A citation-based method for searching scientific literature

Yasushi Ogawa, Yosuke Nonaka, Toshiyasu Goto, Eriko Ohnishi, Toshiyuki Hiramatsu, Isao Kii, Miyo Yoshida, Teikichi Ikura, Hiroshi Onogi, Hiroshi Shibuya, Takamitsu Hosoya, Nobutoshi Ito, Masatoshi Hagiwara. Nat Commun 2010
Times Cited: 183







List of co-cited articles
850 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.
Nora Göckler, Guillermo Jofre, Chrisovalantis Papadopoulos, Ulf Soppa, Francisco J Tejedor, Walter Becker. FEBS J 2009
169
35

Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.
Tania Tahtouh, Jonathan M Elkins, Panagis Filippakopoulos, Meera Soundararajan, Guillaume Burgy, Emilie Durieu, Claude Cochet, Ralf S Schmid, Donald C Lo, Florent Delhommel,[...]. J Med Chem 2012
141
33

The role of DYRK1A in neurodegenerative diseases.
Jerzy Wegiel, Cheng-Xin Gong, Yu-Wen Hwang. FEBS J 2011
170
27

10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A.
Hannes Falke, Apirat Chaikuad, Anja Becker, Nadège Loaëc, Olivier Lozach, Samira Abu Jhaisha, Walter Becker, Peter G Jones, Lutz Preu, Knut Baumann,[...]. J Med Chem 2015
57
43

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.
Peng Wang, Juan-Carlos Alvarez-Perez, Dan P Felsenfeld, Hongtao Liu, Sharmila Sivendran, Aaron Bender, Anil Kumar, Roberto Sanchez, Donald K Scott, Adolfo Garcia-Ocaña,[...]. Nat Med 2015
235
25

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.
Weijun Shen, Brandon Taylor, Qihui Jin, Van Nguyen-Tran, Shelly Meeusen, You-Qing Zhang, Anwesh Kamireddy, Austin Swafford, Andrew F Powers, John Walker,[...]. Nat Commun 2015
128
24

Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics.
Dnyandev B Jarhad, Karishma K Mashelkar, Hong-Rae Kim, Minsoo Noh, Lak Shin Jeong. J Med Chem 2018
53
45

Selective inhibition of the kinase DYRK1A by targeting its folding process.
Isao Kii, Yuto Sumida, Toshiyasu Goto, Rie Sonamoto, Yukiko Okuno, Suguru Yoshida, Tomoe Kato-Sumida, Yuka Koike, Minako Abe, Yosuke Nonaka,[...]. Nat Commun 2016
49
46


Activation, regulation, and inhibition of DYRK1A.
Walter Becker, Wolfgang Sippl. FEBS J 2011
142
22


A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.
Séverine Coutadeur, Hélène Benyamine, Laurence Delalonde, Catherine de Oliveira, Bertrand Leblond, Alicia Foucourt, Thierry Besson, Anne-Sophie Casagrande, Thierry Taverne, Angélique Girard,[...]. J Neurochem 2015
78
28

The selectivity of protein kinase inhibitors: a further update.
Jenny Bain, Lorna Plater, Matt Elliott, Natalia Shpiro, C James Hastie, Hilary McLauchlan, Iva Klevernic, J Simon C Arthur, Dario R Alessi, Philip Cohen. Biochem J 2007
20

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.
Meera Soundararajan, Annette K Roos, Pavel Savitsky, Panagis Filippakopoulos, Arminja N Kettenbach, Jesper V Olsen, Scott A Gerber, Jeyanthy Eswaran, Stefan Knapp, Jonathan M Elkins. Structure 2013
97
20

Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.
Ercument Dirice, Deepika Walpita, Amedeo Vetere, Bennett C Meier, Sevim Kahraman, Jiang Hu, Vlado Dančík, Sean M Burns, Tamara J Gilbert, David E Olson,[...]. Diabetes 2016
119
20

DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis.
P Fernández-Martínez, C Zahonero, P Sánchez-Gómez. Mol Cell Oncol 2015
61
32

Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature.
Thu Lan Nguyen, Corinne Fruit, Yann Hérault, Laurent Meijer, Thierry Besson. Expert Opin Ther Pat 2017
36
50

DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications.
Ramzi Abbassi, Terrance G Johns, Michael Kassiou, Lenka Munoz. Pharmacol Ther 2015
96
18


The specificities of protein kinase inhibitors: an update.
Jenny Bain, Hilary McLauchlan, Matthew Elliott, Philip Cohen. Biochem J 2003
18

A chemical with proven clinical safety rescues Down-syndrome-related phenotypes in through DYRK1A inhibition.
Hyeongki Kim, Kyu-Sun Lee, Ae-Kyeong Kim, Miri Choi, Kwangman Choi, Mingu Kang, Seung-Wook Chi, Min-Sung Lee, Jeong-Soo Lee, So-Young Lee,[...]. Dis Model Mech 2016
57
31

DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.
Soo-Ryoon Ryoo, Hey Kyeong Jeong, Chinzorig Radnaabazar, Jin-Ju Yoo, Hyun-Jeong Cho, Hye-Won Lee, In-Sook Kim, Young-Hee Cheon, Young Soo Ahn, Sul-Hee Chung,[...]. J Biol Chem 2007
172
17

Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ25-35 peptide administration in mice.
Gaëlle Naert, Valentine Ferré, Johann Meunier, Emeline Keller, Susanna Malmström, Laurent Givalois, François Carreaux, Jean-Pierre Bazureau, Tangui Maurice. Eur Neuropsychopharmacol 2015
37
45

β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites.
Danielle Frost, Bessie Meechoovet, Tong Wang, Stephen Gately, Marco Giorgetti, Irina Shcherbakova, Travis Dunckley. PLoS One 2011
107
16

DYRK1A: a potential drug target for multiple Down syndrome neuropathologies.
Walter Becker, Ulf Soppa, Francisco J Tejedor. CNS Neurol Disord Drug Targets 2014
67
22

DYRK1A kinase inhibitors with emphasis on cancer.
A Ionescu, F Dufrasne, M Gelbcke, I Jabin, R Kiss, D Lamoral-Theys. Mini Rev Med Chem 2012
51
29

The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.
Ryo Kimura, Kouzin Kamino, Mitsuko Yamamoto, Aidaralieva Nuripa, Tomoyuki Kida, Hiroaki Kazui, Ryota Hashimoto, Toshihisa Tanaka, Takashi Kudo, Hidehisa Yamagata,[...]. Hum Mol Genet 2007
184
15

Development of DANDYs, new 3,5-diaryl-7-azaindoles demonstrating potent DYRK1A kinase inhibitory activity.
Stéphanie Gourdain, Julien Dairou, Clément Denhez, Linh Chi Bui, Fernando Rodrigues-Lima, Nathalie Janel, Jean M Delabar, Kevin Cariou, Robert H Dodd. J Med Chem 2013
38
39

Probing the ATP-Binding Pocket of Protein Kinase DYRK1A with Benzothiazole Fragment Molecules.
Ulli Rothweiler, Wenche Stensen, Bjørn Olav Brandsdal, Johan Isaksson, Frederick Alan Leeson, Richard Alan Engh, John S Mjøen Svendsen. J Med Chem 2016
26
57

DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.
Larisa Litovchick, Laurence A Florens, Selene K Swanson, Michael P Washburn, James A DeCaprio. Genes Dev 2011
178
15

Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth.
Natividad Pozo, Cristina Zahonero, Paloma Fernández, Jose M Liñares, Angel Ayuso, Masatoshi Hagiwara, Angel Pérez, Jose R Ricoy, Aurelio Hernández-Laín, Juan M Sepúlveda,[...]. J Clin Invest 2013
86
17

Development of Kinase-Selective, Harmine-Based DYRK1A Inhibitors that Induce Pancreatic Human β-Cell Proliferation.
Kunal Kumar, Peng Wang, Roberto Sanchez, Ethan A Swartz, Andrew F Stewart, Robert J DeVita. J Med Chem 2018
38
39

Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.
Pamela A Lochhead, Gary Sibbet, Nick Morrice, Vaughn Cleghon. Cell 2005
214
14


Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.
Rafael De la Torre, Susana De Sola, Meritxell Pons, Arnaud Duchon, María Martínez de Lagran, Magí Farré, Montserrat Fitó, Bessy Benejam, Klaus Langohr, Joan Rodriguez,[...]. Mol Nutr Food Res 2014
178
14

Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
Soo-Ryoon Ryoo, Hyun-Jeong Cho, Hye-Won Lee, Hey Kyeong Jeong, Chinzorig Radnaabazar, Yeun-Soo Kim, Min-Jeong Kim, Mi-Young Son, Hyemyung Seo, Sul-Hee Chung,[...]. J Neurochem 2008
140
14

The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation.
Ulf Soppa, Julian Schumacher, Victoria Florencio Ortiz, Tobias Pasqualon, Francisco J Tejedor, Walter Becker. Cell Cycle 2014
103
14

DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives.
Fernanda Neumann, Stéphanie Gourdain, Christelle Albac, Alain D Dekker, Linh Chi Bui, Julien Dairou, Isabelle Schmitz-Afonso, Nathalie Hue, Fernando Rodrigues-Lima, Jean M Delabar,[...]. Sci Rep 2018
33
42

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
Mansour Debdab, François Carreaux, Steven Renault, Meera Soundararajan, Oleg Fedorov, Panagis Filippakopoulos, Olivier Lozach, Lucie Babault, Tania Tahtouh, Blandine Baratte,[...]. J Med Chem 2011
97
13

DYRK1A inhibition as potential treatment for Alzheimer's disease.
Silvia Stotani, Fabrizio Giordanetto, Federico Medda. Future Med Chem 2016
38
34

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.
Joseph R Arron, Monte M Winslow, Alberto Polleri, Ching-Pin Chang, Hai Wu, Xin Gao, Joel R Neilson, Lei Chen, Jeremy J Heit, Seung K Kim,[...]. Nature 2006
500
13

Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.
Fayçal Guedj, Catherine Sébrié, Isabelle Rivals, Aurelie Ledru, Evelyne Paly, Jean C Bizot, Desmond Smith, Edward Rubin, Brigitte Gillet, Mariona Arbones,[...]. PLoS One 2009
142
13

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome.
Fei Liu, Zhihou Liang, Jerzy Wegiel, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal, Narayan Ramakrishna, Cheng-Xin Gong. FASEB J 2008
162
12

Dyrk1A-mediated phosphorylation of Presenilin 1: a functional link between Down syndrome and Alzheimer's disease.
Young Shin Ryu, So Young Park, Min-Su Jung, Song-Hee Yoon, Mi-Yang Kwen, Sun-Young Lee, Sun-Hee Choi, Chinzorig Radnaabazar, Mi-Kyoung Kim, Hangun Kim,[...]. J Neurochem 2010
65
18

Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors.
Katharina Rüben, Anne Wurzlbauer, Agnes Walte, Wolfgang Sippl, Franz Bracher, Walter Becker. PLoS One 2015
37
32

Synthesis of chromeno[3,4-b]indoles as Lamellarin D analogues: a novel DYRK1A inhibitor class.
Cleopatra Neagoie, Emeline Vedrenne, Frédéric Buron, Jean-Yves Mérour, Sorin Rosca, Stéphane Bourg, Olivier Lozach, Laurent Meijer, Brigitte Baldeyrou, Amelie Lansiaux,[...]. Eur J Med Chem 2012
54
22

CC-401 Promotes β-Cell Replication via Pleiotropic Consequences of DYRK1A/B Inhibition.
Yassan Abdolazimi, Zhengshan Zhao, Sooyeon Lee, Haixia Xu, Paul Allegretti, Timothy M Horton, Benjamin Yeh, Hannah P Moeller, Robert J Nichols, David McCutcheon,[...]. Endocrinology 2018
38
31

Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells.
Peng Wang, Esra Karakose, Hongtao Liu, Ethan Swartz, Courtney Ackeifi, Viktor Zlatanic, Jessica Wilson, Bryan J González, Aaron Bender, Karen K Takane,[...]. Cell Metab 2019
83
14

An Unusual Binding Model of the Methyl 9-Anilinothiazolo[5,4-f] quinazoline-2-carbimidates (EHT 1610 and EHT 5372) Confers High Selectivity for Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases.
Apirat Chaikuad, Julien Diharce, Martin Schröder, Alicia Foucourt, Bertrand Leblond, Anne-Sophie Casagrande, Laurent Désiré, Pascal Bonnet, Stefan Knapp, Thierry Besson. J Med Chem 2016
28
39

Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice.
Akiko Nakano-Kobayashi, Tomonari Awaya, Isao Kii, Yuto Sumida, Yukiko Okuno, Suguru Yoshida, Tomoe Sumida, Haruhisa Inoue, Takamitsu Hosoya, Masatoshi Hagiwara. Proc Natl Acad Sci U S A 2017
51
21


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.