A citation-based method for searching scientific literature

David Fernandez, Andras Perl. Discov Med 2010
Times Cited: 70







List of co-cited articles
732 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus.
David Fernandez, Eduardo Bonilla, Naureen Mirza, Brian Niland, Andras Perl. Arthritis Rheum 2006
200
35

Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus.
Peter Gergely, Craig Grossman, Brian Niland, Ferenc Puskas, Hom Neupane, Fatme Allam, Katalin Banki, Paul E Phillips, Andras Perl. Arthritis Rheum 2002
201
21

Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
David R Fernandez, Tiffany Telarico, Eduardo Bonilla, Qing Li, Sanjay Banerjee, Frank A Middleton, Paul E Phillips, Mary K Crow, Stefanie Oess, Werner Muller-Esterl,[...]. J Immunol 2009
148
21

N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.
Zhi-Wei Lai, Robert Hanczko, Eduardo Bonilla, Tiffany N Caza, Brandon Clair, Adam Bartos, Gabriella Miklossy, John Jimah, Edward Doherty, Hajra Tily,[...]. Arthritis Rheum 2012
194
20

Normalization of CD4+ T cell metabolism reverses lupus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Daniel J Perry, Howard Seay, Byron P Croker, Eric S Sobel, Todd M Brusko, Laurence Morel. Sci Transl Med 2015
288
20

Metabolic control of T cell activation and death in SLE.
David Fernandez, Andras Perl. Autoimmun Rev 2009
70
18

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.
Lewis Z Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R Green, Hongbo Chi. J Exp Med 2011
970
18



The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Greg M Delgoffe, Kristen N Pollizzi, Adam T Waickman, Emily Heikamp, David J Meyers, Maureen R Horton, Bo Xiao, Paul F Worley, Jonathan D Powell. Nat Immunol 2011
704
15


Rapamycin attenuates the severity of established nephritis in lupus-prone NZB/W F1 mice.
Sing Leung Lui, Ryan Tsang, Kwok Wah Chan, Florence Zhang, Sidney Tam, Susan Yung, Tak Mao Chan. Nephrol Dial Transplant 2008
56
19


Regulation of immune responses by mTOR.
Jonathan D Powell, Kristen N Pollizzi, Emily B Heikamp, Maureen R Horton. Annu Rev Immunol 2012
482
14

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
Ryan D Michalek, Valerie A Gerriets, Sarah R Jacobs, Andrew N Macintyre, Nancie J MacIver, Emily F Mason, Sarah A Sullivan, Amanda G Nichols, Jeffrey C Rathmell. J Immunol 2011
14

Abnormalities of T cell signaling in systemic lupus erythematosus.
Vaishali R Moulton, George C Tsokos. Arthritis Res Ther 2011
113
14

Systemic lupus erythematosus.
George C Tsokos. N Engl J Med 2011
14

mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.
Hu Zeng, Kai Yang, Caryn Cloer, Geoffrey Neale, Peter Vogel, Hongbo Chi. Nature 2013
454
14

Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.
Zhi-Wei Lai, Ryan Kelly, Thomas Winans, Ivan Marchena, Ashwini Shadakshari, Julie Yu, Maha Dawood, Ricardo Garcia, Hajra Tily, Lisa Francis,[...]. Lancet 2018
147
14

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.
Greg M Delgoffe, Thomas P Kole, Yan Zheng, Paul E Zarek, Krystal L Matthews, Bo Xiao, Paul F Worley, Sara C Kozma, Jonathan D Powell. Immunity 2009
776
12

Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population.
Xu-jie Zhou, Xiao-lan Lu, Ji-cheng Lv, Hai-zhen Yang, Lian-xiang Qin, Ming-hui Zhao, Yin Su, Zhan-guo Li, Hong Zhang. Ann Rheum Dis 2011
140
12


Tuberous sclerosis and fulminant lupus in a young woman.
Namrata Singh, Mark Birkenbach, Tiffany Caza, Andras Perl, Philip L Cohen. J Clin Rheumatol 2013
19
47

Glucose Oxidation Is Critical for CD4+ T Cell Activation in a Mouse Model of Systemic Lupus Erythematosus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Leilani Zeumer, Nathalie Kanda, Byron P Croker, Laurence Morel. J Immunol 2016
73
12

Immunometabolism in systemic lupus erythematosus.
Laurence Morel. Nat Rev Rheumatol 2017
96
12


The CD28 signaling pathway regulates glucose metabolism.
Kenneth A Frauwirth, James L Riley, Marian H Harris, Richard V Parry, Jeffrey C Rathmell, David R Plas, Rebecca L Elstrom, Carl H June, Craig B Thompson. Immunity 2002
832
11

Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus.
Zhi-Wei Lai, Rebecca Borsuk, Ashwini Shadakshari, Jianghong Yu, Maha Dawood, Ricardo Garcia, Lisa Francis, Hajra Tily, Adam Bartos, Stephen V Faraone,[...]. J Immunol 2013
75
11

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.
Luciana Berod, Christin Friedrich, Amrita Nandan, Jenny Freitag, Stefanie Hagemann, Kirsten Harmrolfs, Aline Sandouk, Christina Hesse, Carla N Castro, Heike Bähre,[...]. Nat Med 2014
397
11

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
John B Harley, Marta E Alarcón-Riquelme, Lindsey A Criswell, Chaim O Jacob, Robert P Kimberly, Kathy L Moser, Betty P Tsao, Timothy J Vyse, Carl D Langefeld, Swapan K Nath,[...]. Nat Genet 2008
939
10

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.
Jian-Wen Han, Hou-Feng Zheng, Yong Cui, Liang-Dan Sun, Dong-Qing Ye, Zhi Hu, Jin-Hua Xu, Zhi-Ming Cai, Wei Huang, Guo-Ping Zhao,[...]. Nat Genet 2009
675
10

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.
Ruoning Wang, Christopher P Dillon, Lewis Zhichang Shi, Sandra Milasta, Robert Carter, David Finkelstein, Laura L McCormick, Patrick Fitzgerald, Hongbo Chi, Joshua Munger,[...]. Immunity 2011
10

Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin.
Andras Perl, Robert Hanczko, Zhi-Wei Lai, Zachary Oaks, Ryan Kelly, Rebecca Borsuk, John M Asara, Paul E Phillips. Metabolomics 2015
65
10

The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.
Andrew N Macintyre, Valerie A Gerriets, Amanda G Nichols, Ryan D Michalek, Michael C Rudolph, Divino Deoliveira, Steven M Anderson, E Dale Abel, Benny J Chen, Laura P Hale,[...]. Cell Metab 2014
502
10

Normalizing glycosphingolipids restores function in CD4+ T cells from lupus patients.
Georgia McDonald, Shantal Deepak, Laura Miguel, Cleo J Hall, David A Isenberg, Anthony I Magee, Terry Butters, Elizabeth C Jury. J Clin Invest 2014
81
10

T-cell and B-cell signaling biomarkers and treatment targets in lupus.
Andras Perl, David R Fernandez, Tiffany Telarico, Edward Doherty, Lisa Francis, Paul E Phillips. Curr Opin Rheumatol 2009
32
18

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.
Katrin Düvel, Jessica L Yecies, Suchithra Menon, Pichai Raman, Alex I Lipovsky, Amanda L Souza, Ellen Triantafellow, Qicheng Ma, Regina Gorski, Stephen Cleaver,[...]. Mol Cell 2010
8

Nitric oxide-dependent mitochondrial biogenesis generates Ca2+ signaling profile of lupus T cells.
Gyorgy Nagy, Maureen Barcza, Nick Gonchoroff, Paul E Phillips, Andras Perl. J Immunol 2004
80
8

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.
Vesela Gateva, Johanna K Sandling, Geoff Hom, Kimberly E Taylor, Sharon A Chung, Xin Sun, Ward Ortmann, Roman Kosoy, Ricardo C Ferreira, Gunnel Nordmark,[...]. Nat Genet 2009
586
8

Systemic lupus erythematosus.
Anisur Rahman, David A Isenberg. N Engl J Med 2008
8

Enhancing CD8 T-cell memory by modulating fatty acid metabolism.
Erika L Pearce, Matthew C Walsh, Pedro J Cejas, Gretchen M Harms, Hao Shen, Li-San Wang, Russell G Jones, Yongwon Choi. Nature 2009
912
8

Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus.
Marina Pierdominici, Marta Vomero, Cristiana Barbati, Tania Colasanti, Angela Maselli, Davide Vacirca, Antonello Giovannetti, Walter Malorni, Elena Ortona. FASEB J 2012
93
8

Rapamycin prevents the development of nephritis in lupus-prone NZB/W F1 mice.
S L Lui, S Yung, R Tsang, F Zhang, K W Chan, S Tam, T M Chan. Lupus 2008
42
14

T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy.
Cristiano Alessandri, Cristiana Barbati, Davide Vacirca, Paola Piscopo, Annamaria Confaloni, Massimo Sanchez, Angela Maselli, Tania Colasanti, Fabrizio Conti, Simona Truglia,[...]. FASEB J 2012
90
8

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus.
Michelle Petri, Ana-Maria Orbai, Graciela S Alarcón, Caroline Gordon, Joan T Merrill, Paul R Fortin, Ian N Bruce, David Isenberg, Daniel J Wallace, Ola Nived,[...]. Arthritis Rheum 2012
8

Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.
Laura A Sena, Sha Li, Amit Jairaman, Murali Prakriya, Teresa Ezponda, David A Hildeman, Chyung-Ru Wang, Paul T Schumacker, Jonathan D Licht, Harris Perlman,[...]. Immunity 2013
592
8

Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.
Sarah R Jacobs, Catherine E Herman, Nancie J Maciver, Jessica A Wofford, Heather L Wieman, Jeremy J Hammen, Jeffrey C Rathmell. J Immunol 2008
451
8

Murine lupus susceptibility locus Sle1c2 mediates CD4+ T cell activation and maps to estrogen-related receptor γ.
Daniel J Perry, Yiming Yin, Tiffany Telarico, Henry V Baker, Igor Dozmorov, Andras Perl, Laurence Morel. J Immunol 2012
34
17

Metabolic regulation of T lymphocytes.
Nancie J MacIver, Ryan D Michalek, Jeffrey C Rathmell. Annu Rev Immunol 2013
662
8

Mitochondrial dysfunction in T cells of patients with systemic lupus erythematosus.
Andras Perl, Peter Gergely, Katalin Banki. Int Rev Immunol 2004
45
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.