Kate Schroder, Jurg Tschopp. Cell 2010
Times Cited: 3287
Times Cited: 3287
Times Cited
Times Co-cited
Similarity
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
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Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta.
Fabio Martinon, Kimberly Burns, Jürg Tschopp. Mol Cell 2002
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A role for mitochondria in NLRP3 inflammasome activation.
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Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
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Activation and regulation of the inflammasomes.
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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
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NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
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Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
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The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis.
Luigi Franchi, Tatjana Eigenbrod, Raúl Muñoz-Planillo, Gabriel Nuñez. Nat Immunol 2009
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Targeting the NLRP3 inflammasome in inflammatory diseases.
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Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors.
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The inflammasomes: guardians of the body.
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Thioredoxin-interacting protein links oxidative stress to inflammasome activation.
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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
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Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death.
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Pore-forming activity and structural autoinhibition of the gasdermin family.
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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
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Molecular mechanisms regulating NLRP3 inflammasome activation.
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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
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Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
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Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.
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The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.
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Initiation and perpetuation of NLRP3 inflammasome activation and assembly.
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Pyroptosis: host cell death and inflammation.
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Sensing and reacting to microbes through the inflammasomes.
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Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome.
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Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation.
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Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP.
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Gout-associated uric acid crystals activate the NALP3 inflammasome.
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NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies.
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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
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Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.
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K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
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NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.
Yuan He, Melody Y Zeng, Dahai Yang, Benny Motro, Gabriel Núñez. Nature 2016
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A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes.
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The inflammasome NLRs in immunity, inflammation, and associated diseases.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.