Feng Shao, Xiao Han, Nanxin Li, Weiwen Wang. Eur J Pharmacol 2010
Times Cited: 7
Times Cited: 7
Times Cited
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Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial.
Sandeep T Patil, Lu Zhang, Ferenc Martenyi, Stephen L Lowe, Kimberley A Jackson, Boris V Andreev, Alla S Avedisova, Leonid M Bardenstein, Issak Y Gurovich, Margarita A Morozova,[...]. Nat Med 2007
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Glutamatergic (N-methyl-D-aspartate receptor) hypofrontality in schizophrenia: too little juice or a miswired brain?
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NMDA receptor hypofunction model of schizophrenia.
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The difference in effect of mGlu2/3 and mGlu5 receptor agonists on cognitive impairment induced by MK-801.
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Karel Vales, Jan Svoboda, Kristina Benkovicova, Vera Bubenikova-Valesova, Ales Stuchlik. Eur J Pharmacol 2010
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Therapeutic effects of metabotropic glutamate receptor 5 positive allosteric modulator CDPPB on phencyclidine-induced cognitive deficits in mice.
Mao Horio, Yuko Fujita, Kenji Hashimoto. Fundam Clin Pharmacol 2013
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Dopamine is not required for the hyperlocomotor response to NMDA receptor antagonists.
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Enhancement of social novelty discrimination by positive allosteric modulators at metabotropic glutamate 5 receptors: adolescent administration prevents adult-onset deficits induced by neonatal treatment with phencyclidine.
Nicholas E Clifton, Nadège Morisot, Sylvie Girardon, Mark J Millan, Florence Loiseau. Psychopharmacology (Berl) 2013
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The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity.
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Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm.
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A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models.
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Comparison of the mGlu(5) receptor positive allosteric modulator ADX47273 and the mGlu(2/3) receptor agonist LY354740 in tests for antipsychotic-like activity.
Chantal Schlumberger, Małgorzata Pietraszek, Andreas Gravius, Kai-Uwe Klein, Sergio Greco, Lorenzo Morè, Wojciech Danysz. Eur J Pharmacol 2009
Chantal Schlumberger, Małgorzata Pietraszek, Andreas Gravius, Kai-Uwe Klein, Sergio Greco, Lorenzo Morè, Wojciech Danysz. Eur J Pharmacol 2009
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Recent advances in the phencyclidine model of schizophrenia.
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Homer 1a gene expression modulation by antipsychotic drugs: involvement of the glutamate metabotropic system and effects of D-cycloserine.
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Functional interactions between presynaptic NMDA receptors and metabotropic glutamate receptors co-expressed on rat and human noradrenergic terminals.
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The mGlu₅ positive allosteric modulator LSN2463359 differentially modulates motor, instrumental and cognitive effects of NMDA receptor antagonists in the rat.
Francois Gastambide, Gary Gilmour, Trevor W Robbins, Mark D Tricklebank. Neuropharmacology 2013
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Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice.
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28
MK-801 produces a deficit in sucrose preference that is reversed by clozapine, D-serine, and the metabotropic glutamate 5 receptor positive allosteric modulator CDPPB: relevance to negative symptoms associated with schizophrenia?
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28
mGluR5, but not mGluR1, antagonist modifies MK-801-induced locomotor activity and deficit of prepulse inhibition.
M Pietraszek, A Gravius, D Schäfer, T Weil, D Trifanova, W Danysz. Neuropharmacology 2005
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Selective remediation of reversal learning deficits in the neurodevelopmental MAM model of schizophrenia by a novel mGlu5 positive allosteric modulator.
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Metabotropic glutamate subtype 5 receptors modulate fear-conditioning induced enhancement of prepulse inhibition in rats.
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Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release.
Houman Homayoun, Mark R Stefani, Barbara W Adams, Gilles D Tamagan, Bita Moghaddam. Neuropsychopharmacology 2004
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Comparing protein abundance and mRNA expression levels on a genomic scale.
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Catching up on schizophrenia: natural history and neurobiology.
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NMDA-induced phosphorylation and regulation of mGluR5.
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28
Effects of a positive allosteric modulator of mGluR5 ADX47273 on conditioned avoidance response and PCP-induced hyperlocomotion in the rat as models for schizophrenia.
Chantal Schlumberger, Małgorzata Pietraszek, Andreas Gravius, Wojciech Danysz. Pharmacol Biochem Behav 2010
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28
In vitro characterisation of the novel positive allosteric modulators of the mGlu₅ receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat.
Gary Gilmour, Lisa M Broad, Keith A Wafford, Thomas Britton, Ellen M Colvin, Adam Fivush, Francois Gastambide, Brian Getman, Beverly A Heinz, Andrew P McCarthy,[...]. Neuropharmacology 2013
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28
Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-D-aspartic acid receptor up-regulation.
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28
Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition.
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28
Glutamatergic mechanisms in schizophrenia.
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28
Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP.
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Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade.
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28
Addressing side effects from antipsychotic treatment in schizophrenia.
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Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action.
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The "two-headed" latent inhibition model of schizophrenia: modeling positive and negative symptoms and their treatment.
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28
Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.
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Effects of microinjections of apomorphine and haloperidol into the inferior colliculus on the latent inhibition of the conditioned emotional response.
Liana L Melo, Ellen C H M Pereira, Cássia H Pagini, Norberto C Coimbra, Marcus L Brandão, Elenice A M Ferrari. Exp Neurol 2009
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The M₁/M₄ preferring agonist xanomeline reverses amphetamine-, MK801- and scopolamine-induced abnormalities of latent inhibition: putative efficacy against positive, negative and cognitive symptoms in schizophrenia.
Segev Barak, Ina Weiner. Int J Neuropsychopharmacol 2011
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28
28
Glycine reuptake inhibitor RG1678: a pharmacologic characterization of an investigational agent for the treatment of schizophrenia.
Daniela Alberati, Jean-Luc Moreau, Judith Lengyel, Nicole Hauser, Roland Mory, Edilio Borroni, Emmanuel Pinard, Frederic Knoflach, Götz Schlotterbeck, Dominik Hainzl,[...]. Neuropharmacology 2012
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Animal behavior models of the mechanisms underlying antipsychotic atypicality.
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Influence of social isolation in the rat on serotonergic function and memory--relevance to models of schizophrenia and the role of 5-HT₆ receptors.
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The dopamine hypothesis of schizophrenia: version III--the final common pathway.
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Neural mechanisms of addiction: the role of reward-related learning and memory.
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GABAergic interneuron origin of schizophrenia pathophysiology.
Kazu Nakazawa, Veronika Zsiros, Zhihong Jiang, Kazuhito Nakao, Stefan Kolata, Shuqin Zhang, Juan E Belforte. Neuropharmacology 2012
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14
The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety.
Chris S Busse, Jesse Brodkin, David Tattersall, Jeffery J Anderson, Noelle Warren, Lida Tehrani, Linda J Bristow, Mark A Varney, Nicholas D P Cosford. Neuropsychopharmacology 2004
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14
The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia.
R S Devon, S Anderson, P W Teague, W J Muir, V Murray, A J Pelosi, D H Blackwood, D J Porteous. Mol Psychiatry 2001
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14
Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus.
Jason M Uslaner, Sophie Parmentier-Batteur, Rosemarie B Flick, Nathaniel O Surles, June S H Lam, Caitlyn H McNaughton, Marlene A Jacobson, Pete H Hutson. Neuropharmacology 2009
Jason M Uslaner, Sophie Parmentier-Batteur, Rosemarie B Flick, Nathaniel O Surles, June S H Lam, Caitlyn H McNaughton, Marlene A Jacobson, Pete H Hutson. Neuropharmacology 2009
14
The antianxiety-like effects of antagonists of group I and agonists of group II and III metabotropic glutamate receptors after intrahippocampal administration.
E Tatarczyńska, A Kłodzińska, B Kroczka, E Chojnacka-Wójcik, A Pilc. Psychopharmacology (Berl) 2001
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14
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.