Karina Alviña, Kamran Khodakhah. J Neurosci 2010
Times Cited: 115
Times Cited: 115
Times Cited
Times Co-cited
Similarity
Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia.
Joy T Walter, Karina Alviña, Mary D Womack, Carolyn Chevez, Kamran Khodakhah. Nat Neurosci 2006
Joy T Walter, Karina Alviña, Mary D Womack, Carolyn Chevez, Kamran Khodakhah. Nat Neurosci 2006
39
Treatment of episodic ataxia type 2 with the potassium channel blocker 4-aminopyridine.
M Strupp, R Kalla, M Dichgans, T Freilinger, S Glasauer, T Brandt. Neurology 2004
M Strupp, R Kalla, M Dichgans, T Freilinger, S Glasauer, T Brandt. Neurology 2004
33
A randomized trial of 4-aminopyridine in EA2 and related familial episodic ataxias.
M Strupp, R Kalla, J Claassen, C Adrion, U Mansmann, T Klopstock, T Freilinger, H Neugebauer, R Spiegel, M Dichgans,[...]. Neurology 2011
M Strupp, R Kalla, J Claassen, C Adrion, U Mansmann, T Klopstock, T Freilinger, H Neugebauer, R Spiegel, M Dichgans,[...]. Neurology 2011
31
4-aminopyridine restores vertical and horizontal neural integrator function in downbeat nystagmus.
Roger Kalla, Stefan Glasauer, Ulrich Büttner, Thomas Brandt, Michael Strupp. Brain 2007
Roger Kalla, Stefan Glasauer, Ulrich Büttner, Thomas Brandt, Michael Strupp. Brain 2007
38
KCa channels as therapeutic targets in episodic ataxia type-2.
Karina Alviña, Kamran Khodakhah. J Neurosci 2010
Karina Alviña, Kamran Khodakhah. J Neurosci 2010
38
Treatment of downbeat nystagmus with 3,4-diaminopyridine: a placebo-controlled study.
M Strupp, O Schüler, S Krafczyk, K Jahn, F Schautzer, U Büttner, T Brandt. Neurology 2003
M Strupp, O Schüler, S Krafczyk, K Jahn, F Schautzer, U Büttner, T Brandt. Neurology 2003
29
Detection of floccular hypometabolism in downbeat nystagmus by fMRI.
R Kalla, A Deutschlander, K Hufner, T Stephan, K Jahn, S Glasauer, T Brandt, M Strupp. Neurology 2006
R Kalla, A Deutschlander, K Hufner, T Stephan, K Jahn, S Glasauer, T Brandt, M Strupp. Neurology 2006
33
Highly 4-aminopyridine sensitive delayed rectifier current modulates the excitability of guinea pig cerebellar Purkinje cells.
Y Etzion, Y Grossman. Exp Brain Res 2001
Y Etzion, Y Grossman. Exp Brain Res 2001
27
Early changes in cerebellar physiology accompany motor dysfunction in the polyglutamine disease spinocerebellar ataxia type 3.
Vikram G Shakkottai, Maria do Carmo Costa, James M Dell'Orco, Ananthakrishnan Sankaranarayanan, Heike Wulff, Henry L Paulson. J Neurosci 2011
Vikram G Shakkottai, Maria do Carmo Costa, James M Dell'Orco, Ananthakrishnan Sankaranarayanan, Heike Wulff, Henry L Paulson. J Neurosci 2011
19
Selective positive modulator of calcium-activated potassium channels exerts beneficial effects in a mouse model of spinocerebellar ataxia type 2.
Adebimpe W Kasumu, Charlotte Hougaard, Frederik Rode, Thomas A Jacobsen, Jean Marc Sabatier, Birgitte L Eriksen, Dorte Strøbæk, Xia Liang, Polina Egorova, Dasha Vorontsova,[...]. Chem Biol 2012
Adebimpe W Kasumu, Charlotte Hougaard, Frederik Rode, Thomas A Jacobsen, Jean Marc Sabatier, Birgitte L Eriksen, Dorte Strøbæk, Xia Liang, Polina Egorova, Dasha Vorontsova,[...]. Chem Biol 2012
22
Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4.
R A Ophoff, G M Terwindt, M N Vergouwe, R van Eijk, P J Oefner, S M Hoffman, J E Lamerdin, H W Mohrenweiser, D E Bulman, M Ferrari,[...]. Cell 1996
R A Ophoff, G M Terwindt, M N Vergouwe, R van Eijk, P J Oefner, S M Hoffman, J E Lamerdin, H W Mohrenweiser, D E Bulman, M Ferrari,[...]. Cell 1996
18
Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2.
Stephen T Hansen, Pratap Meera, Thomas S Otis, Stefan M Pulst. Hum Mol Genet 2013
Stephen T Hansen, Pratap Meera, Thomas S Otis, Stefan M Pulst. Hum Mol Genet 2013
18
Increased noise level of purkinje cell activities minimizes impact of their modulation during sensorimotor control.
F E Hoebeek, J S Stahl, A M van Alphen, M Schonewille, C Luo, M Rutteman, A M J M van den Maagdenberg, P C Molenaar, H H L M Goossens, M A Frens,[...]. Neuron 2005
F E Hoebeek, J S Stahl, A M van Alphen, M Schonewille, C Luo, M Rutteman, A M J M van den Maagdenberg, P C Molenaar, H H L M Goossens, M A Frens,[...]. Neuron 2005
18
Downbeat nystagmus: aetiology and comorbidity in 117 patients.
J N Wagner, M Glaser, T Brandt, M Strupp. J Neurol Neurosurg Psychiatry 2008
J N Wagner, M Glaser, T Brandt, M Strupp. J Neurol Neurosurg Psychiatry 2008
17
4-aminopyridine and cerebellar gait: a retrospective case series.
Roman Schniepp, Max Wuehr, Maximilian Neuhaeusser, Ann Kathrin Benecke, Christine Adrion, Thomas Brandt, Michael Strupp, Klaus Jahn. J Neurol 2012
Roman Schniepp, Max Wuehr, Maximilian Neuhaeusser, Ann Kathrin Benecke, Christine Adrion, Thomas Brandt, Michael Strupp, Klaus Jahn. J Neurol 2012
40
Aminopyridines correct early dysfunction and delay neurodegeneration in a mouse model of spinocerebellar ataxia type 1.
Raphael Hourez, Laurent Servais, David Orduz, David Gall, Isabelle Millard, Alban de Kerchove d'Exaerde, Guy Cheron, Harry T Orr, Massimo Pandolfo, Serge N Schiffmann. J Neurosci 2011
Raphael Hourez, Laurent Servais, David Orduz, David Gall, Isabelle Millard, Alban de Kerchove d'Exaerde, Guy Cheron, Harry T Orr, Massimo Pandolfo, Serge N Schiffmann. J Neurosci 2011
19
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2.
Jing Liu, Tie-Shan Tang, Huiping Tu, Omar Nelson, Emily Herndon, Duong P Huynh, Stefan M Pulst, Ilya Bezprozvanny. J Neurosci 2009
Jing Liu, Tie-Shan Tang, Huiping Tu, Omar Nelson, Emily Herndon, Duong P Huynh, Stefan M Pulst, Ilya Bezprozvanny. J Neurosci 2009
16
4-aminopyridine restores visual ocular motor function in upbeat nystagmus.
S Glasauer, R Kalla, U Büttner, M Strupp, T Brandt. J Neurol Neurosurg Psychiatry 2005
S Glasauer, R Kalla, U Büttner, M Strupp, T Brandt. J Neurol Neurosurg Psychiatry 2005
26
Primary episodic ataxias: diagnosis, pathogenesis and treatment.
J C Jen, T D Graves, E J Hess, M G Hanna, R C Griggs, R W Baloh. Brain 2007
J C Jen, T D Graves, E J Hess, M G Hanna, R C Griggs, R W Baloh. Brain 2007
14
Comparison of 10-mg doses of 4-aminopyridine and 3,4-diaminopyridine for the treatment of downbeat nystagmus.
Roger Kalla, Rainer Spiegel, Jens Claassen, Stanislavs Bardins, Ales Hahn, Erich Schneider, Nicole Rettinger, Stefan Glasauer, Thomas Brandt, Michael Strupp. J Neuroophthalmol 2011
Roger Kalla, Rainer Spiegel, Jens Claassen, Stanislavs Bardins, Ales Hahn, Erich Schneider, Nicole Rettinger, Stefan Glasauer, Thomas Brandt, Michael Strupp. J Neuroophthalmol 2011
46
Potassium channel blockers inhibit the triggers of attacks in the calcium channel mouse mutant tottering.
Catherine J C Weisz, Robert S Raike, Luis E Soria-Jasso, Ellen J Hess. J Neurosci 2005
Catherine J C Weisz, Robert S Raike, Luis E Soria-Jasso, Ellen J Hess. J Neurosci 2005
27
A randomised double-blind, cross-over trial of 4-aminopyridine for downbeat nystagmus--effects on slowphase eye velocity, postural stability, locomotion and symptoms.
Jens Claassen, Rainer Spiegel, Roger Kalla, Mary Faldon, Christopher Kennard, Chotipat Danchaivijitr, Stanislaw Bardins, Nicole Rettinger, Erich Schneider, Thomas Brandt,[...]. J Neurol Neurosurg Psychiatry 2013
Jens Claassen, Rainer Spiegel, Roger Kalla, Mary Faldon, Christopher Kennard, Chotipat Danchaivijitr, Stanislaw Bardins, Nicole Rettinger, Erich Schneider, Thomas Brandt,[...]. J Neurol Neurosurg Psychiatry 2013
25
Effects of ablation of flocculus and paraflocculus of eye movements in primate.
D S Zee, A Yamazaki, P H Butler, G Gücer. J Neurophysiol 1981
D S Zee, A Yamazaki, P H Butler, G Gücer. J Neurophysiol 1981
12
4-aminopyridine improves downbeat nystagmus, smooth pursuit, and VOR gain.
R Kalla, S Glasauer, F Schautzer, N Lehnen, U Büttner, M Strupp, T Brandt. Neurology 2004
R Kalla, S Glasauer, F Schautzer, N Lehnen, U Büttner, M Strupp, T Brandt. Neurology 2004
21
Aminopyridines for the treatment of cerebellar and ocular motor disorders.
Michael Strupp, Roger Kalla, Stefan Glasauer, Judith Wagner, Katharina Hüfner, Klaus Jahn, Thomas Brandt. Prog Brain Res 2008
Michael Strupp, Roger Kalla, Stefan Glasauer, Judith Wagner, Katharina Hüfner, Klaus Jahn, Thomas Brandt. Prog Brain Res 2008
31
Tonic synaptic inhibition modulates neuronal output pattern and spatiotemporal synaptic integration.
M Häusser, B A Clark. Neuron 1997
M Häusser, B A Clark. Neuron 1997
12
Cerebellar ataxia by enhanced Ca(V)2.1 currents is alleviated by Ca2+-dependent K+-channel activators in Cacna1a(S218L) mutant mice.
Zhenyu Gao, Boyan Todorov, Curtis F Barrett, Stijn van Dorp, Michel D Ferrari, Arn M J M van den Maagdenberg, Chris I De Zeeuw, Freek E Hoebeek. J Neurosci 2012
Zhenyu Gao, Boyan Todorov, Curtis F Barrett, Stijn van Dorp, Michel D Ferrari, Arn M J M van den Maagdenberg, Chris I De Zeeuw, Freek E Hoebeek. J Neurosci 2012
18
11
Chronic suppression of inositol 1,4,5-triphosphate receptor-mediated calcium signaling in cerebellar purkinje cells alleviates pathological phenotype in spinocerebellar ataxia 2 mice.
Adebimpe W Kasumu, Xia Liang, Polina Egorova, Daria Vorontsova, Ilya Bezprozvanny. J Neurosci 2012
Adebimpe W Kasumu, Xia Liang, Polina Egorova, Daria Vorontsova, Ilya Bezprozvanny. J Neurosci 2012
13
Consensus paper: management of degenerative cerebellar disorders.
W Ilg, A J Bastian, S Boesch, R G Burciu, P Celnik, J Claaßen, K Feil, R Kalla, I Miyai, W Nachbauer,[...]. Cerebellum 2014
W Ilg, A J Bastian, S Boesch, R G Burciu, P Celnik, J Claaßen, K Feil, R Kalla, I Miyai, W Nachbauer,[...]. Cerebellum 2014
11
Spinocerebellar ataxia type 6 protein aggregates cause deficits in motor learning and cerebellar plasticity.
Melanie D Mark, Martin Krause, Henk-Jan Boele, Wolfgang Kruse, Stefan Pollok, Thomas Kuner, Deniz Dalkara, Sebastiaan Koekkoek, Chris I De Zeeuw, Stefan Herlitze. J Neurosci 2015
Melanie D Mark, Martin Krause, Henk-Jan Boele, Wolfgang Kruse, Stefan Pollok, Thomas Kuner, Deniz Dalkara, Sebastiaan Koekkoek, Chris I De Zeeuw, Stefan Herlitze. J Neurosci 2015
27
Riluzole in patients with hereditary cerebellar ataxia: a randomised, double-blind, placebo-controlled trial.
Silvia Romano, Giulia Coarelli, Christian Marcotulli, Luca Leonardi, Francesca Piccolo, Maria Spadaro, Marina Frontali, Michela Ferraldeschi, Maria Chiara Vulpiani, Federica Ponzelli,[...]. Lancet Neurol 2015
Silvia Romano, Giulia Coarelli, Christian Marcotulli, Luca Leonardi, Francesca Piccolo, Maria Spadaro, Marina Frontali, Michela Ferraldeschi, Maria Chiara Vulpiani, Federica Ponzelli,[...]. Lancet Neurol 2015
11
Neuronal Atrophy Early in Degenerative Ataxia Is a Compensatory Mechanism to Regulate Membrane Excitability.
James M Dell'Orco, Aaron H Wasserman, Ravi Chopra, Melissa A C Ingram, Yuan-Shih Hu, Vikrant Singh, Heike Wulff, Puneet Opal, Harry T Orr, Vikram G Shakkottai. J Neurosci 2015
James M Dell'Orco, Aaron H Wasserman, Ravi Chopra, Melissa A C Ingram, Yuan-Shih Hu, Vikrant Singh, Heike Wulff, Puneet Opal, Harry T Orr, Vikram G Shakkottai. J Neurosci 2015
17
In vivo analysis of cerebellar Purkinje cell activity in SCA2 transgenic mouse model.
Polina A Egorova, Olga A Zakharova, Olga L Vlasova, Ilya B Bezprozvanny. J Neurophysiol 2016
Polina A Egorova, Olga A Zakharova, Olga L Vlasova, Ilya B Bezprozvanny. J Neurophysiol 2016
26
18F-fluorodeoxyglucose hypometabolism in cerebellar tonsil and flocculus in downbeat nystagmus.
Sandra Bense, Christoph Best, Hans-Georg Buchholz, Valerie Wiener, Mathias Schreckenberger, Peter Bartenstein, Marianne Dieterich. Neuroreport 2006
Sandra Bense, Christoph Best, Hans-Georg Buchholz, Valerie Wiener, Mathias Schreckenberger, Peter Bartenstein, Marianne Dieterich. Neuroreport 2006
27
The effect of 3,4-diaminopyridine on the patients with hereditary pure cerebellar ataxia.
Taiji Tsunemi, Kinya Ishikawa, Kei Tsukui, Takuro Sumi, Ken Kitamura, Hidehiro Mizusawa. J Neurol Sci 2010
Taiji Tsunemi, Kinya Ishikawa, Kei Tsukui, Takuro Sumi, Ken Kitamura, Hidehiro Mizusawa. J Neurol Sci 2010
47
Riluzole in cerebellar ataxia: a randomized, double-blind, placebo-controlled pilot trial.
G Ristori, S Romano, A Visconti, S Cannoni, M Spadaro, M Frontali, F E Pontieri, N Vanacore, M Salvetti. Neurology 2010
G Ristori, S Romano, A Visconti, S Cannoni, M Spadaro, M Frontali, F E Pontieri, N Vanacore, M Salvetti. Neurology 2010
10
4-Aminopyridine improves gait variability in cerebellar ataxia due to CACNA 1A mutation.
Roman Schniepp, Max Wuehr, Nibal Ackl, Adrian Danek, Thomas Brandt, Michael Strupp, Klaus Jahn. J Neurol 2011
Roman Schniepp, Max Wuehr, Nibal Ackl, Adrian Danek, Thomas Brandt, Michael Strupp, Klaus Jahn. J Neurol 2011
41
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3.
Xi Chen, Tie-Shan Tang, Huiping Tu, Omar Nelson, Mark Pook, Robert Hammer, Nobuyuki Nukina, Ilya Bezprozvanny. J Neurosci 2008
Xi Chen, Tie-Shan Tang, Huiping Tu, Omar Nelson, Mark Pook, Robert Hammer, Nobuyuki Nukina, Ilya Bezprozvanny. J Neurosci 2008
10
Somatic and dendritic small-conductance calcium-activated potassium channels regulate the output of cerebellar Purkinje neurons.
Mary D Womack, Kamran Khodakhah. J Neurosci 2003
Mary D Womack, Kamran Khodakhah. J Neurosci 2003
10
Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons.
I M Raman, B P Bean. J Neurosci 1999
I M Raman, B P Bean. J Neurosci 1999
10
Purkinje neuron synchrony elicits time-locked spiking in the cerebellar nuclei.
Abigail L Person, Indira M Raman. Nature 2011
Abigail L Person, Indira M Raman. Nature 2011
10
Pharmacotherapy of vestibular and ocular motor disorders, including nystagmus.
Michael Strupp, Matthew J Thurtell, Aasef G Shaikh, Thomas Brandt, David S Zee, R John Leigh. J Neurol 2011
Michael Strupp, Matthew J Thurtell, Aasef G Shaikh, Thomas Brandt, David S Zee, R John Leigh. J Neurol 2011
15
Spatiotemporal firing patterns in the cerebellum.
Chris I De Zeeuw, Freek E Hoebeek, Laurens W J Bosman, Martijn Schonewille, Laurens Witter, Sebastiaan K Koekkoek. Nat Rev Neurosci 2011
Chris I De Zeeuw, Freek E Hoebeek, Laurens W J Bosman, Martijn Schonewille, Laurens Witter, Sebastiaan K Koekkoek. Nat Rev Neurosci 2011
10
Effects of dalfampridine on attacks in patients with episodic ataxia type 2: an observational study.
Jens Claassen, Julian Teufel, Roger Kalla, Rainer Spiegel, Michael Strupp. J Neurol 2013
Jens Claassen, Julian Teufel, Roger Kalla, Rainer Spiegel, Michael Strupp. J Neurol 2013
47
Effects of acetyl-DL-leucine in patients with cerebellar ataxia: a case series.
Michael Strupp, Julian Teufel, Maximilian Habs, Regina Feuerecker, Carolin Muth, Bart P van de Warrenburg, Thomas Klopstock, Katharina Feil. J Neurol 2013
Michael Strupp, Julian Teufel, Maximilian Habs, Regina Feuerecker, Carolin Muth, Bart P van de Warrenburg, Thomas Klopstock, Katharina Feil. J Neurol 2013
19
4-aminopyridine reverses ataxia and cerebellar firing deficiency in a mouse model of spinocerebellar ataxia type 6.
Sriram Jayabal, Hui Ho Vanessa Chang, Kathleen E Cullen, Alanna J Watt. Sci Rep 2016
Sriram Jayabal, Hui Ho Vanessa Chang, Kathleen E Cullen, Alanna J Watt. Sci Rep 2016
23
Hereditary paroxysmal ataxia: response to acetazolamide.
R C Griggs, R T Moxley, R A Lafrance, J McQuillen. Neurology 1978
R C Griggs, R T Moxley, R A Lafrance, J McQuillen. Neurology 1978
9
Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or human.
D P Huynh, K Figueroa, N Hoang, S M Pulst. Nat Genet 2000
D P Huynh, K Figueroa, N Hoang, S M Pulst. Nat Genet 2000
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.