Maria Kleppe, Idoya Lahortiga, Tiama El Chaar, Kim De Keersmaecker, Nicole Mentens, Carlos Graux, Katrien Van Roosbroeck, Adolfo A Ferrando, Anton W Langerak, Jules P P Meijerink, François Sigaux, Torsten Haferlach, Iwona Wlodarska, Peter Vandenberghe, Jean Soulier, Jan Cools. Nat Genet 2010
Times Cited: 125
Times Cited: 125
Times Cited
Times Co-cited
Similarity
PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia.
Maria Kleppe, Jean Soulier, Vahid Asnafi, Nicole Mentens, Tekla Hornakova, Laurent Knoops, Stefan Constantinescu, François Sigaux, Jules P Meijerink, Peter Vandenberghe,[...]. Blood 2011
Maria Kleppe, Jean Soulier, Vahid Asnafi, Nicole Mentens, Tekla Hornakova, Laurent Knoops, Stefan Constantinescu, François Sigaux, Jules P Meijerink, Peter Vandenberghe,[...]. Blood 2011
60
Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.
Priscila P Zenatti, Daniel Ribeiro, Wenqing Li, Linda Zuurbier, Milene C Silva, Maddalena Paganin, Julia Tritapoe, Julie A Hixon, André B Silveira, Bruno A Cardoso,[...]. Nat Genet 2011
Priscila P Zenatti, Daniel Ribeiro, Wenqing Li, Linda Zuurbier, Milene C Silva, Maddalena Paganin, Julia Tritapoe, Julie A Hixon, André B Silveira, Bruno A Cardoso,[...]. Nat Genet 2011
33
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.
Jinghui Zhang, Li Ding, Linda Holmfeldt, Gang Wu, Sue L Heatley, Debbie Payne-Turner, John Easton, Xiang Chen, Jianmin Wang, Michael Rusch,[...]. Nature 2012
Jinghui Zhang, Li Ding, Linda Holmfeldt, Gang Wu, Sue L Heatley, Debbie Payne-Turner, John Easton, Xiang Chen, Jianmin Wang, Michael Rusch,[...]. Nature 2012
32
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
26
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia.
Elisabetta Flex, Valentina Petrangeli, Lorenzo Stella, Sabina Chiaretti, Tekla Hornakova, Laurent Knoops, Cristina Ariola, Valentina Fodale, Emmanuelle Clappier, Francesca Paoloni,[...]. J Exp Med 2008
Elisabetta Flex, Valentina Petrangeli, Lorenzo Stella, Sabina Chiaretti, Tekla Hornakova, Laurent Knoops, Cristina Ariola, Valentina Fodale, Emmanuelle Clappier, Francesca Paoloni,[...]. J Exp Med 2008
24
Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias.
Chen Shochat, Noa Tal, Obul R Bandapalli, Chiara Palmi, Ithamar Ganmore, Geertruy te Kronnie, Gunnar Cario, Giovanni Cazzaniga, Andreas E Kulozik, Martin Stanulla,[...]. J Exp Med 2011
Chen Shochat, Noa Tal, Obul R Bandapalli, Chiara Palmi, Ithamar Ganmore, Geertruy te Kronnie, Gunnar Cario, Giovanni Cazzaniga, Andreas E Kulozik, Martin Stanulla,[...]. J Exp Med 2011
22
Mutation analysis of the tyrosine phosphatase PTPN2 in Hodgkin's lymphoma and T-cell non-Hodgkin's lymphoma.
Maria Kleppe, Thomas Tousseyn, Eva Geissinger, Zeynep Kalender Atak, Stein Aerts, Andreas Rosenwald, Iwona Wlodarska, Jan Cools. Haematologica 2011
Maria Kleppe, Thomas Tousseyn, Eva Geissinger, Zeynep Kalender Atak, Stein Aerts, Andreas Rosenwald, Iwona Wlodarska, Jan Cools. Haematologica 2011
47
PHF6 mutations in T-cell acute lymphoblastic leukemia.
Pieter Van Vlierberghe, Teresa Palomero, Hossein Khiabanian, Joni Van der Meulen, Mireia Castillo, Nadine Van Roy, Barbara De Moerloose, Jan Philippé, Sara González-García, María L Toribio,[...]. Nat Genet 2010
Pieter Van Vlierberghe, Teresa Palomero, Hossein Khiabanian, Joni Van der Meulen, Mireia Castillo, Nadine Van Roy, Barbara De Moerloose, Jan Philippé, Sara González-García, María L Toribio,[...]. Nat Genet 2010
20
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia.
Adolfo A Ferrando, Donna S Neuberg, Jane Staunton, Mignon L Loh, Christine Huard, Susana C Raimondi, Fred G Behm, Ching Hon Pui, James R Downing, D Gary Gilliland,[...]. Cancer Cell 2002
Adolfo A Ferrando, Donna S Neuberg, Jane Staunton, Mignon L Loh, Christine Huard, Susana C Raimondi, Fred G Behm, Ching Hon Pui, James R Downing, D Gary Gilliland,[...]. Cancer Cell 2002
20
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
Benjamin J Shields, Florian Wiede, Esteban N Gurzov, Kenneth Wee, Christine Hauser, Hong-Jian Zhu, Timothy J Molloy, Sandra A O'Toole, Roger J Daly, Robert L Sutherland,[...]. Mol Cell Biol 2013
Benjamin J Shields, Florian Wiede, Esteban N Gurzov, Kenneth Wee, Christine Hauser, Hong-Jian Zhu, Timothy J Molloy, Sandra A O'Toole, Roger J Daly, Robert L Sutherland,[...]. Mol Cell Biol 2013
33
The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3.
Paul D Simoncic, Ailsa Lee-Loy, Dwayne L Barber, Michel L Tremblay, C Jane McGlade. Curr Biol 2002
Paul D Simoncic, Ailsa Lee-Loy, Dwayne L Barber, Michel L Tremblay, C Jane McGlade. Curr Biol 2002
19
HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).
Jean Soulier, Emmanuelle Clappier, Jean-Michel Cayuela, Armelle Regnault, Marina García-Peydró, Hervé Dombret, André Baruchel, Maria-Luisa Toribio, François Sigaux. Blood 2005
Jean Soulier, Emmanuelle Clappier, Jean-Michel Cayuela, Armelle Regnault, Marina García-Peydró, Hervé Dombret, André Baruchel, Maria-Luisa Toribio, François Sigaux. Blood 2005
18
Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia.
Elaine Coustan-Smith, Charles G Mullighan, Mihaela Onciu, Frederick G Behm, Susana C Raimondi, Deqing Pei, Cheng Cheng, Xiaoping Su, Jeffrey E Rubnitz, Giuseppe Basso,[...]. Lancet Oncol 2009
Elaine Coustan-Smith, Charles G Mullighan, Mihaela Onciu, Frederick G Behm, Susana C Raimondi, Deqing Pei, Cheng Cheng, Xiaoping Su, Jeffrey E Rubnitz, Giuseppe Basso,[...]. Lancet Oncol 2009
18
Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia.
Kim De Keersmaecker, Zeynep Kalender Atak, Ning Li, Carmen Vicente, Stephanie Patchett, Tiziana Girardi, Valentina Gianfelici, Ellen Geerdens, Emmanuelle Clappier, Michaël Porcu,[...]. Nat Genet 2013
Kim De Keersmaecker, Zeynep Kalender Atak, Ning Li, Carmen Vicente, Stephanie Patchett, Tiziana Girardi, Valentina Gianfelici, Ellen Geerdens, Emmanuelle Clappier, Michaël Porcu,[...]. Nat Genet 2013
18
WT1 mutations in T-ALL.
Valeria Tosello, Marc R Mansour, Kelly Barnes, Maddalena Paganin, Maria Luisa Sulis, Sarah Jenkinson, Christopher G Allen, Rosemary E Gale, David C Linch, Teresa Palomero,[...]. Blood 2009
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17
Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.
Irene Homminga, Rob Pieters, Anton W Langerak, Johan J de Rooi, Andrew Stubbs, Monique Verstegen, Maartje Vuerhard, Jessica Buijs-Gladdines, Clarissa Kooi, Petra Klous,[...]. Cancer Cell 2011
Irene Homminga, Rob Pieters, Anton W Langerak, Johan J de Rooi, Andrew Stubbs, Monique Verstegen, Maartje Vuerhard, Jessica Buijs-Gladdines, Clarissa Kooi, Petra Klous,[...]. Cancer Cell 2011
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Identification of a nuclear Stat1 protein tyrosine phosphatase.
Johanna ten Hoeve, Maria de Jesus Ibarra-Sanchez, Yubin Fu, Wei Zhu, Michel Tremblay, Michael David, Ke Shuai. Mol Cell Biol 2002
Johanna ten Hoeve, Maria de Jesus Ibarra-Sanchez, Yubin Fu, Wei Zhu, Michel Tremblay, Michael David, Ke Shuai. Mol Cell Biol 2002
15
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
15
Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice.
K E You-Ten, E S Muise, A Itié, E Michaliszyn, J Wagner, S Jothy, W S Lapp, M L Tremblay. J Exp Med 1997
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14
T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice.
Florian Wiede, Benjamin J Shields, Sock Hui Chew, Konstantinos Kyparissoudis, Catherine van Vliet, Sandra Galic, Michel L Tremblay, Sarah M Russell, Dale I Godfrey, Tony Tiganis. J Clin Invest 2011
Florian Wiede, Benjamin J Shields, Sock Hui Chew, Konstantinos Kyparissoudis, Catherine van Vliet, Sandra Galic, Michel L Tremblay, Sarah M Russell, Dale I Godfrey, Tony Tiganis. J Clin Invest 2011
14
High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia.
Alejandro Gutierrez, Takaomi Sanda, Ruta Grebliunaite, Arkaitz Carracedo, Leonardo Salmena, Yebin Ahn, Suzanne Dahlberg, Donna Neuberg, Lisa A Moreau, Stuart S Winter,[...]. Blood 2009
Alejandro Gutierrez, Takaomi Sanda, Ruta Grebliunaite, Arkaitz Carracedo, Leonardo Salmena, Yebin Ahn, Suzanne Dahlberg, Donna Neuberg, Lisa A Moreau, Stuart S Winter,[...]. Blood 2009
14
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia.
Kathryn G Roberts, Ryan D Morin, Jinghui Zhang, Martin Hirst, Yongjun Zhao, Xiaoping Su, Shann-Ching Chen, Debbie Payne-Turner, Michelle L Churchman, Richard C Harvey,[...]. Cancer Cell 2012
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14
A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia.
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14
Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.
Gannie Tzoneva, Arianne Perez-Garcia, Zachary Carpenter, Hossein Khiabanian, Valeria Tosello, Maddalena Allegretta, Elisabeth Paietta, Janis Racevskis, Jacob M Rowe, Martin S Tallman,[...]. Nat Med 2013
Gannie Tzoneva, Arianne Perez-Garcia, Zachary Carpenter, Hossein Khiabanian, Valeria Tosello, Maddalena Allegretta, Elisabeth Paietta, Janis Racevskis, Jacob M Rowe, Martin S Tallman,[...]. Nat Med 2013
14
JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model.
Sandrine Degryse, Charles E de Bock, Luk Cox, Sofie Demeyer, Olga Gielen, Nicole Mentens, Kris Jacobs, Ellen Geerdens, Valentina Gianfelici, Gert Hulselmans,[...]. Blood 2014
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14
Mutation of the receptor tyrosine phosphatase PTPRC (CD45) in T-cell acute lymphoblastic leukemia.
Michaël Porcu, Maria Kleppe, Valentina Gianfelici, Ellen Geerdens, Kim De Keersmaecker, Marco Tartaglia, Robin Foà, Jean Soulier, Barbara Cauwelier, Anne Uyttebroeck,[...]. Blood 2012
Michaël Porcu, Maria Kleppe, Valentina Gianfelici, Ellen Geerdens, Kim De Keersmaecker, Marco Tartaglia, Robin Foà, Jean Soulier, Barbara Cauwelier, Anne Uyttebroeck,[...]. Blood 2012
18
The molecular basis of T cell acute lymphoblastic leukemia.
Pieter Van Vlierberghe, Adolfo Ferrando. J Clin Invest 2012
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13
Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia.
Carmen Vicente, Claire Schwab, Michaël Broux, Ellen Geerdens, Sandrine Degryse, Sofie Demeyer, Idoya Lahortiga, Alannah Elliott, Lucy Chilton, Roberta La Starza,[...]. Haematologica 2015
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13
The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia.
Yu Liu, John Easton, Ying Shao, Jamie Maciaszek, Zhaoming Wang, Mark R Wilkinson, Kelly McCastlain, Michael Edmonson, Stanley B Pounds, Lei Shi,[...]. Nat Genet 2017
Yu Liu, John Easton, Ying Shao, Jamie Maciaszek, Zhaoming Wang, Mark R Wilkinson, Kelly McCastlain, Michael Edmonson, Stanley B Pounds, Lei Shi,[...]. Nat Genet 2017
13
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target.
Robert T Manguso, Hans W Pope, Margaret D Zimmer, Flavian D Brown, Kathleen B Yates, Brian C Miller, Natalie B Collins, Kevin Bi, Martin W LaFleur, Vikram R Juneja,[...]. Nature 2017
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13
Inside the human cancer tyrosine phosphatome.
Sofi G Julien, Nadia Dubé, Serge Hardy, Michel L Tremblay. Nat Rev Cancer 2011
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Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia.
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12
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.
D E Cool, N K Tonks, H Charbonneau, K A Walsh, E H Fischer, E G Krebs. Proc Natl Acad Sci U S A 1989
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12
Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia.
Panagiotis Ntziachristos, Aristotelis Tsirigos, Pieter Van Vlierberghe, Jelena Nedjic, Thomas Trimarchi, Maria Sol Flaherty, Dolors Ferres-Marco, Vanina da Ros, Zuojian Tang, Jasmin Siegle,[...]. Nat Med 2012
Panagiotis Ntziachristos, Aristotelis Tsirigos, Pieter Van Vlierberghe, Jelena Nedjic, Thomas Trimarchi, Maria Sol Flaherty, Dolors Ferres-Marco, Vanina da Ros, Zuojian Tang, Jasmin Siegle,[...]. Nat Med 2012
12
Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers.
Eun Goo Jeong, Min Sung Kim, Hyo Kyung Nam, Chang Ki Min, Seok Lee, Yeun Jun Chung, Nam Jin Yoo, Sug Hyung Lee. Clin Cancer Res 2008
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12
Newly described activating JAK3 mutations in T-cell acute lymphoblastic leukemia.
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A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.
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11
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
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11
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.
Charles G Mullighan, Salil Goorha, Ina Radtke, Christopher B Miller, Elaine Coustan-Smith, James D Dalton, Kevin Girtman, Susan Mathew, Jing Ma, Stanley B Pounds,[...]. Nature 2007
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Cloning and characterization of a mouse cDNA encoding a cytoplasmic protein-tyrosine-phosphatase.
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11
ETV6 mutations in early immature human T cell leukemias.
Pieter Van Vlierberghe, Alberto Ambesi-Impiombato, Arianne Perez-Garcia, J Erika Haydu, Isaura Rigo, Michael Hadler, Valeria Tosello, Giusy Della Gatta, Elisabeth Paietta, Janis Racevskis,[...]. J Exp Med 2011
Pieter Van Vlierberghe, Alberto Ambesi-Impiombato, Arianne Perez-Garcia, J Erika Haydu, Isaura Rigo, Michael Hadler, Valeria Tosello, Giusy Della Gatta, Elisabeth Paietta, Janis Racevskis,[...]. J Exp Med 2011
11
Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia.
M Kontro, H Kuusanmäki, S Eldfors, T Burmeister, E I Andersson, O Bruserud, T H Brümmendorf, H Edgren, B T Gjertsen, M Itälä-Remes,[...]. Leukemia 2014
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15
Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia.
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11
The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse.
Obul R Bandapalli, Stephanie Schuessele, Joachim B Kunz, Tobias Rausch, Adrian M Stütz, Noa Tal, Ifat Geron, Nava Gershman, Shai Izraeli, Juliane Eilers,[...]. Haematologica 2014
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13
Protein tyrosine phosphatases in the human genome.
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Protein tyrosine phosphatases: from genes, to function, to disease.
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10
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The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia.
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10
Inactivation of LEF1 in T-cell acute lymphoblastic leukemia.
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Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase.
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10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.