A citation-based method for searching scientific literature

Andrew C Elden, Hyung-Jun Kim, Michael P Hart, Alice S Chen-Plotkin, Brian S Johnson, Xiaodong Fang, Maria Armakola, Felix Geser, Robert Greene, Min Min Lu, Arun Padmanabhan, Dana Clay-Falcone, Leo McCluskey, Lauren Elman, Denise Juhr, Peter J Gruber, Udo Rüb, Georg Auburger, John Q Trojanowski, Virginia M-Y Lee, Vivianna M Van Deerlin, Nancy M Bonini, Aaron D Gitler. Nature 2010
Times Cited: 737

List of co-cited articles
1730 articles co-cited >1

Times Cited
  Times     Co-cited

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011

Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice.
Lindsay A Becker, Brenda Huang, Gregor Bieri, Rosanna Ma, David A Knowles, Paymaan Jafar-Nejad, James Messing, Hong Joo Kim, Armand Soriano, Georg Auburger,[...]. Nature 2017

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Jemeen Sreedharan, Ian P Blair, Vineeta B Tripathi, Xun Hu, Caroline Vance, Boris Rogelj, Steven Ackerley, Jennifer C Durnall, Kelly L Williams, Emanuele Buratti,[...]. Science 2008

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.
T J Kwiatkowski, D A Bosco, A L Leclerc, E Tamrazian, C R Vanderburg, C Russ, A Davis, J Gilchrist, E J Kasarskis, T Munsat,[...]. Science 2009

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.
Ke Zhang, Christopher J Donnelly, Aaron R Haeusler, Jonathan C Grima, James B Machamer, Peter Steinwald, Elizabeth L Daley, Sean J Miller, Kathleen M Cunningham, Svetlana Vidensky,[...]. Nature 2015

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS.
Hong Joo Kim, Nam Chul Kim, Yong-Dong Wang, Emily A Scarborough, Jennifer Moore, Zamia Diaz, Kyle S MacLea, Brian Freibaum, Songqing Li, Amandine Molliex,[...]. Nature 2013

Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis.
Shuo-Chien Ling, Magdalini Polymenidou, Don W Cleveland. Neuron 2013

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6.
Caroline Vance, Boris Rogelj, Tibor Hortobágyi, Kurt J De Vos, Agnes Lumi Nishimura, Jemeen Sreedharan, Xun Hu, Bradley Smith, Deborah Ruddy, Paul Wright,[...]. Science 2009

Decoding ALS: from genes to mechanism.
J Paul Taylor, Robert H Brown, Don W Cleveland. Nature 2016

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993

Stress granules as crucibles of ALS pathogenesis.
Yun R Li, Oliver D King, James Shorter, Aaron D Gitler. J Cell Biol 2013

Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules.
Ute Nonhoff, Markus Ralser, Franziska Welzel, Ilaria Piccini, Daniela Balzereit, Marie-Laure Yaspo, Hans Lehrach, Sylvia Krobitsch. Mol Biol Cell 2007

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.
Brian D Freibaum, Yubing Lu, Rodrigo Lopez-Gonzalez, Nam Chul Kim, Sandra Almeida, Kyung-Ha Lee, Nisha Badders, Marc Valentine, Bruce L Miller, Philip C Wong,[...]. Nature 2015

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Ian R Mackenzie, Alexandra M Nicholson, Mohona Sarkar, James Messing, Maria D Purice, Cyril Pottier, Kavya Annu, Matt Baker, Ralph B Perkerson, Aishe Kurti,[...]. Neuron 2017

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.
Magdalini Polymenidou, Clotilde Lagier-Tourenne, Kasey R Hutt, Stephanie C Huelga, Jacqueline Moran, Tiffany Y Liang, Shuo-Chien Ling, Eveline Sun, Edward Wancewicz, Curt Mazur,[...]. Nat Neurosci 2011

Amyotrophic Lateral Sclerosis.
Robert H Brown, Ammar Al-Chalabi. N Engl J Med 2017

Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death.
Fatima Gasset-Rosa, Shan Lu, Haiyang Yu, Cong Chen, Ze'ev Melamed, Lin Guo, James Shorter, Sandrine Da Cruz, Don W Cleveland. Neuron 2019

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis.
Edor Kabashi, Paul N Valdmanis, Patrick Dion, Dan Spiegelman, Brendan J McConkey, Christine Vande Velde, Jean-Pierre Bouchard, Lucette Lacomblez, Ksenia Pochigaeva, Francois Salachas,[...]. Nat Genet 2008

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Avinash Patel, Hyun O Lee, Louise Jawerth, Shovamayee Maharana, Marcus Jahnel, Marco Y Hein, Stoyno Stoynov, Julia Mahamid, Shambaditya Saha, Titus M Franzmann,[...]. Cell 2015

Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization.
Amandine Molliex, Jamshid Temirov, Jihun Lee, Maura Coughlin, Anderson P Kanagaraj, Hong Joo Kim, Tanja Mittag, J Paul Taylor. Cell 2015

Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue.
Liqun Liu-Yesucevitz, Aylin Bilgutay, Yong-Jie Zhang, Tara Vanderweyde, Allison Citro, Tapan Mehta, Nava Zaarur, Ann McKee, Robert Bowser, Michael Sherman,[...]. PLoS One 2010

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.
Jacob R Mann, Amanda M Gleixner, Jocelyn C Mauna, Edward Gomes, Michael R DeChellis-Marks, Patrick G Needham, Katie E Copley, Bryan Hurtle, Bede Portz, Noah J Pyles,[...]. Neuron 2019

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.
Kyung-Ha Lee, Peipei Zhang, Hong Joo Kim, Diana M Mitrea, Mohona Sarkar, Brian D Freibaum, Jaclyn Cika, Maura Coughlin, James Messing, Amandine Molliex,[...]. Cell 2016

RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention.
Christopher J Donnelly, Ping-Wu Zhang, Jacqueline T Pham, Aaron R Haeusler, Nipun A Mistry, Svetlana Vidensky, Elizabeth L Daley, Erin M Poth, Benjamin Hoover, Daniel M Fines,[...]. Neuron 2013

Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2.
S M Pulst, A Nechiporuk, T Nechiporuk, S Gispert, X N Chen, I Lopes-Cendes, S Pearlman, S Starkman, G Orozco-Diaz, A Lunkes,[...]. Nat Genet 1996

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.
Sarah Mizielinska, Sebastian Grönke, Teresa Niccoli, Charlotte E Ridler, Emma L Clayton, Anny Devoy, Thomas Moens, Frances E Norona, Ione O C Woollacott, Julian Pietrzyk,[...]. Science 2014

Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models.
Hyung-Jun Kim, Alya R Raphael, Eva S LaDow, Leeanne McGurk, Ross A Weber, John Q Trojanowski, Virginia M-Y Lee, Steven Finkbeiner, Aaron D Gitler, Nancy M Bonini. Nat Genet 2014

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.
Saumya Jain, Joshua R Wheeler, Robert W Walters, Anurag Agrawal, Anthony Barsic, Roy Parker. Cell 2016

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.
Elizabeth T Cirulli, Brittany N Lasseigne, Slavé Petrovski, Peter C Sapp, Patrick A Dion, Claire S Leblond, Julien Couthouis, Yi-Fan Lu, Quanli Wang, Brian J Krueger,[...]. Science 2015

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.
Aude Nicolas, Kevin P Kenna, Alan E Renton, Nicola Ticozzi, Faraz Faghri, Ruth Chia, Janice A Dominov, Brendan J Kenna, Mike A Nalls, Pamela Keagle,[...]. Neuron 2018

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia.
Han-Xiang Deng, Wenjie Chen, Seong-Tshool Hong, Kym M Boycott, George H Gorrie, Nailah Siddique, Yi Yang, Faisal Fecto, Yong Shi, Hong Zhai,[...]. Nature 2011

RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia.
Tao Zu, Yuanjing Liu, Monica Bañez-Coronel, Tammy Reid, Olga Pletnikova, Jada Lewis, Timothy M Miller, Matthew B Harms, Annet E Falchook, S H Subramony,[...]. Proc Natl Acad Sci U S A 2013

State of play in amyotrophic lateral sclerosis genetics.
Alan E Renton, Adriano Chiò, Bryan J Traynor. Nat Neurosci 2014

C9orf72-mediated ALS and FTD: multiple pathways to disease.
Rubika Balendra, Adrian M Isaacs. Nat Rev Neurol 2018

Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study.
Elisa Majounie, Alan E Renton, Kin Mok, Elise G P Dopper, Adrian Waite, Sara Rollinson, Adriano Chiò, Gabriella Restagno, Nayia Nicolaou, Javier Simon-Sanchez,[...]. Lancet Neurol 2012

The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS.
Kohji Mori, Shih-Ming Weng, Thomas Arzberger, Stephanie May, Kristin Rentzsch, Elisabeth Kremmer, Bettina Schmid, Hans A Kretzschmar, Marc Cruts, Christine Van Broeckhoven,[...]. Science 2013

Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.
Lin Guo, Hong Joo Kim, Hejia Wang, John Monaghan, Fernande Freyermuth, Julie C Sung, Kevin O'Donovan, Charlotte M Fare, Zamia Diaz, Nikita Singh,[...]. Cell 2018

Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.
Nael H Alami, Rebecca B Smith, Monica A Carrasco, Luis A Williams, Christina S Winborn, Steve S W Han, Evangelos Kiskinis, Brett Winborn, Brian D Freibaum, Anderson Kanagaraj,[...]. Neuron 2014

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.
Ana Jovičić, Jerome Mertens, Steven Boeynaems, Elke Bogaert, Noori Chai, Shizuka B Yamada, Joseph W Paul, Shuying Sun, Joseph R Herdy, Gregor Bieri,[...]. Nat Neurosci 2015

Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Mario Hofweber, Saskia Hutten, Benjamin Bourgeois, Emil Spreitzer, Annika Niedner-Boblenz, Martina Schifferer, Marc-David Ruepp, Mikael Simons, Dierk Niessing, Tobias Madl,[...]. Cell 2018

Stress Granule Assembly Disrupts Nucleocytoplasmic Transport.
Ke Zhang, J Gavin Daigle, Kathleen M Cunningham, Alyssa N Coyne, Kai Ruan, Jonathan C Grima, Kelly E Bowen, Harsh Wadhwa, Peiguo Yang, Frank Rigo,[...]. Cell 2018

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.
Clotilde Lagier-Tourenne, Magdalini Polymenidou, Kasey R Hutt, Anthony Q Vu, Michael Baughn, Stephanie C Huelga, Kevin M Clutario, Shuo-Chien Ling, Tiffany Y Liang, Curt Mazur,[...]. Nat Neurosci 2012

Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization.
Leeanne McGurk, Edward Gomes, Lin Guo, Jelena Mojsilovic-Petrovic, Van Tran, Robert G Kalb, James Shorter, Nancy M Bonini. Mol Cell 2018

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.
Wouter van Rheenen, Aleksey Shatunov, Annelot M Dekker, Russell L McLaughlin, Frank P Diekstra, Sara L Pulit, Rick A A van der Spek, Urmo Võsa, Simone de Jong, Matthew R Robinson,[...]. Nat Genet 2016

Direct binding of Ataxin-2 to distinct elements in 3' UTRs promotes mRNA stability and protein expression.
Moe Yokoshi, Quan Li, Munetaka Yamamoto, Hitomi Okada, Yutaka Suzuki, Yukio Kawahara. Mol Cell 2014

TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity.
Brian S Johnson, David Snead, Jonathan J Lee, J Michael McCaffery, James Shorter, Aaron D Gitler. J Biol Chem 2009

Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion.
Dhruv Sareen, Jacqueline G O'Rourke, Pratap Meera, A K M G Muhammad, Sharday Grant, Megan Simpkinson, Shaughn Bell, Sharon Carmona, Loren Ornelas, Anais Sahabian,[...]. Sci Transl Med 2013

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.
Dorothee Dormann, Ramona Rodde, Dieter Edbauer, Eva Bentmann, Ingeborg Fischer, Alexander Hruscha, Manuel E Than, Ian R A Mackenzie, Anja Capell, Bettina Schmid,[...]. EMBO J 2010

Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.