Peter Duewell, Hajime Kono, Katey J Rayner, Cherilyn M Sirois, Gregory Vladimer, Franz G Bauernfeind, George S Abela, Luigi Franchi, Gabriel Nuñez, Max Schnurr, Terje Espevik, Egil Lien, Katherine A Fitzgerald, Kenneth L Rock, Kathryn J Moore, Samuel D Wright, Veit Hornung, Eicke Latz. Nature 2010
Times Cited: 2307
Times Cited: 2307
Times Cited
Times Co-cited
Similarity
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.
Paul M Ridker, Brendan M Everett, Tom Thuren, Jean G MacFadyen, William H Chang, Christie Ballantyne, Francisco Fonseca, Jose Nicolau, Wolfgang Koenig, Stefan D Anker,[...]. N Engl J Med 2017
Paul M Ridker, Brendan M Everett, Tom Thuren, Jean G MacFadyen, William H Chang, Christie Ballantyne, Francisco Fonseca, Jose Nicolau, Wolfgang Koenig, Stefan D Anker,[...]. N Engl J Med 2017
40
Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction.
Jean-Claude Tardif, Simon Kouz, David D Waters, Olivier F Bertrand, Rafael Diaz, Aldo P Maggioni, Fausto J Pinto, Reda Ibrahim, Habib Gamra, Ghassan S Kiwan,[...]. N Engl J Med 2019
Jean-Claude Tardif, Simon Kouz, David D Waters, Olivier F Bertrand, Rafael Diaz, Aldo P Maggioni, Fausto J Pinto, Reda Ibrahim, Habib Gamra, Ghassan S Kiwan,[...]. N Engl J Med 2019
23
Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation.
Kristiina Rajamäki, Jani Lappalainen, Katariina Oörni, Elina Välimäki, Sampsa Matikainen, Petri T Kovanen, Kari K Eklund. PLoS One 2010
Kristiina Rajamäki, Jani Lappalainen, Katariina Oörni, Elina Välimäki, Sampsa Matikainen, Petri T Kovanen, Kari K Eklund. PLoS One 2010
21
Colchicine in Patients with Chronic Coronary Disease.
Stefan M Nidorf, Aernoud T L Fiolet, Arend Mosterd, John W Eikelboom, Astrid Schut, Tjerk S J Opstal, Salem H K The, Xiao-Fang Xu, Mark A Ireland, Timo Lenderink,[...]. N Engl J Med 2020
Stefan M Nidorf, Aernoud T L Fiolet, Arend Mosterd, John W Eikelboom, Astrid Schut, Tjerk S J Opstal, Salem H K The, Xiao-Fang Xu, Mark A Ireland, Timo Lenderink,[...]. N Engl J Med 2020
19
Gout-associated uric acid crystals activate the NALP3 inflammasome.
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
16
Low-dose colchicine for secondary prevention of cardiovascular disease.
Stefan M Nidorf, John W Eikelboom, Charley A Budgeon, Peter L Thompson. J Am Coll Cardiol 2013
Stefan M Nidorf, John W Eikelboom, Charley A Budgeon, Peter L Thompson. J Am Coll Cardiol 2013
14
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
14
NLRP3 Inflammasome and the IL-1 Pathway in Atherosclerosis.
Alena Grebe, Florian Hoss, Eicke Latz. Circ Res 2018
Alena Grebe, Florian Hoss, Eicke Latz. Circ Res 2018
13
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
13
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
12
NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E-Deficient Mice-Brief Report.
Thomas van der Heijden, Eva Kritikou, Wouter Venema, Janine van Duijn, Peter J van Santbrink, Bram Slütter, Amanda C Foks, Ilze Bot, Johan Kuiper. Arterioscler Thromb Vasc Biol 2017
Thomas van der Heijden, Eva Kritikou, Wouter Venema, Janine van Duijn, Peter J van Santbrink, Bram Slütter, Amanda C Foks, Ilze Bot, Johan Kuiper. Arterioscler Thromb Vasc Biol 2017
11
A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
11
The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
11
Colchicine--Update on mechanisms of action and therapeutic uses.
Ying Ying Leung, Laura Li Yao Hui, Virginia B Kraus. Semin Arthritis Rheum 2015
Ying Ying Leung, Laura Li Yao Hui, Virginia B Kraus. Semin Arthritis Rheum 2015
10
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta.
Fabio Martinon, Kimberly Burns, Jürg Tschopp. Mol Cell 2002
Fabio Martinon, Kimberly Burns, Jürg Tschopp. Mol Cell 2002
10
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
10
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Frederick J Sheedy, Alena Grebe, Katey J Rayner, Parisa Kalantari, Bhama Ramkhelawon, Susan B Carpenter, Christine E Becker, Hasini N Ediriweera, Adam E Mullick, Douglas T Golenbock,[...]. Nat Immunol 2013
Frederick J Sheedy, Alena Grebe, Katey J Rayner, Parisa Kalantari, Bhama Ramkhelawon, Susan B Carpenter, Christine E Becker, Hasini N Ediriweera, Adam E Mullick, Douglas T Golenbock,[...]. Nat Immunol 2013
9
Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities.
Magnus Bäck, Arif Yurdagul, Ira Tabas, Katariina Öörni, Petri T Kovanen. Nat Rev Cardiol 2019
Magnus Bäck, Arif Yurdagul, Ira Tabas, Katariina Öörni, Petri T Kovanen. Nat Rev Cardiol 2019
9
Low-Dose Methotrexate for the Prevention of Atherosclerotic Events.
Paul M Ridker, Brendan M Everett, Aruna Pradhan, Jean G MacFadyen, Daniel H Solomon, Elaine Zaharris, Virak Mam, Ahmed Hasan, Yves Rosenberg, Erin Iturriaga,[...]. N Engl J Med 2019
Paul M Ridker, Brendan M Everett, Aruna Pradhan, Jean G MacFadyen, Daniel H Solomon, Elaine Zaharris, Virak Mam, Ahmed Hasan, Yves Rosenberg, Erin Iturriaga,[...]. N Engl J Med 2019
8
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
8
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Veit Hornung, Franz Bauernfeind, Annett Halle, Eivind O Samstad, Hajime Kono, Kenneth L Rock, Katherine A Fitzgerald, Eicke Latz. Nat Immunol 2008
Veit Hornung, Franz Bauernfeind, Annett Halle, Eivind O Samstad, Hajime Kono, Kenneth L Rock, Katherine A Fitzgerald, Eicke Latz. Nat Immunol 2008
8
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.
Cameron R Stewart, Lynda M Stuart, Kim Wilkinson, Janine M van Gils, Jiusheng Deng, Annett Halle, Katey J Rayner, Laurent Boyer, Ruiqin Zhong, William A Frazier,[...]. Nat Immunol 2010
Cameron R Stewart, Lynda M Stuart, Kim Wilkinson, Janine M van Gils, Jiusheng Deng, Annett Halle, Katey J Rayner, Laurent Boyer, Ruiqin Zhong, William A Frazier,[...]. Nat Immunol 2010
8
Effect of Losmapimod on Cardiovascular Outcomes in Patients Hospitalized With Acute Myocardial Infarction: A Randomized Clinical Trial.
Michelle L O'Donoghue, Ruchira Glaser, Matthew A Cavender, Philip E Aylward, Marc P Bonaca, Andrzej Budaj, Richard Y Davies, Mikael Dellborg, Keith A A Fox, Jorge Antonio T Gutierrez,[...]. JAMA 2016
Michelle L O'Donoghue, Ruchira Glaser, Matthew A Cavender, Philip E Aylward, Marc P Bonaca, Andrzej Budaj, Richard Y Davies, Mikael Dellborg, Keith A A Fox, Jorge Antonio T Gutierrez,[...]. JAMA 2016
7
Mechanism and Regulation of NLRP3 Inflammasome Activation.
Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
7
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.
Nathan Kelley, Devon Jeltema, Yanhui Duan, Yuan He. Int J Mol Sci 2019
Nathan Kelley, Devon Jeltema, Yanhui Duan, Yuan He. Int J Mol Sci 2019
7
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
Jun Jacob Hu, Xing Liu, Shiyu Xia, Zhibin Zhang, Ying Zhang, Jingxia Zhao, Jianbin Ruan, Xuemei Luo, Xiwen Lou, Yang Bai,[...]. Nat Immunol 2020
Jun Jacob Hu, Xing Liu, Shiyu Xia, Zhibin Zhang, Ying Zhang, Jingxia Zhao, Jianbin Ruan, Xuemei Luo, Xiwen Lou, Yang Bai,[...]. Nat Immunol 2020
7
Non-canonical inflammasome activation targets caspase-11.
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
7
Vascular smooth muscle cells in atherosclerosis.
Gemma L Basatemur, Helle F Jørgensen, Murray C H Clarke, Martin R Bennett, Ziad Mallat. Nat Rev Cardiol 2019
Gemma L Basatemur, Helle F Jørgensen, Murray C H Clarke, Martin R Bennett, Ziad Mallat. Nat Rev Cardiol 2019
7
Inflammasomes: mechanism of action, role in disease, and therapeutics.
Haitao Guo, Justin B Callaway, Jenny P-Y Ting. Nat Med 2015
Haitao Guo, Justin B Callaway, Jenny P-Y Ting. Nat Med 2015
7
Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia.
Deepak L Bhatt, P Gabriel Steg, Michael Miller, Eliot A Brinton, Terry A Jacobson, Steven B Ketchum, Ralph T Doyle, Rebecca A Juliano, Lixia Jiao, Craig Granowitz,[...]. N Engl J Med 2019
Deepak L Bhatt, P Gabriel Steg, Michael Miller, Eliot A Brinton, Terry A Jacobson, Steven B Ketchum, Ralph T Doyle, Rebecca A Juliano, Lixia Jiao, Craig Granowitz,[...]. N Engl J Med 2019
7
NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?
Jurg Tschopp, Kate Schroder. Nat Rev Immunol 2010
Jurg Tschopp, Kate Schroder. Nat Rev Immunol 2010
6
Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice.
Vinay Bhaskar, Johnny Yin, Amer M Mirza, Dan Phan, Sandra Vanegas, Hassan Issafras, Kristen Michelson, John J Hunter, Seema S Kantak. Atherosclerosis 2011
Vinay Bhaskar, Johnny Yin, Amer M Mirza, Dan Phan, Sandra Vanegas, Hassan Issafras, Kristen Michelson, John J Hunter, Seema S Kantak. Atherosclerosis 2011
6
Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.
Siddhartha Jaiswal, Pradeep Natarajan, Alexander J Silver, Christopher J Gibson, Alexander G Bick, Eugenia Shvartz, Marie McConkey, Namrata Gupta, Stacey Gabriel, Diego Ardissino,[...]. N Engl J Med 2017
Siddhartha Jaiswal, Pradeep Natarajan, Alexander J Silver, Christopher J Gibson, Alexander G Bick, Eugenia Shvartz, Marie McConkey, Namrata Gupta, Stacey Gabriel, Diego Ardissino,[...]. N Engl J Med 2017
6
C-reactive protein levels and outcomes after statin therapy.
Paul M Ridker, Christopher P Cannon, David Morrow, Nader Rifai, Lynda M Rose, Carolyn H McCabe, Marc A Pfeffer, Eugene Braunwald. N Engl J Med 2005
Paul M Ridker, Christopher P Cannon, David Morrow, Nader Rifai, Lynda M Rose, Carolyn H McCabe, Marc A Pfeffer, Eugene Braunwald. N Engl J Med 2005
6
Colchicine Therapy and Plaque Stabilization in Patients With Acute Coronary Syndrome: A CT Coronary Angiography Study.
Kaivan Vaidya, Clare Arnott, Gonzalo J Martínez, Bernard Ng, Samuel McCormack, David R Sullivan, David S Celermajer, Sanjay Patel. JACC Cardiovasc Imaging 2018
Kaivan Vaidya, Clare Arnott, Gonzalo J Martínez, Bernard Ng, Samuel McCormack, David R Sullivan, David S Celermajer, Sanjay Patel. JACC Cardiovasc Imaging 2018
6
6
Cholesterol crystal induced arterial inflammation and destabilization of atherosclerotic plaque.
Abed Janoudi, Fadi E Shamoun, Jagadeesh K Kalavakunta, George S Abela. Eur Heart J 2016
Abed Janoudi, Fadi E Shamoun, Jagadeesh K Kalavakunta, George S Abela. Eur Heart J 2016
6
6
Lack of interleukin-1beta decreases the severity of atherosclerosis in ApoE-deficient mice.
Hirokazu Kirii, Tamikazu Niwa, Yasuhiro Yamada, Hisayasu Wada, Kuniaki Saito, Yoichiro Iwakura, Masahide Asano, Hisataka Moriwaki, Mitsuru Seishima. Arterioscler Thromb Vasc Biol 2003
Hirokazu Kirii, Tamikazu Niwa, Yasuhiro Yamada, Hisayasu Wada, Kuniaki Saito, Yoichiro Iwakura, Masahide Asano, Hisataka Moriwaki, Mitsuru Seishima. Arterioscler Thromb Vasc Biol 2003
6
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance.
Bolormaa Vandanmagsar, Yun-Hee Youm, Anthony Ravussin, Jose E Galgani, Krisztian Stadler, Randall L Mynatt, Eric Ravussin, Jacqueline M Stephens, Vishwa Deep Dixit. Nat Med 2011
Bolormaa Vandanmagsar, Yun-Hee Youm, Anthony Ravussin, Jose E Galgani, Krisztian Stadler, Randall L Mynatt, Eric Ravussin, Jacqueline M Stephens, Vishwa Deep Dixit. Nat Med 2011
6
Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders.
Hua Jiang, Hongbin He, Yun Chen, Wei Huang, Jinbo Cheng, Jin Ye, Aoli Wang, Jinhui Tao, Chao Wang, Qingsong Liu,[...]. J Exp Med 2017
Hua Jiang, Hongbin He, Yun Chen, Wei Huang, Jinbo Cheng, Jin Ye, Aoli Wang, Jinhui Tao, Chao Wang, Qingsong Liu,[...]. J Exp Med 2017
6
Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
Anette Christ, Patrick Günther, Mario A R Lauterbach, Peter Duewell, Debjani Biswas, Karin Pelka, Claus J Scholz, Marije Oosting, Kristian Haendler, Kevin Baßler,[...]. Cell 2018
Anette Christ, Patrick Günther, Mario A R Lauterbach, Peter Duewell, Debjani Biswas, Karin Pelka, Claus J Scholz, Marije Oosting, Kristian Haendler, Kevin Baßler,[...]. Cell 2018
6
Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.
Yi Huang, Hua Jiang, Yun Chen, Xiaqiong Wang, Yanqing Yang, Jinhui Tao, Xianming Deng, Gaolin Liang, Huafeng Zhang, Wei Jiang,[...]. EMBO Mol Med 2018
Yi Huang, Hua Jiang, Yun Chen, Xiaqiong Wang, Yanqing Yang, Jinhui Tao, Xianming Deng, Gaolin Liang, Huafeng Zhang, Wei Jiang,[...]. EMBO Mol Med 2018
6
Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis.
Amélie Vromman, Victoria Ruvkun, Eugenia Shvartz, Gregory Wojtkiewicz, Gustavo Santos Masson, Yevgenia Tesmenitsky, Eduardo Folco, Hermann Gram, Matthias Nahrendorf, Filip K Swirski,[...]. Eur Heart J 2019
Amélie Vromman, Victoria Ruvkun, Eugenia Shvartz, Gregory Wojtkiewicz, Gustavo Santos Masson, Yevgenia Tesmenitsky, Eduardo Folco, Hermann Gram, Matthias Nahrendorf, Filip K Swirski,[...]. Eur Heart J 2019
10
Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice.
Christophe Combadière, Stéphane Potteaux, Mathieu Rodero, Tabassome Simon, Adeline Pezard, Bruno Esposito, Régine Merval, Amanda Proudfoot, Alain Tedgui, Ziad Mallat. Circulation 2008
Christophe Combadière, Stéphane Potteaux, Mathieu Rodero, Tabassome Simon, Adeline Pezard, Bruno Esposito, Régine Merval, Amanda Proudfoot, Alain Tedgui, Ziad Mallat. Circulation 2008
6
T cell subsets and functions in atherosclerosis.
Ryosuke Saigusa, Holger Winkels, Klaus Ley. Nat Rev Cardiol 2020
Ryosuke Saigusa, Holger Winkels, Klaus Ley. Nat Rev Cardiol 2020
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.