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Times Cited: 1498
Times Cited: 1498
Times Cited
Times Co-cited
Similarity
Chimeric antigen receptor T cells for sustained remissions in leukemia.
Shannon L Maude, Noelle Frey, Pamela A Shaw, Richard Aplenc, David M Barrett, Nancy J Bunin, Anne Chew, Vanessa E Gonzalez, Zhaohui Zheng, Simon F Lacey,[...]. N Engl J Med 2014
Shannon L Maude, Noelle Frey, Pamela A Shaw, Richard Aplenc, David M Barrett, Nancy J Bunin, Anne Chew, Vanessa E Gonzalez, Zhaohui Zheng, Simon F Lacey,[...]. N Engl J Med 2014
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Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia.
Shannon L Maude, Theodore W Laetsch, Jochen Buechner, Susana Rives, Michael Boyer, Henrique Bittencourt, Peter Bader, Michael R Verneris, Heather E Stefanski, Gary D Myers,[...]. N Engl J Med 2018
Shannon L Maude, Theodore W Laetsch, Jochen Buechner, Susana Rives, Michael Boyer, Henrique Bittencourt, Peter Bader, Michael R Verneris, Heather E Stefanski, Gary D Myers,[...]. N Engl J Med 2018
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Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma.
Sattva S Neelapu, Frederick L Locke, Nancy L Bartlett, Lazaros J Lekakis, David B Miklos, Caron A Jacobson, Ira Braunschweig, Olalekan O Oluwole, Tanya Siddiqi, Yi Lin,[...]. N Engl J Med 2017
Sattva S Neelapu, Frederick L Locke, Nancy L Bartlett, Lazaros J Lekakis, David B Miklos, Caron A Jacobson, Ira Braunschweig, Olalekan O Oluwole, Tanya Siddiqi, Yi Lin,[...]. N Engl J Med 2017
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Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia.
Jae H Park, Isabelle Rivière, Mithat Gonen, Xiuyan Wang, Brigitte Sénéchal, Kevin J Curran, Craig Sauter, Yongzeng Wang, Bianca Santomasso, Elena Mead,[...]. N Engl J Med 2018
Jae H Park, Isabelle Rivière, Mithat Gonen, Xiuyan Wang, Brigitte Sénéchal, Kevin J Curran, Craig Sauter, Yongzeng Wang, Bianca Santomasso, Elena Mead,[...]. N Engl J Med 2018
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A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.
Donald M O'Rourke, MacLean P Nasrallah, Arati Desai, Jan J Melenhorst, Keith Mansfield, Jennifer J D Morrissette, Maria Martinez-Lage, Steven Brem, Eileen Maloney, Angela Shen,[...]. Sci Transl Med 2017
Donald M O'Rourke, MacLean P Nasrallah, Arati Desai, Jan J Melenhorst, Keith Mansfield, Jennifer J D Morrissette, Maria Martinez-Lage, Steven Brem, Eileen Maloney, Angela Shen,[...]. Sci Transl Med 2017
22
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors.
Adrienne H Long, Waleed M Haso, Jack F Shern, Kelsey M Wanhainen, Meera Murgai, Maria Ingaramo, Jillian P Smith, Alec J Walker, M Eric Kohler, Vikas R Venkateshwara,[...]. Nat Med 2015
Adrienne H Long, Waleed M Haso, Jack F Shern, Kelsey M Wanhainen, Meera Murgai, Maria Ingaramo, Jillian P Smith, Alec J Walker, M Eric Kohler, Vikas R Venkateshwara,[...]. Nat Med 2015
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Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy.
Christine E Brown, Darya Alizadeh, Renate Starr, Lihong Weng, Jamie R Wagner, Araceli Naranjo, Julie R Ostberg, M Suzette Blanchard, Julie Kilpatrick, Jennifer Simpson,[...]. N Engl J Med 2016
Christine E Brown, Darya Alizadeh, Renate Starr, Lihong Weng, Jamie R Wagner, Araceli Naranjo, Julie R Ostberg, M Suzette Blanchard, Julie Kilpatrick, Jennifer Simpson,[...]. N Engl J Med 2016
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Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells.
Christopher C Kloss, Maud Condomines, Marc Cartellieri, Michael Bachmann, Michel Sadelain. Nat Biotechnol 2013
Christopher C Kloss, Maud Condomines, Marc Cartellieri, Michael Bachmann, Michel Sadelain. Nat Biotechnol 2013
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Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor.
Edmund K Moon, Carmine Carpenito, Jing Sun, Liang-Chuan S Wang, Veena Kapoor, Jarrod Predina, Daniel J Powell, James L Riley, Carl H June, Steven M Albelda. Clin Cancer Res 2011
Edmund K Moon, Carmine Carpenito, Jing Sun, Liang-Chuan S Wang, Veena Kapoor, Jarrod Predina, Daniel J Powell, James L Riley, Carl H June, Steven M Albelda. Clin Cancer Res 2011
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CAR T Cell Therapy for Solid Tumors.
Kheng Newick, Shaun O'Brien, Edmund Moon, Steven M Albelda. Annu Rev Med 2017
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The basic principles of chimeric antigen receptor design.
Michel Sadelain, Renier Brentjens, Isabelle Rivière. Cancer Discov 2013
Michel Sadelain, Renier Brentjens, Isabelle Rivière. Cancer Discov 2013
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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia.
Stephan A Grupp, Michael Kalos, David Barrett, Richard Aplenc, David L Porter, Susan R Rheingold, David T Teachey, Anne Chew, Bernd Hauck, J Fraser Wright,[...]. N Engl J Med 2013
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Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes.
Ignazio Caruana, Barbara Savoldo, Valentina Hoyos, Gerrit Weber, Hao Liu, Eugene S Kim, Michael M Ittmann, Dario Marchetti, Gianpietro Dotti. Nat Med 2015
Ignazio Caruana, Barbara Savoldo, Valentina Hoyos, Gerrit Weber, Hao Liu, Eugene S Kim, Michael M Ittmann, Dario Marchetti, Gianpietro Dotti. Nat Med 2015
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IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors in vivo.
Mythili Koneru, Terence J Purdon, David Spriggs, Susmith Koneru, Renier J Brentjens. Oncoimmunology 2015
Mythili Koneru, Terence J Purdon, David Spriggs, Susmith Koneru, Renier J Brentjens. Oncoimmunology 2015
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Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits.
Kole T Roybal, Levi J Rupp, Leonardo Morsut, Whitney J Walker, Krista A McNally, Jason S Park, Wendell A Lim. Cell 2016
Kole T Roybal, Levi J Rupp, Leonardo Morsut, Whitney J Walker, Krista A McNally, Jason S Park, Wendell A Lim. Cell 2016
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IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor.
Keishi Adachi, Yosuke Kano, Tomohiko Nagai, Namiko Okuyama, Yukimi Sakoda, Koji Tamada. Nat Biotechnol 2018
Keishi Adachi, Yosuke Kano, Tomohiko Nagai, Namiko Okuyama, Yukimi Sakoda, Koji Tamada. Nat Biotechnol 2018
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Chimeric antigen receptor T-cell therapy - assessment and management of toxicities.
Sattva S Neelapu, Sudhakar Tummala, Partow Kebriaei, William Wierda, Cristina Gutierrez, Frederick L Locke, Krishna V Komanduri, Yi Lin, Nitin Jain, Naval Daver,[...]. Nat Rev Clin Oncol 2018
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T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial.
Daniel W Lee, James N Kochenderfer, Maryalice Stetler-Stevenson, Yongzhi K Cui, Cindy Delbrook, Steven A Feldman, Terry J Fry, Rimas Orentas, Marianna Sabatino, Nirali N Shah,[...]. Lancet 2015
Daniel W Lee, James N Kochenderfer, Maryalice Stetler-Stevenson, Yongzhi K Cui, Cindy Delbrook, Steven A Feldman, Terry J Fry, Rimas Orentas, Marianna Sabatino, Nirali N Shah,[...]. Lancet 2015
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T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.
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Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses.
Jang Hwan Cho, James J Collins, Wilson W Wong. Cell 2018
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PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses.
Victor D Fedorov, Maria Themeli, Michel Sadelain. Sci Transl Med 2013
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Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo.
Sarwish Rafiq, Oladapo O Yeku, Hollie J Jackson, Terence J Purdon, Dayenne G van Leeuwen, Dylan J Drakes, Mei Song, Matthew M Miele, Zhuoning Li, Pei Wang,[...]. Nat Biotechnol 2018
Sarwish Rafiq, Oladapo O Yeku, Hollie J Jackson, Terence J Purdon, Dayenne G van Leeuwen, Dylan J Drakes, Mei Song, Matthew M Miele, Zhuoning Li, Pei Wang,[...]. Nat Biotechnol 2018
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Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition.
Leonid Cherkassky, Aurore Morello, Jonathan Villena-Vargas, Yang Feng, Dimiter S Dimitrov, David R Jones, Michel Sadelain, Prasad S Adusumilli. J Clin Invest 2016
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Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication.
Christopher C Kloss, Jihyun Lee, Aaron Zhang, Fang Chen, Jan Joseph Melenhorst, Simon F Lacey, Marcela V Maus, Joseph A Fraietta, Yangbing Zhao, Carl H June. Mol Ther 2018
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Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting.
Shivani Srivastava, Alexander I Salter, Denny Liggitt, Sushma Yechan-Gunja, Megha Sarvothama, Kirsten Cooper, Kimberly S Smythe, Jarrod A Dudakov, Robert H Pierce, Christoph Rader,[...]. Cancer Cell 2019
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Inducible apoptosis as a safety switch for adoptive cell therapy.
Antonio Di Stasi, Siok-Keen Tey, Gianpietro Dotti, Yuriko Fujita, Alana Kennedy-Nasser, Caridad Martinez, Karin Straathof, Enli Liu, April G Durett, Bambi Grilley,[...]. N Engl J Med 2011
Antonio Di Stasi, Siok-Keen Tey, Gianpietro Dotti, Yuriko Fujita, Alana Kennedy-Nasser, Caridad Martinez, Karin Straathof, Enli Liu, April G Durett, Bambi Grilley,[...]. N Engl J Med 2011
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Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: clinical evaluation and management of on-target toxicity.
Cor Hj Lamers, Stefan Sleijfer, Sabine van Steenbergen, Pascal van Elzakker, Brigitte van Krimpen, Corrien Groot, Arnold Vulto, Michael den Bakker, Egbert Oosterwijk, Reno Debets,[...]. Mol Ther 2013
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Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma.
Noopur Raje, Jesus Berdeja, Yi Lin, David Siegel, Sundar Jagannath, Deepu Madduri, Michaela Liedtke, Jacalyn Rosenblatt, Marcela V Maus, Ashley Turka,[...]. N Engl J Med 2019
Noopur Raje, Jesus Berdeja, Yi Lin, David Siegel, Sundar Jagannath, Deepu Madduri, Michaela Liedtke, Jacalyn Rosenblatt, Marcela V Maus, Ashley Turka,[...]. N Engl J Med 2019
14
Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma.
Nabil Ahmed, Vita S Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder,[...]. J Clin Oncol 2015
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Current concepts in the diagnosis and management of cytokine release syndrome.
Daniel W Lee, Rebecca Gardner, David L Porter, Chrystal U Louis, Nabil Ahmed, Michael Jensen, Stephan A Grupp, Crystal L Mackall. Blood 2014
Daniel W Lee, Rebecca Gardner, David L Porter, Chrystal U Louis, Nabil Ahmed, Michael Jensen, Stephan A Grupp, Crystal L Mackall. Blood 2014
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Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia.
Marco L Davila, Isabelle Riviere, Xiuyan Wang, Shirley Bartido, Jae Park, Kevin Curran, Stephen S Chung, Jolanta Stefanski, Oriana Borquez-Ojeda, Malgorzata Olszewska,[...]. Sci Transl Med 2014
Marco L Davila, Isabelle Riviere, Xiuyan Wang, Shirley Bartido, Jae Park, Kevin Curran, Stephen S Chung, Jolanta Stefanski, Oriana Borquez-Ojeda, Malgorzata Olszewska,[...]. Sci Transl Med 2014
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Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors.
Z Eshhar, T Waks, G Gross, D G Schindler. Proc Natl Acad Sci U S A 1993
Z Eshhar, T Waks, G Gross, D G Schindler. Proc Natl Acad Sci U S A 1993
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TRUCKs: the fourth generation of CARs.
Markus Chmielewski, Hinrich Abken. Expert Opin Biol Ther 2015
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Engineering strategies to overcome the current roadblocks in CAR T cell therapy.
Sarwish Rafiq, Christopher S Hackett, Renier J Brentjens. Nat Rev Clin Oncol 2020
Sarwish Rafiq, Christopher S Hackett, Renier J Brentjens. Nat Rev Clin Oncol 2020
14
Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells.
Margherita Norelli, Barbara Camisa, Giulia Barbiera, Laura Falcone, Ayurzana Purevdorj, Marco Genua, Francesca Sanvito, Maurilio Ponzoni, Claudio Doglioni, Patrizia Cristofori,[...]. Nat Med 2018
Margherita Norelli, Barbara Camisa, Giulia Barbiera, Laura Falcone, Ayurzana Purevdorj, Marco Genua, Francesca Sanvito, Maurilio Ponzoni, Claudio Doglioni, Patrizia Cristofori,[...]. Nat Med 2018
13
Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b.
John A Craddock, An Lu, Adham Bear, Martin Pule, Malcolm K Brenner, Cliona M Rooney, Aaron E Foster. J Immunother 2010
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Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies.
Marco Ruella, David M Barrett, Saad S Kenderian, Olga Shestova, Ted J Hofmann, Jessica Perazzelli, Michael Klichinsky, Vania Aikawa, Farzana Nazimuddin, Miroslaw Kozlowski,[...]. J Clin Invest 2016
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T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model.
Antonio Di Stasi, Biagio De Angelis, Cliona M Rooney, Lan Zhang, Aruna Mahendravada, Aaron E Foster, Helen E Heslop, Malcolm K Brenner, Gianpietro Dotti, Barbara Savoldo. Blood 2009
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Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas.
Stephen J Schuster, Jakub Svoboda, Elise A Chong, Sunita D Nasta, Anthony R Mato, Özlem Anak, Jennifer L Brogdon, Iulian Pruteanu-Malinici, Vijay Bhoj, Daniel Landsburg,[...]. N Engl J Med 2017
Stephen J Schuster, Jakub Svoboda, Elise A Chong, Sunita D Nasta, Anthony R Mato, Özlem Anak, Jennifer L Brogdon, Iulian Pruteanu-Malinici, Vijay Bhoj, Daniel Landsburg,[...]. N Engl J Med 2017
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Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity.
G Gross, T Waks, Z Eshhar. Proc Natl Acad Sci U S A 1989
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Remote control of therapeutic T cells through a small molecule-gated chimeric receptor.
Chia-Yung Wu, Kole T Roybal, Elias M Puchner, James Onuffer, Wendell A Lim. Science 2015
Chia-Yung Wu, Kole T Roybal, Elias M Puchner, James Onuffer, Wendell A Lim. Science 2015
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Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma.
Christine E Brown, Behnam Badie, Michael E Barish, Lihong Weng, Julie R Ostberg, Wen-Chung Chang, Araceli Naranjo, Renate Starr, Jamie Wagner, Christine Wright,[...]. Clin Cancer Res 2015
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CAR T cell immunotherapy for human cancer.
Carl H June, Roddy S O'Connor, Omkar U Kawalekar, Saba Ghassemi, Michael C Milone. Science 2018
Carl H June, Roddy S O'Connor, Omkar U Kawalekar, Saba Ghassemi, Michael C Milone. Science 2018
13
Affinity-Tuned ErbB2 or EGFR Chimeric Antigen Receptor T Cells Exhibit an Increased Therapeutic Index against Tumors in Mice.
Xiaojun Liu, Shuguang Jiang, Chongyun Fang, Shiyu Yang, Devvora Olalere, Edward C Pequignot, Alexandria P Cogdill, Na Li, Melissa Ramones, Brian Granda,[...]. Cancer Res 2015
Xiaojun Liu, Shuguang Jiang, Chongyun Fang, Shiyu Yang, Devvora Olalere, Edward C Pequignot, Alexandria P Cogdill, Na Li, Melissa Ramones, Brian Granda,[...]. Cancer Res 2015
13
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection.
Justin Eyquem, Jorge Mansilla-Soto, Theodoros Giavridis, Sjoukje J C van der Stegen, Mohamad Hamieh, Kristen M Cunanan, Ashlesha Odak, Mithat Gönen, Michel Sadelain. Nature 2017
Justin Eyquem, Jorge Mansilla-Soto, Theodoros Giavridis, Sjoukje J C van der Stegen, Mohamad Hamieh, Kristen M Cunanan, Ashlesha Odak, Mithat Gönen, Michel Sadelain. Nature 2017
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CAR T cell-induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade.
Theodoros Giavridis, Sjoukje J C van der Stegen, Justin Eyquem, Mohamad Hamieh, Alessandra Piersigilli, Michel Sadelain. Nat Med 2018
Theodoros Giavridis, Sjoukje J C van der Stegen, Justin Eyquem, Mohamad Hamieh, Alessandra Piersigilli, Michel Sadelain. Nat Med 2018
12
HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial.
Nabil Ahmed, Vita Brawley, Meenakshi Hegde, Kevin Bielamowicz, Mamta Kalra, Daniel Landi, Catherine Robertson, Tara L Gray, Oumar Diouf, Amanda Wakefield,[...]. JAMA Oncol 2017
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CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia.
Renier J Brentjens, Marco L Davila, Isabelle Riviere, Jae Park, Xiuyan Wang, Lindsay G Cowell, Shirley Bartido, Jolanta Stefanski, Clare Taylor, Malgorzata Olszewska,[...]. Sci Transl Med 2013
Renier J Brentjens, Marco L Davila, Isabelle Riviere, Jae Park, Xiuyan Wang, Lindsay G Cowell, Shirley Bartido, Jolanta Stefanski, Clare Taylor, Malgorzata Olszewska,[...]. Sci Transl Med 2013
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The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity.
Fiona C Thistlethwaite, David E Gilham, Ryan D Guest, Dominic G Rothwell, Manon Pillai, Deborah J Burt, Andrea J Byatte, Natalia Kirillova, Juan W Valle, Surinder K Sharma,[...]. Cancer Immunol Immunother 2017
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12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.