Heng Du, Lan Guo, Shiqiang Yan, Alexander A Sosunov, Guy M McKhann, Shirley ShiDu Yan. Proc Natl Acad Sci U S A 2010
Times Cited: 469
Times Cited: 469
Times Cited
Times Co-cited
Similarity
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
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Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
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Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease.
Marcus J Calkins, Maria Manczak, Peizhong Mao, Ulziibat Shirendeb, P Hemachandra Reddy. Hum Mol Genet 2011
Marcus J Calkins, Maria Manczak, Peizhong Mao, Ulziibat Shirendeb, P Hemachandra Reddy. Hum Mol Genet 2011
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Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins.
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
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The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae.
Camilla A Hansson Petersen, Nyosha Alikhani, Homira Behbahani, Birgitta Wiehager, Pavel F Pavlov, Irina Alafuzoff, Ville Leinonen, Akira Ito, Bengt Winblad, Elzbieta Glaser,[...]. Proc Natl Acad Sci U S A 2008
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Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease.
Casper Caspersen, Ning Wang, Jun Yao, Alexander Sosunov, Xi Chen, Joyce W Lustbader, Hong Wei Xu, David Stern, Guy McKhann, Shi Du Yan. FASEB J 2005
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Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease.
Jia Yao, Ronald W Irwin, Liqin Zhao, Jon Nilsen, Ryan T Hamilton, Roberta Diaz Brinton. Proc Natl Acad Sci U S A 2009
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Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression.
Maria Manczak, Thimmappa S Anekonda, Edward Henson, Byung S Park, Joseph Quinn, P Hemachandra Reddy. Hum Mol Genet 2006
Maria Manczak, Thimmappa S Anekonda, Edward Henson, Byung S Park, Joseph Quinn, P Hemachandra Reddy. Hum Mol Genet 2006
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Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
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ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
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Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
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Parkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brains.
Xuan Ye, Xiaqin Sun, Valentin Starovoytov, Qian Cai. Hum Mol Genet 2015
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Mitochondria and Mitochondrial Cascades in Alzheimer's Disease.
Russell H Swerdlow. J Alzheimers Dis 2018
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The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives.
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Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.
Qian Cai, Prasad Tammineni. J Alzheimers Dis 2017
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Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.
Latha Devi, Badanavalu M Prabhu, Domenico F Galati, Narayan G Avadhani, Hindupur K Anandatheerthavarada. J Neurosci 2006
Latha Devi, Badanavalu M Prabhu, Domenico F Galati, Narayan G Avadhani, Hindupur K Anandatheerthavarada. J Neurosci 2006
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Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology.
Paula I Moreira, Cristina Carvalho, Xiongwei Zhu, Mark A Smith, George Perry. Biochim Biophys Acta 2010
Paula I Moreira, Cristina Carvalho, Xiongwei Zhu, Mark A Smith, George Perry. Biochim Biophys Acta 2010
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Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms.
Jesse S Kerr, Bryan A Adriaanse, Nigel H Greig, Mark P Mattson, M Zameel Cader, Vilhelm A Bohr, Evandro F Fang. Trends Neurosci 2017
Jesse S Kerr, Bryan A Adriaanse, Nigel H Greig, Mark P Mattson, M Zameel Cader, Vilhelm A Bohr, Evandro F Fang. Trends Neurosci 2017
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Oxidative stress and mitochondrial dysfunction in Alzheimer's disease.
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Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease.
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Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration.
Zu-Hang Sheng, Qian Cai. Nat Rev Neurosci 2012
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Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics.
P Hemachandra Reddy, Raghav Tripathi, Quang Troung, Karuna Tirumala, Tejaswini P Reddy, Vishwanath Anekonda, Ulziibat P Shirendeb, Marcus J Calkins, Arubala P Reddy, Peizhong Mao,[...]. Biochim Biophys Acta 2012
P Hemachandra Reddy, Raghav Tripathi, Quang Troung, Karuna Tirumala, Tejaswini P Reddy, Vishwanath Anekonda, Ulziibat P Shirendeb, Marcus J Calkins, Arubala P Reddy, Peizhong Mao,[...]. Biochim Biophys Acta 2012
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Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.
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The amyloid hypothesis of Alzheimer's disease at 25 years.
Dennis J Selkoe, John Hardy. EMBO Mol Med 2016
Dennis J Selkoe, John Hardy. EMBO Mol Med 2016
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Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.
Maria Manczak, Byung S Park, Youngsin Jung, P Hemachandra Reddy. Neuromolecular Med 2004
Maria Manczak, Byung S Park, Youngsin Jung, P Hemachandra Reddy. Neuromolecular Med 2004
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Alterations in Mitochondrial Quality Control in Alzheimer's Disease.
Qian Cai, Prasad Tammineni. Front Cell Neurosci 2016
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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.
John Hardy, Dennis J Selkoe. Science 2002
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PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease.
Fang Du, Qing Yu, Shijun Yan, Gang Hu, Lih-Fen Lue, Douglas G Walker, Long Wu, Shi Fang Yan, Kim Tieu, Shirley ShiDu Yan. Brain 2017
Fang Du, Qing Yu, Shijun Yan, Gang Hu, Lih-Fen Lue, Douglas G Walker, Long Wu, Shi Fang Yan, Kim Tieu, Shirley ShiDu Yan. Brain 2017
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Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity.
Vincenzo Sorrentino, Mario Romani, Laurent Mouchiroud, John S Beck, Hongbo Zhang, Davide D'Amico, Norman Moullan, Francesca Potenza, Adrien W Schmid, Solène Rietsch,[...]. Nature 2017
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Mitochondrial alterations near amyloid plaques in an Alzheimer's disease mouse model.
Hong Xie, Jisong Guan, Laura A Borrelli, Jing Xu, Alberto Serrano-Pozo, Brian J Bacskai. J Neurosci 2013
Hong Xie, Jisong Guan, Laura A Borrelli, Jing Xu, Alberto Serrano-Pozo, Brian J Bacskai. J Neurosci 2013
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The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease.
Alicia M Pickrell, Richard J Youle. Neuron 2015
Alicia M Pickrell, Richard J Youle. Neuron 2015
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Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
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Mitochondrial Dysfunction and Synaptic Transmission Failure in Alzheimer's Disease.
Lan Guo, Jing Tian, Heng Du. J Alzheimers Dis 2017
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Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer's disease.
Eleanor K Pickett, Jamie Rose, Caoimhe McCrory, Chris-Anne McKenzie, Declan King, Colin Smith, Thomas H Gillingwater, Christopher M Henstridge, Tara L Spires-Jones. Acta Neuropathol 2018
Eleanor K Pickett, Jamie Rose, Caoimhe McCrory, Chris-Anne McKenzie, Declan King, Colin Smith, Thomas H Gillingwater, Christopher M Henstridge, Tara L Spires-Jones. Acta Neuropathol 2018
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Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice.
S Hauptmann, I Scherping, S Dröse, U Brandt, K L Schulz, M Jendrach, K Leuner, A Eckert, W E Müller. Neurobiol Aging 2009
S Hauptmann, I Scherping, S Dröse, U Brandt, K L Schulz, M Jendrach, K Leuner, A Eckert, W E Müller. Neurobiol Aging 2009
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Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models.
Louise Hedskog, Catarina Moreira Pinho, Riccardo Filadi, Annica Rönnbäck, Laura Hertwig, Birgitta Wiehager, Pia Larssen, Sandra Gellhaar, Anna Sandebring, Marie Westerlund,[...]. Proc Natl Acad Sci U S A 2013
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Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice.
Della C David, Susanne Hauptmann, Isabel Scherping, Katrin Schuessel, Uta Keil, Patrizia Rizzu, Rivka Ravid, Stefan Dröse, Ulrich Brandt, Walter E Müller,[...]. J Biol Chem 2005
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Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain.
Katherine J Kopeikina, George A Carlson, Rose Pitstick, Adam E Ludvigson, Alan Peters, Jennifer I Luebke, Robert M Koffie, Matthew P Frosch, Bradley T Hyman, Tara L Spires-Jones. Am J Pathol 2011
Katherine J Kopeikina, George A Carlson, Rose Pitstick, Adam E Ludvigson, Alan Peters, Jennifer I Luebke, Robert M Koffie, Matthew P Frosch, Bradley T Hyman, Tara L Spires-Jones. Am J Pathol 2011
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Oxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease.
Eric Tönnies, Eugenia Trushina. J Alzheimers Dis 2017
Eric Tönnies, Eugenia Trushina. J Alzheimers Dis 2017
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Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease.
P Hemachandra Reddy, M Flint Beal. Trends Mol Med 2008
P Hemachandra Reddy, M Flint Beal. Trends Mol Med 2008
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Mitochondria-Division Inhibitor 1 Protects Against Amyloid-β induced Mitochondrial Fragmentation and Synaptic Damage in Alzheimer's Disease.
P Hemachandra Reddy, Maria Manczak, XiangLing Yin. J Alzheimers Dis 2017
P Hemachandra Reddy, Maria Manczak, XiangLing Yin. J Alzheimers Dis 2017
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The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses.
Zheng Li, Ken-Ichi Okamoto, Yasunori Hayashi, Morgan Sheng. Cell 2004
Zheng Li, Ken-Ichi Okamoto, Yasunori Hayashi, Morgan Sheng. Cell 2004
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Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients.
Xinglong Wang, Bo Su, Hisashi Fujioka, Xiongwei Zhu. Am J Pathol 2008
Xinglong Wang, Bo Su, Hisashi Fujioka, Xiongwei Zhu. Am J Pathol 2008
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The Alzheimer's disease mitochondrial cascade hypothesis.
Russell H Swerdlow, Jeffrey M Burns, Shaharyar M Khan. J Alzheimers Dis 2010
Russell H Swerdlow, Jeffrey M Burns, Shaharyar M Khan. J Alzheimers Dis 2010
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A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients.
I Maurer, S Zierz, H J Möller. Neurobiol Aging 2000
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Synaptic mitochondrial pathology in Alzheimer's disease.
Heng Du, Lan Guo, Shirley ShiDu Yan. Antioxid Redox Signal 2012
Heng Du, Lan Guo, Shirley ShiDu Yan. Antioxid Redox Signal 2012
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Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease.
Eugenia Trushina, Emirhan Nemutlu, Song Zhang, Trace Christensen, Jon Camp, Janny Mesa, Ammar Siddiqui, Yasushi Tamura, Hiromi Sesaki, Thomas M Wengenack,[...]. PLoS One 2012
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8
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