A citation-based method for searching scientific literature

Richard A Miller, David E Harrison, C M Astle, Joseph A Baur, Angela Rodriguez Boyd, Rafael de Cabo, Elizabeth Fernandez, Kevin Flurkey, Martin A Javors, James F Nelson, Carlos J Orihuela, Scott Pletcher, Zelton Dave Sharp, David Sinclair, Joseph W Starnes, J Erby Wilkinson, Nancy L Nadon, Randy Strong. J Gerontol A Biol Sci Med Sci 2011
Times Cited: 581







List of co-cited articles
1092 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
David E Harrison, Randy Strong, Zelton Dave Sharp, James F Nelson, Clinton M Astle, Kevin Flurkey, Nancy L Nadon, J Erby Wilkinson, Krystyna Frenkel, Christy S Carter,[...]. Nature 2009
65

Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction.
Richard A Miller, David E Harrison, Clinton M Astle, Elizabeth Fernandez, Kevin Flurkey, Melissa Han, Martin A Javors, Xinna Li, Nancy L Nadon, James F Nelson,[...]. Aging Cell 2014
294
34

Rapamycin slows aging in mice.
John E Wilkinson, Lisa Burmeister, Susan V Brooks, Chi-Chao Chan, Sabrina Friedline, David E Harrison, James F Hejtmancik, Nancy Nadon, Randy Strong, Lauren K Wood,[...]. Aging Cell 2012
394
30

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.
Randy Strong, Richard A Miller, Adam Antebi, Clinton M Astle, Molly Bogue, Martin S Denzel, Elizabeth Fernandez, Kevin Flurkey, Karyn L Hamilton, Dudley W Lamming,[...]. Aging Cell 2016
143
27

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
24

Metformin improves healthspan and lifespan in mice.
Alejandro Martin-Montalvo, Evi M Mercken, Sarah J Mitchell, Hector H Palacios, Patricia L Mote, Morten Scheibye-Knudsen, Ana P Gomes, Theresa M Ward, Robin K Minor, Marie-José Blouin,[...]. Nat Commun 2013
690
19

Rapamycin extends murine lifespan but has limited effects on aging.
Frauke Neff, Diana Flores-Dominguez, Devon P Ryan, Marion Horsch, Susanne Schröder, Thure Adler, Luciana Caminha Afonso, Juan Antonio Aguilar-Pimentel, Lore Becker, Lillian Garrett,[...]. J Clin Invest 2013
232
18

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice.
Alessandro Bitto, Takashi K Ito, Victor V Pineda, Nicolas J LeTexier, Heather Z Huang, Elissa Sutlief, Herman Tung, Nicholas Vizzini, Belle Chen, Kaleb Smith,[...]. Elife 2016
152
18

Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males.
David E Harrison, Randy Strong, David B Allison, Bruce N Ames, Clinton M Astle, Hani Atamna, Elizabeth Fernandez, Kevin Flurkey, Martin A Javors, Nancy L Nadon,[...]. Aging Cell 2014
195
18

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
Kevin J Pearson, Joseph A Baur, Kaitlyn N Lewis, Leonid Peshkin, Nathan L Price, Nazar Labinskyy, William R Swindell, Davida Kamara, Robin K Minor, Evelyn Perez,[...]. Cell Metab 2008
803
17

Resveratrol improves health and survival of mice on a high-calorie diet.
Joseph A Baur, Kevin J Pearson, Nathan L Price, Hamish A Jamieson, Carles Lerin, Avash Kalra, Vinayakumar V Prabhu, Joanne S Allard, Guillermo Lopez-Lluch, Kaitlyn Lewis,[...]. Nature 2006
16

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway.
Pankaj Kapahi, Brian M Zid, Tony Harper, Daniel Koslover, Viveca Sapin, Seymour Benzer. Curr Biol 2004
880
16

Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice.
Randy Strong, Richard A Miller, Clinton M Astle, Joseph A Baur, Rafael de Cabo, Elizabeth Fernandez, Wen Guo, Martin Javors, James L Kirkland, James F Nelson,[...]. J Gerontol A Biol Sci Med Sci 2013
121
15

Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
Dudley W Lamming, Lan Ye, Pekka Katajisto, Marcus D Goncalves, Maki Saitoh, Deanna M Stevens, James G Davis, Adam B Salmon, Arlan Richardson, Rexford S Ahima,[...]. Science 2012
727
15

Genetics: influence of TOR kinase on lifespan in C. elegans.
Tibor Vellai, Krisztina Takacs-Vellai, Yue Zhang, Attila L Kovacs, László Orosz, Fritz Müller. Nature 2003
723
15

mTOR is a key modulator of ageing and age-related disease.
Simon C Johnson, Peter S Rabinovitch, Matt Kaeberlein. Nature 2013
940
14

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.
Matt Kaeberlein, R Wilson Powers, Kristan K Steffen, Eric A Westman, Di Hu, Nick Dang, Emily O Kerr, Kathryn T Kirkland, Stanley Fields, Brian K Kennedy. Science 2005
907
14

Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster.
Ivana Bjedov, Janne M Toivonen, Fiona Kerr, Cathy Slack, Jake Jacobson, Andrea Foley, Linda Partridge. Cell Metab 2010
611
14

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.
Konrad T Howitz, Kevin J Bitterman, Haim Y Cohen, Dudley W Lamming, Siva Lavu, Jason G Wood, Robert E Zipkin, Phuong Chung, Anne Kisielewski, Li-Li Zhang,[...]. Nature 2003
13

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells.
Chong Chen, Yu Liu, Yang Liu, Pan Zheng. Sci Signal 2009
407
13

Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.
Colin Selman, Jennifer M A Tullet, Daniela Wieser, Elaine Irvine, Steven J Lingard, Agharul I Choudhury, Marc Claret, Hind Al-Qassab, Danielle Carmignac, Faruk Ramadani,[...]. Science 2009
760
13

Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice.
Vladimir N Anisimov, Mark A Zabezhinski, Irina G Popovich, Tatiana S Piskunova, Anna V Semenchenko, Margarita L Tyndyk, Maria N Yurova, Svetlana V Rosenfeld, Mikhail V Blagosklonny. Cell Cycle 2011
237
13

mTOR inhibition improves immune function in the elderly.
Joan B Mannick, Giuseppe Del Giudice, Maria Lattanzi, Nicholas M Valiante, Jens Praestgaard, Baisong Huang, Michael A Lonetto, Holden T Maecker, John Kovarik, Simon Carson,[...]. Sci Transl Med 2014
357
13

Rapamycin extends life and health in C57BL/6 mice.
Yiqiang Zhang, Alex Bokov, John Gelfond, Vanessa Soto, Yuji Ikeno, Gene Hubbard, Vivian Diaz, Lauren Sloane, Keith Maslin, Stephen Treaster,[...]. J Gerontol A Biol Sci Med Sci 2014
181
13

Acarbose improves health and lifespan in aging HET3 mice.
David E Harrison, Randy Strong, Silvestre Alavez, Clinton Michael Astle, John DiGiovanni, Elizabeth Fernandez, Kevin Flurkey, Michael Garratt, Jonathan A L Gelfond, Martin A Javors,[...]. Aging Cell 2019
33
39

Metformin as a Tool to Target Aging.
Nir Barzilai, Jill P Crandall, Stephen B Kritchevsky, Mark A Espeland. Cell Metab 2016
426
13

Extending healthy life span--from yeast to humans.
Luigi Fontana, Linda Partridge, Valter D Longo. Science 2010
12

Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice.
Randy Strong, Richard A Miller, Clinton M Astle, Robert A Floyd, Kevin Flurkey, Kenneth L Hensley, Martin A Javors, Christiaan Leeuwenburgh, James F Nelson, Ennio Ongini,[...]. Aging Cell 2008
193
12

Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
597
11

TORC1 inhibition enhances immune function and reduces infections in the elderly.
Joan B Mannick, Melody Morris, Hans-Ulrich P Hockey, Guglielmo Roma, Martin Beibel, Kenneth Kulmatycki, Mollie Watkins, Tea Shavlakadze, Weihua Zhou, Dean Quinn,[...]. Sci Transl Med 2018
162
11

Extension of chronological life span in yeast by decreased TOR pathway signaling.
R Wilson Powers, Matt Kaeberlein, Seth D Caldwell, Brian K Kennedy, Stanley Fields. Genes Dev 2006
650
11

TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO.
Stacey Robida-Stubbs, Kira Glover-Cutter, Dudley W Lamming, Masaki Mizunuma, Sri Devi Narasimhan, Elke Neumann-Haefelin, David M Sabatini, T Keith Blackwell. Cell Metab 2012
347
11

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
10

Rapamycin extends maximal lifespan in cancer-prone mice.
Vladimir N Anisimov, Mark A Zabezhinski, Irina G Popovich, Tatiana S Piskunova, Anna V Semenchenko, Margarita L Tyndyk, Maria N Yurova, Marina P Antoch, Mikhail V Blagosklonny. Am J Pathol 2010
185
10

Late-life rapamycin treatment reverses age-related heart dysfunction.
James M Flynn, Monique N O'Leary, Christopher A Zambataro, Emmeline C Academia, Michael P Presley, Brittany J Garrett, Artem Zykovich, Sean D Mooney, Randy Strong, Clifford J Rosen,[...]. Aging Cell 2013
177
10


Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome.
Wilson C Fok, Yidong Chen, Alex Bokov, Yiqiang Zhang, Adam B Salmon, Vivian Diaz, Martin Javors, William H Wood, Yongqing Zhang, Kevin G Becker,[...]. PLoS One 2014
83
12

Geroscience: linking aging to chronic disease.
Brian K Kennedy, Shelley L Berger, Anne Brunet, Judith Campisi, Ana Maria Cuervo, Elissa S Epel, Claudio Franceschi, Gordon J Lithgow, Richard I Morimoto, Jeffrey E Pessin,[...]. Cell 2014
834
10

The search for antiaging interventions: from elixirs to fasting regimens.
Rafael de Cabo, Didac Carmona-Gutierrez, Michel Bernier, Michael N Hall, Frank Madeo. Cell 2014
190
9

Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart.
Dao-Fu Dai, Pabalu P Karunadharma, Ying A Chiao, Nathan Basisty, David Crispin, Edward J Hsieh, Tony Chen, Haiwei Gu, Danijel Djukovic, Daniel Raftery,[...]. Aging Cell 2014
174
9

Sirtuin activators mimic caloric restriction and delay ageing in metazoans.
Jason G Wood, Blanka Rogina, Siva Lavu, Konrad Howitz, Stephen L Helfand, Marc Tatar, David Sinclair. Nature 2004
9

A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs.
Silvan R Urfer, Tammi L Kaeberlein, Susan Mailheau, Philip J Bergman, Kate E Creevy, Daniel E L Promislow, Matt Kaeberlein. Geroscience 2017
80
11

Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/- mice.
Elena A Komarova, Marina P Antoch, Liliya R Novototskaya, Olga B Chernova, Geraldine Paszkiewicz, Olga V Leontieva, Mikhail V Blagosklonny, Andrei V Gudkov. Aging (Albany NY) 2012
111
9


Duration of rapamycin treatment has differential effects on metabolism in mice.
Yimin Fang, Reyhan Westbrook, Cristal Hill, Ravneet K Boparai, Oge Arum, Adam Spong, Feiya Wang, Martin A Javors, Jie Chen, Liou Y Sun,[...]. Cell Metab 2013
125
9



Spermidine in health and disease.
Frank Madeo, Tobias Eisenberg, Federico Pietrocola, Guido Kroemer. Science 2018
281
8

Caloric restriction improves health and survival of rhesus monkeys.
Julie A Mattison, Ricki J Colman, T Mark Beasley, David B Allison, Joseph W Kemnitz, George S Roth, Donald K Ingram, Richard Weindruch, Rafael de Cabo, Rozalyn M Anderson. Nat Commun 2017
349
8

Rapamycin extends life span of Rb1+/- mice by inhibiting neuroendocrine tumors.
Carolina B Livi, Rulon L Hardman, Barbara A Christy, Sherry G Dodds, Diane Jones, Charnae Williams, Randy Strong, Alex Bokov, Martin A Javors, Yuji Ikeno,[...]. Aging (Albany NY) 2013
61
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.