Simona Negrini, Vassilis G Gorgoulis, Thanos D Halazonetis. Nat Rev Mol Cell Biol 2010
Times Cited: 1267
Times Cited: 1267
Times Cited
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27
An oncogene-induced DNA damage model for cancer development.
Thanos D Halazonetis, Vassilis G Gorgoulis, Jiri Bartek. Science 2008
Thanos D Halazonetis, Vassilis G Gorgoulis, Jiri Bartek. Science 2008
9
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
9
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
Jirina Bartkova, Zuzana Horejsí, Karen Koed, Alwin Krämer, Frederic Tort, Karsten Zieger, Per Guldberg, Maxwell Sehested, Jahn M Nesland, Claudia Lukas,[...]. Nature 2005
Jirina Bartkova, Zuzana Horejsí, Karen Koed, Alwin Krämer, Frederic Tort, Karsten Zieger, Per Guldberg, Maxwell Sehested, Jahn M Nesland, Claudia Lukas,[...]. Nature 2005
9
Endogenous DNA Damage as a Source of Genomic Instability in Cancer.
Anthony Tubbs, André Nussenzweig. Cell 2017
Anthony Tubbs, André Nussenzweig. Cell 2017
8
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.
Vassilis G Gorgoulis, Leandros-Vassilios F Vassiliou, Panagiotis Karakaidos, Panayotis Zacharatos, Athanassios Kotsinas, Triantafillos Liloglou, Monica Venere, Richard A Ditullio, Nikolaos G Kastrinakis, Brynn Levy,[...]. Nature 2005
Vassilis G Gorgoulis, Leandros-Vassilios F Vassiliou, Panagiotis Karakaidos, Panayotis Zacharatos, Athanassios Kotsinas, Triantafillos Liloglou, Monica Venere, Richard A Ditullio, Nikolaos G Kastrinakis, Brynn Levy,[...]. Nature 2005
7
DNA repair, genome stability and cancer: a historical perspective.
Penny A Jeggo, Laurence H Pearl, Antony M Carr. Nat Rev Cancer 2016
Penny A Jeggo, Laurence H Pearl, Antony M Carr. Nat Rev Cancer 2016
7
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
7
Mitotic progression following DNA damage enables pattern recognition within micronuclei.
Shane M Harding, Joseph L Benci, Jerome Irianto, Dennis E Discher, Andy J Minn, Roger A Greenberg. Nature 2017
Shane M Harding, Joseph L Benci, Jerome Irianto, Dennis E Discher, Andy J Minn, Roger A Greenberg. Nature 2017
6
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson, Tobias B Richardson, Manuela Santarosa, Krystyna J Dillon, Ian Hickson, Charlotte Knights,[...]. Nature 2005
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson, Tobias B Richardson, Manuela Santarosa, Krystyna J Dillon, Ian Hickson, Charlotte Knights,[...]. Nature 2005
6
Cancer statistics, 2020.
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2020
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2020
6
The DNA-damage response in human biology and disease.
Stephen P Jackson, Jiri Bartek. Nature 2009
Stephen P Jackson, Jiri Bartek. Nature 2009
6
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.
Mathias Munschauer, Celina T Nguyen, Klara Sirokman, Christina R Hartigan, Larson Hogstrom, Jesse M Engreitz, Jacob C Ulirsch, Charles P Fulco, Vidya Subramanian, Jenny Chen,[...]. Nature 2018
Mathias Munschauer, Celina T Nguyen, Klara Sirokman, Christina R Hartigan, Larson Hogstrom, Jesse M Engreitz, Jacob C Ulirsch, Charles P Fulco, Vidya Subramanian, Jenny Chen,[...]. Nature 2018
6
The DNA damage response: making it safe to play with knives.
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
5
State-of-the-art strategies for targeting the DNA damage response in cancer.
Patrick G Pilié, Chad Tang, Gordon B Mills, Timothy A Yap. Nat Rev Clin Oncol 2019
Patrick G Pilié, Chad Tang, Gordon B Mills, Timothy A Yap. Nat Rev Clin Oncol 2019
5
Genomic and Functional Approaches to Understanding Cancer Aneuploidy.
Alison M Taylor, Juliann Shih, Gavin Ha, Galen F Gao, Xiaoyang Zhang, Ashton C Berger, Steven E Schumacher, Chen Wang, Hai Hu, Jianfang Liu,[...]. Cancer Cell 2018
Alison M Taylor, Juliann Shih, Gavin Ha, Galen F Gao, Xiaoyang Zhang, Ashton C Berger, Steven E Schumacher, Chen Wang, Hai Hu, Jianfang Liu,[...]. Cancer Cell 2018
5
Pan-cancer patterns of somatic copy number alteration.
Travis I Zack, Stephen E Schumacher, Scott L Carter, Andre D Cherniack, Gordon Saksena, Barbara Tabak, Michael S Lawrence, Cheng-Zhong Zhsng, Jeremiah Wala, Craig H Mermel,[...]. Nat Genet 2013
Travis I Zack, Stephen E Schumacher, Scott L Carter, Andre D Cherniack, Gordon Saksena, Barbara Tabak, Michael S Lawrence, Cheng-Zhong Zhsng, Jeremiah Wala, Craig H Mermel,[...]. Nat Genet 2013
5
cGAS surveillance of micronuclei links genome instability to innate immunity.
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
5
DNA breaks and chromosome pulverization from errors in mitosis.
Karen Crasta, Neil J Ganem, Regina Dagher, Alexandra B Lantermann, Elena V Ivanova, Yunfeng Pan, Luigi Nezi, Alexei Protopopov, Dipanjan Chowdhury, David Pellman. Nature 2012
Karen Crasta, Neil J Ganem, Regina Dagher, Alexandra B Lantermann, Elena V Ivanova, Yunfeng Pan, Luigi Nezi, Alexei Protopopov, Dipanjan Chowdhury, David Pellman. Nature 2012
5
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.
Raphael Ceccaldi, Jessica C Liu, Ravindra Amunugama, Ildiko Hajdu, Benjamin Primack, Mark I R Petalcorin, Kevin W O'Connor, Panagiotis A Konstantinopoulos, Stephen J Elledge, Simon J Boulton,[...]. Nature 2015
Raphael Ceccaldi, Jessica C Liu, Ravindra Amunugama, Ildiko Hajdu, Benjamin Primack, Mark I R Petalcorin, Kevin W O'Connor, Panagiotis A Konstantinopoulos, Stephen J Elledge, Simon J Boulton,[...]. Nature 2015
5
Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.
Katharina Schlacher, Nicole Christ, Nicolas Siaud, Akinori Egashira, Hong Wu, Maria Jasin. Cell 2011
Katharina Schlacher, Nicole Christ, Nicolas Siaud, Akinori Egashira, Hong Wu, Maria Jasin. Cell 2011
5
Genomic Instability in Cancer: Teetering on the Limit of Tolerance.
Noemi Andor, Carlo C Maley, Hanlee P Ji. Cancer Res 2017
Noemi Andor, Carlo C Maley, Hanlee P Ji. Cancer Res 2017
5
Computational identification of mutator-derived lncRNA signatures of genome instability for improving the clinical outcome of cancers: a case study in breast cancer.
Siqi Bao, Hengqiang Zhao, Jian Yuan, Dandan Fan, Zicheng Zhang, Jianzhong Su, Meng Zhou. Brief Bioinform 2020
Siqi Bao, Hengqiang Zhao, Jian Yuan, Dandan Fan, Zicheng Zhang, Jianzhong Su, Meng Zhou. Brief Bioinform 2020
7
Mechanisms of DNA damage, repair, and mutagenesis.
Nimrat Chatterjee, Graham C Walker. Environ Mol Mutagen 2017
Nimrat Chatterjee, Graham C Walker. Environ Mol Mutagen 2017
5
Causes and consequences of replication stress.
Michelle K Zeman, Karlene A Cimprich. Nat Cell Biol 2014
Michelle K Zeman, Karlene A Cimprich. Nat Cell Biol 2014
5
Inferring tumour purity and stromal and immune cell admixture from expression data.
Kosuke Yoshihara, Maria Shahmoradgoli, Emmanuel Martínez, Rahulsimham Vegesna, Hoon Kim, Wandaliz Torres-Garcia, Victor Treviño, Hui Shen, Peter W Laird, Douglas A Levine,[...]. Nat Commun 2013
Kosuke Yoshihara, Maria Shahmoradgoli, Emmanuel Martínez, Rahulsimham Vegesna, Hoon Kim, Wandaliz Torres-Garcia, Victor Treviño, Hui Shen, Peter W Laird, Douglas A Levine,[...]. Nat Commun 2013
5
DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
5
Olaparib for Metastatic Castration-Resistant Prostate Cancer.
Johann de Bono, Joaquin Mateo, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, Kim N Chi, Oliver Sartor, Neeraj Agarwal, David Olmos,[...]. N Engl J Med 2020
Johann de Bono, Joaquin Mateo, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, Kim N Chi, Oliver Sartor, Neeraj Agarwal, David Olmos,[...]. N Engl J Med 2020
4
Mechanisms of Genomic Instability in Breast Cancer.
Pascal H G Duijf, Devathri Nanayakkara, Katia Nones, Sriganesh Srihari, Murugan Kalimutho, Kum Kum Khanna. Trends Mol Med 2019
Pascal H G Duijf, Devathri Nanayakkara, Katia Nones, Sriganesh Srihari, Murugan Kalimutho, Kum Kum Khanna. Trends Mol Med 2019
9
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Cristina Escribano-Díaz, Alexandre Orthwein, Amélie Fradet-Turcotte, Mengtan Xing, Jordan T F Young, Ján Tkáč, Michael A Cook, Adam P Rosebrock, Meagan Munro, Marella D Canny,[...]. Mol Cell 2013
Cristina Escribano-Díaz, Alexandre Orthwein, Amélie Fradet-Turcotte, Mengtan Xing, Jordan T F Young, Ján Tkáč, Michael A Cook, Adam P Rosebrock, Meagan Munro, Marella D Canny,[...]. Mol Cell 2013
4
The causes and consequences of genetic heterogeneity in cancer evolution.
Rebecca A Burrell, Nicholas McGranahan, Jiri Bartek, Charles Swanton. Nature 2013
Rebecca A Burrell, Nicholas McGranahan, Jiri Bartek, Charles Swanton. Nature 2013
4
DNA damage sensing by the ATM and ATR kinases.
Alexandre Maréchal, Lee Zou. Cold Spring Harb Perspect Biol 2013
Alexandre Maréchal, Lee Zou. Cold Spring Harb Perspect Biol 2013
4
Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy.
Teresa Davoli, Hajime Uno, Eric C Wooten, Stephen J Elledge. Science 2017
Teresa Davoli, Hajime Uno, Eric C Wooten, Stephen J Elledge. Science 2017
4
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.
Theo A Knijnenburg, Linghua Wang, Michael T Zimmermann, Nyasha Chambwe, Galen F Gao, Andrew D Cherniack, Huihui Fan, Hui Shen, Gregory P Way, Casey S Greene,[...]. Cell Rep 2018
Theo A Knijnenburg, Linghua Wang, Michael T Zimmermann, Nyasha Chambwe, Galen F Gao, Andrew D Cherniack, Huihui Fan, Hui Shen, Gregory P Way, Casey S Greene,[...]. Cell Rep 2018
4
A role for human homologous recombination factors in suppressing microhomology-mediated end joining.
Sara Ahrabi, Sovan Sarkar, Sophia X Pfister, Giacomo Pirovano, Geoff S Higgins, Andrew C G Porter, Timothy C Humphrey. Nucleic Acids Res 2016
Sara Ahrabi, Sovan Sarkar, Sophia X Pfister, Giacomo Pirovano, Geoff S Higgins, Andrew C G Porter, Timothy C Humphrey. Nucleic Acids Res 2016
7
Catastrophic nuclear envelope collapse in cancer cell micronuclei.
Emily M Hatch, Andrew H Fischer, Thomas J Deerinck, Martin W Hetzer. Cell 2013
Emily M Hatch, Andrew H Fischer, Thomas J Deerinck, Martin W Hetzer. Cell 2013
4
Cancer genome landscapes.
Bert Vogelstein, Nickolas Papadopoulos, Victor E Velculescu, Shibin Zhou, Luis A Diaz, Kenneth W Kinzler. Science 2013
Bert Vogelstein, Nickolas Papadopoulos, Victor E Velculescu, Shibin Zhou, Luis A Diaz, Kenneth W Kinzler. Science 2013
4
Chromothripsis from DNA damage in micronuclei.
Cheng-Zhong Zhang, Alexander Spektor, Hauke Cornils, Joshua M Francis, Emily K Jackson, Shiwei Liu, Matthew Meyerson, David Pellman. Nature 2015
Cheng-Zhong Zhang, Alexander Spektor, Hauke Cornils, Joshua M Francis, Emily K Jackson, Shiwei Liu, Matthew Meyerson, David Pellman. Nature 2015
4
The Multifaceted Role of Chromosomal Instability in Cancer and Its Microenvironment.
Samuel F Bakhoum, Lewis C Cantley. Cell 2018
Samuel F Bakhoum, Lewis C Cantley. Cell 2018
4
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
4
Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.
Lynnette R Ferguson, Helen Chen, Andrew R Collins, Marisa Connell, Giovanna Damia, Santanu Dasgupta, Meenakshi Malhotra, Alan K Meeker, Amedeo Amedei, Amr Amin,[...]. Semin Cancer Biol 2015
Lynnette R Ferguson, Helen Chen, Andrew R Collins, Marisa Connell, Giovanna Damia, Santanu Dasgupta, Meenakshi Malhotra, Alan K Meeker, Amedeo Amedei, Amr Amin,[...]. Semin Cancer Biol 2015
4
Cell cycle regulation by checkpoints.
Kevin J Barnum, Matthew J O'Connell. Methods Mol Biol 2014
Kevin J Barnum, Matthew J O'Connell. Methods Mol Biol 2014
4
The essential kinase ATR: ensuring faithful duplication of a challenging genome.
Joshua C Saldivar, David Cortez, Karlene A Cimprich. Nat Rev Mol Cell Biol 2017
Joshua C Saldivar, David Cortez, Karlene A Cimprich. Nat Rev Mol Cell Biol 2017
4
BGL3 lncRNA mediates retention of the BRCA1/BARD1 complex at DNA damage sites.
Zhaohua Hu, Shaojie Mi, Ting Zhao, Changmin Peng, Yihan Peng, Lulu Chen, Wenge Zhu, Yi Yao, Qibin Song, Xiangpan Li,[...]. EMBO J 2020
Zhaohua Hu, Shaojie Mi, Ting Zhao, Changmin Peng, Yihan Peng, Lulu Chen, Wenge Zhu, Yi Yao, Qibin Song, Xiangpan Li,[...]. EMBO J 2020
17
Replication stress links structural and numerical cancer chromosomal instability.
Rebecca A Burrell, Sarah E McClelland, David Endesfelder, Petra Groth, Marie-Christine Weller, Nadeem Shaikh, Enric Domingo, Nnennaya Kanu, Sally M Dewhurst, Eva Gronroos,[...]. Nature 2013
Rebecca A Burrell, Sarah E McClelland, David Endesfelder, Petra Groth, Marie-Christine Weller, Nadeem Shaikh, Enric Domingo, Nnennaya Kanu, Sally M Dewhurst, Eva Gronroos,[...]. Nature 2013
3
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