Nanxin Li, Boyoung Lee, Rong-Jian Liu, Mounira Banasr, Jason M Dwyer, Masaaki Iwata, Xiao-Yuan Li, George Aghajanian, Ronald S Duman. Science 2010
Times Cited: 1607
Times Cited: 1607
Times Cited
Times Co-cited
Similarity
Antidepressant effects of ketamine in depressed patients.
R M Berman, A Cappiello, A Anand, D A Oren, G R Heninger, D S Charney, J H Krystal. Biol Psychiatry 2000
R M Berman, A Cappiello, A Anand, D A Oren, G R Heninger, D S Charney, J H Krystal. Biol Psychiatry 2000
37
NMDAR inhibition-independent antidepressant actions of ketamine metabolites.
Panos Zanos, Ruin Moaddel, Patrick J Morris, Polymnia Georgiou, Jonathan Fischell, Greg I Elmer, Manickavasagom Alkondon, Peixiong Yuan, Heather J Pribut, Nagendra S Singh,[...]. Nature 2016
Panos Zanos, Ruin Moaddel, Patrick J Morris, Polymnia Georgiou, Jonathan Fischell, Greg I Elmer, Manickavasagom Alkondon, Peixiong Yuan, Heather J Pribut, Nagendra S Singh,[...]. Nature 2016
34
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.
Anita E Autry, Megumi Adachi, Elena Nosyreva, Elisa S Na, Maarten F Los, Peng-fei Cheng, Ege T Kavalali, Lisa M Monteggia. Nature 2011
Anita E Autry, Megumi Adachi, Elena Nosyreva, Elisa S Na, Maarten F Los, Peng-fei Cheng, Ege T Kavalali, Lisa M Monteggia. Nature 2011
31
A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression.
Carlos A Zarate, Jaskaran B Singh, Paul J Carlson, Nancy E Brutsche, Rezvan Ameli, David A Luckenbaugh, Dennis S Charney, Husseini K Manji. Arch Gen Psychiatry 2006
Carlos A Zarate, Jaskaran B Singh, Paul J Carlson, Nancy E Brutsche, Rezvan Ameli, David A Luckenbaugh, Dennis S Charney, Husseini K Manji. Arch Gen Psychiatry 2006
30
Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation.
R N Moda-Sava, M H Murdock, P K Parekh, R N Fetcho, B S Huang, T N Huynh, J Witztum, D C Shaver, D L Rosenthal, E J Alway,[...]. Science 2019
R N Moda-Sava, M H Murdock, P K Parekh, R N Fetcho, B S Huang, T N Huynh, J Witztum, D C Shaver, D L Rosenthal, E J Alway,[...]. Science 2019
25
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.
Ronald S Duman, George K Aghajanian, Gerard Sanacora, John H Krystal. Nat Med 2016
Ronald S Duman, George K Aghajanian, Gerard Sanacora, John H Krystal. Nat Med 2016
24
Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.
Sungho Maeng, Carlos A Zarate, Jing Du, Robert J Schloesser, Joseph McCammon, Guang Chen, Husseini K Manji. Biol Psychiatry 2008
Sungho Maeng, Carlos A Zarate, Jing Du, Robert J Schloesser, Joseph McCammon, Guang Chen, Husseini K Manji. Biol Psychiatry 2008
22
Synaptic dysfunction in depression: potential therapeutic targets.
Ronald S Duman, George K Aghajanian. Science 2012
Ronald S Duman, George K Aghajanian. Science 2012
21
Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure.
Nanxin Li, Rong-Jian Liu, Jason M Dwyer, Mounira Banasr, Boyoung Lee, Hyeon Son, Xiao-Yuan Li, George Aghajanian, Ronald S Duman. Biol Psychiatry 2011
Nanxin Li, Rong-Jian Liu, Jason M Dwyer, Mounira Banasr, Boyoung Lee, Hyeon Son, Xiao-Yuan Li, George Aghajanian, Ronald S Duman. Biol Psychiatry 2011
20
Ketamine blocks bursting in the lateral habenula to rapidly relieve depression.
Yan Yang, Yihui Cui, Kangning Sang, Yiyan Dong, Zheyi Ni, Shuangshuang Ma, Hailan Hu. Nature 2018
Yan Yang, Yihui Cui, Kangning Sang, Yiyan Dong, Zheyi Ni, Shuangshuang Ma, Hailan Hu. Nature 2018
20
NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons.
Houman Homayoun, Bita Moghaddam. J Neurosci 2007
Houman Homayoun, Bita Moghaddam. J Neurosci 2007
19
16
Ketamine: A Paradigm Shift for Depression Research and Treatment.
John H Krystal, Chadi G Abdallah, Gerard Sanacora, Dennis S Charney, Ronald S Duman. Neuron 2019
John H Krystal, Chadi G Abdallah, Gerard Sanacora, Dennis S Charney, Ronald S Duman. Neuron 2019
17
BDNF release is required for the behavioral actions of ketamine.
Ashley E Lepack, Manabu Fuchikami, Jason M Dwyer, Mounira Banasr, Ronald S Duman. Int J Neuropsychopharmacol 2014
Ashley E Lepack, Manabu Fuchikami, Jason M Dwyer, Mounira Banasr, Ronald S Duman. Int J Neuropsychopharmacol 2014
15
Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin.
Chadi G Abdallah, Lynnette A Averill, Ralitza Gueorguieva, Selin Goktas, Prerana Purohit, Mohini Ranganathan, Mohamed Sherif, Kyung-Heup Ahn, Deepak Cyril D'Souza, Richard Formica,[...]. Neuropsychopharmacology 2020
Chadi G Abdallah, Lynnette A Averill, Ralitza Gueorguieva, Selin Goktas, Prerana Purohit, Mohini Ranganathan, Mohamed Sherif, Kyung-Heup Ahn, Deepak Cyril D'Souza, Richard Formica,[...]. Neuropsychopharmacology 2020
45
Disinhibition of CA1 pyramidal cells by low-dose ketamine and other antagonists with rapid antidepressant efficacy.
Allie J Widman, Lori L McMahon. Proc Natl Acad Sci U S A 2018
Allie J Widman, Lori L McMahon. Proc Natl Acad Sci U S A 2018
22
Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex.
Rong-Jian Liu, Francis S Lee, Xiao-Yuan Li, Francis Bambico, Ronald S Duman, George K Aghajanian. Biol Psychiatry 2012
Rong-Jian Liu, Francis S Lee, Xiao-Yuan Li, Francis Bambico, Ronald S Duman, George K Aghajanian. Biol Psychiatry 2012
14
GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions.
Danielle M Gerhard, Santosh Pothula, Rong-Jian Liu, Min Wu, Xiao-Yuan Li, Matthew J Girgenti, Seth R Taylor, Catharine H Duman, Eric Delpire, Marina Picciotto,[...]. J Clin Invest 2020
Danielle M Gerhard, Santosh Pothula, Rong-Jian Liu, Min Wu, Xiao-Yuan Li, Matthew J Girgenti, Seth R Taylor, Catharine H Duman, Eric Delpire, Marina Picciotto,[...]. J Clin Invest 2020
27
Ketamine-induced antidepressant effects are associated with AMPA receptors-mediated upregulation of mTOR and BDNF in rat hippocampus and prefrontal cortex.
W Zhou, N Wang, C Yang, X-M Li, Z-Q Zhou, J-J Yang. Eur Psychiatry 2014
W Zhou, N Wang, C Yang, X-M Li, Z-Q Zhou, J-J Yang. Eur Psychiatry 2014
13
Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial.
James W Murrough, Dan V Iosifescu, Lee C Chang, Rayan K Al Jurdi, Charles E Green, Andrew M Perez, Syed Iqbal, Sarah Pillemer, Alexandra Foulkes, Asim Shah,[...]. Am J Psychiatry 2013
James W Murrough, Dan V Iosifescu, Lee C Chang, Rayan K Al Jurdi, Charles E Green, Andrew M Perez, Syed Iqbal, Sarah Pillemer, Alexandra Foulkes, Asim Shah,[...]. Am J Psychiatry 2013
13
Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.
Panos Zanos, Ruin Moaddel, Patrick J Morris, Lace M Riggs, Jaclyn N Highland, Polymnia Georgiou, Edna F R Pereira, Edson X Albuquerque, Craig J Thomas, Carlos A Zarate,[...]. Pharmacol Rev 2018
Panos Zanos, Ruin Moaddel, Patrick J Morris, Lace M Riggs, Jaclyn N Highland, Polymnia Georgiou, Edna F R Pereira, Edson X Albuquerque, Craig J Thomas, Carlos A Zarate,[...]. Pharmacol Rev 2018
13
R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects.
C Yang, Y Shirayama, J-c Zhang, Q Ren, W Yao, M Ma, C Dong, K Hashimoto. Transl Psychiatry 2015
C Yang, Y Shirayama, J-c Zhang, Q Ren, W Yao, M Ma, C Dong, K Hashimoto. Transl Psychiatry 2015
12
Activity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2R,6R)-hydroxynorketamine.
Kenichi Fukumoto, Manoela V Fogaça, Rong-Jian Liu, Catharine Duman, Taro Kato, Xiao-Yuan Li, Ronald S Duman. Proc Natl Acad Sci U S A 2019
Kenichi Fukumoto, Manoela V Fogaça, Rong-Jian Liu, Catharine Duman, Taro Kato, Xiao-Yuan Li, Ronald S Duman. Proc Natl Acad Sci U S A 2019
20
Efficacy and Safety of Intranasal Esketamine Adjunctive to Oral Antidepressant Therapy in Treatment-Resistant Depression: A Randomized Clinical Trial.
Ella J Daly, Jaskaran B Singh, Maggie Fedgchin, Kimberly Cooper, Pilar Lim, Richard C Shelton, Michael E Thase, Andrew Winokur, Luc Van Nueten, Husseini Manji,[...]. JAMA Psychiatry 2018
Ella J Daly, Jaskaran B Singh, Maggie Fedgchin, Kimberly Cooper, Pilar Lim, Richard C Shelton, Michael E Thase, Andrew Winokur, Luc Van Nueten, Husseini Manji,[...]. JAMA Psychiatry 2018
12
Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex.
B Moghaddam, B Adams, A Verma, D Daly. J Neurosci 1997
B Moghaddam, B Adams, A Verma, D Daly. J Neurosci 1997
12
Decreased expression of synapse-related genes and loss of synapses in major depressive disorder.
Hyo Jung Kang, Bhavya Voleti, Tibor Hajszan, Grazyna Rajkowska, Craig A Stockmeier, Pawel Licznerski, Ashley Lepack, Mahesh S Majik, Lak Shin Jeong, Mounira Banasr,[...]. Nat Med 2012
Hyo Jung Kang, Bhavya Voleti, Tibor Hajszan, Grazyna Rajkowska, Craig A Stockmeier, Pawel Licznerski, Ashley Lepack, Mahesh S Majik, Lak Shin Jeong, Mounira Banasr,[...]. Nat Med 2012
11
GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine.
Rong-Jian Liu, Manabu Fuchikami, Jason M Dwyer, Ashley E Lepack, Ronald S Duman, George K Aghajanian. Neuropsychopharmacology 2013
Rong-Jian Liu, Manabu Fuchikami, Jason M Dwyer, Ashley E Lepack, Ronald S Duman, George K Aghajanian. Neuropsychopharmacology 2013
11
The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects.
Chadi G Abdallah, Henk M De Feyter, Lynnette A Averill, Lihong Jiang, Christopher L Averill, Golam M I Chowdhury, Prerana Purohit, Robin A de Graaf, Irina Esterlis, Christoph Juchem,[...]. Neuropsychopharmacology 2018
Chadi G Abdallah, Henk M De Feyter, Lynnette A Averill, Lihong Jiang, Christopher L Averill, Golam M I Chowdhury, Prerana Purohit, Robin A de Graaf, Irina Esterlis, Christoph Juchem,[...]. Neuropsychopharmacology 2018
18
GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine.
Oliver H Miller, Lingling Yang, Chih-Chieh Wang, Elizabeth A Hargroder, Yihui Zhang, Eric Delpire, Benjamin J Hall. Elife 2014
Oliver H Miller, Lingling Yang, Chih-Chieh Wang, Elizabeth A Hargroder, Yihui Zhang, Eric Delpire, Benjamin J Hall. Elife 2014
11
Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression.
Hiroyuki Koike, Michihiko Iijima, Shigeyuki Chaki. Behav Brain Res 2011
Hiroyuki Koike, Michihiko Iijima, Shigeyuki Chaki. Behav Brain Res 2011
10
A neurotrophic model for stress-related mood disorders.
Ronald S Duman, Lisa M Monteggia. Biol Psychiatry 2006
Ronald S Duman, Lisa M Monteggia. Biol Psychiatry 2006
10
Functional antagonists at the NMDA receptor complex exhibit antidepressant actions.
R Trullas, P Skolnick. Eur J Pharmacol 1990
R Trullas, P Skolnick. Eur J Pharmacol 1990
10
Ketamine and rapid-acting antidepressants: a new era in the battle against depression and suicide.
Ronald S Duman. F1000Res 2018
Ronald S Duman. F1000Res 2018
10
Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects.
G M I Chowdhury, J Zhang, M Thomas, M Banasr, X Ma, B Pittman, L Bristow, E Schaeffer, R S Duman, D L Rothman,[...]. Mol Psychiatry 2017
G M I Chowdhury, J Zhang, M Thomas, M Banasr, X Ma, B Pittman, L Bristow, E Schaeffer, R S Duman, D L Rothman,[...]. Mol Psychiatry 2017
10
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Adriana Feder, Michael K Parides, James W Murrough, Andrew M Perez, Julia E Morgan, Shireen Saxena, Katherine Kirkwood, Marije Aan Het Rot, Kyle A B Lapidus, Le-Ben Wan,[...]. JAMA Psychiatry 2014
Adriana Feder, Michael K Parides, James W Murrough, Andrew M Perez, Julia E Morgan, Shireen Saxena, Katherine Kirkwood, Marije Aan Het Rot, Kyle A B Lapidus, Le-Ben Wan,[...]. JAMA Psychiatry 2014
10
(2R,6R)-hydroxynorketamine exerts mGlu2 receptor-dependent antidepressant actions.
Panos Zanos, Jaclyn N Highland, Brent W Stewart, Polymnia Georgiou, Carleigh E Jenne, Jacqueline Lovett, Patrick J Morris, Craig J Thomas, Ruin Moaddel, Carlos A Zarate,[...]. Proc Natl Acad Sci U S A 2019
Panos Zanos, Jaclyn N Highland, Brent W Stewart, Polymnia Georgiou, Carleigh E Jenne, Jacqueline Lovett, Patrick J Morris, Craig J Thomas, Ruin Moaddel, Carlos A Zarate,[...]. Proc Natl Acad Sci U S A 2019
20
The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis.
Samuel T Wilkinson, Elizabeth D Ballard, Michael H Bloch, Sanjay J Mathew, James W Murrough, Adriana Feder, Peter Sos, Gang Wang, Carlos A Zarate, Gerard Sanacora. Am J Psychiatry 2018
Samuel T Wilkinson, Elizabeth D Ballard, Michael H Bloch, Sanjay J Mathew, James W Murrough, Adriana Feder, Peter Sos, Gang Wang, Carlos A Zarate, Gerard Sanacora. Am J Psychiatry 2018
9
Signaling pathways underlying the rapid antidepressant actions of ketamine.
Ronald S Duman, Nanxin Li, Rong-Jian Liu, Vanja Duric, George Aghajanian. Neuropharmacology 2012
Ronald S Duman, Nanxin Li, Rong-Jian Liu, Vanja Duric, George Aghajanian. Neuropharmacology 2012
9
Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics.
Chadi G Abdallah, Gerard Sanacora, Ronald S Duman, John H Krystal. Annu Rev Med 2015
Chadi G Abdallah, Gerard Sanacora, Ronald S Duman, John H Krystal. Annu Rev Med 2015
9
Effects of intravenous ketamine on explicit and implicit measures of suicidality in treatment-resistant depression.
Rebecca B Price, Matthew K Nock, Dennis S Charney, Sanjay J Mathew. Biol Psychiatry 2009
Rebecca B Price, Matthew K Nock, Dennis S Charney, Sanjay J Mathew. Biol Psychiatry 2009
9
Requirement of AMPA receptor stimulation for the sustained antidepressant activity of ketamine and LY341495 during the forced swim test in rats.
Hiroyuki Koike, Shigeyuki Chaki. Behav Brain Res 2014
Hiroyuki Koike, Shigeyuki Chaki. Behav Brain Res 2014
9
Optogenetic stimulation of medial prefrontal cortex Drd1 neurons produces rapid and long-lasting antidepressant effects.
Brendan D Hare, Ryota Shinohara, Rong Jian Liu, Santosh Pothula, Ralph J DiLeone, Ronald S Duman. Nat Commun 2019
Brendan D Hare, Ryota Shinohara, Rong Jian Liu, Santosh Pothula, Ralph J DiLeone, Ronald S Duman. Nat Commun 2019
14
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism.
Nolan R Williams, Boris D Heifets, Christine Blasey, Keith Sudheimer, Jaspreet Pannu, Heather Pankow, Jessica Hawkins, Justin Birnbaum, David M Lyons, Carolyn I Rodriguez,[...]. Am J Psychiatry 2018
Nolan R Williams, Boris D Heifets, Christine Blasey, Keith Sudheimer, Jaspreet Pannu, Heather Pankow, Jessica Hawkins, Justin Birnbaum, David M Lyons, Carolyn I Rodriguez,[...]. Am J Psychiatry 2018
9
Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial.
Carlos A Zarate, Nancy E Brutsche, Lobna Ibrahim, Jose Franco-Chaves, Nancy Diazgranados, Anibal Cravchik, Jessica Selter, Craig A Marquardt, Victoria Liberty, David A Luckenbaugh. Biol Psychiatry 2012
Carlos A Zarate, Nancy E Brutsche, Lobna Ibrahim, Jose Franco-Chaves, Nancy Diazgranados, Anibal Cravchik, Jessica Selter, Craig A Marquardt, Victoria Liberty, David A Luckenbaugh. Biol Psychiatry 2012
9
Efficacy and Safety of Flexibly Dosed Esketamine Nasal Spray Combined With a Newly Initiated Oral Antidepressant in Treatment-Resistant Depression: A Randomized Double-Blind Active-Controlled Study.
Vanina Popova, Ella J Daly, Madhukar Trivedi, Kimberly Cooper, Rosanne Lane, Pilar Lim, Christine Mazzucco, David Hough, Michael E Thase, Richard C Shelton,[...]. Am J Psychiatry 2019
Vanina Popova, Ella J Daly, Madhukar Trivedi, Kimberly Cooper, Rosanne Lane, Pilar Lim, Christine Mazzucco, David Hough, Michael E Thase, Richard C Shelton,[...]. Am J Psychiatry 2019
9
Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines.
Farhan Ali, Danielle M Gerhard, Katherine Sweasy, Santosh Pothula, Christopher Pittenger, Ronald S Duman, Alex C Kwan. Nat Commun 2020
Farhan Ali, Danielle M Gerhard, Katherine Sweasy, Santosh Pothula, Christopher Pittenger, Ronald S Duman, Alex C Kwan. Nat Commun 2020
29
Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments.
Ronald S Duman, Gerard Sanacora, John H Krystal. Neuron 2019
Ronald S Duman, Gerard Sanacora, John H Krystal. Neuron 2019
8
Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses.
Bhavya Voleti, Andrea Navarria, Rong-Jian Liu, Mounira Banasr, Nanxin Li, Rose Terwilliger, Gerard Sanacora, Tore Eid, George Aghajanian, Ronald S Duman. Biol Psychiatry 2013
Bhavya Voleti, Andrea Navarria, Rong-Jian Liu, Mounira Banasr, Nanxin Li, Rose Terwilliger, Gerard Sanacora, Tore Eid, George Aghajanian, Ronald S Duman. Biol Psychiatry 2013
8
Fast-acting antidepressants rapidly stimulate ERK signaling and BDNF release in primary neuronal cultures.
Ashley E Lepack, Eunyoung Bang, Boyoung Lee, Jason M Dwyer, Ronald S Duman. Neuropharmacology 2016
Ashley E Lepack, Eunyoung Bang, Boyoung Lee, Jason M Dwyer, Ronald S Duman. Neuropharmacology 2016
10
Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions.
Manabu Fuchikami, Alexandra Thomas, Rongjian Liu, Eric S Wohleb, Benjamin B Land, Ralph J DiLeone, George K Aghajanian, Ronald S Duman. Proc Natl Acad Sci U S A 2015
Manabu Fuchikami, Alexandra Thomas, Rongjian Liu, Eric S Wohleb, Benjamin B Land, Ralph J DiLeone, George K Aghajanian, Ronald S Duman. Proc Natl Acad Sci U S A 2015
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.