A citation-based method for searching scientific literature

Leonie Unterholzner, Sinead E Keating, Marcin Baran, Kristy A Horan, Søren B Jensen, Shruti Sharma, Cherilyn M Sirois, Tengchuan Jin, Eicke Latz, T Sam Xiao, Katherine A Fitzgerald, Søren R Paludan, Andrew G Bowie. Nat Immunol 2010
Times Cited: 1032







List of co-cited articles
1085 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
44

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.
Akinori Takaoka, Zhichao Wang, Myoung Kwon Choi, Hideyuki Yanai, Hideo Negishi, Tatsuma Ban, Yan Lu, Makoto Miyagishi, Tatsuhiko Kodama, Kenya Honda,[...]. Nature 2007
29

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis, Franz Bauernfeind, Gabor Horvath, Daniel R Caffrey, Eicke Latz, Katherine A Fitzgerald. Nature 2009
28

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells.
Zhiqiang Zhang, Bin Yuan, Musheng Bao, Ning Lu, Taeil Kim, Yong-Jun Liu. Nat Immunol 2011
544
26

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J Chen. Science 2013
23

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection.
Nagaraj Kerur, Mohanan Valiya Veettil, Neelam Sharma-Walia, Virginie Bottero, Sathish Sadagopan, Pushpalatha Otageri, Bala Chandran. Cell Host Microbe 2011
451
23



AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA.
Teresa Fernandes-Alnemri, Je-Wook Yu, Pinaki Datta, Jianghong Wu, Emad S Alnemri. Nature 2009
20

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J Chen. Science 2013
585
20

IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes.
Jessica F Almine, Craig A J O'Hare, Gillian Dunphy, Ismar R Haga, Rangeetha J Naik, Abdelmadjid Atrih, Dympna J Connolly, Jordan Taylor, Ian R Kelsall, Andrew G Bowie,[...]. Nat Commun 2017
158
19


Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses.
Daxing Gao, Jiaxi Wu, You-Tong Wu, Fenghe Du, Chukwuemika Aroh, Nan Yan, Lijun Sun, Zhijian J Chen. Science 2013
606
16

Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
Haipeng Liu, Haiping Zhang, Xiangyang Wu, Dapeng Ma, Juehui Wu, Lin Wang, Yan Jiang, Yiyan Fei, Chenggang Zhu, Rong Tan,[...]. Nature 2018
199
16

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.
Tilmann Bürckstümmer, Christoph Baumann, Stephan Blüml, Evelyn Dixit, Gerhard Dürnberger, Hannah Jahn, Melanie Planyavsky, Martin Bilban, Jacques Colinge, Keiryn L Bennett,[...]. Nat Immunol 2009
721
15

A Toll-like receptor recognizes bacterial DNA.
H Hemmi, O Takeuchi, T Kawai, T Kaisho, S Sato, H Sanjo, M Matsumoto, K Hoshino, H Wagner, K Takeda,[...]. Nature 2000
15

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.
Andrea Ablasser, Franz Bauernfeind, Gunther Hartmann, Eicke Latz, Katherine A Fitzgerald, Veit Hornung. Nat Immunol 2009
587
15

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.
Andrea Ablasser, Marion Goldeck, Taner Cavlar, Tobias Deimling, Gregor Witte, Ingo Röhl, Karl-Peter Hopfner, Janos Ludwig, Veit Hornung. Nature 2013
713
15

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.
Bo Zhong, Yan Yang, Shu Li, Yan-Yi Wang, Ying Li, Feici Diao, Caoqi Lei, Xiao He, Lu Zhang, Po Tien,[...]. Immunity 2008
852
15


Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.
Gillian Dunphy, Sinéad M Flannery, Jessica F Almine, Dympna J Connolly, Christina Paulus, Kasper L Jønsson, Martin R Jakobsen, Michael M Nevels, Andrew G Bowie, Leonie Unterholzner. Mol Cell 2018
170
14

Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.
Tengchuan Jin, Andrew Perry, Jiansheng Jiang, Patrick Smith, James A Curry, Leonie Unterholzner, Zhaozhao Jiang, Gabor Horvath, Vijay A Rathinam, Ricky W Johnstone,[...]. Immunity 2012
301
14

IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV.
Kathryn M Monroe, Zhiyuan Yang, Jeffrey R Johnson, Xin Geng, Gilad Doitsh, Nevan J Krogan, Warner C Greene. Science 2014
318
13

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses.
Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa, Noriaki Shinobu, Tadaatsu Imaizumi, Makoto Miyagishi, Kazunari Taira, Shizuo Akira, Takashi Fujita. Nat Immunol 2004
13

cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Liudmila Andreeva, Björn Hiller, Dirk Kostrewa, Charlotte Lässig, Carina C de Oliveira Mann, David Jan Drexler, Andreas Maiser, Moritz Gaidt, Heinrich Leonhardt, Veit Hornung,[...]. Nature 2017
170
13


Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses.
Mairaj Ahmed Ansari, Sujoy Dutta, Mohanan Valiya Veettil, Dipanjan Dutta, Jawed Iqbal, Binod Kumar, Arunava Roy, Leela Chikoti, Vivek Vikram Singh, Bala Chandran. PLoS Pathog 2015
79
16

Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16.
Tuo Li, Benjamin A Diner, Jin Chen, Ileana M Cristea. Proc Natl Acad Sci U S A 2012
202
13

cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.
Megan H Orzalli, Nicole M Broekema, Benjamin A Diner, Dustin C Hancks, Nels C Elde, Ileana M Cristea, David M Knipe. Proc Natl Acad Sci U S A 2015
153
12

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses.
Hiroki Kato, Osamu Takeuchi, Shintaro Sato, Mitsutoshi Yoneyama, Masahiro Yamamoto, Kosuke Matsui, Satoshi Uematsu, Andreas Jung, Taro Kawai, Ken J Ishii,[...]. Nature 2006
11

Structural mechanism of cytosolic DNA sensing by cGAS.
Filiz Civril, Tobias Deimling, Carina C de Oliveira Mann, Andrea Ablasser, Manuela Moldt, Gregor Witte, Veit Hornung, Karl-Peter Hopfner. Nature 2013
356
11

DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking.
Takeshi Kondo, Junya Kobayashi, Tatsuya Saitoh, Kenta Maruyama, Ken J Ishii, Glen N Barber, Kenshi Komatsu, Shizuo Akira, Taro Kawai. Proc Natl Acad Sci U S A 2013
215
11

DNA-PK is a DNA sensor for IRF-3-dependent innate immunity.
Brian J Ferguson, Daniel S Mansur, Nicholas E Peters, Hongwei Ren, Geoffrey L Smith. Elife 2012
229
11

Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.
Qi Chen, Lijun Sun, Zhijian J Chen. Nat Immunol 2016
696
11

IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP.
K L Jønsson, A Laustsen, C Krapp, K A Skipper, K Thavachelvam, D Hotter, J H Egedal, M Kjolby, P Mohammadi, T Prabakaran,[...]. Nat Commun 2017
141
11

Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy.
Seamus R Morrone, Tao Wang, Leeza M Constantoulakis, Richard M Hooy, Michael J Delannoy, Jungsan Sohn. Proc Natl Acad Sci U S A 2014
112
11

5'-Triphosphate RNA is the ligand for RIG-I.
Veit Hornung, Jana Ellegast, Sarah Kim, Krzysztof Brzózka, Andreas Jung, Hiroki Kato, Hendrik Poeck, Shizuo Akira, Karl-Klaus Conzelmann, Martin Schlee,[...]. Science 2006
10

HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression.
Maria H Christensen, Søren B Jensen, Juho J Miettinen, Stefanie Luecke, Thaneas Prabakaran, Line S Reinert, Thomas Mettenleiter, Zhijian J Chen, David M Knipe, Rozanne M Sandri-Goldin,[...]. EMBO J 2016
108
10

Pathogen recognition and innate immunity.
Shizuo Akira, Satoshi Uematsu, Osamu Takeuchi. Cell 2006
10

Herpes Simplex Virus 1 Tegument Protein VP22 Abrogates cGAS/STING-Mediated Antiviral Innate Immunity.
Jian Huang, Hongjuan You, Chenhe Su, Yangxin Li, Shunhua Chen, Chunfu Zheng. J Virol 2018
71
14


Immune sensing of DNA.
Søren R Paludan, Andrew G Bowie. Immunity 2013
497
10

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.
L Alexopoulou, A C Holt, R Medzhitov, R A Flavell. Nature 2001
10


Cutting edge: Ku70 is a novel cytosolic DNA sensor that induces type III rather than type I IFN.
Xing Zhang, Terrence W Brann, Ming Zhou, Jun Yang, Raphael M Oguariri, Kristy B Lidie, Hiromi Imamichi, Da-Wei Huang, Richard A Lempicki, Michael W Baseler,[...]. J Immunol 2011
150
10

Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization.
Xin Li, Chang Shu, Guanghui Yi, Catherine T Chaton, Catherine L Shelton, Jiasheng Diao, Xiaobing Zuo, C Cheng Kao, Andrew B Herr, Pingwei Li. Immunity 2013
265
10

Tight nuclear tethering of cGAS is essential for preventing autoreactivity.
Hannah E Volkman, Stephanie Cambier, Elizabeth E Gray, Daniel B Stetson. Elife 2019
78
11

Chromatin-bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death.
Hui Jiang, Xiaoyu Xue, Swarupa Panda, Ajinkya Kawale, Richard M Hooy, Fengshan Liang, Jungsan Sohn, Patrick Sung, Nelson O Gekara. EMBO J 2019
75
12

Pattern recognition receptors and inflammation.
Osamu Takeuchi, Shizuo Akira. Cell 2010
9

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation.
Siqi Liu, Xin Cai, Jiaxi Wu, Qian Cong, Xiang Chen, Tuo Li, Fenghe Du, Junyao Ren, You-Tong Wu, Nick V Grishin,[...]. Science 2015
683
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.