A citation-based method for searching scientific literature

Tamara Tchkonia, Dean E Morbeck, Thomas Von Zglinicki, Jan Van Deursen, Joseph Lustgarten, Heidi Scrable, Sundeep Khosla, Michael D Jensen, James L Kirkland. Aging Cell 2010
Times Cited: 523







List of co-cited articles
704 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A crucial role for adipose tissue p53 in the regulation of insulin resistance.
Tohru Minamino, Masayuki Orimo, Ippei Shimizu, Takeshige Kunieda, Masataka Yokoyama, Takashi Ito, Aika Nojima, Akira Nabetani, Yuichi Oike, Hisahiro Matsubara,[...]. Nat Med 2009
458
16


Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
15

Targeting senescent cells enhances adipogenesis and metabolic function in old age.
Ming Xu, Allyson K Palmer, Husheng Ding, Megan M Weivoda, Tamar Pirtskhalava, Thomas A White, Anna Sepe, Kurt O Johnson, Michael B Stout, Nino Giorgadze,[...]. Elife 2015
214
15

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding, Nino Giorgadze, Allyson K Palmer, Yuji Ikeno, Gene B Hubbard, Marc Lenburg,[...]. Aging Cell 2015
670
15

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Darren J Baker, Bennett G Childs, Matej Durik, Melinde E Wijers, Cynthia J Sieben, Jian Zhong, Rachel A Saltness, Karthik B Jeganathan, Grace Casaclang Verzosa, Abdulmohammad Pezeshki,[...]. Nature 2016
14

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
14

The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
14

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.
Ming Xu, Tamara Tchkonia, Husheng Ding, Mikolaj Ogrodnik, Ellen R Lubbers, Tamar Pirtskhalava, Thomas A White, Kurt O Johnson, Michael B Stout, Vojtech Mezera,[...]. Proc Natl Acad Sci U S A 2015
262
13

Peripheral fat loss and decline in adipogenesis in older humans.
Giuseppe Caso, Margaret A McNurlan, Izolda Mileva, Alla Zemlyak, Dennis C Mynarcik, Marie C Gelato. Metabolism 2013
37
32

Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
462
12

Targeting senescent cells alleviates obesity-induced metabolic dysfunction.
Allyson K Palmer, Ming Xu, Yi Zhu, Tamar Pirtskhalava, Megan M Weivoda, Christine M Hachfeld, Larissa G Prata, Theo H van Dijk, Esther Verkade, Grace Casaclang-Verzosa,[...]. Aging Cell 2019
118
12

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
12

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study.
Jamie N Justice, Anoop M Nambiar, Tamar Tchkonia, Nathan K LeBrasseur, Rodolfo Pascual, Shahrukh K Hashmi, Larissa Prata, Michal M Masternak, Stephen B Kritchevsky, Nicolas Musi,[...]. EBioMedicine 2019
251
10

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
Tamara Tchkonia, Yi Zhu, Jan van Deursen, Judith Campisi, James L Kirkland. J Clin Invest 2013
767
10


Aging is associated with an increase in T cells and inflammatory macrophages in visceral adipose tissue.
Carey N Lumeng, Jianhua Liu, Lynn Geletka, Colin Delaney, Jennifer Delproposto, Anjali Desai, Kelsie Oatmen, Gabriel Martinez-Santibanez, Annabelle Julius, Sanjay Garg,[...]. J Immunol 2011
137
9

Age-related changes in total and regional fat distribution.
Jennifer L Kuk, Travis J Saunders, Lance E Davidson, Robert Ross. Ageing Res Rev 2009
327
9

Inflamm-aging. An evolutionary perspective on immunosenescence.
C Franceschi, M Bonafè, S Valensin, F Olivieri, M De Luca, E Ottaviani, G De Benedictis. Ann N Y Acad Sci 2000
9

Cellular senescence: when bad things happen to good cells.
Judith Campisi, Fabrizio d'Adda di Fagagna. Nat Rev Mol Cell Biol 2007
9

Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases.
Claudio Franceschi, Judith Campisi. J Gerontol A Biol Sci Med Sci 2014
8

The serial cultivation of human diploid cell strains.
L HAYFLICK, P S MOORHEAD. Exp Cell Res 1961
8

Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.
Allyson K Palmer, Tamara Tchkonia, Nathan K LeBrasseur, Eduardo N Chini, Ming Xu, James L Kirkland. Diabetes 2015
151
8

Cellular Senescence: A Translational Perspective.
James L Kirkland, Tamara Tchkonia. EBioMedicine 2017
291
8

Cellular senescence drives age-dependent hepatic steatosis.
Mikolaj Ogrodnik, Satomi Miwa, Tamar Tchkonia, Dina Tiniakos, Caroline L Wilson, Albert Lahat, Christoper P Day, Alastair Burt, Allyson Palmer, Quentin M Anstee,[...]. Nat Commun 2017
277
8

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.
Carolyn M Roos, Bin Zhang, Allyson K Palmer, Mikolaj B Ogrodnik, Tamar Pirtskhalava, Nassir M Thalji, Michael Hagler, Diana Jurk, Leslie A Smith, Grace Casaclang-Verzosa,[...]. Aging Cell 2016
267
8

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease.
LaTonya J Hickson, Larissa G P Langhi Prata, Shane A Bobart, Tamara K Evans, Nino Giorgadze, Shahrukh K Hashmi, Sandra M Herrmann, Michael D Jensen, Qingyi Jia, Kyra L Jordan,[...]. EBioMedicine 2019
179
8


Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.
Michael B Stout, Tamara Tchkonia, Tamar Pirtskhalava, Allyson K Palmer, Edward O List, Darlene E Berryman, Ellen R Lubbers, Carlos Escande, Adam Spong, Michal M Masternak,[...]. Aging (Albany NY) 2014
71
9

Aging up-regulates expression of inflammatory mediators in mouse adipose tissue.
Dayong Wu, Zhihong Ren, Munkyong Pae, Weimin Guo, Xuelin Cui, Alfred H Merrill, Simin Nikbin Meydani. J Immunol 2007
191
7


Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty.
Michael B Stout, Jamie N Justice, Barbara J Nicklas, James L Kirkland. Physiology (Bethesda) 2017
85
8

Targeting cellular senescence prevents age-related bone loss in mice.
Joshua N Farr, Ming Xu, Megan M Weivoda, David G Monroe, Daniel G Fraser, Jennifer L Onken, Brittany A Negley, Jad G Sfeir, Mikolaj B Ogrodnik, Christine M Hachfeld,[...]. Nat Med 2017
295
7

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
G P Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, E E Medrano, M Linskens, I Rubelj, O Pereira-Smith. Proc Natl Acad Sci U S A 1995
7

Aging, cellular senescence, and cancer.
Judith Campisi. Annu Rev Physiol 2013
7

Cellular senescence in aging and age-related disease: from mechanisms to therapy.
Bennett G Childs, Matej Durik, Darren J Baker, Jan M van Deursen. Nat Med 2015
706
7

The role of senescent cells in ageing.
Jan M van Deursen. Nature 2014
961
7

An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Marco Demaria, Naoko Ohtani, Sameh A Youssef, Francis Rodier, Wendy Toussaint, James R Mitchell, Remi-Martin Laberge, Jan Vijg, Harry Van Steeg, Martijn E T Dollé,[...]. Dev Cell 2014
666
7

A complex secretory program orchestrated by the inflammasome controls paracrine senescence.
Juan Carlos Acosta, Ana Banito, Torsten Wuestefeld, Athena Georgilis, Peggy Janich, Jennifer P Morton, Dimitris Athineos, Tae-Won Kang, Felix Lasitschka, Mindaugas Andrulis,[...]. Nat Cell Biol 2013
771
7

Hallmarks of Cellular Senescence.
Alejandra Hernandez-Segura, Jamil Nehme, Marco Demaria. Trends Cell Biol 2018
382
7

Mechanisms and metabolic implications of regional differences among fat depots.
Tamara Tchkonia, Thomas Thomou, Yi Zhu, Iordanes Karagiannides, Charalabos Pothoulakis, Michael D Jensen, James L Kirkland. Cell Metab 2013
301
7

Ink4a/Arf expression is a biomarker of aging.
Janakiraman Krishnamurthy, Chad Torrice, Matthew R Ramsey, Grigoriy I Kovalev, Khalid Al-Regaiey, Lishan Su, Norman E Sharpless. J Clin Invest 2004
914
6

Geroscience: linking aging to chronic disease.
Brian K Kennedy, Shelley L Berger, Anne Brunet, Judith Campisi, Ana Maria Cuervo, Elissa S Epel, Claudio Franceschi, Gordon J Lithgow, Richard I Morimoto, Jeffrey E Pessin,[...]. Cell 2014
721
6


A senescent cell bystander effect: senescence-induced senescence.
Glyn Nelson, James Wordsworth, Chunfang Wang, Diana Jurk, Conor Lawless, Carmen Martin-Ruiz, Thomas von Zglinicki. Aging Cell 2012
269
6

Identification of Senescent Cells in the Bone Microenvironment.
Joshua N Farr, Daniel G Fraser, Haitao Wang, Katharina Jaehn, Mikolaj B Ogrodnik, Megan M Weivoda, Matthew T Drake, Tamara Tchkonia, Nathan K LeBrasseur, James L Kirkland,[...]. J Bone Miner Res 2016
141
6

Cellular senescence: from physiology to pathology.
Daniel Muñoz-Espín, Manuel Serrano. Nat Rev Mol Cell Biol 2014
999
6

The Impact of Aging on Adipose Function and Adipokine Synthesis.
Peter Mancuso, Benjamin Bouchard. Front Endocrinol (Lausanne) 2019
47
12

Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.
Marissa J Schafer, Thomas A White, Glenda Evans, Jason M Tonne, Grace C Verzosa, Michael B Stout, Daniel L Mazula, Allyson K Palmer, Darren J Baker, Michael D Jensen,[...]. Diabetes 2016
103
6

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.
Thomas Kuilman, Chrysiis Michaloglou, Liesbeth C W Vredeveld, Sirith Douma, Remco van Doorn, Christophe J Desmet, Lucien A Aarden, Wolter J Mooi, Daniel S Peeper. Cell 2008
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.