A citation-based method for searching scientific literature

Kaspar Burger, Bastian Mühl, Thomas Harasim, Michaela Rohrmoser, Anastassia Malamoussi, Mathias Orban, Markus Kellner, Anita Gruber-Eber, Elisabeth Kremmer, Michael Hölzel, Dirk Eick. J Biol Chem 2010
Times Cited: 262







List of co-cited articles
1061 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.
Denis Drygin, Amy Lin, Josh Bliesath, Caroline B Ho, Sean E O'Brien, Chris Proffitt, Mayuko Omori, Mustapha Haddach, Michael K Schwaebe, Adam Siddiqui-Jain,[...]. Cancer Res 2011
341
38

Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Megan J Bywater, Gretchen Poortinga, Elaine Sanij, Nadine Hein, Abigail Peck, Carleen Cullinane, Meaghan Wall, Leonie Cluse, Denis Drygin, Kenna Anderes,[...]. Cancer Cell 2012
365
33

The nucleolus under stress.
Séverine Boulon, Belinda J Westman, Saskia Hutten, François-Michel Boisvert, Angus I Lamond. Mol Cell 2010
629
30

A targeting modality for destruction of RNA polymerase I that possesses anticancer activity.
Karita Peltonen, Laureen Colis, Hester Liu, Rishi Trivedi, Michael S Moubarek, Henna M Moore, Baoyan Bai, Michelle A Rudek, Charles J Bieberich, Marikki Laiho. Cancer Cell 2014
157
26

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress.
Peter M Bruno, Yunpeng Liu, Ga Young Park, Junko Murai, Catherine E Koch, Timothy J Eisen, Justin R Pritchard, Yves Pommier, Stephen J Lippard, Michael T Hemann. Nat Med 2017
204
24

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.
Hong Xu, Marco Di Antonio, Steven McKinney, Veena Mathew, Brandon Ho, Nigel J O'Neil, Nancy Dos Santos, Jennifer Silvester, Vivien Wei, Jessica Garcia,[...]. Nat Commun 2017
236
23


The multifunctional nucleolus.
François-Michel Boisvert, Silvana van Koningsbruggen, Joaquín Navascués, Angus I Lamond. Nat Rev Mol Cell Biol 2007
20

Ribosome biogenesis in cancer: new players and therapeutic avenues.
Joffrey Pelletier, George Thomas, Siniša Volarević. Nat Rev Cancer 2018
273
20

The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer.
Denis Drygin, William G Rice, Ingrid Grummt. Annu Rev Pharmacol Toxicol 2010
290
18

Targeting the nucleolus for cancer intervention.
Jaclyn E Quin, Jennifer R Devlin, Donald Cameron, Kate M Hannan, Richard B Pearson, Ross D Hannan. Biochim Biophys Acta 2014
151
18

MYC as a regulator of ribosome biogenesis and protein synthesis.
Jan van Riggelen, Alper Yetil, Dean W Felsher. Nat Rev Cancer 2010
537
18

p53 and ribosome biogenesis stress: the essentials.
Lior Golomb, Sinisa Volarevic, Moshe Oren. FEBS Lett 2014
144
16


Identification of novel p53 pathway activating small-molecule compounds reveals unexpected similarities with known therapeutic agents.
Karita Peltonen, Laureen Colis, Hester Liu, Sari Jäämaa, Henna M Moore, Juulia Enbäck, Pirjo Laakkonen, Anne Vaahtokari, Richard J Jones, Taija M af Hällström,[...]. PLoS One 2010
65
24

Anticancer activity of CX-3543: a direct inhibitor of rRNA biogenesis.
Denis Drygin, Adam Siddiqui-Jain, Sean O'Brien, Michael Schwaebe, Amy Lin, Josh Bliesath, Caroline B Ho, Chris Proffitt, Katy Trent, Jeffrey P Whitten,[...]. Cancer Res 2009
348
16

What the nucleolus says to a tumour pathologist.
Massimo Derenzini, Lorenzo Montanaro, Davide Treré. Histopathology 2009
157
15

The nucleolus: an emerging target for cancer therapy.
Nadine Hein, Katherine M Hannan, Amee J George, Elaine Sanij, Ross D Hannan. Trends Mol Med 2013
145
15

Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition.
Yaron Shav-Tal, Janna Blechman, Xavier Darzacq, Cristina Montagna, Billy T Dye, James G Patton, Robert H Singer, Dov Zipori. Mol Biol Cell 2005
241
14

Does the ribosome translate cancer?
Davide Ruggero, Pier Paolo Pandolfi. Nat Rev Cancer 2003
723
14

Ribosome biogenesis: An emerging druggable pathway for cancer therapeutics.
Frédéric Catez, Nicole Dalla Venezia, Virginie Marcel, Christiane Zorbas, Denis L J Lafontaine, Jean-Jacques Diaz. Biochem Pharmacol 2019
61
22

Nucleolar stress with and without p53.
Allison James, Yubo Wang, Himanshu Raje, Raphyel Rosby, Patrick DiMario. Nucleus 2014
163
13

Signaling to p53: ribosomal proteins find their way.
Yanping Zhang, Hua Lu. Cancer Cell 2009
409
13

Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis.
Mikael S Lindström, Deana Jurada, Sladana Bursac, Ines Orsolic, Jiri Bartek, Sinisa Volarevic. Oncogene 2018
96
13

Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress.
Emilien Nicolas, Pascaline Parisot, Celina Pinto-Monteiro, Roxane de Walque, Christophe De Vleeschouwer, Denis L J Lafontaine. Nat Commun 2016
96
12

Coexisting Liquid Phases Underlie Nucleolar Subcompartments.
Marina Feric, Nilesh Vaidya, Tyler S Harmon, Diana M Mitrea, Lian Zhu, Tiffany M Richardson, Richard W Kriwacki, Rohit V Pappu, Clifford P Brangwynne. Cell 2016
763
12

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study.
Amit Khot, Natalie Brajanovski, Donald P Cameron, Nadine Hein, Kylee H Maclachlan, Elaine Sanij, John Lim, John Soong, Emma Link, Piers Blombery,[...]. Cancer Discov 2019
65
18

Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age.
Rita Ferreira, John S Schneekloth, Konstantin I Panov, Katherine M Hannan, Ross D Hannan. Cells 2020
50
24

Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress.
Sladana Bursać, Maja Cokarić Brdovčak, Martin Pfannkuchen, Ines Orsolić, Lior Golomb, Yan Zhu, Chen Katz, Lilyn Daftuar, Kristina Grabušić, Iva Vukelić,[...]. Proc Natl Acad Sci U S A 2012
133
11

Activation of the tumor suppressor p53 upon impairment of ribosome biogenesis.
Sladana Bursac, Maja Cokaric Brdovcak, Giulio Donati, Sinisa Volarevic. Biochim Biophys Acta 2014
100
11

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.
Azadeh Arabi, Siqin Wu, Karin Ridderstråle, Holger Bierhoff, Chiounan Shiue, Karoly Fatyol, Sara Fahlén, Per Hydbring, Ola Söderberg, Ingrid Grummt,[...]. Nat Cell Biol 2005
337
11

The economics of ribosome biosynthesis in yeast.
J R Warner. Trends Biochem Sci 1999
11

Discovery of CX-5461, the First Direct and Selective Inhibitor of RNA Polymerase I, for Cancer Therapeutics.
Mustapha Haddach, Michael K Schwaebe, Jerome Michaux, Johnny Nagasawa, Sean E O'Brien, Jeffrey P Whitten, Fabrice Pierre, Pauline Kerdoncuff, Levan Darjania, Ryan Stansfield,[...]. ACS Med Chem Lett 2012
70
15

Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint.
Ting Wei, Saman M Najmi, Hester Liu, Karita Peltonen, Alena Kucerova, David A Schneider, Marikki Laiho. Cell Rep 2018
32
34

The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress.
Katherine E Sloan, Markus T Bohnsack, Nicholas J Watkins. Cell Rep 2013
172
10


Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction.
Stefano Fumagalli, Alessandro Di Cara, Arti Neb-Gulati, Francois Natt, Sandy Schwemberger, Jonathan Hall, George F Babcock, Rosa Bernardi, Pier Paolo Pandolfi, George Thomas. Nat Cell Biol 2009
242
10

p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer.
Virginie Marcel, Sandra E Ghayad, Stéphane Belin, Gabriel Therizols, Anne-Pierre Morel, Eduardo Solano-Gonzàlez, Julie A Vendrell, Sabine Hacot, Hichem C Mertani, Marie Alexandra Albaret,[...]. Cancer Cell 2013
171
10

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population.
Nadine Hein, Donald P Cameron, Katherine M Hannan, Nhu-Y N Nguyen, Chun Yew Fong, Jirawas Sornkom, Meaghan Wall, Megan Pavy, Carleen Cullinane, Jeannine Diesch,[...]. Blood 2017
41
24

Targeted cancer therapy with ribosome biogenesis inhibitors: a real possibility?
Elisa Brighenti, Davide Treré, Massimo Derenzini. Oncotarget 2015
49
20

The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy.
Simone J Woods, Katherine M Hannan, Richard B Pearson, Ross D Hannan. Biochim Biophys Acta 2015
91
10

Nucleolar reorganization in response to rDNA damage.
Marjolein van Sluis, Brian McStay. Curr Opin Cell Biol 2017
47
21

Nucleolus, ribosomes, and cancer.
Lorenzo Montanaro, Davide Treré, Massimo Derenzini. Am J Pathol 2008
298
10

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling.
Jaclyn Quin, Keefe T Chan, Jennifer R Devlin, Donald P Cameron, Jeannine Diesch, Carleen Cullinane, Jessica Ahern, Amit Khot, Nadine Hein, Amee J George,[...]. Oncotarget 2016
60
16

ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage Recognition.
Shane M Harding, Jonathan A Boiarsky, Roger A Greenberg. Cell Rep 2015
99
9

The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks.
Michael Kruhlak, Elizabeth E Crouch, Marika Orlov, Carolina Montaño, Stanislaw A Gorski, André Nussenzweig, Tom Misteli, Robert D Phair, Rafael Casellas. Nature 2007
207
9

Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency.
Maria Barna, Aya Pusic, Ornella Zollo, Maria Costa, Nadya Kondrashov, Eduardo Rego, Pulivarthi H Rao, Davide Ruggero. Nature 2008
291
9

Ribosomopathies: human disorders of ribosome dysfunction.
Anupama Narla, Benjamin L Ebert. Blood 2010
508
9

Ribosome biogenesis and cancer.
Massimo Derenzini, Lorenzo Montanaro, Davide Trerè. Acta Histochem 2017
67
13



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.