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Times Cited: 1706
Times Cited: 1706
Times Cited
Times Co-cited
Similarity
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.
Noriyuki Matsuda, Shigeto Sato, Kahori Shiba, Kei Okatsu, Keiko Saisho, Clement A Gautier, Yu-Shin Sou, Shinji Saiki, Sumihiro Kawajiri, Fumiaki Sato,[...]. J Cell Biol 2010
Noriyuki Matsuda, Shigeto Sato, Kahori Shiba, Kei Okatsu, Keiko Saisho, Clement A Gautier, Yu-Shin Sou, Shinji Saiki, Sumihiro Kawajiri, Fumiaki Sato,[...]. J Cell Biol 2010
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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
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Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.
Lei Liu, Du Feng, Guo Chen, Ming Chen, Qiaoxia Zheng, Pingping Song, Qi Ma, Chongzhuo Zhu, Rui Wang, Wanjun Qi,[...]. Nat Cell Biol 2012
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Hereditary early-onset Parkinson's disease caused by mutations in PINK1.
Enza Maria Valente, Patrick M Abou-Sleiman, Viviana Caputo, Miratul M K Muqit, Kirsten Harvey, Suzana Gispert, Zeeshan Ali, Domenico Del Turco, Anna Rita Bentivoglio, Daniel G Healy,[...]. Science 2004
Enza Maria Valente, Patrick M Abou-Sleiman, Viviana Caputo, Miratul M K Muqit, Kirsten Harvey, Suzana Gispert, Zeeshan Ali, Domenico Del Turco, Anna Rita Bentivoglio, Daniel G Healy,[...]. Science 2004
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The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease.
Alicia M Pickrell, Richard J Youle. Neuron 2015
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Ubiquitin is phosphorylated by PINK1 to activate parkin.
Fumika Koyano, Kei Okatsu, Hidetaka Kosako, Yasushi Tamura, Etsu Go, Mayumi Kimura, Yoko Kimura, Hikaru Tsuchiya, Hidehito Yoshihara, Takatsugu Hirokawa,[...]. Nature 2014
Fumika Koyano, Kei Okatsu, Hidetaka Kosako, Yasushi Tamura, Etsu Go, Mayumi Kimura, Yoko Kimura, Hikaru Tsuchiya, Hidehito Yoshihara, Takatsugu Hirokawa,[...]. Nature 2014
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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
T Kitada, S Asakawa, N Hattori, H Matsumine, Y Yamamura, S Minoshima, M Yokochi, Y Mizuno, N Shimizu. Nature 1998
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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.
Chandana Kondapalli, Agne Kazlauskaite, Ning Zhang, Helen I Woodroof, David G Campbell, Robert Gourlay, Lynn Burchell, Helen Walden, Thomas J Macartney, Maria Deak,[...]. Open Biol 2012
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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
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PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
Cristofol Vives-Bauza, Chun Zhou, Yong Huang, Mei Cui, Rosa L A de Vries, Jiho Kim, Jessica May, Maja Aleksandra Tocilescu, Wencheng Liu, Han Seok Ko,[...]. Proc Natl Acad Sci U S A 2010
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Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
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Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.
Agne Kazlauskaite, Chandana Kondapalli, Robert Gourlay, David G Campbell, Maria Stella Ritorto, Kay Hofmann, Dario R Alessi, Axel Knebel, Matthias Trost, Miratul M K Muqit. Biochem J 2014
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Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.
Seok Min Jin, Michael Lazarou, Chunxin Wang, Lesley A Kane, Derek P Narendra, Richard J Youle. J Cell Biol 2010
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Parkin and PINK1 mitigate STING-induced inflammation.
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
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Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.
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NIX is required for programmed mitochondrial clearance during reticulocyte maturation.
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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin.
Atsushi Tanaka, Megan M Cleland, Shan Xu, Derek P Narendra, Der-Fen Suen, Mariusz Karbowski, Richard J Youle. J Cell Biol 2010
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Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation.
Tomokazu Murakawa, Osamu Yamaguchi, Ayako Hashimoto, Shungo Hikoso, Toshihiro Takeda, Takafumi Oka, Hiroki Yasui, Hiromichi Ueda, Yasuhiro Akazawa, Hiroyuki Nakayama,[...]. Nat Commun 2015
Tomokazu Murakawa, Osamu Yamaguchi, Ayako Hashimoto, Shungo Hikoso, Toshihiro Takeda, Takafumi Oka, Hiroki Yasui, Hiromichi Ueda, Yasuhiro Akazawa, Hiroyuki Nakayama,[...]. Nat Commun 2015
10
Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin.
Ghazaleh Ashrafi, Julia S Schlehe, Matthew J LaVoie, Thomas L Schwarz. J Cell Biol 2014
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PINK1/Parkin-mediated mitophagy in mammalian cells.
Akinori Eiyama, Koji Okamoto. Curr Opin Cell Biol 2015
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Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand.
Thomas G McWilliams, Alan R Prescott, Lambert Montava-Garriga, Graeme Ball, François Singh, Erica Barini, Miratul M K Muqit, Simon P Brooks, Ian G Ganley. Cell Metab 2018
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The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy.
Jin-Mi Heo, Alban Ordureau, Joao A Paulo, Jesse Rinehart, J Wade Harper. Mol Cell 2015
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Essential role for Nix in autophagic maturation of erythroid cells.
Hector Sandoval, Perumal Thiagarajan, Swapan K Dasgupta, Armin Schumacher, Josef T Prchal, Min Chen, Jin Wang. Nature 2008
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Mechanisms of mitophagy in cellular homeostasis, physiology and pathology.
Konstantinos Palikaras, Eirini Lionaki, Nektarios Tavernarakis. Nat Cell Biol 2018
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The pathways of mitophagy for quality control and clearance of mitochondria.
G Ashrafi, T L Schwarz. Cell Death Differ 2013
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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.
Ira E Clark, Mark W Dodson, Changan Jiang, Joseph H Cao, Jun R Huh, Jae Hong Seol, Soon Ji Yoo, Bruce A Hay, Ming Guo. Nature 2006
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Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.
Yvette C Wong, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2014
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Nix is a selective autophagy receptor for mitochondrial clearance.
Ivana Novak, Vladimir Kirkin, David G McEwan, Ji Zhang, Philipp Wild, Alexis Rozenknop, Vladimir Rogov, Frank Löhr, Doris Popovic, Angelo Occhipinti,[...]. EMBO Rep 2010
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Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor.
Yongjie Wei, Wei-Chung Chiang, Rhea Sumpter, Prashant Mishra, Beth Levine. Cell 2017
Yongjie Wei, Wei-Chung Chiang, Rhea Sumpter, Prashant Mishra, Beth Levine. Cell 2017
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Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells.
Charleen T Chu, Jing Ji, Ruben K Dagda, Jian Fei Jiang, Yulia Y Tyurina, Alexandr A Kapralov, Vladimir A Tyurin, Naveena Yanamala, Indira H Shrivastava, Dariush Mohammadyani,[...]. Nat Cell Biol 2013
Charleen T Chu, Jing Ji, Ruben K Dagda, Jian Fei Jiang, Yulia Y Tyurina, Alexandr A Kapralov, Vladimir A Tyurin, Naveena Yanamala, Indira H Shrivastava, Dariush Mohammadyani,[...]. Nat Cell Biol 2013
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PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
Yun Chen, Gerald W Dorn. Science 2013
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FKBP8 recruits LC3A to mediate Parkin-independent mitophagy.
Zambarlal Bhujabal, Åsa B Birgisdottir, Eva Sjøttem, Hanne B Brenne, Aud Øvervatn, Sabrina Habisov, Vladimir Kirkin, Trond Lamark, Terje Johansen. EMBO Rep 2017
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PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy.
Kahori Shiba-Fukushima, Yuzuru Imai, Shigeharu Yoshida, Yasushi Ishihama, Tomoko Kanao, Shigeto Sato, Nobutaka Hattori. Sci Rep 2012
Kahori Shiba-Fukushima, Yuzuru Imai, Shigeharu Yoshida, Yasushi Ishihama, Tomoko Kanao, Shigeto Sato, Nobutaka Hattori. Sci Rep 2012
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Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy.
Matthew E Gegg, J Mark Cooper, Kai-Yin Chau, Manuel Rojo, Anthony H V Schapira, Jan-Willem Taanman. Hum Mol Genet 2010
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PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility.
Xinnan Wang, Dominic Winter, Ghazaleh Ashrafi, Julia Schlehe, Yao Liang Wong, Dennis Selkoe, Sarah Rice, Judith Steen, Matthew J LaVoie, Thomas L Schwarz. Cell 2011
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Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila.
Tom Cornelissen, Sven Vilain, Katlijn Vints, Natalia Gounko, Patrik Verstreken, Wim Vandenberghe. Elife 2018
Tom Cornelissen, Sven Vilain, Katlijn Vints, Natalia Gounko, Patrik Verstreken, Wim Vandenberghe. Elife 2018
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Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress.
Erin Quan Toyama, Sébastien Herzig, Julien Courchet, Tommy L Lewis, Oliver C Losón, Kristina Hellberg, Nathan P Young, Hsiuchen Chen, Franck Polleux, David C Chan,[...]. Science 2016
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Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins.
Vladimir V Rogov, Hironori Suzuki, Mija Marinković, Verena Lang, Ryuichi Kato, Masato Kawasaki, Maja Buljubašić, Matilda Šprung, Natalia Rogova, Soichi Wakatsuki,[...]. Sci Rep 2017
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The PINK1, synphilin-1 and SIAH-1 complex constitutes a novel mitophagy pathway.
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A regulatory signaling loop comprising the PGAM5 phosphatase and CK2 controls receptor-mediated mitophagy.
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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin.
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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.