A citation-based method for searching scientific literature

Ping Wei, Marlena Walls, Ming Qiu, Richard Ding, Robert H Denlinger, Anthony Wong, Kosta Tsaparikos, Jitesh P Jani, Natilie Hosea, Michelle Sands, Sophia Randolph, Tod Smeal. Mol Cancer Ther 2010
Times Cited: 143







List of co-cited articles
1462 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
34

Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
516
27

Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia.
Jeremy B Samon, Mireia Castillo-Martin, Michael Hadler, Alberto Ambesi-Impiobato, Elisabeth Paietta, Janis Racevskis, Peter H Wiernik, Jacob M Rowe, John Jakubczak, Sophia Randolph,[...]. Mol Cancer Ther 2012
83
32

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga,[...]. Nat Med 2009
323
23

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
21

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.
Johan H van Es, Marielle E van Gijn, Orbicia Riccio, Maaike van den Born, Marc Vooijs, Harry Begthel, Miranda Cozijnsen, Sylvie Robine, Doug J Winton, Freddy Radtke,[...]. Nature 2005
20

Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors.
Anthony W Tolcher, Wells A Messersmith, Stanislaw M Mikulski, Kyriakos P Papadopoulos, Eunice L Kwak, Darlene G Gibbon, Amita Patnaik, Gerald S Falchook, Arvind Dasari, Geoffrey I Shapiro,[...]. J Clin Oncol 2012
175
19

Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors.
Ian Krop, Tim Demuth, Tina Guthrie, Patrick Y Wen, Warren P Mason, Prakash Chinnaiyan, Nicholas Butowski, Morris D Groves, Santosh Kesari, Steven J Freedman,[...]. J Clin Oncol 2012
214
18



Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
660
17

Biomarker and pharmacologic evaluation of the γ-secretase inhibitor PF-03084014 in breast cancer models.
Cathy C Zhang, Adam Pavlicek, Qin Zhang, Maruja E Lira, Cory L Painter, Zhengming Yan, Xianxian Zheng, Nathan V Lee, Mark Ozeck, Ming Qiu,[...]. Clin Cancer Res 2012
56
28

Direct inhibition of the NOTCH transcription factor complex.
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
559
16

A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.
C Papayannidis, D J DeAngelo, W Stock, B Huang, M N Shaik, R Cesari, X Zheng, J M Reynolds, P A English, M Ozeck,[...]. Blood Cancer J 2015
71
21

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
B De Strooper, W Annaert, P Cupers, P Saftig, K Craessaerts, J S Mumm, E H Schroeter, V Schrijvers, M S Wolfe, W J Ray,[...]. Nature 1999
14

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis.
John Ridgway, Gu Zhang, Yan Wu, Scott Stawicki, Wei-Ching Liang, Yvan Chanthery, Joe Kowalski, Ryan J Watts, Christopher Callahan, Ian Kasman,[...]. Nature 2006
735
14

A Phase I, dose-finding study in patients with advanced solid malignancies of the oral γ-secretase inhibitor PF-03084014.
Wells A Messersmith, Geoffrey I Shapiro, James M Cleary, Antonio Jimeno, Arvind Dasari, Bo Huang, M Naveed Shaik, Rossano Cesari, Xianxian Zheng, Jennifer M Reynolds,[...]. Clin Cancer Res 2015
126
14

Phase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study.
Maryam Fouladi, Clinton F Stewart, James Olson, Lars M Wagner, Arzu Onar-Thomas, Mehmet Kocak, Roger J Packer, Stewart Goldman, Sridharan Gururangan, Amar Gajjar,[...]. J Clin Oncol 2011
115
13

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
Miguel Aste-Amézaga, Ningyan Zhang, Janet E Lineberger, Beth A Arnold, Timothy J Toner, Mingcheng Gu, Lingyi Huang, Salvatore Vitelli, Kim T Vo, Peter Haytko,[...]. PLoS One 2010
130
12

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
Andrew P Weng, John M Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G Rodriguez, Hong Sai, John Tobias,[...]. Genes Dev 2006
627
12

Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
12

Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer.
Shinichi Yabuuchi, Shweta G Pai, Nathaniel R Campbell, Roeland F de Wilde, Elizabeth De Oliveira, Preethi Korangath, Mirte M Streppel, Zeshaan A Rasheed, Manuel Hidalgo, Anirban Maitra,[...]. Cancer Lett 2013
96
12

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
494
12

A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors.
Elena Gabriela Chiorean, Patricia LoRusso, Robert Matthew Strother, Jennifer R Diamond, Anne Younger, Wells A Messersmith, Lieve Adriaens, Liming Liu, Richard J Kao, Albert Thomas DiCioccio,[...]. Clin Cancer Res 2015
79
15

Preclinical profile of a potent gamma-secretase inhibitor targeting notch signaling with in vivo efficacy and pharmacodynamic properties.
Leopoldo Luistro, Wei He, Melissa Smith, Kathryn Packman, Maria Vilenchik, Daisy Carvajal, John Roberts, James Cai, Windy Berkofsky-Fessler, Holly Hilton,[...]. Cancer Res 2009
146
11

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia.
Xose S Puente, Magda Pinyol, Víctor Quesada, Laura Conde, Gonzalo R Ordóñez, Neus Villamor, Georgia Escaramis, Pedro Jares, Sílvia Beà, Marcos González-Díaz,[...]. Nature 2011
11

Synergistic effect of the γ-secretase inhibitor PF-03084014 and docetaxel in breast cancer models.
Cathy C Zhang, Zhengming Yan, Qing Zong, Douglas D Fang, Cory Painter, Qin Zhang, Enhong Chen, Maruja E Lira, Annette John-Baptiste, James G Christensen. Stem Cells Transl Med 2013
61
18

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis.
Irene Noguera-Troise, Christopher Daly, Nicholas J Papadopoulos, Sandra Coetzee, Pat Boland, Nicholas W Gale, Hsin Chieh Lin, George D Yancopoulos, Gavin Thurston. Nature 2006
774
11

A phase 3 trial of semagacestat for treatment of Alzheimer's disease.
Rachelle S Doody, Rema Raman, Martin Farlow, Takeshi Iwatsubo, Bruno Vellas, Steven Joffe, Karl Kieburtz, Feng He, Xiaoying Sun, Ronald G Thomas,[...]. N Engl J Med 2013
699
11

Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence.
K Pandya, K Meeke, A G Clementz, A Rogowski, J Roberts, L Miele, K S Albain, C Osipo. Br J Cancer 2011
96
11

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Birgit Knoechel, Justine E Roderick, Kaylyn E Williamson, Jiang Zhu, Jens G Lohr, Matthew J Cotton, Shawn M Gillespie, Daniel Fernandez, Manching Ku, Hongfang Wang,[...]. Nat Genet 2014
236
11

Aberrant activation of notch signaling in human breast cancer.
Spyros Stylianou, Rob B Clarke, Keith Brennan. Cancer Res 2006
412
10

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.
Joseph Milano, Jenny McKay, Claude Dagenais, Linda Foster-Brown, Francois Pognan, Reto Gadient, Robert T Jacobs, Anna Zacco, Barry Greenberg, Paul J Ciaccio. Toxicol Sci 2004
412
10

Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation.
Gwendolyn T Wong, Denise Manfra, Frederique M Poulet, Qi Zhang, Hubert Josien, Thomas Bara, Laura Engstrom, Maria Pinzon-Ortiz, Jay S Fine, Hu-Jung J Lee,[...]. J Biol Chem 2004
570
10


High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival.
Michael Reedijk, Silvia Odorcic, Lynn Chang, Hui Zhang, Naomi Miller, David R McCready, Gina Lockwood, Sean E Egan. Cancer Res 2005
560
10

A phase I study of the oral gamma secretase inhibitor R04929097 in combination with gemcitabine in patients with advanced solid tumors (PHL-078/CTEP 8575).
Suzanne Richter, Philippe L Bedard, Eric Xueyu Chen, Blaise A Clarke, Ben Tran, Sebastien J Hotte, Anastasios Stathis, Hal W Hirte, Albiruni R A Razak, Michael Reedijk,[...]. Invest New Drugs 2014
58
17


Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a γ-secretase inhibitor, in a preclinical colorectal explant model.
J J Arcaroli, K S Quackenbush, A Purkey, R W Powell, T M Pitts, S Bagby, A C Tan, B Cross, K McPhillips, E-K Song,[...]. Br J Cancer 2013
28
35

Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor.
Kevin W Gillman, John E Starrett, Michael F Parker, Kai Xie, Joanne J Bronson, Lawrence R Marcin, Kate E McElhone, Carl P Bergstrom, Robert A Mate, Richard Williams,[...]. ACS Med Chem Lett 2010
125
9

Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors.
Anne F Schott, Melissa D Landis, Gabriela Dontu, Kent A Griffith, Rachel M Layman, Ian Krop, Lacey A Paskett, Helen Wong, Lacey E Dobrolecki, Michael T Lewis,[...]. Clin Cancer Res 2013
156
9

A phase Ib combination study of RO4929097, a gamma-secretase inhibitor, and temsirolimus in patients with advanced solid tumors.
Ivan Diaz-Padilla, Hal Hirte, Amit M Oza, Blaise A Clarke, Brenda Cohen, Michael Reedjik, Tong Zhang, Suzanne Kamel-Reid, S Percy Ivy, Sebastien J Hotte,[...]. Invest New Drugs 2013
43
20


The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia.
Benjamin J Thompson, Silvia Buonamici, Maria Luisa Sulis, Teresa Palomero, Tomas Vilimas, Giuseppe Basso, Adolfo Ferrando, Iannis Aifantis. J Exp Med 2007
348
9

Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors.
Ashvinikumar V Gavai, Claude Quesnelle, Derek Norris, Wen-Ching Han, Patrice Gill, Weifang Shan, Aaron Balog, Ke Chen, Andrew Tebben, Richard Rampulla,[...]. ACS Med Chem Lett 2015
47
19

Therapeutic modulation of Notch signalling--are we there yet?
Emma R Andersson, Urban Lendahl. Nat Rev Drug Discov 2014
314
9

A phase II study of the gamma secretase inhibitor RO4929097 in patients with previously treated metastatic pancreatic adenocarcinoma.
Ana De Jesus-Acosta, Daniel Laheru, Anirban Maitra, John Arcaroli, Michelle A Rudek, Arvind Dasari, Patrick J Blatchford, Kevin Quackenbush, Wells Messersmith. Invest New Drugs 2014
76
11

Phase 2 study of RO4929097, a gamma-secretase inhibitor, in metastatic melanoma: SWOG 0933.
Sylvia M Lee, James Moon, Bruce G Redman, Tarek Chidiac, Lawrence E Flaherty, Yuanyuan Zha, Megan Othus, Antoni Ribas, Vernon K Sondak, Thomas F Gajewski,[...]. Cancer 2015
62
14

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.
Roger A Habets, Charles E de Bock, Lutgarde Serneels, Inge Lodewijckx, Delphine Verbeke, David Nittner, Rajeshwar Narlawar, Sofie Demeyer, James Dooley, Adrian Liston,[...]. Sci Transl Med 2019
47
19

Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells.
F Xing, H Okuda, M Watabe, A Kobayashi, S K Pai, W Liu, P R Pandey, K Fukuda, S Hirota, T Sugai,[...]. Oncogene 2011
147
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.