Luigi Fontana, Linda Partridge, Valter D Longo. Science 2010
Times Cited: 1776
Times Cited: 1776
Times Cited
Times Co-cited
Similarity
The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
30
Promoting health and longevity through diet: from model organisms to humans.
Luigi Fontana, Linda Partridge. Cell 2015
Luigi Fontana, Linda Partridge. Cell 2015
16
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
David E Harrison, Randy Strong, Zelton Dave Sharp, James F Nelson, Clinton M Astle, Kevin Flurkey, Nancy L Nadon, J Erby Wilkinson, Krystyna Frenkel, Christy S Carter,[...]. Nature 2009
David E Harrison, Randy Strong, Zelton Dave Sharp, James F Nelson, Clinton M Astle, Kevin Flurkey, Nancy L Nadon, J Erby Wilkinson, Krystyna Frenkel, Christy S Carter,[...]. Nature 2009
14
Caloric restriction delays disease onset and mortality in rhesus monkeys.
Ricki J Colman, Rozalyn M Anderson, Sterling C Johnson, Erik K Kastman, Kristopher J Kosmatka, T Mark Beasley, David B Allison, Christina Cruzen, Heather A Simmons, Joseph W Kemnitz,[...]. Science 2009
Ricki J Colman, Rozalyn M Anderson, Sterling C Johnson, Erik K Kastman, Kristopher J Kosmatka, T Mark Beasley, David B Allison, Christina Cruzen, Heather A Simmons, Joseph W Kemnitz,[...]. Science 2009
13
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice.
Martin Holzenberger, Joëlle Dupont, Bertrand Ducos, Patricia Leneuve, Alain Géloën, Patrick C Even, Pascale Cervera, Yves Le Bouc. Nature 2003
Martin Holzenberger, Joëlle Dupont, Bertrand Ducos, Patricia Leneuve, Alain Géloën, Patrick C Even, Pascale Cervera, Yves Le Bouc. Nature 2003
12
Caloric restriction improves health and survival of rhesus monkeys.
Julie A Mattison, Ricki J Colman, T Mark Beasley, David B Allison, Joseph W Kemnitz, George S Roth, Donald K Ingram, Richard Weindruch, Rafael de Cabo, Rozalyn M Anderson. Nat Commun 2017
Julie A Mattison, Ricki J Colman, T Mark Beasley, David B Allison, Joseph W Kemnitz, George S Roth, Donald K Ingram, Richard Weindruch, Rafael de Cabo, Rozalyn M Anderson. Nat Commun 2017
10
Dietary restriction and lifespan: Lessons from invertebrate models.
Pankaj Kapahi, Matt Kaeberlein, Malene Hansen. Ageing Res Rev 2017
Pankaj Kapahi, Matt Kaeberlein, Malene Hansen. Ageing Res Rev 2017
10
Geroscience: linking aging to chronic disease.
Brian K Kennedy, Shelley L Berger, Anne Brunet, Judith Campisi, Ana Maria Cuervo, Elissa S Epel, Claudio Franceschi, Gordon J Lithgow, Richard I Morimoto, Jeffrey E Pessin,[...]. Cell 2014
Brian K Kennedy, Shelley L Berger, Anne Brunet, Judith Campisi, Ana Maria Cuervo, Elissa S Epel, Claudio Franceschi, Gordon J Lithgow, Richard I Morimoto, Jeffrey E Pessin,[...]. Cell 2014
10
Metformin improves healthspan and lifespan in mice.
Alejandro Martin-Montalvo, Evi M Mercken, Sarah J Mitchell, Hector H Palacios, Patricia L Mote, Morten Scheibye-Knudsen, Ana P Gomes, Theresa M Ward, Robin K Minor, Marie-José Blouin,[...]. Nat Commun 2013
Alejandro Martin-Montalvo, Evi M Mercken, Sarah J Mitchell, Hector H Palacios, Patricia L Mote, Morten Scheibye-Knudsen, Ana P Gomes, Theresa M Ward, Robin K Minor, Marie-José Blouin,[...]. Nat Commun 2013
9
The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935.
C M McCay, M F Crowell, L A Maynard. Nutrition 1989
C M McCay, M F Crowell, L A Maynard. Nutrition 1989
9
A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.
Sebastian Brandhorst, In Young Choi, Min Wei, Chia Wei Cheng, Sargis Sedrakyan, Gerardo Navarrete, Louis Dubeau, Li Peng Yap, Ryan Park, Manlio Vinciguerra,[...]. Cell Metab 2015
Sebastian Brandhorst, In Young Choi, Min Wei, Chia Wei Cheng, Sargis Sedrakyan, Gerardo Navarrete, Louis Dubeau, Li Peng Yap, Ryan Park, Manlio Vinciguerra,[...]. Cell Metab 2015
9
A C. elegans mutant that lives twice as long as wild type.
C Kenyon, J Chang, E Gensch, A Rudner, R Tabtiang. Nature 1993
C Kenyon, J Chang, E Gensch, A Rudner, R Tabtiang. Nature 1993
9
Impact of intermittent fasting on health and disease processes.
Mark P Mattson, Valter D Longo, Michelle Harvie. Ageing Res Rev 2017
Mark P Mattson, Valter D Longo, Michelle Harvie. Ageing Res Rev 2017
9
Metabolic Slowing and Reduced Oxidative Damage with Sustained Caloric Restriction Support the Rate of Living and Oxidative Damage Theories of Aging.
Leanne M Redman, Steven R Smith, Jeffrey H Burton, Corby K Martin, Dora Il'yasova, Eric Ravussin. Cell Metab 2018
Leanne M Redman, Steven R Smith, Jeffrey H Burton, Corby K Martin, Dora Il'yasova, Eric Ravussin. Cell Metab 2018
8
Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential.
Frank Madeo, Didac Carmona-Gutierrez, Sebastian J Hofer, Guido Kroemer. Cell Metab 2019
Frank Madeo, Didac Carmona-Gutierrez, Sebastian J Hofer, Guido Kroemer. Cell Metab 2019
8
Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.
John C Newman, Anthony J Covarrubias, Minghao Zhao, Xinxing Yu, Philipp Gut, Che-Ping Ng, Yu Huang, Saptarsi Haldar, Eric Verdin. Cell Metab 2017
John C Newman, Anthony J Covarrubias, Minghao Zhao, Xinxing Yu, Philipp Gut, Che-Ping Ng, Yu Huang, Saptarsi Haldar, Eric Verdin. Cell Metab 2017
8
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study.
Julie A Mattison, George S Roth, T Mark Beasley, Edward M Tilmont, April M Handy, Richard L Herbert, Dan L Longo, David B Allison, Jennifer E Young, Mark Bryant,[...]. Nature 2012
Julie A Mattison, George S Roth, T Mark Beasley, Edward M Tilmont, April M Handy, Richard L Herbert, Dan L Longo, David B Allison, Jennifer E Young, Mark Bryant,[...]. Nature 2012
7
Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States.
Mark P Mattson, Thiruma V Arumugam. Cell Metab 2018
Mark P Mattson, Thiruma V Arumugam. Cell Metab 2018
7
7
The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
7
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.
Colin Selman, Jennifer M A Tullet, Daniela Wieser, Elaine Irvine, Steven J Lingard, Agharul I Choudhury, Marc Claret, Hind Al-Qassab, Danielle Carmignac, Faruk Ramadani,[...]. Science 2009
Colin Selman, Jennifer M A Tullet, Daniela Wieser, Elaine Irvine, Steven J Lingard, Agharul I Choudhury, Marc Claret, Hind Al-Qassab, Danielle Carmignac, Faruk Ramadani,[...]. Science 2009
7
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.
Sarah J Mitchell, Julio Madrigal-Matute, Morten Scheibye-Knudsen, Evandro Fang, Miguel Aon, José A González-Reyes, Sonia Cortassa, Susmita Kaushik, Marta Gonzalez-Freire, Bindi Patel,[...]. Cell Metab 2016
Sarah J Mitchell, Julio Madrigal-Matute, Morten Scheibye-Knudsen, Evandro Fang, Miguel Aon, José A González-Reyes, Sonia Cortassa, Susmita Kaushik, Marta Gonzalez-Freire, Bindi Patel,[...]. Cell Metab 2016
7
Resveratrol improves health and survival of mice on a high-calorie diet.
Joseph A Baur, Kevin J Pearson, Nathan L Price, Hamish A Jamieson, Carles Lerin, Avash Kalra, Vinayakumar V Prabhu, Joanne S Allard, Guillermo Lopez-Lluch, Kaitlyn Lewis,[...]. Nature 2006
Joseph A Baur, Kevin J Pearson, Nathan L Price, Hamish A Jamieson, Carles Lerin, Avash Kalra, Vinayakumar V Prabhu, Joanne S Allard, Guillermo Lopez-Lluch, Kaitlyn Lewis,[...]. Nature 2006
7
The critical role of metabolic pathways in aging.
Nir Barzilai, Derek M Huffman, Radhika H Muzumdar, Andrzej Bartke. Diabetes 2012
Nir Barzilai, Derek M Huffman, Radhika H Muzumdar, Andrzej Bartke. Diabetes 2012
6
Endogenous hydrogen sulfide production is essential for dietary restriction benefits.
Christopher Hine, Eylul Harputlugil, Yue Zhang, Christoph Ruckenstuhl, Byung Cheon Lee, Lear Brace, Alban Longchamp, Jose H Treviño-Villarreal, Pedro Mejia, C Keith Ozaki,[...]. Cell 2015
Christopher Hine, Eylul Harputlugil, Yue Zhang, Christoph Ruckenstuhl, Byung Cheon Lee, Lear Brace, Alban Longchamp, Jose H Treviño-Villarreal, Pedro Mejia, C Keith Ozaki,[...]. Cell 2015
6
Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease.
Min Wei, Sebastian Brandhorst, Mahshid Shelehchi, Hamed Mirzaei, Chia Wei Cheng, Julia Budniak, Susan Groshen, Wendy J Mack, Esra Guen, Stefano Di Biase,[...]. Sci Transl Med 2017
Min Wei, Sebastian Brandhorst, Mahshid Shelehchi, Hamed Mirzaei, Chia Wei Cheng, Julia Budniak, Susan Groshen, Wendy J Mack, Esra Guen, Stefano Di Biase,[...]. Sci Transl Med 2017
6
Fasting-mimicking diet and hormone therapy induce breast cancer regression.
Irene Caffa, Vanessa Spagnolo, Claudio Vernieri, Francesca Valdemarin, Pamela Becherini, Min Wei, Sebastian Brandhorst, Chiara Zucal, Else Driehuis, Lorenzo Ferrando,[...]. Nature 2020
Irene Caffa, Vanessa Spagnolo, Claudio Vernieri, Francesca Valdemarin, Pamela Becherini, Min Wei, Sebastian Brandhorst, Chiara Zucal, Else Driehuis, Lorenzo Ferrando,[...]. Nature 2020
8
Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity.
Stefano Di Biase, Changhan Lee, Sebastian Brandhorst, Brianna Manes, Roberta Buono, Chia-Wei Cheng, Mafalda Cacciottolo, Alejandro Martin-Montalvo, Rafael de Cabo, Min Wei,[...]. Cancer Cell 2016
Stefano Di Biase, Changhan Lee, Sebastian Brandhorst, Brianna Manes, Roberta Buono, Chia-Wei Cheng, Mafalda Cacciottolo, Alejandro Martin-Montalvo, Rafael de Cabo, Min Wei,[...]. Cancer Cell 2016
6
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy.
Changhan Lee, Lizzia Raffaghello, Sebastian Brandhorst, Fernando M Safdie, Giovanna Bianchi, Alejandro Martin-Montalvo, Vito Pistoia, Min Wei, Saewon Hwang, Annalisa Merlino,[...]. Sci Transl Med 2012
Changhan Lee, Lizzia Raffaghello, Sebastian Brandhorst, Fernando M Safdie, Giovanna Bianchi, Alejandro Martin-Montalvo, Vito Pistoia, Min Wei, Saewon Hwang, Annalisa Merlino,[...]. Sci Transl Med 2012
6
Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
6
Inflamm-aging. An evolutionary perspective on immunosenescence.
C Franceschi, M Bonafè, S Valensin, F Olivieri, M De Luca, E Ottaviani, G De Benedictis. Ann N Y Acad Sci 2000
C Franceschi, M Bonafè, S Valensin, F Olivieri, M De Luca, E Ottaviani, G De Benedictis. Ann N Y Acad Sci 2000
6
Aging and survival: the genetics of life span extension by dietary restriction.
William Mair, Andrew Dillin. Annu Rev Biochem 2008
William Mair, Andrew Dillin. Annu Rev Biochem 2008
6
Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population.
Morgan E Levine, Jorge A Suarez, Sebastian Brandhorst, Priya Balasubramanian, Chia-Wei Cheng, Federica Madia, Luigi Fontana, Mario G Mirisola, Jaime Guevara-Aguirre, Junxiang Wan,[...]. Cell Metab 2014
Morgan E Levine, Jorge A Suarez, Sebastian Brandhorst, Priya Balasubramanian, Chia-Wei Cheng, Federica Madia, Luigi Fontana, Mario G Mirisola, Jaime Guevara-Aguirre, Junxiang Wan,[...]. Cell Metab 2014
6
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.
Tadahiro Shimazu, Matthew D Hirschey, John Newman, Wenjuan He, Kotaro Shirakawa, Natacha Le Moan, Carrie A Grueter, Hyungwook Lim, Laura R Saunders, Robert D Stevens,[...]. Science 2013
Tadahiro Shimazu, Matthew D Hirschey, John Newman, Wenjuan He, Kotaro Shirakawa, Natacha Le Moan, Carrie A Grueter, Hyungwook Lim, Laura R Saunders, Robert D Stevens,[...]. Science 2013
6
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.
Matt Kaeberlein, R Wilson Powers, Kristan K Steffen, Eric A Westman, Di Hu, Nick Dang, Emily O Kerr, Kathryn T Kirkland, Stanley Fields, Brian K Kennedy. Science 2005
Matt Kaeberlein, R Wilson Powers, Kristan K Steffen, Eric A Westman, Di Hu, Nick Dang, Emily O Kerr, Kathryn T Kirkland, Stanley Fields, Brian K Kennedy. Science 2005
6
Extended longevity in mice lacking the insulin receptor in adipose tissue.
Matthias Blüher, Barbara B Kahn, C Ronald Kahn. Science 2003
Matthias Blüher, Barbara B Kahn, C Ronald Kahn. Science 2003
6
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein.
D J Clancy, D Gems, L G Harshman, S Oldham, H Stocker, E Hafen, S J Leevers, L Partridge. Science 2001
D J Clancy, D Gems, L G Harshman, S Oldham, H Stocker, E Hafen, S J Leevers, L Partridge. Science 2001
6
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans.
Eric L Greer, Anne Brunet. Aging Cell 2009
Eric L Greer, Anne Brunet. Aging Cell 2009
6
Calorie restriction in humans: An update.
Jasper Most, Valeria Tosti, Leanne M Redman, Luigi Fontana. Ageing Res Rev 2017
Jasper Most, Valeria Tosti, Leanne M Redman, Luigi Fontana. Ageing Res Rev 2017
6
Cellular senescence: when bad things happen to good cells.
Judith Campisi, Fabrizio d'Adda di Fagagna. Nat Rev Mol Cell Biol 2007
Judith Campisi, Fabrizio d'Adda di Fagagna. Nat Rev Mol Cell Biol 2007
5
The essence of senescence.
Thomas Kuilman, Chrysiis Michaloglou, Wolter J Mooi, Daniel S Peeper. Genes Dev 2010
Thomas Kuilman, Chrysiis Michaloglou, Wolter J Mooi, Daniel S Peeper. Genes Dev 2010
5
Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
Filipe Cabreiro, Catherine Au, Kit-Yi Leung, Nuria Vergara-Irigaray, Helena M Cochemé, Tahereh Noori, David Weinkove, Eugene Schuster, Nicholas D E Greene, David Gems. Cell 2013
Filipe Cabreiro, Catherine Au, Kit-Yi Leung, Nuria Vergara-Irigaray, Helena M Cochemé, Tahereh Noori, David Weinkove, Eugene Schuster, Nicholas D E Greene, David Gems. Cell 2013
5
A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity.
Eric Ravussin, Leanne M Redman, James Rochon, Sai Krupa Das, Luigi Fontana, William E Kraus, Sergei Romashkan, Donald A Williamson, Simin N Meydani, Dennis T Villareal,[...]. J Gerontol A Biol Sci Med Sci 2015
Eric Ravussin, Leanne M Redman, James Rochon, Sai Krupa Das, Luigi Fontana, William E Kraus, Sergei Romashkan, Donald A Williamson, Simin N Meydani, Dennis T Villareal,[...]. J Gerontol A Biol Sci Med Sci 2015
5
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