Joshua A Harrill, Theresa M Freudenrich, Dave W Machacek, Steven L Stice, William R Mundy. Neurotoxicology 2010
Times Cited: 76
Times Cited: 76
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Developmental neurotoxicity testing in vitro: models for assessing chemical effects on neurite outgrowth.
Nicholas M Radio, William R Mundy. Neurotoxicology 2008
Nicholas M Radio, William R Mundy. Neurotoxicology 2008
31
30
Use of high content image analysis to detect chemical-induced changes in synaptogenesis in vitro.
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
30
Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening.
Nicholas M Radio, Joseph M Breier, Timothy J Shafer, William R Mundy. Toxicol Sci 2008
Nicholas M Radio, Joseph M Breier, Timothy J Shafer, William R Mundy. Toxicol Sci 2008
26
Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals.
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
23
Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures.
Nina V Stiegler, Anne K Krug, Florian Matt, Marcel Leist. Toxicol Sci 2011
Nina V Stiegler, Anne K Krug, Florian Matt, Marcel Leist. Toxicol Sci 2011
23
Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells.
Joseph M Breier, Nicholas M Radio, William R Mundy, Timothy J Shafer. Toxicol Sci 2008
Joseph M Breier, Nicholas M Radio, William R Mundy, Timothy J Shafer. Toxicol Sci 2008
22
Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth.
Joshua A Harrill, Theresa M Freudenrich, Brian L Robinette, William R Mundy. Toxicol Appl Pharmacol 2011
Joshua A Harrill, Theresa M Freudenrich, Brian L Robinette, William R Mundy. Toxicol Appl Pharmacol 2011
34
Evaluation of a human neurite growth assay as specific screen for developmental neurotoxicants.
Anne K Krug, Nina V Balmer, Florian Matt, Felix Schönenberger, Dorit Merhof, Marcel Leist. Arch Toxicol 2013
Anne K Krug, Nina V Balmer, Florian Matt, Felix Schönenberger, Dorit Merhof, Marcel Leist. Arch Toxicol 2013
21
Comparison of PC12 and cerebellar granule cell cultures for evaluating neurite outgrowth using high content analysis.
Nicholas M Radio, Theresa M Freudenrich, Brian L Robinette, Kevin M Crofton, William R Mundy. Neurotoxicol Teratol 2010
Nicholas M Radio, Theresa M Freudenrich, Brian L Robinette, Kevin M Crofton, William R Mundy. Neurotoxicol Teratol 2010
31
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing.
Philipp B Kuegler, Bastian Zimmer, Tanja Waldmann, Birte Baudis, Sten Ilmjärv, Jürgen Hescheler, Phil Gaughwin, Patrik Brundin, William Mundy, Anna K Bal-Price,[...]. ALTEX 2010
Philipp B Kuegler, Bastian Zimmer, Tanja Waldmann, Birte Baudis, Sten Ilmjärv, Jürgen Hescheler, Phil Gaughwin, Patrik Brundin, William Mundy, Anna K Bal-Price,[...]. ALTEX 2010
18
Neurobehavioural effects of developmental toxicity.
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
18
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.
Anna Bal-Price, Kevin M Crofton, Marcel Leist, Sandra Allen, Michael Arand, Timo Buetler, Nathalie Delrue, Rex E FitzGerald, Thomas Hartung, Tuula Heinonen,[...]. Arch Toxicol 2015
Anna Bal-Price, Kevin M Crofton, Marcel Leist, Sandra Allen, Michael Arand, Timo Buetler, Nathalie Delrue, Rex E FitzGerald, Thomas Hartung, Tuula Heinonen,[...]. Arch Toxicol 2015
18
Human neurospheres as three-dimensional cellular systems for developmental neurotoxicity testing.
Michaela Moors, Thomas Dino Rockel, Josef Abel, Jason E Cline, Kathrin Gassmann, Timm Schreiber, Janette Schuwald, Nicole Weinmann, Ellen Fritsche. Environ Health Perspect 2009
Michaela Moors, Thomas Dino Rockel, Josef Abel, Jason E Cline, Kathrin Gassmann, Timm Schreiber, Janette Schuwald, Nicole Weinmann, Ellen Fritsche. Environ Health Perspect 2009
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Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells.
Bastian Zimmer, Gabsang Lee, Nina V Balmer, Kesavan Meganathan, Agapios Sachinidis, Lorenz Studer, Marcel Leist. Environ Health Perspect 2012
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18
Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation.
Anna K Bal-Price, Sandra Coecke, Lucio Costa, Kevin M Crofton, Ellen Fritsche, Alan Goldberg, Philippe Grandjean, Pamela J Lein, Abby Li, Roberto Lucchini,[...]. ALTEX 2012
Anna K Bal-Price, Sandra Coecke, Lucio Costa, Kevin M Crofton, Ellen Fritsche, Alan Goldberg, Philippe Grandjean, Pamela J Lein, Abby Li, Roberto Lucchini,[...]. ALTEX 2012
17
Neuronal models for evaluation of proliferation in vitro using high content screening.
William R Mundy, Nicholas M Radio, Theresa M Freudenrich. Toxicology 2010
William R Mundy, Nicholas M Radio, Theresa M Freudenrich. Toxicology 2010
31
Embryonic stem cell lines derived from human blastocysts.
J A Thomson, J Itskovitz-Eldor, S S Shapiro, M A Waknitz, J J Swiergiel, V S Marshall, J M Jones. Science 1998
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Compound selection for in vitro modeling of developmental neurotoxicity.
Suzanne Kadereit, Bastian Zimmer, Christoph van Thriel, Jan G Hengstler, Marcel Leist. Front Biosci (Landmark Ed) 2012
Suzanne Kadereit, Bastian Zimmer, Christoph van Thriel, Jan G Hengstler, Marcel Leist. Front Biosci (Landmark Ed) 2012
20
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.
Anne K Krug, Raivo Kolde, John A Gaspar, Eugen Rempel, Nina V Balmer, Kesavan Meganathan, Kinga Vojnits, Mathurin Baquié, Tanja Waldmann, Roberto Ensenat-Waser,[...]. Arch Toxicol 2013
Anne K Krug, Raivo Kolde, John A Gaspar, Eugen Rempel, Nina V Balmer, Kesavan Meganathan, Kinga Vojnits, Mathurin Baquié, Tanja Waldmann, Roberto Ensenat-Waser,[...]. Arch Toxicol 2013
15
Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities.
Lena Smirnova, Helena T Hogberg, Marcel Leist, Thomas Hartung. ALTEX 2014
Lena Smirnova, Helena T Hogberg, Marcel Leist, Thomas Hartung. ALTEX 2014
15
Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies.
Sandra Coecke, Alan M Goldberg, Sandra Allen, Leonora Buzanska, Gemma Calamandrei, Kevin Crofton, Lars Hareng, Thomas Hartung, Holger Knaut, Paul Honegger,[...]. Environ Health Perspect 2007
Sandra Coecke, Alan M Goldberg, Sandra Allen, Leonora Buzanska, Gemma Calamandrei, Kevin Crofton, Lars Hareng, Thomas Hartung, Holger Knaut, Paul Honegger,[...]. Environ Health Perspect 2007
14
Meeting report: alternatives for developmental neurotoxicity testing.
Pamela Lein, Paul Locke, Alan Goldberg. Environ Health Perspect 2007
Pamela Lein, Paul Locke, Alan Goldberg. Environ Health Perspect 2007
14
Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing.
B Zimmer, P B Kuegler, B Baudis, A Genewsky, V Tanavde, W Koh, B Tan, T Waldmann, S Kadereit, M Leist. Cell Death Differ 2011
B Zimmer, P B Kuegler, B Baudis, A Genewsky, V Tanavde, W Koh, B Tan, T Waldmann, S Kadereit, M Leist. Cell Death Differ 2011
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Hazard assessment of methylmercury toxicity to neuronal induction in embryogenesis using human embryonic stem cells.
Tina C Stummann, Lars Hareng, Susanne Bremer. Toxicology 2009
Tina C Stummann, Lars Hareng, Susanne Bremer. Toxicology 2009
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In vitro assessment of developmental neurotoxicity: use of microelectrode arrays to measure functional changes in neuronal network ontogeny.
Brian L Robinette, Joshua A Harrill, William R Mundy, Timothy J Shafer. Front Neuroeng 2011
Brian L Robinette, Joshua A Harrill, William R Mundy, Timothy J Shafer. Front Neuroeng 2011
14
Use of high content image analyses to detect chemical-mediated effects on neurite sub-populations in primary rat cortical neurons.
Joshua A Harrill, Brian L Robinette, Theresa Freudenrich, William R Mundy. Neurotoxicology 2013
Joshua A Harrill, Brian L Robinette, Theresa Freudenrich, William R Mundy. Neurotoxicology 2013
25
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery.
B Zimmer, G Pallocca, N Dreser, S Foerster, T Waldmann, J Westerhout, S Julien, K H Krause, C van Thriel, J G Hengstler,[...]. Arch Toxicol 2014
B Zimmer, G Pallocca, N Dreser, S Foerster, T Waldmann, J Westerhout, S Julien, K H Krause, C van Thriel, J G Hengstler,[...]. Arch Toxicol 2014
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Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.
D Rice, S Barone. Environ Health Perspect 2000
D Rice, S Barone. Environ Health Perspect 2000
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In vitro developmental neurotoxicity (DNT) testing: relevant models and endpoints.
Anna K Bal-Price, Helena T Hogberg, Leonora Buzanska, Petros Lenas, Erwin van Vliet, Thomas Hartung. Neurotoxicology 2010
Anna K Bal-Price, Helena T Hogberg, Leonora Buzanska, Petros Lenas, Erwin van Vliet, Thomas Hartung. Neurotoxicology 2010
14
Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts.
Christoph van Thriel, Remco H S Westerink, Christian Beste, Ambuja S Bale, Pamela J Lein, Marcel Leist. Neurotoxicology 2012
Christoph van Thriel, Remco H S Westerink, Christian Beste, Ambuja S Bale, Pamela J Lein, Marcel Leist. Neurotoxicology 2012
14
Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells.
Megan E Culbreth, Joshua A Harrill, Theresa M Freudenrich, William R Mundy, Timothy J Shafer. Neurotoxicology 2012
Megan E Culbreth, Joshua A Harrill, Theresa M Freudenrich, William R Mundy, Timothy J Shafer. Neurotoxicology 2012
19
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.
Stuart M Chambers, Christopher A Fasano, Eirini P Papapetrou, Mark Tomishima, Michel Sadelain, Lorenz Studer. Nat Biotechnol 2009
Stuart M Chambers, Christopher A Fasano, Eirini P Papapetrou, Mark Tomishima, Michel Sadelain, Lorenz Studer. Nat Biotechnol 2009
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Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome.
Nina V Balmer, Matthias K Weng, Bastian Zimmer, Violeta N Ivanova, Stuart M Chambers, Elena Nikolaeva, Smita Jagtap, Agapios Sachinidis, Jürgen Hescheler, Tanja Waldmann,[...]. Hum Mol Genet 2012
Nina V Balmer, Matthias K Weng, Bastian Zimmer, Violeta N Ivanova, Stuart M Chambers, Elena Nikolaeva, Smita Jagtap, Agapios Sachinidis, Jürgen Hescheler, Tanja Waldmann,[...]. Hum Mol Genet 2012
12
Multi-well microelectrode array recordings detect neuroactivity of ToxCast compounds.
Pablo Valdivia, Matt Martin, William R LeFew, James Ross, Keith A Houck, Timothy J Shafer. Neurotoxicology 2014
Pablo Valdivia, Matt Martin, William R LeFew, James Ross, Keith A Houck, Timothy J Shafer. Neurotoxicology 2014
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Omnisphero: a high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro.
Martin R Schmuck, Thomas Temme, Katharina Dach, Denise de Boer, Marta Barenys, Farina Bendt, Axel Mosig, Ellen Fritsche. Arch Toxicol 2017
Martin R Schmuck, Thomas Temme, Katharina Dach, Denise de Boer, Marta Barenys, Farina Bendt, Axel Mosig, Ellen Fritsche. Arch Toxicol 2017
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A neuronal and astrocyte co-culture assay for high content analysis of neurotoxicity.
Janet L Anderl, Stella Redpath, Andrew J Ball. J Vis Exp 2009
Janet L Anderl, Stella Redpath, Andrew J Ball. J Vis Exp 2009
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Application of micro-electrode arrays (MEAs) as an emerging technology for developmental neurotoxicity: evaluation of domoic acid-induced effects in primary cultures of rat cortical neurons.
Helena T Hogberg, Tomasz Sobanski, Antonio Novellino, Maurice Whelan, Dieter G Weiss, Anna K Bal-Price. Neurotoxicology 2011
Helena T Hogberg, Tomasz Sobanski, Antonio Novellino, Maurice Whelan, Dieter G Weiss, Anna K Bal-Price. Neurotoxicology 2011
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Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka. Cell 2007
Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka. Cell 2007
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An in vitro model of human dopaminergic neurons derived from embryonic stem cells: MPP+ toxicity and GDNF neuroprotection.
Xianmin Zeng, Jia Chen, Xiaolin Deng, Ying Liu, Mahendra S Rao, Jean-Lud Cadet, William J Freed. Neuropsychopharmacology 2006
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Putative adverse outcome pathways relevant to neurotoxicity.
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
11
Developmental neurotoxicity guideline study: issues with methodology, evaluation and regulation.
Ryozo Tsuji, Kevin M Crofton. Congenit Anom (Kyoto) 2012
Ryozo Tsuji, Kevin M Crofton. Congenit Anom (Kyoto) 2012
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Cerebral organoids model human brain development and microcephaly.
Madeline A Lancaster, Magdalena Renner, Carol-Anne Martin, Daniel Wenzel, Louise S Bicknell, Matthew E Hurles, Tessa Homfray, Josef M Penninger, Andrew P Jackson, Juergen A Knoblich. Nature 2013
Madeline A Lancaster, Magdalena Renner, Carol-Anne Martin, Daniel Wenzel, Louise S Bicknell, Matthew E Hurles, Tessa Homfray, Josef M Penninger, Andrew P Jackson, Juergen A Knoblich. Nature 2013
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Sensitivity of neuroprogenitor cells to chemical-induced apoptosis using a multiplexed assay suitable for high-throughput screening.
Ingrid Druwe, Theresa M Freudenrich, Kathleen Wallace, Timothy J Shafer, William R Mundy. Toxicology 2015
Ingrid Druwe, Theresa M Freudenrich, Kathleen Wallace, Timothy J Shafer, William R Mundy. Toxicology 2015
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Expanding the test set: Chemicals with potential to disrupt mammalian brain development.
William R Mundy, Stephanie Padilla, Joseph M Breier, Kevin M Crofton, Mary E Gilbert, David W Herr, Karl F Jensen, Nicholas M Radio, Kathleen C Raffaele, Kelly Schumacher,[...]. Neurotoxicol Teratol 2015
William R Mundy, Stephanie Padilla, Joseph M Breier, Kevin M Crofton, Mary E Gilbert, David W Herr, Karl F Jensen, Nicholas M Radio, Kathleen C Raffaele, Kelly Schumacher,[...]. Neurotoxicol Teratol 2015
14
Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity.
Kristen R Ryan, Oksana Sirenko, Fred Parham, Jui-Hua Hsieh, Evan F Cromwell, Raymond R Tice, Mamta Behl. Neurotoxicology 2016
Kristen R Ryan, Oksana Sirenko, Fred Parham, Jui-Hua Hsieh, Evan F Cromwell, Raymond R Tice, Mamta Behl. Neurotoxicology 2016
10
OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.
Ellen Fritsche, Kevin M Crofton, Antonio F Hernandez, Susanne Hougaard Bennekou, Marcel Leist, Anna Bal-Price, Elissa Reaves, Martin F Wilks, Andrea Terron, Roland Solecki,[...]. ALTEX 2017
Ellen Fritsche, Kevin M Crofton, Antonio F Hernandez, Susanne Hougaard Bennekou, Marcel Leist, Anna Bal-Price, Elissa Reaves, Martin F Wilks, Andrea Terron, Roland Solecki,[...]. ALTEX 2017
14
Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.
Michael Aschner, Sandra Ceccatelli, Mardas Daneshian, Ellen Fritsche, Nina Hasiwa, Thomas Hartung, Helena T Hogberg, Marcel Leist, Abby Li, William R Mundi,[...]. ALTEX 2017
Michael Aschner, Sandra Ceccatelli, Mardas Daneshian, Ellen Fritsche, Nina Hasiwa, Thomas Hartung, Helena T Hogberg, Marcel Leist, Abby Li, William R Mundi,[...]. ALTEX 2017
10
In vitro and other alternative approaches to developmental neurotoxicity testing (DNT).
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A retrospective performance assessment of the developmental neurotoxicity study in support of OECD test guideline 426.
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9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.