Evidence for an essential deglycosylation-independent activity of PNGase in Drosophila melanogaster.
Yoko Funakoshi, Yuki Negishi, J Peter Gergen, Junichi Seino, Kumiko Ishii, William J Lennarz, Ichiro Matsuo, Yukishige Ito, Naoyuki Taniguchi, Tadashi Suzuki. PLoS One 2010
Times Cited: 30
Times Cited: 30
Times Cited
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Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway.
Gregory M Enns, Vandana Shashi, Matthew Bainbridge, Michael J Gambello, Farah R Zahir, Thomas Bast, Rebecca Crimian, Kelly Schoch, Julia Platt, Rachel Cox,[...]. Genet Med 2014
Gregory M Enns, Vandana Shashi, Matthew Bainbridge, Michael J Gambello, Farah R Zahir, Thomas Bast, Rebecca Crimian, Kelly Schoch, Julia Platt, Rachel Cox,[...]. Genet Med 2014
70
PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase.
T Suzuki, H Park, N M Hollingsworth, R Sternglanz, W J Lennarz. J Cell Biol 2000
T Suzuki, H Park, N M Hollingsworth, R Sternglanz, W J Lennarz. J Cell Biol 2000
63
Clinical application of exome sequencing in undiagnosed genetic conditions.
Anna C Need, Vandana Shashi, Yuki Hitomi, Kelly Schoch, Kevin V Shianna, Marie T McDonald, Miriam H Meisler, David B Goldstein. J Med Genet 2012
Anna C Need, Vandana Shashi, Yuki Hitomi, Kelly Schoch, Kevin V Shianna, Marie T McDonald, Miriam H Meisler, David B Goldstein. J Med Genet 2012
60
Endo-β-N-acetylglucosaminidase forms N-GlcNAc protein aggregates during ER-associated degradation in Ngly1-defective cells.
Chengcheng Huang, Yoichiro Harada, Akira Hosomi, Yuki Masahara-Negishi, Junichi Seino, Haruhiko Fujihira, Yoko Funakoshi, Takehiro Suzuki, Naoshi Dohmae, Tadashi Suzuki. Proc Natl Acad Sci U S A 2015
Chengcheng Huang, Yoichiro Harada, Akira Hosomi, Yuki Masahara-Negishi, Junichi Seino, Haruhiko Fujihira, Yoko Funakoshi, Takehiro Suzuki, Naoshi Dohmae, Tadashi Suzuki. Proc Natl Acad Sci U S A 2015
53
Prospective phenotyping of NGLY1-CDDG, the first congenital disorder of deglycosylation.
Christina Lam, Carlos Ferreira, Donna Krasnewich, Camilo Toro, Lea Latham, Wadih M Zein, Tanya Lehky, Carmen Brewer, Eva H Baker, Audrey Thurm,[...]. Genet Med 2017
Christina Lam, Carlos Ferreira, Donna Krasnewich, Camilo Toro, Lea Latham, Wadih M Zein, Tanya Lehky, Carmen Brewer, Eva H Baker, Audrey Thurm,[...]. Genet Med 2017
50
The Neurospora peptide:N-glycanase ortholog PNG1 is essential for cell polarity despite its lack of enzymatic activity.
Sabine Maerz, Yoko Funakoshi, Yuki Negishi, Tadashi Suzuki, Stephan Seiler. J Biol Chem 2010
Sabine Maerz, Yoko Funakoshi, Yuki Negishi, Tadashi Suzuki, Stephan Seiler. J Biol Chem 2010
46
The N-glycanase png-1 acts to limit axon branching during organ formation in Caenorhabditis elegans.
Nasrin Habibi-Babadi, Anna Su, Carlos E de Carvalho, Antonio Colavita. J Neurosci 2010
Nasrin Habibi-Babadi, Anna Su, Carlos E de Carvalho, Antonio Colavita. J Neurosci 2010
51
Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1.
Nicolas J Lehrbach, Gary Ruvkun. Elife 2016
Nicolas J Lehrbach, Gary Ruvkun. Elife 2016
46
NGLY1 mutation causes neuromotor impairment, intellectual disability, and neuropathy.
Ahmet Okay Caglayan, Sinan Comu, Jacob F Baranoski, Yesim Parman, Hande Kaymakçalan, Gozde Tugce Akgumus, Caner Caglar, Duygu Dolen, Emine Zeynep Erson-Omay, Akdes Serin Harmanci,[...]. Eur J Med Genet 2015
Ahmet Okay Caglayan, Sinan Comu, Jacob F Baranoski, Yesim Parman, Hande Kaymakçalan, Gozde Tugce Akgumus, Caner Caglar, Duygu Dolen, Emine Zeynep Erson-Omay, Akdes Serin Harmanci,[...]. Eur J Med Genet 2015
43
The cytoplasmic peptide:N-glycanase (NGLY1) - Structure, expression and cellular functions.
Tadashi Suzuki, Chengcheng Huang, Haruhiko Fujihira. Gene 2016
Tadashi Suzuki, Chengcheng Huang, Haruhiko Fujihira. Gene 2016
40
A role for N-glycanase in the cytosolic turnover of glycoproteins.
Christian Hirsch, Daniël Blom, Hidde L Ploegh. EMBO J 2003
Christian Hirsch, Daniël Blom, Hidde L Ploegh. EMBO J 2003
36
Cytoplasmic peptide:N-glycanase and catabolic pathway for free N-glycans in the cytosol.
Tadashi Suzuki. Semin Cell Dev Biol 2007
Tadashi Suzuki. Semin Cell Dev Biol 2007
36
The Png1-Rad23 complex regulates glycoprotein turnover.
Ikjin Kim, Jungmi Ahn, Chang Liu, Kaori Tanabe, Jennifer Apodaca, Tadashi Suzuki, Hai Rao. J Cell Biol 2006
Ikjin Kim, Jungmi Ahn, Chang Liu, Kaori Tanabe, Jennifer Apodaca, Tadashi Suzuki, Hai Rao. J Cell Biol 2006
36
A plant peptide: N-glycanase orthologue facilitates glycoprotein ER-associated degradation in yeast.
Yuki Masahara-Negishi, Akira Hosomi, Massimiliano Della Mea, Donatella Serafini-Fracassini, Tadashi Suzuki. Biochim Biophys Acta 2012
Yuki Masahara-Negishi, Akira Hosomi, Massimiliano Della Mea, Donatella Serafini-Fracassini, Tadashi Suzuki. Biochim Biophys Acta 2012
42
The cytoplasmic peptide:N-glycanase (Ngly1)-basic science encounters a human genetic disorder.
Tadashi Suzuki. J Biochem 2015
Tadashi Suzuki. J Biochem 2015
36
Lethality of mice bearing a knockout of the Ngly1-gene is partially rescued by the additional deletion of the Engase gene.
Haruhiko Fujihira, Yuki Masahara-Negishi, Masaru Tamura, Chengcheng Huang, Yoichiro Harada, Shigeharu Wakana, Daisuke Takakura, Nana Kawasaki, Naoyuki Taniguchi, Gen Kondoh,[...]. PLoS Genet 2017
Haruhiko Fujihira, Yuki Masahara-Negishi, Masaru Tamura, Chengcheng Huang, Yoichiro Harada, Shigeharu Wakana, Daisuke Takakura, Nana Kawasaki, Naoyuki Taniguchi, Gen Kondoh,[...]. PLoS Genet 2017
36
Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1.
Antonio Galeone, Seung Yeop Han, Chengcheng Huang, Akira Hosomi, Tadashi Suzuki, Hamed Jafar-Nejad. Elife 2017
Antonio Galeone, Seung Yeop Han, Chengcheng Huang, Akira Hosomi, Tadashi Suzuki, Hamed Jafar-Nejad. Elife 2017
47
Transcriptome and functional analysis in a Drosophila model of NGLY1 deficiency provides insight into therapeutic approaches.
Katie G Owings, Joshua B Lowry, Yiling Bi, Matthew Might, Clement Y Chow. Hum Mol Genet 2018
Katie G Owings, Joshua B Lowry, Yiling Bi, Matthew Might, Clement Y Chow. Hum Mol Genet 2018
36
Identification of an Htm1 (EDEM)-dependent, Mns1-independent Endoplasmic Reticulum-associated Degradation (ERAD) pathway in Saccharomyces cerevisiae: application of a novel assay for glycoprotein ERAD.
Akira Hosomi, Kaori Tanabe, Hiroto Hirayama, Ikjin Kim, Hai Rao, Tadashi Suzuki. J Biol Chem 2010
Akira Hosomi, Kaori Tanabe, Hiroto Hirayama, Ikjin Kim, Hai Rao, Tadashi Suzuki. J Biol Chem 2010
34
Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover.
Shahram Misaghi, Michael E Pacold, Daniël Blom, Hidde L Ploegh, Gregory Alan Korbel. Chem Biol 2004
Shahram Misaghi, Michael E Pacold, Daniël Blom, Hidde L Ploegh, Gregory Alan Korbel. Chem Biol 2004
33
Multi-systemic involvement in NGLY1-related disorder caused by two novel mutations.
Jennifer Heeley, Marwan Shinawi. Am J Med Genet A 2015
Jennifer Heeley, Marwan Shinawi. Am J Med Genet A 2015
33
Cytoplasmic peptide:N-glycanase (PNGase) in eukaryotic cells: occurrence, primary structure, and potential functions.
Tadashi Suzuki, Hangil Park, William J Lennarz. FASEB J 2002
Tadashi Suzuki, Hangil Park, William J Lennarz. FASEB J 2002
30
A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised.
Daniël Blom, Christian Hirsch, Patrick Stern, Domenico Tortorella, Hidde L Ploegh. EMBO J 2004
Daniël Blom, Christian Hirsch, Patrick Stern, Domenico Tortorella, Hidde L Ploegh. EMBO J 2004
30
Identification and characterization of peptide: N-glycanase from Dictyostelium discoideum.
Anuradha Gosain, Rakhee Lohia, Anju Shrivastava, Shweta Saran. BMC Biochem 2012
Anuradha Gosain, Rakhee Lohia, Anju Shrivastava, Shweta Saran. BMC Biochem 2012
34
Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity.
Frederick M Tomlin, Ulla I M Gerling-Driessen, Yi-Chang Liu, Ryan A Flynn, Janakiram R Vangala, Christian S Lentz, Sandra Clauder-Muenster, Petra Jakob, William F Mueller, Diana Ordoñez-Rueda,[...]. ACS Cent Sci 2017
Frederick M Tomlin, Ulla I M Gerling-Driessen, Yi-Chang Liu, Ryan A Flynn, Janakiram R Vangala, Christian S Lentz, Sandra Clauder-Muenster, Petra Jakob, William F Mueller, Diana Ordoñez-Rueda,[...]. ACS Cent Sci 2017
30
N-linked glycosylation does not impair proteasomal degradation but affects class I major histocompatibility complex presentation.
Edith Kario, Boaz Tirosh, Hidde L Ploegh, Ami Navon. J Biol Chem 2008
Edith Kario, Boaz Tirosh, Hidde L Ploegh, Ami Navon. J Biol Chem 2008
26
Site-directed mutagenesis study of yeast peptide:N-glycanase. Insight into the reaction mechanism of deglycosylation.
Samiksha Katiyar, Tadashi Suzuki, Bhumika J Balgobin, William J Lennarz. J Biol Chem 2002
Samiksha Katiyar, Tadashi Suzuki, Bhumika J Balgobin, William J Lennarz. J Biol Chem 2002
26
The genetic basis of cellular morphogenesis in the filamentous fungus Neurospora crassa.
Stephan Seiler, Michael Plamann. Mol Biol Cell 2003
Stephan Seiler, Michael Plamann. Mol Biol Cell 2003
26
A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins.
Samiksha Katiyar, Guangtao Li, William J Lennarz. Proc Natl Acad Sci U S A 2004
Samiksha Katiyar, Guangtao Li, William J Lennarz. Proc Natl Acad Sci U S A 2004
26
N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1.
Kun Yang, Ryan Huang, Haruhiko Fujihira, Tadashi Suzuki, Nan Yan. J Exp Med 2018
Kun Yang, Ryan Huang, Haruhiko Fujihira, Tadashi Suzuki, Nan Yan. J Exp Med 2018
26
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression.
Nicolas J Lehrbach, Peter C Breen, Gary Ruvkun. Cell 2019
Nicolas J Lehrbach, Peter C Breen, Gary Ruvkun. Cell 2019
26
A cytoplasmic peptide: N-glycanase.
Kaori Tanabe, William J Lennarz, Tadashi Suzuki. Methods Enzymol 2006
Kaori Tanabe, William J Lennarz, Tadashi Suzuki. Methods Enzymol 2006
30
Free oligosaccharides to monitor glycoprotein endoplasmic reticulum-associated degradation in Saccharomyces cerevisiae.
Hiroto Hirayama, Junichi Seino, Toshihiko Kitajima, Yoshifumi Jigami, Tadashi Suzuki. J Biol Chem 2010
Hiroto Hirayama, Junichi Seino, Toshihiko Kitajima, Yoshifumi Jigami, Tadashi Suzuki. J Biol Chem 2010
23
The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway.
T Suzuki, H Park, E A Till, W J Lennarz. Biochem Biophys Res Commun 2001
T Suzuki, H Park, E A Till, W J Lennarz. Biochem Biophys Res Commun 2001
23
Identification of peptide:N-glycanase activity in mammalian-derived cultured cells.
T Suzuki, A Seko, K Kitajima, Y Inoue, S Inoue. Biochem Biophys Res Commun 1993
T Suzuki, A Seko, K Kitajima, Y Inoue, S Inoue. Biochem Biophys Res Commun 1993
23
The Arabidopsis AtPNG1 gene encodes a peptide: N-glycanase.
Andreas Diepold, Guangtao Li, William J Lennarz, Thorsten Nürnberger, Frédéric Brunner. Plant J 2007
Andreas Diepold, Guangtao Li, William J Lennarz, Thorsten Nürnberger, Frédéric Brunner. Plant J 2007
23
Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells.
Senthil K Radhakrishnan, Candy S Lee, Patrick Young, Anne Beskow, Jefferson Y Chan, Raymond J Deshaies. Mol Cell 2010
Senthil K Radhakrishnan, Candy S Lee, Patrick Young, Anne Beskow, Jefferson Y Chan, Raymond J Deshaies. Mol Cell 2010
23
Defects in the Neuroendocrine Axis Contribute to Global Development Delay in a Drosophila Model of NGLY1 Deficiency.
Tamy Portillo Rodriguez, Joshua D Mast, Tom Hartl, Tom Lee, Peter Sand, Ethan O Perlstein. G3 (Bethesda) 2018
Tamy Portillo Rodriguez, Joshua D Mast, Tom Hartl, Tom Lee, Peter Sand, Ethan O Perlstein. G3 (Bethesda) 2018
43
Orthopaedic phenotyping of NGLY1 deficiency using an international, family-led disease registry.
Eli M Cahan, Steven L Frick. Orphanet J Rare Dis 2019
Eli M Cahan, Steven L Frick. Orphanet J Rare Dis 2019
50
Free N-linked oligosaccharide chains: formation and degradation.
Tadashi Suzuki, Yoko Funakoshi. Glycoconj J 2006
Tadashi Suzuki, Yoko Funakoshi. Glycoconj J 2006
20
Endo-beta-N-acetylglucosaminidase, an enzyme involved in processing of free oligosaccharides in the cytosol.
Tadashi Suzuki, Keiichi Yano, Seiji Sugimoto, Ken Kitajima, William J Lennarz, Sadako Inoue, Yasuo Inoue, Yasufumi Emori. Proc Natl Acad Sci U S A 2002
Tadashi Suzuki, Keiichi Yano, Seiji Sugimoto, Ken Kitajima, William J Lennarz, Sadako Inoue, Yasuo Inoue, Yasufumi Emori. Proc Natl Acad Sci U S A 2002
20
Demonstration of peptide:N-glycosidase F activity in endo-beta-N-acetylglucosaminidase F preparations.
T H Plummer, J H Elder, S Alexander, A W Phelan, A L Tarentino. J Biol Chem 1984
T H Plummer, J H Elder, S Alexander, A W Phelan, A L Tarentino. J Biol Chem 1984
20
Identification of two discrete peptide: N-glycanases in Oryzias latipes during embryogenesis.
A Seko, K Kitajima, T Iwamatsu, Y Inoue, S Inoue. Glycobiology 1999
A Seko, K Kitajima, T Iwamatsu, Y Inoue, S Inoue. Glycobiology 1999
31
Demonstration of a new amidase acting on glycopeptides.
N Takahashi. Biochem Biophys Res Commun 1977
N Takahashi. Biochem Biophys Res Commun 1977
20
Peptide:N-glycosidase activity found in the early embryos of Oryzias latipes (Medaka fish). The first demonstration of the occurrence of peptide:N-glycosidase in animal cells and its implication for the presence of a de-N-glycosylation system in living organisms.
A Seko, K Kitajima, Y Inoue, S Inoue. J Biol Chem 1991
A Seko, K Kitajima, Y Inoue, S Inoue. J Biol Chem 1991
20
Unique peptide:N-glycanase of Caenorhabditis elegans has activity of protein disulphide reductase as well as of deglycosylation.
Toshihiko Kato, Akihito Kawahara, Hisashi Ashida, Kenji Yamamoto. J Biochem 2007
Toshihiko Kato, Akihito Kawahara, Hisashi Ashida, Kenji Yamamoto. J Biochem 2007
33
Purification and enzymatic properties of peptide:N-glycanase from C3H mouse-derived L-929 fibroblast cells. Possible widespread occurrence of post-translational remodification of proteins by N-deglycosylation.
T Suzuki, A Seko, K Kitajima, Y Inoue, S Inoue. J Biol Chem 1994
T Suzuki, A Seko, K Kitajima, Y Inoue, S Inoue. J Biol Chem 1994
20
Yeast N-glycanase distinguishes between native and non-native glycoproteins.
Christian Hirsch, Shahram Misaghi, Daniël Blom, Michael E Pacold, Hidde L Ploegh. EMBO Rep 2004
Christian Hirsch, Shahram Misaghi, Daniël Blom, Michael E Pacold, Hidde L Ploegh. EMBO Rep 2004
20
Site-specific de-N-glycosylation of diglycosylated ovalbumin in hen oviduct by endogenous peptide: N-glycanase as a quality control system for newly synthesized proteins.
T Suzuki, K Kitajima, Y Emori, Y Inoue, S Inoue. Proc Natl Acad Sci U S A 1997
T Suzuki, K Kitajima, Y Emori, Y Inoue, S Inoue. Proc Natl Acad Sci U S A 1997
20
Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module.
Xiaoke Zhou, Gang Zhao, James J Truglio, Liqun Wang, Guangtao Li, William J Lennarz, Hermann Schindelin. Proc Natl Acad Sci U S A 2006
Xiaoke Zhou, Gang Zhao, James J Truglio, Liqun Wang, Guangtao Li, William J Lennarz, Hermann Schindelin. Proc Natl Acad Sci U S A 2006
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.