Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
Times Cited: 2654
Times Cited: 2654
Times Cited
Times Co-cited
Similarity
20
Non-homologous DNA end joining and alternative pathways to double-strand break repair.
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
16
DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
9
DNA damage sensing by the ATM and ATR kinases.
Alexandre Maréchal, Lee Zou. Cold Spring Harb Perspect Biol 2013
Alexandre Maréchal, Lee Zou. Cold Spring Harb Perspect Biol 2013
9
Mechanisms of DNA damage, repair, and mutagenesis.
Nimrat Chatterjee, Graham C Walker. Environ Mol Mutagen 2017
Nimrat Chatterjee, Graham C Walker. Environ Mol Mutagen 2017
9
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139.
E P Rogakou, D R Pilch, A H Orr, V S Ivanova, W M Bonner. J Biol Chem 1998
E P Rogakou, D R Pilch, A H Orr, V S Ivanova, W M Bonner. J Biol Chem 1998
9
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.
Amélie Fradet-Turcotte, Marella D Canny, Cristina Escribano-Díaz, Alexandre Orthwein, Charles C Y Leung, Hao Huang, Marie-Claude Landry, Julianne Kitevski-LeBlanc, Sylvie M Noordermeer, Frank Sicheri,[...]. Nature 2013
Amélie Fradet-Turcotte, Marella D Canny, Cristina Escribano-Díaz, Alexandre Orthwein, Charles C Y Leung, Hao Huang, Marie-Claude Landry, Julianne Kitevski-LeBlanc, Sylvie M Noordermeer, Frank Sicheri,[...]. Nature 2013
8
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson, Tobias B Richardson, Manuela Santarosa, Krystyna J Dillon, Ian Hickson, Charlotte Knights,[...]. Nature 2005
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson, Tobias B Richardson, Manuela Santarosa, Krystyna J Dillon, Ian Hickson, Charlotte Knights,[...]. Nature 2005
8
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.
Aziz Sancar, Laura A Lindsey-Boltz, Keziban Unsal-Kaçmaz, Stuart Linn. Annu Rev Biochem 2004
Aziz Sancar, Laura A Lindsey-Boltz, Keziban Unsal-Kaçmaz, Stuart Linn. Annu Rev Biochem 2004
8
ATM phosphorylates histone H2AX in response to DNA double-strand breaks.
S Burma, B P Chen, M Murphy, A Kurimasa, D J Chen. J Biol Chem 2001
S Burma, B P Chen, M Murphy, A Kurimasa, D J Chen. J Biol Chem 2001
8
Endogenous DNA Damage as a Source of Genomic Instability in Cancer.
Anthony Tubbs, André Nussenzweig. Cell 2017
Anthony Tubbs, André Nussenzweig. Cell 2017
7
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling.
Francesca Mattiroli, Joseph H A Vissers, Willem J van Dijk, Pauline Ikpa, Elisabetta Citterio, Wim Vermeulen, Jurgen A Marteijn, Titia K Sixma. Cell 2012
Francesca Mattiroli, Joseph H A Vissers, Willem J van Dijk, Pauline Ikpa, Elisabetta Citterio, Wim Vermeulen, Jurgen A Marteijn, Titia K Sixma. Cell 2012
7
Double-strand break end resection and repair pathway choice.
Lorraine S Symington, Jean Gautier. Annu Rev Genet 2011
Lorraine S Symington, Jean Gautier. Annu Rev Genet 2011
7
Playing the end game: DNA double-strand break repair pathway choice.
J Ross Chapman, Martin R G Taylor, Simon J Boulton. Mol Cell 2012
J Ross Chapman, Martin R G Taylor, Simon J Boulton. Mol Cell 2012
7
ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.
Andrew N Blackford, Stephen P Jackson. Mol Cell 2017
Andrew N Blackford, Stephen P Jackson. Mol Cell 2017
7
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
7
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
7
Causes and consequences of replication stress.
Michelle K Zeman, Karlene A Cimprich. Nat Cell Biol 2014
Michelle K Zeman, Karlene A Cimprich. Nat Cell Biol 2014
7
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation.
Christopher J Bakkenist, Michael B Kastan. Nature 2003
Christopher J Bakkenist, Michael B Kastan. Nature 2003
7
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.
Raphael Ceccaldi, Jessica C Liu, Ravindra Amunugama, Ildiko Hajdu, Benjamin Primack, Mark I R Petalcorin, Kevin W O'Connor, Panagiotis A Konstantinopoulos, Stephen J Elledge, Simon J Boulton,[...]. Nature 2015
Raphael Ceccaldi, Jessica C Liu, Ravindra Amunugama, Ildiko Hajdu, Benjamin Primack, Mark I R Petalcorin, Kevin W O'Connor, Panagiotis A Konstantinopoulos, Stephen J Elledge, Simon J Boulton,[...]. Nature 2015
7
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks.
Manuel Stucki, Julie A Clapperton, Duaa Mohammad, Michael B Yaffe, Stephen J Smerdon, Stephen P Jackson. Cell 2005
Manuel Stucki, Julie A Clapperton, Duaa Mohammad, Michael B Yaffe, Stephen J Smerdon, Stephen P Jackson. Cell 2005
6
The essential kinase ATR: ensuring faithful duplication of a challenging genome.
Joshua C Saldivar, David Cortez, Karlene A Cimprich. Nat Rev Mol Cell Biol 2017
Joshua C Saldivar, David Cortez, Karlene A Cimprich. Nat Rev Mol Cell Biol 2017
6
Therapeutic opportunities within the DNA damage response.
Laurence H Pearl, Amanda C Schierz, Simon E Ward, Bissan Al-Lazikani, Frances M G Pearl. Nat Rev Cancer 2015
Laurence H Pearl, Amanda C Schierz, Simon E Ward, Bissan Al-Lazikani, Frances M G Pearl. Nat Rev Cancer 2015
6
Double-strand break repair: 53BP1 comes into focus.
Stephanie Panier, Simon J Boulton. Nat Rev Mol Cell Biol 2014
Stephanie Panier, Simon J Boulton. Nat Rev Mol Cell Biol 2014
6
Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.
Pedro A Mateos-Gomez, Fade Gong, Nidhi Nair, Kyle M Miller, Eros Lazzerini-Denchi, Agnel Sfeir. Nature 2015
Pedro A Mateos-Gomez, Fade Gong, Nidhi Nair, Kyle M Miller, Eros Lazzerini-Denchi, Agnel Sfeir. Nature 2015
6
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation.
Tom Stiff, Mark O'Driscoll, Nicole Rief, Kuniyoshi Iwabuchi, Markus Löbrich, Penny A Jeggo. Cancer Res 2004
Tom Stiff, Mark O'Driscoll, Nicole Rief, Kuniyoshi Iwabuchi, Markus Löbrich, Penny A Jeggo. Cancer Res 2004
6
Replication stress and cancer.
Hélène Gaillard, Tatiana García-Muse, Andrés Aguilera. Nat Rev Cancer 2015
Hélène Gaillard, Tatiana García-Muse, Andrés Aguilera. Nat Rev Cancer 2015
5
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications.
Sophie E Polo, Stephen P Jackson. Genes Dev 2011
Sophie E Polo, Stephen P Jackson. Genes Dev 2011
5
Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair.
Ye Xu, Marina K Ayrapetov, Chang Xu, Ozge Gursoy-Yuzugullu, Yiduo Hu, Brendan D Price. Mol Cell 2012
Ye Xu, Marina K Ayrapetov, Chang Xu, Ozge Gursoy-Yuzugullu, Yiduo Hu, Brendan D Price. Mol Cell 2012
5
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.
Tina Thorslund, Anita Ripplinger, Saskia Hoffmann, Thomas Wild, Michael Uckelmann, Bine Villumsen, Takeo Narita, Titia K Sixma, Chunaram Choudhary, Simon Bekker-Jensen,[...]. Nature 2015
Tina Thorslund, Anita Ripplinger, Saskia Hoffmann, Thomas Wild, Michael Uckelmann, Bine Villumsen, Takeo Narita, Titia K Sixma, Chunaram Choudhary, Simon Bekker-Jensen,[...]. Nature 2015
5
Removal of H2A.Z by INO80 promotes homologous recombination.
Hanan E Alatwi, Jessica A Downs. EMBO Rep 2015
Hanan E Alatwi, Jessica A Downs. EMBO Rep 2015
6
Biomarker-Guided Development of DNA Repair Inhibitors.
James M Cleary, Andrew J Aguirre, Geoffrey I Shapiro, Alan D D'Andrea. Mol Cell 2020
James M Cleary, Andrew J Aguirre, Geoffrey I Shapiro, Alan D D'Andrea. Mol Cell 2020
8
State-of-the-art strategies for targeting the DNA damage response in cancer.
Patrick G Pilié, Chad Tang, Gordon B Mills, Timothy A Yap. Nat Rev Clin Oncol 2019
Patrick G Pilié, Chad Tang, Gordon B Mills, Timothy A Yap. Nat Rev Clin Oncol 2019
5
Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place.
Panagiotis Kotsantis, Eva Petermann, Simon J Boulton. Cancer Discov 2018
Panagiotis Kotsantis, Eva Petermann, Simon J Boulton. Cancer Discov 2018
5
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more.
Yosef Shiloh, Yael Ziv. Nat Rev Mol Cell Biol 2013
Yosef Shiloh, Yael Ziv. Nat Rev Mol Cell Biol 2013
5
The DNA damage response: implications for tumor responses to radiation and chemotherapy.
Michael Goldstein, Michael B Kastan. Annu Rev Med 2015
Michael Goldstein, Michael B Kastan. Annu Rev Med 2015
5
Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation.
Mo Li, Xiaochun Yu. Cancer Cell 2013
Mo Li, Xiaochun Yu. Cancer Cell 2013
5
Genomic instability--an evolving hallmark of cancer.
Simona Negrini, Vassilis G Gorgoulis, Thanos D Halazonetis. Nat Rev Mol Cell Biol 2010
Simona Negrini, Vassilis G Gorgoulis, Thanos D Halazonetis. Nat Rev Mol Cell Biol 2010
5
Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
Qi Hu, Maria Victoria Botuyan, Debiao Zhao, Gaofeng Cui, Elie Mer, Georges Mer. Nature 2021
Qi Hu, Maria Victoria Botuyan, Debiao Zhao, Gaofeng Cui, Elie Mer, Georges Mer. Nature 2021
35
Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer.
Chun-Chin Chen, Weiran Feng, Pei Xin Lim, Elizabeth M Kass, Maria Jasin. Annu Rev Cancer Biol 2018
Chun-Chin Chen, Weiran Feng, Pei Xin Lim, Elizabeth M Kass, Maria Jasin. Annu Rev Cancer Biol 2018
5
Moving Mountains-The BRCA1 Promotion of DNA Resection.
Ruth M Densham, Joanna R Morris. Front Mol Biosci 2019
Ruth M Densham, Joanna R Morris. Front Mol Biosci 2019
22
The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.
Aleem Syed, John A Tainer. Annu Rev Biochem 2018
Aleem Syed, John A Tainer. Annu Rev Biochem 2018
5
Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair.
Nicole Bennardo, Anita Cheng, Nick Huang, Jeremy M Stark. PLoS Genet 2008
Nicole Bennardo, Anita Cheng, Nick Huang, Jeremy M Stark. PLoS Genet 2008
5
Unravelling mechanisms of p53-mediated tumour suppression.
Kathryn T Bieging, Stephano Spano Mello, Laura D Attardi. Nat Rev Cancer 2014
Kathryn T Bieging, Stephano Spano Mello, Laura D Attardi. Nat Rev Cancer 2014
5
BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination.
Jordan R Becker, Gillian Clifford, Clara Bonnet, Anja Groth, Marcus D Wilson, J Ross Chapman. Nature 2021
Jordan R Becker, Gillian Clifford, Clara Bonnet, Anja Groth, Marcus D Wilson, J Ross Chapman. Nature 2021
20
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.
Helen Davies, Dominik Glodzik, Sandro Morganella, Lucy R Yates, Johan Staaf, Xueqing Zou, Manasa Ramakrishna, Sancha Martin, Sandrine Boyault, Anieta M Sieuwerts,[...]. Nat Med 2017
Helen Davies, Dominik Glodzik, Sandro Morganella, Lucy R Yates, Johan Staaf, Xueqing Zou, Manasa Ramakrishna, Sancha Martin, Sandrine Boyault, Anieta M Sieuwerts,[...]. Nat Med 2017
5
Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer.
Mansoor R Mirza, Bradley J Monk, Jørn Herrstedt, Amit M Oza, Sven Mahner, Andrés Redondo, Michel Fabbro, Jonathan A Ledermann, Domenica Lorusso, Ignace Vergote,[...]. N Engl J Med 2016
Mansoor R Mirza, Bradley J Monk, Jørn Herrstedt, Amit M Oza, Sven Mahner, Andrés Redondo, Michel Fabbro, Jonathan A Ledermann, Domenica Lorusso, Ignace Vergote,[...]. N Engl J Med 2016
5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.