Juliette D Godin, Kelly Colombo, Maria Molina-Calavita, Guy Keryer, Diana Zala, Bénédicte C Charrin, Paula Dietrich, Marie-Laure Volvert, François Guillemot, Ioannis Dragatsis, Yohanns Bellaiche, Frédéric Saudou, Laurent Nguyen, Sandrine Humbert. Neuron 2010
Times Cited: 178
Times Cited: 178
Times Cited
Times Co-cited
Similarity
39
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes.
J Nasir, S B Floresco, J R O'Kusky, V M Diewert, J M Richman, J Zeisler, A Borowski, J D Marth, A G Phillips, M R Hayden. Cell 1995
J Nasir, S B Floresco, J R O'Kusky, V M Diewert, J M Richman, J Zeisler, A Borowski, J D Marth, A G Phillips, M R Hayden. Cell 1995
36
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue.
S Zeitlin, J P Liu, D L Chapman, V E Papaioannou, A Efstratiadis. Nat Genet 1995
S Zeitlin, J P Liu, D L Chapman, V E Papaioannou, A Efstratiadis. Nat Genet 1995
34
Inactivation of the mouse Huntington's disease gene homolog Hdh.
M P Duyao, A B Auerbach, A Ryan, F Persichetti, G T Barnes, S M McNeil, P Ge, J P Vonsattel, J F Gusella, A L Joyner. Science 1995
M P Duyao, A B Auerbach, A Ryan, F Persichetti, G T Barnes, S M McNeil, P Ge, J P Vonsattel, J F Gusella, A L Joyner. Science 1995
31
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
28
Huntingtin facilitates dynein/dynactin-mediated vesicle transport.
Juliane P Caviston, Jennifer L Ross, Sheila M Antony, Mariko Tokito, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2007
Juliane P Caviston, Jennifer L Ross, Sheila M Antony, Mariko Tokito, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2007
22
Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice.
I Dragatsis, M S Levine, S Zeitlin. Nat Genet 2000
I Dragatsis, M S Levine, S Zeitlin. Nat Genet 2000
22
Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion.
J K White, W Auerbach, M P Duyao, J P Vonsattel, J F Gusella, A L Joyner, M E MacDonald. Nat Genet 1997
J K White, W Auerbach, M P Duyao, J P Vonsattel, J F Gusella, A L Joyner, M E MacDonald. Nat Genet 1997
21
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R Leavitt, Michael R Hayden, Tõnis Timmusk,[...]. Nat Genet 2003
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R Leavitt, Michael R Hayden, Tõnis Timmusk,[...]. Nat Genet 2003
20
Huntingtin functions as a scaffold for selective macroautophagy.
Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F Stimming, Hugo J Bellen,[...]. Nat Cell Biol 2015
Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F Stimming, Hugo J Bellen,[...]. Nat Cell Biol 2015
20
Mutant huntingtin affects cortical progenitor cell division and development of the mouse neocortex.
Maria Molina-Calavita, Monia Barnat, Salah Elias, Esther Aparicio, Matthieu Piel, Sandrine Humbert. J Neurosci 2014
Maria Molina-Calavita, Monia Barnat, Salah Elias, Esther Aparicio, Matthieu Piel, Sandrine Humbert. J Neurosci 2014
43
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
18
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
17
Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington's disease.
Aldrin E Molero, Eduardo E Arteaga-Bracho, Christopher H Chen, Maria Gulinello, Michael L Winchester, Nandini Pichamoorthy, Solen Gokhan, Kamran Khodakhah, Mark F Mehler. Proc Natl Acad Sci U S A 2016
Aldrin E Molero, Eduardo E Arteaga-Bracho, Christopher H Chen, Maria Gulinello, Michael L Winchester, Nandini Pichamoorthy, Solen Gokhan, Kamran Khodakhah, Mark F Mehler. Proc Natl Acad Sci U S A 2016
23
Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits.
Spencer U McKinstry, Yonca B Karadeniz, Atesh K Worthington, Volodya Y Hayrapetyan, M Ilcim Ozlu, Karol Serafin-Molina, W Christopher Risher, Tuna Ustunkaya, Ioannis Dragatsis, Scott Zeitlin,[...]. J Neurosci 2014
Spencer U McKinstry, Yonca B Karadeniz, Atesh K Worthington, Volodya Y Hayrapetyan, M Ilcim Ozlu, Karol Serafin-Molina, W Christopher Risher, Tuna Ustunkaya, Ioannis Dragatsis, Scott Zeitlin,[...]. J Neurosci 2014
22
Potential function for the Huntingtin protein as a scaffold for selective autophagy.
Joseph Ochaba, Tamás Lukacsovich, George Csikos, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice L Lau, Sylvia Y Yeung, Sandrine Humbert,[...]. Proc Natl Acad Sci U S A 2014
Joseph Ochaba, Tamás Lukacsovich, George Csikos, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice L Lau, Sylvia Y Yeung, Sandrine Humbert,[...]. Proc Natl Acad Sci U S A 2014
16
Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
16
Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons.
Emilie Colin, Diana Zala, Géraldine Liot, Hélène Rangone, Maria Borrell-Pagès, Xiao-Jiang Li, Frédéric Saudou, Sandrine Humbert. EMBO J 2008
Emilie Colin, Diana Zala, Géraldine Liot, Hélène Rangone, Maria Borrell-Pagès, Xiao-Jiang Li, Frédéric Saudou, Sandrine Humbert. EMBO J 2008
15
Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin.
Rona K Graham, Yu Deng, Elizabeth J Slow, Brendan Haigh, Nagat Bissada, Ge Lu, Jacqueline Pearson, Jacqueline Shehadeh, Lisa Bertram, Zoe Murphy,[...]. Cell 2006
Rona K Graham, Yu Deng, Elizabeth J Slow, Brendan Haigh, Nagat Bissada, Ge Lu, Jacqueline Pearson, Jacqueline Shehadeh, Lisa Bertram, Zoe Murphy,[...]. Cell 2006
15
Network organization of the huntingtin proteomic interactome in mammalian brain.
Dyna I Shirasaki, Erin R Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A Loo,[...]. Neuron 2012
Dyna I Shirasaki, Erin R Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A Loo,[...]. Neuron 2012
15
Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease.
Guy Keryer, Jose R Pineda, Géraldine Liot, Jinho Kim, Paula Dietrich, Caroline Benstaali, Karen Smith, Fabrice P Cordelières, Nathalie Spassky, Robert J Ferrante,[...]. J Clin Invest 2011
Guy Keryer, Jose R Pineda, Géraldine Liot, Jinho Kim, Paula Dietrich, Caroline Benstaali, Karen Smith, Fabrice P Cordelières, Nathalie Spassky, Robert J Ferrante,[...]. J Clin Invest 2011
16
Huntingtin regulates mammary stem cell division and differentiation.
Salah Elias, Morgane S Thion, Hua Yu, Cristovao Marques Sousa, Charlène Lasgi, Xavier Morin, Sandrine Humbert. Stem Cell Reports 2014
Salah Elias, Morgane S Thion, Hua Yu, Cristovao Marques Sousa, Charlène Lasgi, Xavier Morin, Sandrine Humbert. Stem Cell Reports 2014
41
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
14
The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
Yvette C Wong, Erika L F Holzbaur. J Neurosci 2014
Yvette C Wong, Erika L F Holzbaur. J Neurosci 2014
14
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
13
Wild-type huntingtin protects neurons from excitotoxicity.
Blair R Leavitt, Jeremy M van Raamsdonk, Jacqueline Shehadeh, Herman Fernandes, Zoe Murphy, Rona K Graham, Cheryl L Wellington, Lynn A Raymond, Michael R Hayden. J Neurochem 2006
Blair R Leavitt, Jeremy M van Raamsdonk, Jacqueline Shehadeh, Herman Fernandes, Zoe Murphy, Rona K Graham, Cheryl L Wellington, Lynn A Raymond, Michael R Hayden. J Neurochem 2006
13
Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice.
. Nat Neurosci 2017
. Nat Neurosci 2017
13
Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: relevance to Huntington's disease.
Guylaine Hoffner, Pascal Kahlem, Philippe Djian. J Cell Sci 2002
Guylaine Hoffner, Pascal Kahlem, Philippe Djian. J Cell Sci 2002
12
Huntingtin facilitates polycomb repressive complex 2.
Ihn Sik Seong, Juliana M Woda, Ji-Joon Song, Alejandro Lloret, Priyanka D Abeyrathne, Caroline J Woo, Gillian Gregory, Jong-Min Lee, Vanessa C Wheeler, Thomas Walz,[...]. Hum Mol Genet 2010
Ihn Sik Seong, Juliana M Woda, Ji-Joon Song, Alejandro Lloret, Priyanka D Abeyrathne, Caroline J Woo, Gillian Gregory, Jong-Min Lee, Vanessa C Wheeler, Thomas Walz,[...]. Hum Mol Genet 2010
12
Wild-type huntingtin plays a role in brain development and neuronal survival.
Anton Reiner, Ioannis Dragatsis, Scott Zeitlin, Daniel Goldowitz. Mol Neurobiol 2003
Anton Reiner, Ioannis Dragatsis, Scott Zeitlin, Daniel Goldowitz. Mol Neurobiol 2003
13
Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons.
John Russel McGuire, Juan Rong, Shi-Hua Li, Xiao-Jiang Li. J Biol Chem 2006
John Russel McGuire, Juan Rong, Shi-Hua Li, Xiao-Jiang Li. J Biol Chem 2006
12
Spatial and temporal requirements for huntingtin (Htt) in neuronal migration and survival during brain development.
Yiai Tong, Thomas J Ha, Li Liu, Andrew Nishimoto, Anton Reiner, Dan Goldowitz. J Neurosci 2011
Yiai Tong, Thomas J Ha, Li Liu, Andrew Nishimoto, Anton Reiner, Dan Goldowitz. J Neurosci 2011
36
Huntingtin-Mediated Multipolar-Bipolar Transition of Newborn Cortical Neurons Is Critical for Their Postnatal Neuronal Morphology.
Monia Barnat, Julien Le Friec, Caroline Benstaali, Sandrine Humbert. Neuron 2017
Monia Barnat, Julien Le Friec, Caroline Benstaali, Sandrine Humbert. Neuron 2017
28
An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin.
Valentina Lo Sardo, Chiara Zuccato, Germano Gaudenzi, Barbara Vitali, Catarina Ramos, Marzia Tartari, Michael A Myre, James A Walker, Anna Pistocchi, Luciano Conti,[...]. Nat Neurosci 2012
Valentina Lo Sardo, Chiara Zuccato, Germano Gaudenzi, Barbara Vitali, Catarina Ramos, Marzia Tartari, Michael A Myre, James A Walker, Anna Pistocchi, Luciano Conti,[...]. Nat Neurosci 2012
15
The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor.
Hiroki Takano, James F Gusella. BMC Neurosci 2002
Hiroki Takano, James F Gusella. BMC Neurosci 2002
11
Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease.
Arun Pal, Fedor Severin, Barbara Lommer, Anna Shevchenko, Marino Zerial. J Cell Biol 2006
Arun Pal, Fedor Severin, Barbara Lommer, Anna Shevchenko, Marino Zerial. J Cell Biol 2006
11
Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
Randy Singh Atwal, Jianrun Xia, Deborah Pinchev, Jillian Taylor, Richard M Epand, Ray Truant. Hum Mol Genet 2007
Randy Singh Atwal, Jianrun Xia, Deborah Pinchev, Jillian Taylor, Richard M Epand, Ray Truant. Hum Mol Genet 2007
11
Normal huntingtin function: an alternative approach to Huntington's disease.
Elena Cattaneo, Chiara Zuccato, Marzia Tartari. Nat Rev Neurosci 2005
Elena Cattaneo, Chiara Zuccato, Marzia Tartari. Nat Rev Neurosci 2005
11
The hunt for huntingtin function: interaction partners tell many different stories.
Phoebe Harjes, Erich E Wanker. Trends Biochem Sci 2003
Phoebe Harjes, Erich E Wanker. Trends Biochem Sci 2003
11
Selective roles of normal and mutant huntingtin in neural induction and early neurogenesis.
Giang D Nguyen, Solen Gokhan, Aldrin E Molero, Mark F Mehler. PLoS One 2013
Giang D Nguyen, Solen Gokhan, Aldrin E Molero, Mark F Mehler. PLoS One 2013
31
Huntington's disease alters human neurodevelopment.
Monia Barnat, Mariacristina Capizzi, Esther Aparicio, Susana Boluda, Doris Wennagel, Radhia Kacher, Rayane Kassem, Sophie Lenoir, Fabienne Agasse, Barbara Y Braz,[...]. Science 2020
Monia Barnat, Mariacristina Capizzi, Esther Aparicio, Susana Boluda, Doris Wennagel, Radhia Kacher, Rayane Kassem, Sophie Lenoir, Fabienne Agasse, Barbara Y Braz,[...]. Science 2020
12
Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.
Daijiro Konno, Go Shioi, Atsunori Shitamukai, Asako Mori, Hiroshi Kiyonari, Takaki Miyata, Fumio Matsuzaki. Nat Cell Biol 2008
Daijiro Konno, Go Shioi, Atsunori Shitamukai, Asako Mori, Hiroshi Kiyonari, Takaki Miyata, Fumio Matsuzaki. Nat Cell Biol 2008
10
Huntingtin as an essential integrator of intracellular vesicular trafficking.
Juliane P Caviston, Erika L F Holzbaur. Trends Cell Biol 2009
Juliane P Caviston, Erika L F Holzbaur. Trends Cell Biol 2009
10
The huntingtin N17 domain is a multifunctional CRM1 and Ran-dependent nuclear and cilial export signal.
T Maiuri, T Woloshansky, J Xia, R Truant. Hum Mol Genet 2013
T Maiuri, T Woloshansky, J Xia, R Truant. Hum Mol Genet 2013
12
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
10
Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
10
Smaller intracranial volume in prodromal Huntington's disease: evidence for abnormal neurodevelopment.
Peggy C Nopoulos, Elizabeth H Aylward, Christopher A Ross, James A Mills, Douglas R Langbehn, Hans J Johnson, Vincent A Magnotta, Ronald K Pierson, Leigh J Beglinger, Martha A Nance,[...]. Brain 2011
Peggy C Nopoulos, Elizabeth H Aylward, Christopher A Ross, James A Mills, Douglas R Langbehn, Hans J Johnson, Vincent A Magnotta, Ronald K Pierson, Leigh J Beglinger, Martha A Nance,[...]. Brain 2011
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.