Maria Manczak, Peizhong Mao, Marcus J Calkins, Anda Cornea, Arubala P Reddy, Michael P Murphy, Hazel H Szeto, Byung Park, P Hemachandra Reddy. J Alzheimers Dis 2010
Times Cited: 328
Times Cited: 328
Times Cited
Times Co-cited
Similarity
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
30
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease.
Marcus J Calkins, Maria Manczak, Peizhong Mao, Ulziibat Shirendeb, P Hemachandra Reddy. Hum Mol Genet 2011
Marcus J Calkins, Maria Manczak, Peizhong Mao, Ulziibat Shirendeb, P Hemachandra Reddy. Hum Mol Genet 2011
29
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins.
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
28
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
21
Synergistic Protective Effects of Mitochondrial Division Inhibitor 1 and Mitochondria-Targeted Small Peptide SS31 in Alzheimer's Disease.
P Hemachandra Reddy, Maria Manczak, XiangLing Yin, Arubala P Reddy. J Alzheimers Dis 2018
P Hemachandra Reddy, Maria Manczak, XiangLing Yin, Arubala P Reddy. J Alzheimers Dis 2018
46
Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury.
Kesheng Zhao, Guo-Min Zhao, Dunli Wu, Yi Soong, Alex V Birk, Peter W Schiller, Hazel H Szeto. J Biol Chem 2004
Kesheng Zhao, Guo-Min Zhao, Dunli Wu, Yi Soong, Alex V Birk, Peter W Schiller, Hazel H Szeto. J Biol Chem 2004
17
Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model.
Heng Du, Lan Guo, Shiqiang Yan, Alexander A Sosunov, Guy M McKhann, Shirley ShiDu Yan. Proc Natl Acad Sci U S A 2010
Heng Du, Lan Guo, Shiqiang Yan, Alexander A Sosunov, Guy M McKhann, Shirley ShiDu Yan. Proc Natl Acad Sci U S A 2010
16
Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
16
The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease.
Meagan J McManus, Michael P Murphy, James L Franklin. J Neurosci 2011
Meagan J McManus, Michael P Murphy, James L Franklin. J Neurosci 2011
16
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Joyce W Lustbader, Maurizio Cirilli, Chang Lin, Hong Wei Xu, Kazuhiro Takuma, Ning Wang, Casper Caspersen, Xi Chen, Susan Pollak, Michael Chaney,[...]. Science 2004
Joyce W Lustbader, Maurizio Cirilli, Chang Lin, Hong Wei Xu, Kazuhiro Takuma, Ning Wang, Casper Caspersen, Xi Chen, Susan Pollak, Michael Chaney,[...]. Science 2004
15
Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases.
P Hemachandra Reddy, Tejaswini P Reddy, Maria Manczak, Marcus J Calkins, Ulziibat Shirendeb, Peizhong Mao. Brain Res Rev 2011
P Hemachandra Reddy, Tejaswini P Reddy, Maria Manczak, Marcus J Calkins, Ulziibat Shirendeb, Peizhong Mao. Brain Res Rev 2011
15
Mitochondrial oxidative damage in aging and Alzheimer's disease: implications for mitochondrially targeted antioxidant therapeutics.
P Hemachandra Reddy. J Biomed Biotechnol 2006
P Hemachandra Reddy. J Biomed Biotechnol 2006
15
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
15
A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity.
Xin Qi, Nir Qvit, Yu-Chin Su, Daria Mochly-Rosen. J Cell Sci 2013
Xin Qi, Nir Qvit, Yu-Chin Su, Daria Mochly-Rosen. J Cell Sci 2013
13
Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties.
G F Kelso, C M Porteous, C V Coulter, G Hughes, W K Porteous, E C Ledgerwood, R A Smith, M P Murphy. J Biol Chem 2001
G F Kelso, C M Porteous, C V Coulter, G Hughes, W K Porteous, E C Ledgerwood, R A Smith, M P Murphy. J Biol Chem 2001
13
Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics.
P Hemachandra Reddy, Raghav Tripathi, Quang Troung, Karuna Tirumala, Tejaswini P Reddy, Vishwanath Anekonda, Ulziibat P Shirendeb, Marcus J Calkins, Arubala P Reddy, Peizhong Mao,[...]. Biochim Biophys Acta 2012
P Hemachandra Reddy, Raghav Tripathi, Quang Troung, Karuna Tirumala, Tejaswini P Reddy, Vishwanath Anekonda, Ulziibat P Shirendeb, Marcus J Calkins, Arubala P Reddy, Peizhong Mao,[...]. Biochim Biophys Acta 2012
13
Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Maria Manczak, Ramesh Kandimalla, David Fry, Hiromi Sesaki, P Hemachandra Reddy. Hum Mol Genet 2016
Maria Manczak, Ramesh Kandimalla, David Fry, Hiromi Sesaki, P Hemachandra Reddy. Hum Mol Genet 2016
13
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression.
Maria Manczak, Thimmappa S Anekonda, Edward Henson, Byung S Park, Joseph Quinn, P Hemachandra Reddy. Hum Mol Genet 2006
Maria Manczak, Thimmappa S Anekonda, Edward Henson, Byung S Park, Joseph Quinn, P Hemachandra Reddy. Hum Mol Genet 2006
13
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.
Latha Devi, Badanavalu M Prabhu, Domenico F Galati, Narayan G Avadhani, Hindupur K Anandatheerthavarada. J Neurosci 2006
Latha Devi, Badanavalu M Prabhu, Domenico F Galati, Narayan G Avadhani, Hindupur K Anandatheerthavarada. J Neurosci 2006
13
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease.
P Hemachandra Reddy, M Flint Beal. Trends Mol Med 2008
P Hemachandra Reddy, M Flint Beal. Trends Mol Med 2008
13
Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer's disease.
P Hemachandra Reddy, Maria Manczak, Ramesh Kandimalla. Hum Mol Genet 2017
P Hemachandra Reddy, Maria Manczak, Ramesh Kandimalla. Hum Mol Genet 2017
29
Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
Maria Manczak, Ramesh Kandimalla, Xiangling Yin, P Hemachandra Reddy. Hum Mol Genet 2018
Maria Manczak, Ramesh Kandimalla, Xiangling Yin, P Hemachandra Reddy. Hum Mol Genet 2018
13
Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease.
Xiangling Yin, Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2016
Xiangling Yin, Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2016
18
Mitochondrial medicine for aging and neurodegenerative diseases.
P Hemachandra Reddy. Neuromolecular Med 2008
P Hemachandra Reddy. Neuromolecular Med 2008
13
Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis.
Susanne Petri, Mahmoud Kiaei, Maria Damiano, Andrew Hiller, Elizabeth Wille, Giovanni Manfredi, Noel Y Calingasan, Hazel H Szeto, M Flint Beal. J Neurochem 2006
Susanne Petri, Mahmoud Kiaei, Maria Damiano, Andrew Hiller, Elizabeth Wille, Giovanni Manfredi, Noel Y Calingasan, Hazel H Szeto, M Flint Beal. J Neurochem 2006
12
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae.
Camilla A Hansson Petersen, Nyosha Alikhani, Homira Behbahani, Birgitta Wiehager, Pavel F Pavlov, Irina Alafuzoff, Ville Leinonen, Akira Ito, Bengt Winblad, Elzbieta Glaser,[...]. Proc Natl Acad Sci U S A 2008
Camilla A Hansson Petersen, Nyosha Alikhani, Homira Behbahani, Birgitta Wiehager, Pavel F Pavlov, Irina Alafuzoff, Ville Leinonen, Akira Ito, Bengt Winblad, Elzbieta Glaser,[...]. Proc Natl Acad Sci U S A 2008
12
Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease.
Casper Caspersen, Ning Wang, Jun Yao, Alexander Sosunov, Xi Chen, Joyce W Lustbader, Hong Wei Xu, David Stern, Guy McKhann, Shi Du Yan. FASEB J 2005
Casper Caspersen, Ning Wang, Jun Yao, Alexander Sosunov, Xi Chen, Joyce W Lustbader, Hong Wei Xu, David Stern, Guy McKhann, Shi Du Yan. FASEB J 2005
12
The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives.
Russell H Swerdlow, Jeffrey M Burns, Shaharyar M Khan. Biochim Biophys Acta 2014
Russell H Swerdlow, Jeffrey M Burns, Shaharyar M Khan. Biochim Biophys Acta 2014
12
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization.
Ann Cassidy-Stone, Jerry E Chipuk, Elena Ingerman, Cheng Song, Choong Yoo, Tomomi Kuwana, Mark J Kurth, Jared T Shaw, Jenny E Hinshaw, Douglas R Green,[...]. Dev Cell 2008
Ann Cassidy-Stone, Jerry E Chipuk, Elena Ingerman, Cheng Song, Choong Yoo, Tomomi Kuwana, Mark J Kurth, Jared T Shaw, Jenny E Hinshaw, Douglas R Green,[...]. Dev Cell 2008
11
Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model.
Wenzhang Wang, Jun Yin, Xiaopin Ma, Fanpeng Zhao, Sandra L Siedlak, Zhenlian Wang, Sandy Torres, Hisashi Fujioka, Ying Xu, George Perry,[...]. Hum Mol Genet 2017
Wenzhang Wang, Jun Yin, Xiaopin Ma, Fanpeng Zhao, Sandra L Siedlak, Zhenlian Wang, Sandy Torres, Hisashi Fujioka, Ying Xu, George Perry,[...]. Hum Mol Genet 2017
15
Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons.
Marcus J Calkins, P Hemachandra Reddy. Biochim Biophys Acta 2011
Marcus J Calkins, P Hemachandra Reddy. Biochim Biophys Acta 2011
11
Mitochondria-Division Inhibitor 1 Protects Against Amyloid-β induced Mitochondrial Fragmentation and Synaptic Damage in Alzheimer's Disease.
P Hemachandra Reddy, Maria Manczak, XiangLing Yin. J Alzheimers Dis 2017
P Hemachandra Reddy, Maria Manczak, XiangLing Yin. J Alzheimers Dis 2017
19
Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.
P Hemachandra Reddy, XiangLing Yin, Maria Manczak, Subodh Kumar, Jangampalli Adi Pradeepkiran, Murali Vijayan, Arubala P Reddy. Hum Mol Genet 2018
P Hemachandra Reddy, XiangLing Yin, Maria Manczak, Subodh Kumar, Jangampalli Adi Pradeepkiran, Murali Vijayan, Arubala P Reddy. Hum Mol Genet 2018
11
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases.
Michael T Lin, M Flint Beal. Nature 2006
Michael T Lin, M Flint Beal. Nature 2006
11
Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
Ramesh Kandimalla, Maria Manczak, Xiangling Yin, Rui Wang, P Hemachandra Reddy. Hum Mol Genet 2018
Ramesh Kandimalla, Maria Manczak, Xiangling Yin, Rui Wang, P Hemachandra Reddy. Hum Mol Genet 2018
11
Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms.
Jesse S Kerr, Bryan A Adriaanse, Nigel H Greig, Mark P Mattson, M Zameel Cader, Vilhelm A Bohr, Evandro F Fang. Trends Neurosci 2017
Jesse S Kerr, Bryan A Adriaanse, Nigel H Greig, Mark P Mattson, M Zameel Cader, Vilhelm A Bohr, Evandro F Fang. Trends Neurosci 2017
11
Aqua-soluble DDQ reduces the levels of Drp1 and Aβ and inhibits abnormal interactions between Aβ and Drp1 and protects Alzheimer's disease neurons from Aβ- and Drp1-induced mitochondrial and synaptic toxicities.
Chandra Sekhar Kuruva, Maria Manczak, Xiangling Yin, Gilbert Ogunmokun, Arubala P Reddy, P Hemachandra Reddy. Hum Mol Genet 2017
Chandra Sekhar Kuruva, Maria Manczak, Xiangling Yin, Gilbert Ogunmokun, Arubala P Reddy, P Hemachandra Reddy. Hum Mol Genet 2017
37
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
Marie Lagouge, Carmen Argmann, Zachary Gerhart-Hines, Hamid Meziane, Carles Lerin, Frederic Daussin, Nadia Messadeq, Jill Milne, Philip Lambert, Peter Elliott,[...]. Cell 2006
Marie Lagouge, Carmen Argmann, Zachary Gerhart-Hines, Hamid Meziane, Carles Lerin, Frederic Daussin, Nadia Messadeq, Jill Milne, Philip Lambert, Peter Elliott,[...]. Cell 2006
10
Targeting antioxidants to mitochondria by conjugation to lipophilic cations.
Michael P Murphy, Robin A J Smith. Annu Rev Pharmacol Toxicol 2007
Michael P Murphy, Robin A J Smith. Annu Rev Pharmacol Toxicol 2007
10
Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice.
S Hauptmann, I Scherping, S Dröse, U Brandt, K L Schulz, M Jendrach, K Leuner, A Eckert, W E Müller. Neurobiol Aging 2009
S Hauptmann, I Scherping, S Dröse, U Brandt, K L Schulz, M Jendrach, K Leuner, A Eckert, W E Müller. Neurobiol Aging 2009
10
Mitochondrial abnormalities in Alzheimer's disease.
K Hirai, G Aliev, A Nunomura, H Fujioka, R L Russell, C S Atwood, A B Johnson, Y Kress, H V Vinters, M Tabaton,[...]. J Neurosci 2001
K Hirai, G Aliev, A Nunomura, H Fujioka, R L Russell, C S Atwood, A B Johnson, Y Kress, H V Vinters, M Tabaton,[...]. J Neurosci 2001
10
Reduced dynamin-related protein 1 protects against phosphorylated Tau-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Ramesh Kandimalla, Maria Manczak, David Fry, Yeguvapalli Suneetha, Hiromi Sesaki, P Hemachandra Reddy. Hum Mol Genet 2016
Ramesh Kandimalla, Maria Manczak, David Fry, Yeguvapalli Suneetha, Hiromi Sesaki, P Hemachandra Reddy. Hum Mol Genet 2016
10
First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics.
Hazel H Szeto. Br J Pharmacol 2014
Hazel H Szeto. Br J Pharmacol 2014
10
A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease.
Barry J Snow, Fiona L Rolfe, Michelle M Lockhart, Christopher M Frampton, John D O'Sullivan, Victor Fung, Robin A J Smith, Michael P Murphy, Kenneth M Taylor. Mov Disord 2010
Barry J Snow, Fiona L Rolfe, Michelle M Lockhart, Christopher M Frampton, John D O'Sullivan, Victor Fung, Robin A J Smith, Michael P Murphy, Kenneth M Taylor. Mov Disord 2010
10
Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications.
Susana Rovira-Llopis, Celia Bañuls, Noelia Diaz-Morales, Antonio Hernandez-Mijares, Milagros Rocha, Victor M Victor. Redox Biol 2017
Susana Rovira-Llopis, Celia Bañuls, Noelia Diaz-Morales, Antonio Hernandez-Mijares, Milagros Rocha, Victor M Victor. Redox Biol 2017
9
Oxidative stress and mitochondrial dysfunction in Alzheimer's disease.
Xinglong Wang, Wenzhang Wang, Li Li, George Perry, Hyoung-gon Lee, Xiongwei Zhu. Biochim Biophys Acta 2014
Xinglong Wang, Wenzhang Wang, Li Li, George Perry, Hyoung-gon Lee, Xiongwei Zhu. Biochim Biophys Acta 2014
9
Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease.
Eugenia Trushina, Emirhan Nemutlu, Song Zhang, Trace Christensen, Jon Camp, Janny Mesa, Ammar Siddiqui, Yasushi Tamura, Hiromi Sesaki, Thomas M Wengenack,[...]. PLoS One 2012
Eugenia Trushina, Emirhan Nemutlu, Song Zhang, Trace Christensen, Jon Camp, Janny Mesa, Ammar Siddiqui, Yasushi Tamura, Hiromi Sesaki, Thomas M Wengenack,[...]. PLoS One 2012
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.