A citation-based method for searching scientific literature

Anne Le, Charles R Cooper, Arvin M Gouw, Ramani Dinavahi, Anirban Maitra, Lorraine M Deck, Robert E Royer, David L Vander Jagt, Gregg L Semenza, Chi V Dang. Proc Natl Acad Sci U S A 2010
Times Cited: 872







List of co-cited articles
999 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
22


On the origin of cancer cells.
O WARBURG. Science 1956
20

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
16

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
15

Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.
Han Xie, Jun-Ichi Hanai, Jian-Guo Ren, Lev Kats, Kerri Burgess, Parul Bhargava, Sabina Signoretti, Julia Billiard, Kevin J Duffy, Aaron Grant,[...]. Cell Metab 2014
290
15

Targeting lactate metabolism for cancer therapeutics.
Joanne R Doherty, John L Cleveland. J Clin Invest 2013
594
14

THE METABOLISM OF TUMORS IN THE BODY.
O Warburg, F Wind, E Negelein. J Gen Physiol 1927
13

The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
12

Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition.
Aaron Boudreau, Hans E Purkey, Anna Hitz, Kirk Robarge, David Peterson, Sharada Labadie, Mandy Kwong, Rebecca Hong, Min Gao, Christopher Del Nagro,[...]. Nat Chem Biol 2016
107
12

Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells.
Julia Billiard, Jennifer B Dennison, Jacques Briand, Roland S Annan, Deping Chai, Mariela Colón, Christopher S Dodson, Seth A Gilbert, Joel Greshock, Junping Jing,[...]. Cancer Metab 2013
112
12

Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy.
Yangbo Feng, Yanlu Xiong, Tianyun Qiao, Xiaofei Li, Lintao Jia, Yong Han. Cancer Med 2018
150
12

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
11


LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Almut Brand, Katrin Singer, Gudrun E Koehl, Marlene Kolitzus, Gabriele Schoenhammer, Annette Thiel, Carina Matos, Christina Bruss, Sebastian Klobuch, Katrin Peter,[...]. Cell Metab 2016
611
11

Why do cancers have high aerobic glycolysis?
Robert A Gatenby, Robert J Gillies. Nat Rev Cancer 2004
11

Regulation of cancer cell metabolism.
Rob A Cairns, Isaac S Harris, Tak W Mak. Nat Rev Cancer 2011
10

Lactate Metabolism in Human Lung Tumors.
Brandon Faubert, Kevin Y Li, Ling Cai, Christopher T Hensley, Jiyeon Kim, Lauren G Zacharias, Chendong Yang, Quyen N Do, Sarah Doucette, Daniel Burguete,[...]. Cell 2017
537
10

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.
Pierre Sonveaux, Frédérique Végran, Thies Schroeder, Melanie C Wergin, Julien Verrax, Zahid N Rabbani, Christophe J De Saedeleer, Kelly M Kennedy, Caroline Diepart, Bénédicte F Jordan,[...]. J Clin Invest 2008
10

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells.
Anne Le, Andrew N Lane, Max Hamaker, Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilio J Rojas, Barbara S Slusher, Haixia Zhang,[...]. Cell Metab 2012
694
10

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
Oscar R Colegio, Ngoc-Quynh Chu, Alison L Szabo, Thach Chu, Anne Marie Rhebergen, Vikram Jairam, Nika Cyrus, Carolyn E Brokowski, Stephanie C Eisenbarth, Gillian M Phillips,[...]. Nature 2014
9

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
8

Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase.
Marcella Manerba, Marina Vettraino, Luigi Fiume, Giuseppina Di Stefano, Andrea Sartini, Elisa Giacomini, Rosa Buonfiglio, Marinella Roberti, Maurizio Recanatini. ChemMedChem 2012
93
8

Glucose feeds the TCA cycle via circulating lactate.
Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo,[...]. Nature 2017
576
8

The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor.
Cara J Valvona, Helen L Fillmore, Peter B Nunn, Geoffrey J Pilkington. Brain Pathol 2016
215
8

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH).
Ganesha Rai, Kyle R Brimacombe, Bryan T Mott, Daniel J Urban, Xin Hu, Shyh-Ming Yang, Tobie D Lee, Dorian M Cheff, Jennifer Kouznetsova, Gloria A Benavides,[...]. J Med Chem 2017
61
13

Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma.
Shi L Sheng, Jian J Liu, Yun H Dai, Xiao G Sun, Xiao P Xiong, Gang Huang. FEBS J 2012
155
8

Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis.
L Jin, J Chun, C Pan, G N Alesi, D Li, K R Magliocca, Y Kang, Z G Chen, D M Shin, F R Khuri,[...]. Oncogene 2017
103
8

Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors.
Prasanta Dutta, Anne Le, David L Vander Jagt, Takashi Tsukamoto, Gary V Martinez, Chi V Dang, Robert J Gillies. Cancer Res 2013
54
14


MYC-induced cancer cell energy metabolism and therapeutic opportunities.
Chi V Dang, Anne Le, Ping Gao. Clin Cancer Res 2009
578
7

Tumor-derived lactic acid modulates dendritic cell activation and antigen expression.
Eva Gottfried, Leoni A Kunz-Schughart, Stephanie Ebner, Wolfgang Mueller-Klieser, Sabine Hoves, Reinhard Andreesen, Andreas Mackensen, Marina Kreutz. Blood 2006
368
7

Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.
Carlotta Granchi, Sarabindu Roy, Chiara Giacomelli, Marco Macchia, Tiziano Tuccinardi, Adriano Martinelli, Mario Lanza, Laura Betti, Gino Giannaccini, Antonio Lucacchini,[...]. J Med Chem 2011
133
7

Metabolic regulation of gene expression by histone lactylation.
Di Zhang, Zhanyun Tang, He Huang, Guolin Zhou, Chang Cui, Yejing Weng, Wenchao Liu, Sunjoo Kim, Sangkyu Lee, Mathew Perez-Neut,[...]. Nature 2019
448
7

Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
7

Cooperation and competition in the evolution of ATP-producing pathways.
T Pfeiffer, S Schuster, S Bonhoeffer. Science 2001
761
7

Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol.
Ming Zhou, Yuhua Zhao, Yan Ding, Hao Liu, Zixing Liu, Oystein Fodstad, Adam I Riker, Sushama Kamarajugadda, Jianrong Lu, Laurie B Owen,[...]. Mol Cancer 2010
247
7


Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Matt I Gross, Susan D Demo, Jennifer B Dennison, Lijing Chen, Tania Chernov-Rogan, Bindu Goyal, Julie R Janes, Guy J Laidig, Evan R Lewis, Jim Li,[...]. Mol Cancer Ther 2014
541
7

Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.
Maša Ždralević, Almut Brand, Lorenza Di Ianni, Katja Dettmer, Jörg Reinders, Katrin Singer, Katrin Peter, Annette Schnell, Christina Bruss, Sonja-Maria Decking,[...]. J Biol Chem 2018
90
7

Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis.
Frédérique Végran, Romain Boidot, Carine Michiels, Pierre Sonveaux, Olivier Feron. Cancer Res 2011
460
6

Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions.
Robert Haas, Joanne Smith, Vidalba Rocher-Ros, Suchita Nadkarni, Trinidad Montero-Melendez, Fulvio D'Acquisto, Elliot J Bland, Michele Bombardieri, Costantino Pitzalis, Mauro Perretti,[...]. PLoS Biol 2015
303
6

Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia.
M Maftouh, A Avan, R Sciarrillo, C Granchi, L G Leon, R Rani, N Funel, K Smid, R Honeywell, U Boggi,[...]. Br J Cancer 2014
97
6

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.
Yan Xiang, Zachary E Stine, Jinsong Xia, Yunqi Lu, Roddy S O'Connor, Brian J Altman, Annie L Hsieh, Arvin M Gouw, Ajit G Thomas, Ping Gao,[...]. J Clin Invest 2015
237
6

c-Myc transactivation of LDH-A: implications for tumor metabolism and growth.
H Shim, C Dolde, B C Lewis, C S Wu, G Dang, R A Jungmann, R Dalla-Favera, C V Dang. Proc Natl Acad Sci U S A 1997
766
6

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Andrea Viale, Piergiorgio Pettazzoni, Costas A Lyssiotis, Haoqiang Ying, Nora Sánchez, Matteo Marchesini, Alessandro Carugo, Tessa Green, Sahil Seth, Virginia Giuliani,[...]. Nature 2014
718
6

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis.
William W Wheaton, Samuel E Weinberg, Robert B Hamanaka, Saul Soberanes, Lucas B Sullivan, Elena Anso, Andrea Glasauer, Eric Dufour, Gokhan M Mutlu, Gr Scott Budigner,[...]. Elife 2014
620
6

Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase.
J A Read, V J Winter, C M Eszes, R B Sessions, R L Brady. Proteins 2001
159
6

Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials.
C Granchi, S Bertini, M Macchia, F Minutolo. Curr Med Chem 2010
115
6

Inhibition of LDHA suppresses tumor progression in prostate cancer.
Zhi-Yong Xian, Jiu-Min Liu, Qing-Ke Chen, Han-Zhong Chen, Chu-Jin Ye, Jian Xue, Huan-Qing Yang, Jing-Lei Li, Xue-Feng Liu, Su-Juan Kuang. Tumour Biol 2015
78
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.