Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
Times Cited: 2470
Times Cited: 2470
Times Cited
Times Co-cited
Similarity
32
ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.
Andrew N Blackford, Stephen P Jackson. Mol Cell 2017
Andrew N Blackford, Stephen P Jackson. Mol Cell 2017
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DNA damage sensing by the ATM and ATR kinases.
Alexandre Maréchal, Lee Zou. Cold Spring Harb Perspect Biol 2013
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10
Non-homologous DNA end joining and alternative pathways to double-strand break repair.
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
9
DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
9
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
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9
Endogenous DNA Damage as a Source of Genomic Instability in Cancer.
Anthony Tubbs, André Nussenzweig. Cell 2017
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8
Repair Pathway Choices and Consequences at the Double-Strand Break.
Raphael Ceccaldi, Beatrice Rondinelli, Alan D D'Andrea. Trends Cell Biol 2016
Raphael Ceccaldi, Beatrice Rondinelli, Alan D D'Andrea. Trends Cell Biol 2016
8
DNA double-strand breaks: signaling, repair and the cancer connection.
K K Khanna, S P Jackson. Nat Genet 2001
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7
Causes and consequences of replication stress.
Michelle K Zeman, Karlene A Cimprich. Nat Cell Biol 2014
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7
Playing the end game: DNA double-strand break repair pathway choice.
J Ross Chapman, Martin R G Taylor, Simon J Boulton. Mol Cell 2012
J Ross Chapman, Martin R G Taylor, Simon J Boulton. Mol Cell 2012
7
Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors.
Fabio Pessina, Fabio Giavazzi, Yandong Yin, Ubaldo Gioia, Valerio Vitelli, Alessandro Galbiati, Sara Barozzi, Massimiliano Garre, Amanda Oldani, Andrew Flaus,[...]. Nat Cell Biol 2019
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8
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.
François Aymard, Beatrix Bugler, Christine K Schmidt, Emmanuelle Guillou, Pierre Caron, Sébastien Briois, Jason S Iacovoni, Virginie Daburon, Kyle M Miller, Stephen P Jackson,[...]. Nat Struct Mol Biol 2014
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6
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation.
Christopher J Bakkenist, Michael B Kastan. Nature 2003
Christopher J Bakkenist, Michael B Kastan. Nature 2003
6
The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer.
Joanne Smith, Lye Mun Tho, Naihan Xu, David A Gillespie. Adv Cancer Res 2010
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6
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks.
Manuel Stucki, Julie A Clapperton, Duaa Mohammad, Michael B Yaffe, Stephen J Smerdon, Stephen P Jackson. Cell 2005
Manuel Stucki, Julie A Clapperton, Duaa Mohammad, Michael B Yaffe, Stephen J Smerdon, Stephen P Jackson. Cell 2005
6
A role for small RNAs in DNA double-strand break repair.
Wei Wei, Zhaoqing Ba, Min Gao, Yang Wu, Yanting Ma, Simon Amiard, Charles I White, Jannie Michaela Rendtlew Danielsen, Yun-Gui Yang, Yijun Qi. Cell 2012
Wei Wei, Zhaoqing Ba, Min Gao, Yang Wu, Yanting Ma, Simon Amiard, Charles I White, Jannie Michaela Rendtlew Danielsen, Yun-Gui Yang, Yijun Qi. Cell 2012
6
Site-specific DICER and DROSHA RNA products control the DNA-damage response.
Sofia Francia, Flavia Michelini, Alka Saxena, Dave Tang, Michiel de Hoon, Viviana Anelli, Marina Mione, Piero Carninci, Fabrizio d'Adda di Fagagna. Nature 2012
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6
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139.
E P Rogakou, D R Pilch, A H Orr, V S Ivanova, W M Bonner. J Biol Chem 1998
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6
Mechanisms of DNA damage, repair, and mutagenesis.
Nimrat Chatterjee, Graham C Walker. Environ Mol Mutagen 2017
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6
Replication stress and cancer.
Hélène Gaillard, Tatiana García-Muse, Andrés Aguilera. Nat Rev Cancer 2015
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6
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson, Tobias B Richardson, Manuela Santarosa, Krystyna J Dillon, Ian Hickson, Charlotte Knights,[...]. Nature 2005
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6
Double-strand break repair: 53BP1 comes into focus.
Stephanie Panier, Simon J Boulton. Nat Rev Mol Cell Biol 2014
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6
State-of-the-art strategies for targeting the DNA damage response in cancer.
Patrick G Pilié, Chad Tang, Gordon B Mills, Timothy A Yap. Nat Rev Clin Oncol 2019
Patrick G Pilié, Chad Tang, Gordon B Mills, Timothy A Yap. Nat Rev Clin Oncol 2019
5
5
Mitotic progression following DNA damage enables pattern recognition within micronuclei.
Shane M Harding, Joseph L Benci, Jerome Irianto, Dennis E Discher, Andy J Minn, Roger A Greenberg. Nature 2017
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5
Targeting the replication stress response in cancer.
Josep V Forment, Mark J O'Connor. Pharmacol Ther 2018
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7
RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response.
Alexandre Maréchal, Lee Zou. Cell Res 2015
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5
DNA damage checkpoint kinases in cancer.
Hannah L Smith, Harriet Southgate, Deborah A Tweddle, Nicola J Curtin. Expert Rev Mol Med 2020
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22
Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection.
Roopesh Anand, Lepakshi Ranjha, Elda Cannavo, Petr Cejka. Mol Cell 2016
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5
Replication fork reversal in eukaryotes: from dead end to dynamic response.
Kai J Neelsen, Massimo Lopes. Nat Rev Mol Cell Biol 2015
Kai J Neelsen, Massimo Lopes. Nat Rev Mol Cell Biol 2015
5
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex.
Ji-Hoon Lee, Tanya T Paull. Science 2005
Ji-Hoon Lee, Tanya T Paull. Science 2005
5
Sae2 promotes dsDNA endonuclease activity within Mre11-Rad50-Xrs2 to resect DNA breaks.
Elda Cannavo, Petr Cejka. Nature 2014
Elda Cannavo, Petr Cejka. Nature 2014
5
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
Shuhei Matsuoka, Bryan A Ballif, Agata Smogorzewska, E Robert McDonald, Kristen E Hurov, Ji Luo, Corey E Bakalarski, Zhenming Zhao, Nicole Solimini, Yaniv Lerenthal,[...]. Science 2007
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5
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance.
Jiri Lukas, Claudia Lukas, Jiri Bartek. Nat Cell Biol 2011
Jiri Lukas, Claudia Lukas, Jiri Bartek. Nat Cell Biol 2011
5
cGAS surveillance of micronuclei links genome instability to innate immunity.
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
5
BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment.
Giuseppina D'Alessandro, Donna Rose Whelan, Sean Michael Howard, Valerio Vitelli, Xavier Renaudin, Marek Adamowicz, Fabio Iannelli, Corey Winston Jones-Weinert, MiYoung Lee, Valentina Matti,[...]. Nat Commun 2018
Giuseppina D'Alessandro, Donna Rose Whelan, Sean Michael Howard, Valerio Vitelli, Xavier Renaudin, Marek Adamowicz, Fabio Iannelli, Corey Winston Jones-Weinert, MiYoung Lee, Valentina Matti,[...]. Nat Commun 2018
6
Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair.
Wei-Ting Lu, Ben R Hawley, George L Skalka, Robert A Baldock, Ewan M Smith, Aldo S Bader, Michal Malewicz, Felicity Z Watts, Ania Wilczynska, Martin Bushell. Nat Commun 2018
Wei-Ting Lu, Ben R Hawley, George L Skalka, Robert A Baldock, Ewan M Smith, Aldo S Bader, Michal Malewicz, Felicity Z Watts, Ania Wilczynska, Martin Bushell. Nat Commun 2018
5
Homologous recombination and the repair of DNA double-strand breaks.
William Douglass Wright, Shanaya Shital Shah, Wolf-Dietrich Heyer. J Biol Chem 2018
William Douglass Wright, Shanaya Shital Shah, Wolf-Dietrich Heyer. J Biol Chem 2018
5
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.
Aziz Sancar, Laura A Lindsey-Boltz, Keziban Unsal-Kaçmaz, Stuart Linn. Annu Rev Biochem 2004
Aziz Sancar, Laura A Lindsey-Boltz, Keziban Unsal-Kaçmaz, Stuart Linn. Annu Rev Biochem 2004
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The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
5
5
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling.
Francesca Mattiroli, Joseph H A Vissers, Willem J van Dijk, Pauline Ikpa, Elisabetta Citterio, Wim Vermeulen, Jurgen A Marteijn, Titia K Sixma. Cell 2012
Francesca Mattiroli, Joseph H A Vissers, Willem J van Dijk, Pauline Ikpa, Elisabetta Citterio, Wim Vermeulen, Jurgen A Marteijn, Titia K Sixma. Cell 2012
5
Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN.
Nausica Arnoult, Adriana Correia, Jiao Ma, Anna Merlo, Sara Garcia-Gomez, Marija Maric, Marco Tognetti, Christopher W Benner, Simon J Boulton, Alan Saghatelian,[...]. Nature 2017
Nausica Arnoult, Adriana Correia, Jiao Ma, Anna Merlo, Sara Garcia-Gomez, Marija Maric, Marco Tognetti, Christopher W Benner, Simon J Boulton, Alan Saghatelian,[...]. Nature 2017
5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.