelle L Olsen. Acta Neuropathol 2016
Sinifunanya E Nwaobi, Vishnu A Cuddapah, Kelsey C Patterson, Anita C Randolph, Michelle L Olsen. Acta Neuropathol 2016
8
Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation.
Biljana Djukic, Kristen B Casper, Benjamin D Philpot, Lih-Shen Chin, Ken D McCarthy. J Neurosci 2007
Biljana Djukic, Kristen B Casper, Benjamin D Philpot, Lih-Shen Chin, Ken D McCarthy. J Neurosci 2007
8
The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins.
G Krapivinsky, E A Gordon, K Wickman, B Velimirović, L Krapivinsky, D E Clapham. Nature 1995
G Krapivinsky, E A Gordon, K Wickman, B Velimirović, L Krapivinsky, D E Clapham. Nature 1995
7
Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2.
Scott B Hansen, Xiao Tao, Roderick MacKinnon. Nature 2011
Scott B Hansen, Xiao Tao, Roderick MacKinnon. Nature 2011
7
Molecular background of leak K+ currents: two-pore domain potassium channels.
Péter Enyedi, Gábor Czirják. Physiol Rev 2010
Péter Enyedi, Gábor Czirják. Physiol Rev 2010
7
Functional implications for Kir4.1 channels in glial biology: from K+ buffering to cell differentiation.
Michelle L Olsen, Harald Sontheimer. J Neurochem 2008
Michelle L Olsen, Harald Sontheimer. J Neurochem 2008
6
Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 A resolution.
Xiao Tao, Jose L Avalos, Jiayun Chen, Roderick MacKinnon. Science 2009
Xiao Tao, Jose L Avalos, Jiayun Chen, Roderick MacKinnon. Science 2009
6
X-ray structure of the mammalian GIRK2-βγ G-protein complex.
Matthew R Whorton, Roderick MacKinnon. Nature 2013
Matthew R Whorton, Roderick MacKinnon. Nature 2013
6
pH dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia.
S J Tucker, P Imbrici, L Salvatore, M C D'Adamo, M Pessia. J Biol Chem 2000
S J Tucker, P Imbrici, L Salvatore, M C D'Adamo, M Pessia. J Biol Chem 2000
5
Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice.
Xiaoping Tong, Yan Ao, Guido C Faas, Sinifunanya E Nwaobi, Ji Xu, Martin D Haustein, Mark A Anderson, Istvan Mody, Michelle L Olsen, Michael V Sofroniew,[...]. Nat Neurosci 2014
Xiaoping Tong, Yan Ao, Guido C Faas, Sinifunanya E Nwaobi, Ji Xu, Martin D Haustein, Mark A Anderson, Istvan Mody, Michelle L Olsen, Michael V Sofroniew,[...]. Nat Neurosci 2014
5
G protein regulation of potassium ion channels.
M Yamada, A Inanobe, Y Kurachi. Pharmacol Rev 1998
M Yamada, A Inanobe, Y Kurachi. Pharmacol Rev 1998
5
Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297.
Nicole Wydeven, Ezequiel Marron Fernandez de Velasco, Yu Du, Michael A Benneyworth, Matthew C Hearing, Rachel A Fischer, Mark John Thomas, C David Weaver, Kevin Wickman. Proc Natl Acad Sci U S A 2014
Nicole Wydeven, Ezequiel Marron Fernandez de Velasco, Yu Du, Michael A Benneyworth, Matthew C Hearing, Rachel A Fischer, Mark John Thomas, C David Weaver, Kevin Wickman. Proc Natl Acad Sci U S A 2014
7
K(+) channels: function-structural overview.
Carlos González, David Baez-Nieto, Ignacio Valencia, Ingrid Oyarzún, Patricio Rojas, David Naranjo, Ramón Latorre. Compr Physiol 2012
Carlos González, David Baez-Nieto, Ignacio Valencia, Ingrid Oyarzún, Patricio Rojas, David Naranjo, Ramón Latorre. Compr Physiol 2012
5
KCNJ10 gene mutations causing EAST syndrome (epilepsy, ataxia, sensorineural deafness, and tubulopathy) disrupt channel function.
Markus Reichold, Anselm A Zdebik, Evelyn Lieberer, Markus Rapedius, Katharina Schmidt, Sascha Bandulik, Christina Sterner, Ines Tegtmeier, David Penton, Thomas Baukrowitz,[...]. Proc Natl Acad Sci U S A 2010
Markus Reichold, Anselm A Zdebik, Evelyn Lieberer, Markus Rapedius, Katharina Schmidt, Sascha Bandulik, Christina Sterner, Ines Tegtmeier, David Penton, Thomas Baukrowitz,[...]. Proc Natl Acad Sci U S A 2010
5
5
Role of inward rectifier potassium channels in salivary gland function and sugar feeding of the fruit fly, Drosophila melanogaster.
Daniel R Swale, Zhilin Li, Felix Guerrero, Adalberto A Pérez De León, Lane D Foil. Pestic Biochem Physiol 2017
Daniel R Swale, Zhilin Li, Felix Guerrero, Adalberto A Pérez De León, Lane D Foil. Pestic Biochem Physiol 2017
27
Inward rectifier potassium (Kir) channels mediate salivary gland function and blood feeding in the lone star tick, Amblyomma americanum.
Zhilin Li, Kevin R Macaluso, Lane D Foil, Daniel R Swale. PLoS Negl Trop Dis 2019
Zhilin Li, Kevin R Macaluso, Lane D Foil, Daniel R Swale. PLoS Negl Trop Dis 2019
55
Inwardly rectifying K+ (Kir) channels in Drosophila. A crucial role of cellular milieu factors Kir channel function.
Frank Döring, Erhard Wischmeyer, Ronald P Kühnlein, Herbert Jäckle, Andreas Karschin. J Biol Chem 2002
Frank Döring, Erhard Wischmeyer, Ronald P Kühnlein, Herbert Jäckle, Andreas Karschin. J Biol Chem 2002
12
Block of Kir channels by flonicamid disrupts salivary and renal excretion of insect pests.
Miaomiao Ren, Jianguo Niu, Bo Hu, Qi Wei, Cheng Zheng, Xiangrui Tian, Congfen Gao, Bingjun He, Ke Dong, Jianya Su. Insect Biochem Mol Biol 2018
Miaomiao Ren, Jianguo Niu, Bo Hu, Qi Wei, Cheng Zheng, Xiangrui Tian, Congfen Gao, Bingjun He, Ke Dong, Jianya Su. Insect Biochem Mol Biol 2018
27
Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels.
Rene Raphemot, Matthew F Rouhier, Daniel R Swale, Emily Days, C David Weaver, Kimberly M Lovell, Leah C Konkel, Darren W Engers, Sean R Bollinger, Corey Hopkins,[...]. PLoS One 2014
Rene Raphemot, Matthew F Rouhier, Daniel R Swale, Emily Days, C David Weaver, Kimberly M Lovell, Leah C Konkel, Darren W Engers, Sean R Bollinger, Corey Hopkins,[...]. PLoS One 2014
14
An insecticide resistance-breaking mosquitocide targeting inward rectifier potassium channels in vectors of Zika virus and malaria.
Daniel R Swale, Darren W Engers, Sean R Bollinger, Aaron Gross, Edna Alfaro Inocente, Emily Days, Fariba Kanga, Reed M Johnson, Liu Yang, Jeffrey R Bloomquist,[...]. Sci Rep 2016
Daniel R Swale, Darren W Engers, Sean R Bollinger, Aaron Gross, Edna Alfaro Inocente, Emily Days, Fariba Kanga, Reed M Johnson, Liu Yang, Jeffrey R Bloomquist,[...]. Sci Rep 2016
13
The inward rectifier current (IK1) controls cardiac excitability and is involved in arrhythmogenesis.
Amit S Dhamoon, José Jalife. Heart Rhythm 2005
Amit S Dhamoon, José Jalife. Heart Rhythm 2005
5
Synthesis of a stable form of tertiapin: a high-affinity inhibitor for inward-rectifier K+ channels.
W Jin, Z Lu. Biochemistry 1999
W Jin, Z Lu. Biochemistry 1999
5
ATP-sensitive potassium channelopathies: focus on insulin secretion.
Frances M Ashcroft. J Clin Invest 2005
Frances M Ashcroft. J Clin Invest 2005
5
Disease Associated Mutations in KIR Proteins Linked to Aberrant Inward Rectifier Channel Trafficking.
Eva-Maria Zangerl-Plessl, Muge Qile, Meye Bloothooft, Anna Stary-Weinzinger, Marcel A G van der Heyden. Biomolecules 2019
Eva-Maria Zangerl-Plessl, Muge Qile, Meye Bloothooft, Anna Stary-Weinzinger, Marcel A G van der Heyden. Biomolecules 2019
50
ATP-Sensitive Potassium Channels and Their Physiological and Pathophysiological Roles.
Andrew Tinker, Qadeer Aziz, Yiwen Li, Mark Specterman. Compr Physiol 2018
Andrew Tinker, Qadeer Aziz, Yiwen Li, Mark Specterman. Compr Physiol 2018
8
Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart.
Nathalie Gaborit, Sabrina Le Bouter, Viktoria Szuts, Andras Varro, Denis Escande, Stanley Nattel, Sophie Demolombe. J Physiol 2007
Nathalie Gaborit, Sabrina Le Bouter, Viktoria Szuts, Andras Varro, Denis Escande, Stanley Nattel, Sophie Demolombe. J Physiol 2007
5
Diabetes and insulin secretion: the ATP-sensitive K+ channel (K ATP) connection.
Joseph C Koster, M Alan Permutt, Colin G Nichols. Diabetes 2005
Joseph C Koster, M Alan Permutt, Colin G Nichols. Diabetes 2005
4
4
Proteomics. Tissue-based map of the human proteome.
Mathias Uhlén, Linn Fagerberg, Björn M Hallström, Cecilia Lindskog, Per Oksvold, Adil Mardinoglu, Åsa Sivertsson, Caroline Kampf, Evelina Sjöstedt, Anna Asplund,[...]. Science 2015
Mathias Uhlén, Linn Fagerberg, Björn M Hallström, Cecilia Lindskog, Per Oksvold, Adil Mardinoglu, Åsa Sivertsson, Caroline Kampf, Evelina Sjöstedt, Anna Asplund,[...]. Science 2015
4
Heterogeneity of Kir4.1 channel expression in glia revealed by mouse transgenesis.
Xiaofang Tang, Kenichiro Taniguchi, Paulo Kofuji. Glia 2009
Xiaofang Tang, Kenichiro Taniguchi, Paulo Kofuji. Glia 2009
9
Astroglial Kir4.1 in the lateral habenula drives neuronal bursts in depression.
Yihui Cui, Yan Yang, Zheyi Ni, Yiyan Dong, Guohong Cai, Alexandre Foncelle, Shuangshuang Ma, Kangning Sang, Siyang Tang, Yuezhou Li,[...]. Nature 2018
Yihui Cui, Yan Yang, Zheyi Ni, Yiyan Dong, Guohong Cai, Alexandre Foncelle, Shuangshuang Ma, Kangning Sang, Siyang Tang, Yuezhou Li,[...]. Nature 2018
4
Biophysical and pharmacological characterization of inwardly rectifying K+ currents in rat spinal cord astrocytes.
C B Ransom, H Sontheimer. J Neurophysiol 1995
C B Ransom, H Sontheimer. J Neurophysiol 1995
4
Differential assembly of inwardly rectifying K+ channel subunits, Kir4.1 and Kir5.1, in brain astrocytes.
Hiroshi Hibino, Akikazu Fujita, Kaori Iwai, Mitsuhiko Yamada, Yoshihisa Kurachi. J Biol Chem 2004
Hiroshi Hibino, Akikazu Fujita, Kaori Iwai, Mitsuhiko Yamada, Yoshihisa Kurachi. J Biol Chem 2004
4
DNA methylation functions as a critical regulator of Kir4.1 expression during CNS development.
Sinifunanya E Nwaobi, Erica Lin, Sasank R Peramsetty, Michelle L Olsen. Glia 2014
Sinifunanya E Nwaobi, Erica Lin, Sasank R Peramsetty, Michelle L Olsen. Glia 2014
10
Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1.
M Pessia, P Imbrici, M C D'Adamo, L Salvatore, S J Tucker. J Physiol 2001
M Pessia, P Imbrici, M C D'Adamo, L Salvatore, S J Tucker. J Physiol 2001
4
G protein-activated inwardly rectifying potassium channels mediate depotentiation of long-term potentiation.
Hee Jung Chung, Woo-Ping Ge, Xiang Qian, Ofer Wiser, Yuh Nung Jan, Lily Yeh Jan. Proc Natl Acad Sci U S A 2009
Hee Jung Chung, Woo-Ping Ge, Xiang Qian, Ofer Wiser, Yuh Nung Jan, Lily Yeh Jan. Proc Natl Acad Sci U S A 2009
5
ML297 (VU0456810), the first potent and selective activator of the GIRK potassium channel, displays antiepileptic properties in mice.
Kristian Kaufmann, Ian Romaine, Emily Days, Conrado Pascual, Adam Malik, Liya Yang, Bende Zou, Yu Du, Greg Sliwoski, Ryan D Morrison,[...]. ACS Chem Neurosci 2013
Kristian Kaufmann, Ian Romaine, Emily Days, Conrado Pascual, Adam Malik, Liya Yang, Bende Zou, Yu Du, Greg Sliwoski, Ryan D Morrison,[...]. ACS Chem Neurosci 2013
4
New insights into the therapeutic potential of Girk channels.
Rafael Luján, Ezequiel Marron Fernandez de Velasco, Carolina Aguado, Kevin Wickman. Trends Neurosci 2014
Rafael Luján, Ezequiel Marron Fernandez de Velasco, Carolina Aguado, Kevin Wickman. Trends Neurosci 2014
4
G Protein-Gated Potassium Channels: A Link to Drug Addiction.
Robert A Rifkin, Stephen J Moss, Paul A Slesinger. Trends Pharmacol Sci 2017
Robert A Rifkin, Stephen J Moss, Paul A Slesinger. Trends Pharmacol Sci 2017
13
Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification.
A N Lopatin, E N Makhina, C G Nichols. Nature 1994
A N Lopatin, E N Makhina, C G Nichols. Nature 1994
4
International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.
George A Gutman, K George Chandy, Stephan Grissmer, Michel Lazdunski, David McKinnon, Luis A Pardo, Gail A Robertson, Bernardo Rudy, Michael C Sanguinetti, Walter Stühmer,[...]. Pharmacol Rev 2005
George A Gutman, K George Chandy, Stephan Grissmer, Michel Lazdunski, David McKinnon, Luis A Pardo, Gail A Robertson, Bernardo Rudy, Michael C Sanguinetti, Walter Stühmer,[...]. Pharmacol Rev 2005
4
CLC Chloride Channels and Transporters: Structure, Function, Physiology, and Disease.
Thomas J Jentsch, Michael Pusch. Physiol Rev 2018
Thomas J Jentsch, Michael Pusch. Physiol Rev 2018
4
Alterations in conserved Kir channel-PIP2 interactions underlie channelopathies.
Coeli M B Lopes, Hailin Zhang, Tibor Rohacs, Taihao Jin, Jian Yang, Diomedes E Logothetis. Neuron 2002
Coeli M B Lopes, Hailin Zhang, Tibor Rohacs, Taihao Jin, Jian Yang, Diomedes E Logothetis. Neuron 2002
4
Specificity of activation by phosphoinositides determines lipid regulation of Kir channels.
Tibor Rohács, Coeli M B Lopes, Taihao Jin, Pavan P Ramdya, Zoltán Molnár, Diomedes E Logothetis. Proc Natl Acad Sci U S A 2003
Tibor Rohács, Coeli M B Lopes, Taihao Jin, Pavan P Ramdya, Zoltán Molnár, Diomedes E Logothetis. Proc Natl Acad Sci U S A 2003
4
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.